Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095997 (3',4',7-trihydroxyisoflavone | CHEMBL13486) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human recombinant MIF tautomerase | J Med Chem 52: 416-24 (2009) Article DOI: 10.1021/jm801100v BindingDB Entry DOI: 10.7270/Q208656D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399046 (CHEMBL2178862) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399047 (CHEMBL2178856) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399054 (CHEMBL2178851) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399062 (CHEMBL2178843) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399048 (CHEMBL2178861) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096003 (7-Hydroxy-3-phenyl-chromen-2-one | 7-hydroxy-3-phe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human recombinant MIF tautomerase | J Med Chem 52: 416-24 (2009) Article DOI: 10.1021/jm801100v BindingDB Entry DOI: 10.7270/Q208656D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096001 (7-Hydroxy-3-pyrazolo[1,5-a]pyridin-2-yl-chromen-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human recombinant MIF tautomerase | J Med Chem 52: 416-24 (2009) Article DOI: 10.1021/jm801100v BindingDB Entry DOI: 10.7270/Q208656D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399056 (CHEMBL2178849) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399051 (CHEMBL2178855) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50265450 (2-oxo-2-phenylethyl 7-hydroxy-2-oxo-2H-chromene-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human recombinant MIF tautomerase | J Med Chem 52: 416-24 (2009) Article DOI: 10.1021/jm801100v BindingDB Entry DOI: 10.7270/Q208656D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096006 (7-Hydroxy-3-(2-methyl-thiazol-4-yl)-chromen-2-one ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human recombinant MIF tautomerase | J Med Chem 52: 416-24 (2009) Article DOI: 10.1021/jm801100v BindingDB Entry DOI: 10.7270/Q208656D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399059 (CHEMBL2178846) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399049 (CHEMBL2178858) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50096008 (3-Acetyl-7-hydroxy-chromen-2-one | 3-acetyl-7-hydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human recombinant MIF tautomerase | J Med Chem 52: 416-24 (2009) Article DOI: 10.1021/jm801100v BindingDB Entry DOI: 10.7270/Q208656D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399053 (CHEMBL2178852) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399060 (CHEMBL2178845) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399065 (CHEMBL2178837) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399058 (CHEMBL2178847) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399057 (CHEMBL2178848) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50095995 (7-HYDROXY-2-OXO-CHROMENE-3-CARBOXYLIC ACID ETHYL E...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | 7.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human recombinant MIF tautomerase | J Med Chem 52: 416-24 (2009) Article DOI: 10.1021/jm801100v BindingDB Entry DOI: 10.7270/Q208656D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399050 (CHEMBL2178857) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399072 (CHEMBL2178826) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399055 (CHEMBL2178850) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399071 (CHEMBL2178828) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | 1.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399069 (CHEMBL2178830) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399074 (CHEMBL2178863) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399066 (CHEMBL2178833) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399073 (CHEMBL2178867) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.54E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399070 (CHEMBL2178829) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399067 (CHEMBL2178832) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.34E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399063 (CHEMBL2178841) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399064 (CHEMBL2178838) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399052 (CHEMBL2178853) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM61233 (4-[(3,4-diketo-1-naphthyl)amino]benzenesulfonamide...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 9.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50399047 (CHEMBL2178856) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human MIF | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399061 (CHEMBL2178844) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Plasmodium falciparum) | BDBM50399068 (CHEMBL2178831) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate... | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (Homo sapiens (Human)) | BDBM50399046 (CHEMBL2178862) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 2.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of human MIF | J Med Chem 55: 10148-59 (2012) Article DOI: 10.1021/jm301269s BindingDB Entry DOI: 10.7270/Q2FJ2HX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50322823 ((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GST-tagged human EGFR (668 to 1210 residues) expressed in baculovirus expression system using poly-Glu-Tyr (4:1) as substrate incubated... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM50584767 (CHEMBL5069609) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM50584778 (CHEMBL5080260) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM50357312 (IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50357312 (IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GST-tagged human EGFR (668 to 1210 residues) expressed in baculovirus expression system using poly-Glu-Tyr (4:1) as substrate incubated... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50584767 (CHEMBL5069609) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of GST-tagged human EGFR (668 to 1210 residues) expressed in baculovirus expression system using poly-Glu-Tyr (4:1) as substrate incubated... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM195875 (US9670213, Compound 020 N-(3-(2-(4-(4-methyl-1-pip...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM195881 (US9670213, Compound 026 N-(3-(2-(4-methoxyphenylam...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM50357312 (IBRUTINIB | PCI-32765 | US10124003, Ref. Ex. Compo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of BTK phosphorylation in human U-937 cells incubated for 4 hrs by Western blot assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM195861 (US9670213, Compound 006 N-(3-(2-(4-methoxyphenylam...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase BTK (Homo sapiens (Human)) | BDBM50584770 (CHEMBL5087793) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human BTK using poly-Glu-Tyr (4:1) as substrate incubated for 1 hr by ELISA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02208 BindingDB Entry DOI: 10.7270/Q2K93CFH | |||||||||||
More data for this Ligand-Target Pair |
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