Compile Data Set for Download or QSAR

Found 961 hits with Last Name = 'thomson' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) Show SMILES CN(C)CCSc1cccc(n1)C1CCCCC1 Show InChI InChI=1S/C15H24N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h6,9-10,13H,3-5,7-8,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139353 ((2-tert-Butylsulfanyl-ethyl)-dimethyl-amine | CHEM...) Show SMILES CN(C)CCSC(C)(C)C Show InChI InChI=1S/C8H19NS/c1-8(2,3)10-7-6-9(4)5/h6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139361 (2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...) Show SMILES CN(C)CCSc1cccc(Br)n1 Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) Show SMILES CN(C)CCSc1cccc(n1)C1CCCCC1 Show InChI InChI=1S/C15H24N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h6,9-10,13H,3-5,7-8,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139357 (CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C13H16N2S2/c1-15(2)8-9-16-13-14-12(10-17-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139353 ((2-tert-Butylsulfanyl-ethyl)-dimethyl-amine | CHEM...) Show SMILES CN(C)CCSC(C)(C)C Show InChI InChI=1S/C8H19NS/c1-8(2,3)10-7-6-9(4)5/h6-7H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139352 (CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...) Show SMILES CN(C)CCSc1nc(cs1)C(C)(C)C Show InChI InChI=1S/C11H20N2S2/c1-11(2,3)9-8-15-10(12-9)14-7-6-13(4)5/h8H,6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139356 (CHEMBL350166 | Dimethyl-[2-(4-pyridin-4-yl-thiazol...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccncc1 Show InChI InChI=1S/C12H15N3S2/c1-15(2)7-8-16-12-14-11(9-17-12)10-3-5-13-6-4-10/h3-6,9H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139361 (2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...) Show SMILES CN(C)CCSc1cccc(Br)n1 Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139360 (CHEMBL161846 | [2-(Benzothiazol-2-ylsulfanyl)-ethy...) Show SMILES CN(C)CCSc1nc2ccccc2s1 Show InChI InChI=1S/C11H14N2S2/c1-13(2)7-8-14-11-12-9-5-3-4-6-10(9)15-11/h3-6H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139356 (CHEMBL350166 | Dimethyl-[2-(4-pyridin-4-yl-thiazol...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccncc1 Show InChI InChI=1S/C12H15N3S2/c1-15(2)7-8-16-12-14-11(9-17-12)10-3-5-13-6-4-10/h3-6,9H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139353 ((2-tert-Butylsulfanyl-ethyl)-dimethyl-amine | CHEM...) Show SMILES CN(C)CCSC(C)(C)C Show InChI InChI=1S/C8H19NS/c1-8(2,3)10-7-6-9(4)5/h6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139363 (CHEMBL162071 | Dimethyl-[2-(2-phenyl-pyridin-4-yls...) Show SMILES CN(C)CCSc1ccnc(c1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)10-11-18-14-8-9-16-15(12-14)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139356 (CHEMBL350166 | Dimethyl-[2-(4-pyridin-4-yl-thiazol...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccncc1 Show InChI InChI=1S/C12H15N3S2/c1-15(2)7-8-16-12-14-11(9-17-12)10-3-5-13-6-4-10/h3-6,9H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139358 (CHEMBL160903 | Dimethyl-[2-(5-methyl-4-phenyl-thia...) Show SMILES CN(C)CCSc1nc(c(C)s1)-c1ccccc1 Show InChI InChI=1S/C14H18N2S2/c1-11-13(12-7-5-4-6-8-12)15-14(18-11)17-10-9-16(2)3/h4-8H,9-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50178273 (CHEMBL202775 | N-((2-(2-cyclopropoxy-5-(trifluorom...) Show SMILES Fc1ccc(cc1)C12CC(CNS(=O)(=O)c3ccccc3)C(CCC1NCc1cc(OC(F)(F)F)ccc1OC1CC1)N2 Show InChI InChI=1S/C31H33F4N3O4S/c32-23-8-6-22(7-9-23)30-17-21(19-37-43(39,40)26-4-2-1-3-5-26)27(38-30)13-15-29(30)36-18-20-16-25(42-31(33,34)35)12-14-28(20)41-24-10-11-24/h1-9,12,14,16,21,24,27,29,36-38H,10-11,13,15,17-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139356 (CHEMBL350166 | Dimethyl-[2-(4-pyridin-4-yl-thiazol...