Found 428 hits with Last Name = 'benyhe' and Initial = 's' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM21015
((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO Show InChI InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.00240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 mins |
J Med Chem 51: 173-7 (2008)
Article DOI: 10.1021/jm7010222
BindingDB Entry DOI: 10.7270/Q2ZS2XBN |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551316
(CHEMBL4776706)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@]2(O)C=C1)ccc3OC |r,c:36,TLB:3:4:12.11.9:14,33:5:12.11.9:14,4:13:16.15:31.32,12:13:16.15:31.32,THB:18:16:13.1:31.32| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.00630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50139013
((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H37N5O5/c33-25(18-23-13-15-24(38)16-14-23)32(42)37-17-7-12-28(37)31(41)36-27(20-22-10-5-2-6-11-22)30(40)35-26(29(34)39)19-21-8-3-1-4-9-21/h1-6,8-11,13-16,25-28,38H,7,12,17-20,33H2,(H2,34,39)(H,35,40)(H,36,41)/t25-,26-,27-,28-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.00950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 mins |
J Med Chem 51: 173-7 (2008)
Article DOI: 10.1021/jm7010222
BindingDB Entry DOI: 10.7270/Q2ZS2XBN |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551315
(CHEMBL4762529)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@]2(OC)C=C1)ccc3OC |r,c:37,TLB:3:4:12.11.9:14,34:5:12.11.9:14,4:13:16.15:32.33,12:13:16.15:32.33,THB:18:16:13.1:32.33| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551313
(CHEMBL4745764)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCC)[C@]2(O)C=C1)ccc3O |r,c:30,TLB:3:4:12.11.9:14,28:5:12.11.9:14,4:13:16.15:26.27,12:13:16.15:26.27,THB:18:16:13.1:26.27| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0136 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50551314
(CHEMBL4751305)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@]2(O)C=C1)ccc3O |r,c:36,TLB:3:4:12.11.9:14,33:5:12.11.9:14,4:13:16.15:31.32,12:13:16.15:31.32,THB:18:16:13.1:31.32| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]HS665 from KOR in guinea pig brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50551311
(CHEMBL4746512)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14C51CC[C@@]2(O)[C@H](C1)C(C)(C)O)ccc3O |r,TLB:3:4:15.14.9:17,28:5:15.14.9:17,THB:24:22:16.1:19.18,4:16:22.23:19.18,15:16:22.23:19.18| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]HS665 from KOR in guinea pig brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50229425
(CHEMBL401142 | Tyr-(R)-spiro-Aba-Gly-Phe-NH2)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@]11Cc2ccccc2CN(CC(=O)N[C@@H](Cc2ccccc2)C(N)=O)C1=O Show InChI InChI=1S/C33H37N5O5/c34-27(17-23-11-13-26(39)14-12-23)31(42)38-16-6-15-33(38)19-24-9-4-5-10-25(24)20-37(32(33)43)21-29(40)36-28(30(35)41)18-22-7-2-1-3-8-22/h1-5,7-14,27-28,39H,6,15-21,34H2,(H2,35,41)(H,36,40)/t27-,28-,33+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.0293 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 mins |
J Med Chem 51: 173-7 (2008)
Article DOI: 10.1021/jm7010222
BindingDB Entry DOI: 10.7270/Q2ZS2XBN |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551309
(CHEMBL4758369)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])(C(C)(C)O)[C@]2(OC)C=C1)ccc3O |r,c:29,TLB:3:4:12.11.9:14,27:5:12.11.9:14,4:13:16.15:25.26,12:13:16.15:25.26,THB:18:16:13.1:25.26| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0325 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551311
