Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176019![]() ((R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperaz...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176024![]() (3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176044![]() (3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176049![]() (3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176035![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176021![]() (3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176042![]() (5-Chloro-3-{3-[4-(2,3-dihydro-benzo[1,4]dioxin-5-y...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176020![]() ((R)-8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176034![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-4H...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176045![]() (3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176041![]() ((S)-8-{4-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-piper...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176023![]() ((S)-8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176023![]() ((S)-8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176043![]() ((S)-8-{4-[3-(7-Fluoro-1H-indol-3-yl)-propyl]-piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176028![]() (5-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-1,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176032![]() (3-[3-(4-Chroman-5-yl-piperazin-1-yl)-propyl]-1H-in...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176039![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-2,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176025![]() (4-Chloro-3-{3-[4-(2,3-dihydro-benzo[1,4]dioxin-5-y...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176033![]() (5-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-3,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176029![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-3,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176036![]() (3-{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50029150![]() (3-(2-Piperidin-4-yl-ethyl)-1H-indole | CHEMBL27652...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176031![]() (6-Chloro-3-{3-[4-(2,3-dihydro-benzo[1,4]dioxin-5-y...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM21398![]() (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176031![]() (6-Chloro-3-{3-[4-(2,3-dihydro-benzo[1,4]dioxin-5-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176040![]() ((R)-8-{4-[3-(7-Fluoro-1H-indol-3-yl)-propyl]-piper...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354607![]() (CHEMBL1834337) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176022![]() (5-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-3-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354585![]() (CHEMBL1834226) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354585![]() (CHEMBL1834226) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176026![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-2,...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176043![]() ((S)-8-{4-[3-(7-Fluoro-1H-indol-3-yl)-propyl]-piper...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354608![]() (CHEMBL1834342) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176034![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-4H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176035![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-2-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176041![]() ((S)-8-{4-[3-(5-Fluoro-1H-indol-3-yl)-propyl]-piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176037![]() (3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-pipera...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354609![]() (CHEMBL1834348) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176040![]() ((R)-8-{4-[3-(7-Fluoro-1H-indol-3-yl)-propyl]-piper...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354610![]() (CHEMBL1834338) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354611![]() (CHEMBL1834347) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176019![]() ((R)-8-(4-(3-(5-fluoro-1H-indol-3-yl)propyl)piperaz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50004108![]() ((+-)-nicotine | (R,S)-nicotine | (RS)-nicotine | 3...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharmaceuticals Curated by PDSP Ki Database | Bioorg Med Chem Lett 18: 188-93 (2008) Article DOI: 10.1016/j.bmcl.2007.10.101 BindingDB Entry DOI: 10.7270/Q2C827W3 | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354612![]() (CHEMBL1834350) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50176026![]() (8-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-2,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-spiperone binding to human dopamine D2 receptor expressed in CHO cells | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176027![]() (5-{4-[3-(1H-Indol-3-yl)-propyl]-piperazin-1-yl}-1-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50230537![]() ((S)-3-(4-chlorophenyl)-N'-(4-chlorophenylsulfonyl)...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description Displacement of CP-55,940 binding from recombinant human cannabinoid receptor 1 expressed in CHO cells | J Med Chem 47: 627-43 (2004) Article DOI: 10.1021/jm031019q BindingDB Entry DOI: 10.7270/Q2610ZQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354613![]() (CHEMBL1834333) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50354585![]() (CHEMBL1834226) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Healthcare Products B.V. Curated by ChEMBL | Assay Description Displacement of [3H]-methyllysergic acid diethylamide from human 5-HT6 receptor expressed in CHO cells after 30 mins by liquid scintillation counting | J Med Chem 54: 7030-54 (2011) Article DOI: 10.1021/jm200466r BindingDB Entry DOI: 10.7270/Q2J103JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50176048![]() (7-Chloro-3-{3-[4-(2,3-dihydro-benzo[1,4]dioxin-5-y...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Solvay Pharma Curated by ChEMBL | Assay Description In vitro inhibitory constant against [3H]-paroxetine binding to rat frontal cortex membrane serotonin reuptake site | J Med Chem 48: 6855-69 (2005) Article DOI: 10.1021/jm050148z BindingDB Entry DOI: 10.7270/Q21C1WFP | |||||||||||
More data for this Ligand-Target Pair |
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