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccncc1 Show InChI InChI=1S/C12H15N3S2/c1-15(2)7-8-16-12-14-11(9-17-12)10-3-5-13-6-4-10/h3-6,9H,7-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139357 (CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C13H16N2S2/c1-15(2)8-9-16-13-14-12(10-17-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) Show SMILES CN(C)CCSc1cccc(n1)C1CCCCC1 Show InChI InChI=1S/C15H24N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h6,9-10,13H,3-5,7-8,11-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50178267 (CHEMBL201362 | N-(2-methoxy-5-(trifluoromethoxy)be...) Show SMILES COc1ccc(OC(F)(F)F)cc1CNC1CCC2CCC1(N2)c1ccccc1 Show InChI InChI=1S/C22H25F3N2O2/c1-28-19-9-8-18(29-22(23,24)25)13-15(19)14-26-20-10-7-17-11-12-21(20,27-17)16-5-3-2-4-6-16/h2-6,8-9,13,17,20,26-27H,7,10-12,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139361 (2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...) Show SMILES CN(C)CCSc1cccc(Br)n1 Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50178271 ((2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino...) Show SMILES OCC1CC2(NC1CCC2NCc1cc(OC(F)(F)F)ccc1OC1CC1)c1ccccc1 Show InChI InChI=1S/C25H29F3N2O3/c26-25(27,28)33-20-8-10-22(32-19-6-7-19)16(12-20)14-29-23-11-9-21-17(15-31)13-24(23,30-21)18-4-2-1-3-5-18/h1-5,8,10,12,17,19,21,23,29-31H,6-7,9,11,13-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139353 ((2-tert-Butylsulfanyl-ethyl)-dimethyl-amine | CHEM...) Show SMILES CN(C)CCSC(C)(C)C Show InChI InChI=1S/C8H19NS/c1-8(2,3)10-7-6-9(4)5/h6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50178270 (CHEMBL382803 | N-(2-cyclopropoxy-5-(trifluorometho...) Show SMILES FC(F)(F)Oc1ccc(OC2CC2)c(CNC2CCC3CCC2(N3)c2ccccc2)c1 Show InChI InChI=1S/C24H27F3N2O2/c25-24(26,27)31-20-9-10-21(30-19-7-8-19)16(14-20)15-28-22-11-6-18-12-13-23(22,29-18)17-4-2-1-3-5-17/h1-5,9-10,14,18-19,22,28-29H,6-8,11-13,15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50178269 (CHEMBL382848 | N-((2-(2-cyclopropoxy-5-(trifluorom...) Show SMILES CS(=O)(=O)NCC1CC2(NC1CCC2NCc1cc(OC(F)(F)F)ccc1OC1CC1)c1ccc(F)cc1 Show InChI InChI=1S/C26H31F4N3O4S/c1-38(34,35)32-15-17-13-25(18-2-4-19(27)5-3-18)24(11-9-22(17)33-25)31-14-16-12-21(37-26(28,29)30)8-10-23(16)36-20-6-7-20/h2-5,8,10,12,17,20,22,24,31-33H,6-7,9,11,13-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) Show SMILES CN(C)CCSc1cccc(n1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h3-10H,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139357 (CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C13H16N2S2/c1-15(2)8-9-16-13-14-12(10-17-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139360 (CHEMBL161846 | [2-(Benzothiazol-2-ylsulfanyl)-ethy...) Show SMILES CN(C)CCSc1nc2ccccc2s1 Show InChI InChI=1S/C11H14N2S2/c1-13(2)7-8-14-11-12-9-5-3-4-6-10(9)15-11/h3-6H,7-8H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139361 (2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine...) Show SMILES CN(C)CCSc1cccc(Br)n1 Show InChI InChI=1S/C9H13BrN2S/c1-12(2)6-7-13-9-5-3-4-8(10)11-9/h3-5H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139360 (CHEMBL161846 | [2-(Benzothiazol-2-ylsulfanyl)-ethy...) Show SMILES CN(C)CCSc1nc2ccccc2s1 Show InChI InChI=1S/C11H14N2S2/c1-13(2)7-8-14-11-12-9-5-3-4-6-10(9)15-11/h3-6H,7-8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139357 (CHEMBL345803 | Dimethyl-[2-(4-phenyl-thiazol-2-yls...) Show SMILES CN(C)CCSc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C13H16N2S2/c1-15(2)8-9-16-13-14-12(10-17-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139360 (CHEMBL161846 | [2-(Benzothiazol-2-ylsulfanyl)-ethy...) Show SMILES CN(C)CCSc1nc2ccccc2s1 Show InChI InChI=1S/C11H14N2S2/c1-13(2)7-8-14-11-12-9-5-3-4-6-10(9)15-11/h3-6H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139352 (CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...) Show SMILES CN(C)CCSc1nc(cs1)C(C)(C)C Show InChI InChI=1S/C11H20N2S2/c1-11(2,3)9-8-15-10(12-9)14-7-6-13(4)5/h8H,6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139354 (1-[6-(2-Dimethylamino-ethylsulfanyl)-pyridin-2-yl]...) Show SMILES CN(C)CCSc1cccc(n1)C1(O)CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-17(2)11-12-19-14-8-6-7-13(16-14)15(18)9-4-3-5-10-15/h6-8,18H,3-5,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50139352 (CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...) Show SMILES CN(C)CCSc1nc(cs1)C(C)(C)C Show InChI InChI=1S/C11H20N2S2/c1-11(2,3)9-8-15-10(12-9)14-7-6-13(4)5/h8H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139363 (CHEMBL162071 | Dimethyl-[2-(2-phenyl-pyridin-4-yls...) Show SMILES CN(C)CCSc1ccnc(c1)-c1ccccc1 Show InChI InChI=1S/C15H18N2S/c1-17(2)10-11-18-14-8-9-16-15(12-14)13-6-4-3-5-7-13/h3-9,12H,10-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139359 (CHEMBL159223 | Dimethyl-[2-(5-phenyl-2H-[1,2,4]tri...) Show SMILES CN(C)CCSc1nnc([nH]1)-c1ccccc1 Show InChI InChI=1S/C12H16N4S/c1-16(2)8-9-17-12-13-11(14-15-12)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3,(H,13,14,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) Show SMILES CN(C)CCSc1cccc(n1)C1CCCCC1 Show InChI InChI=1S/C15H24N2S/c1-17(2)11-12-18-15-10-6-9-14(16-15)13-7-4-3-5-8-13/h6,9-10,13H,3-5,7-8,11-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50178274 (CHEMBL202141 | N-(2-chloro-5-(trifluoromethoxy)ben...) Show SMILES FC(F)(F)Oc1ccc(Cl)c(CNC2CCC3CCC2(N3)c2ccccc2)c1 Show InChI InChI=1S/C21H22ClF3N2O/c22-18-8-7-17(28-21(23,24)25)12-14(18)13-26-19-9-6-16-10-11-20(19,27-16)15-4-2-1-3-5-15/h1-5,7-8,12,16,19,26-27H,6,9-11,13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50067935 ((2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-p...) Show SMILES COc1ccc(OC(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C20H23F3N2O2/c1-26-18-10-9-16(27-20(21,22)23)12-15(18)13-25-17-8-5-11-24-19(17)14-6-3-2-4-7-14/h2-4,6-7,9-10,12,17,19,24-25H,5,8,11,13H2,1H3/t17-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50139352 (CHEMBL161203 | [2-(4-tert-Butyl-thiazol-2-ylsulfan...) Show SMILES CN(C)CCSc1nc(cs1)C(C)(C)C Show InChI InChI=1S/C11H20N2S2/c1-11(2,3)9-8-15-10(12-9)14-7-6-13(4)5/h8H,6-7H2,1-5H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50139362 (CHEMBL434477 | Dimethyl-[2-(5-phenyl-thiazol-2-yls...) Show SMILES CN(C)CCSc1ncc(s1)-c1ccccc1 Show InChI InChI=1S/C13H16N2S2/c1-15(2)8-9-16-13-14-10-12(17-13)11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM38260 (CHEMBL158287 | Dimethyl-[2-(5-phenyl-[1,3,4]oxadia...) Show SMILES CN(C)CCSc1nnc(o1)-c1ccccc1 Show InChI InChI=1S/C12H15N3OS/c1-15(2)8-9-17-12-14-13-11(16-12)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ...				Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50178266 (2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)...) Show SMILES OC(=O)C1CC2(NC1CCC2NCc1cc(OC(F)(F)F)ccc1OC1CC1)c1ccc(F)cc1 Show InChI InChI=1S/C25H26F4N2O4/c26-16-3-1-15(2-4-16)24-12-19(23(32)33)20(31-24)8-10-22(24)30-13-14-11-18(35-25(27,28)29)7-9-21(14)34-17-5-6-17/h1-4,7,9,11,17,19-20,22,30-31H,5-6,8,10,12-13H2,(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [35S]-labelled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 811-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.026 BindingDB Entry DOI: 10.7270/Q2JW8DGT
					More data for this Ligand-Target Pair

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