(CHEMBL4746512)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14C51CC[C@@]2(O)[C@H](C1)C(C)(C)O)ccc3O |r,TLB:3:4:15.14.9:17,28:5:15.14.9:17,THB:24:22:16.1:19.18,4:16:22.23:19.18,15:16:22.23:19.18| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0333 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551314
(CHEMBL4751305)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@]2(O)C=C1)ccc3O |r,c:36,TLB:3:4:12.11.9:14,33:5:12.11.9:14,4:13:16.15:31.32,12:13:16.15:31.32,THB:18:16:13.1:31.32| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.0435 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM81931
(CAM | CAS_56337-94-1 | N-cyclopropylmethylnorazido...)Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CC[C@@H](N=[N+]=[N-])[C@H]5Oc1c2[C@]45CCN3CC1CC1 Show InChI InChI=1S/C20H24N4O2/c21-23-22-14-5-4-13-15-9-12-3-6-16(25)18-17(12)20(13,19(14)26-18)7-8-24(15)10-11-1-2-11/h3,6,11,13-15,19,25H,1-2,4-5,7-10H2/t13-,14+,15+,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
kappa-type opioid receptor isoform 1
(Frog) | BDBM81931
(CAM | CAS_56337-94-1 | N-cyclopropylmethylnorazido...)Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CC[C@@H](N=[N+]=[N-])[C@H]5Oc1c2[C@]45CCN3CC1CC1 Show InChI InChI=1S/C20H24N4O2/c21-23-22-14-5-4-13-15-9-12-3-6-16(25)18-17(12)20(13,19(14)26-18)7-8-24(15)10-11-1-2-11/h3,6,11,13-15,19,25H,1-2,4-5,7-10H2/t13-,14+,15+,19+,20-/m0/s1 | PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
kappa-type opioid receptor isoform 1
(Frog) | BDBM81931
(CAM | CAS_56337-94-1 | N-cyclopropylmethylnorazido...)Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CC[C@@H](N=[N+]=[N-])[C@H]5Oc1c2[C@]45CCN3CC1CC1 Show InChI InChI=1S/C20H24N4O2/c21-23-22-14-5-4-13-15-9-12-3-6-16(25)18-17(12)20(13,19(14)26-18)7-8-24(15)10-11-1-2-11/h3,6,11,13-15,19,25H,1-2,4-5,7-10H2/t13-,14+,15+,19+,20-/m0/s1 | PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
kappa-type opioid receptor isoform 1
(Frog) | BDBM81931
(CAM | CAS_56337-94-1 | N-cyclopropylmethylnorazido...)Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CC[C@@H](N=[N+]=[N-])[C@H]5Oc1c2[C@]45CCN3CC1CC1 Show InChI InChI=1S/C20H24N4O2/c21-23-22-14-5-4-13-15-9-12-3-6-16(25)18-17(12)20(13,19(14)26-18)7-8-24(15)10-11-1-2-11/h3,6,11,13-15,19,25H,1-2,4-5,7-10H2/t13-,14+,15+,19+,20-/m0/s1 | PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM86261
(14-methoxymetopon | CAS_131575-03-6 | NSC_125489)Show SMILES COC12CCC(=O)C3(C)Oc4c5c(CC1N(C)CCC235)ccc4O |TLB:1:2:18.17.15:13.12.11,THB:3:2:18.17.15:13.12.11| Show InChI InChI=1S/C19H23NO4/c1-17-14(22)6-7-19(23-3)13-10-11-4-5-12(21)16(24-17)15(11)18(17,19)8-9-20(13)2/h4-5,13,21H,6-10H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by PDSP Ki Database
| |
Eur J Neurosci 18: 290-5 (2003)
Article DOI: 10.1046/j.1460-9568.2003.02744.x
BindingDB Entry DOI: 10.7270/Q2P55M37 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551319
(CHEMBL4753839)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCC)[C@]2(OC)C=C1)ccc3O |r,c:31,TLB:3:4:12.11.9:14,29:5:12.11.9:14,4:13:16.15:27.28,12:13:16.15:27.28,THB:18:16:13.1:27.28| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.177 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM81931
(CAM | CAS_56337-94-1 | N-cyclopropylmethylnorazido...)Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CC[C@@H](N=[N+]=[N-])[C@H]5Oc1c2[C@]45CCN3CC1CC1 Show InChI InChI=1S/C20H24N4O2/c21-23-22-14-5-4-13-15-9-12-3-6-16(25)18-17(12)20(13,19(14)26-18)7-8-24(15)10-11-1-2-11/h3,6,11,13-15,19,25H,1-2,4-5,7-10H2/t13-,14+,15+,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551307
(CHEMBL4754079)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14C51CC[C@@]2(OC)[C@H](C1)C(C)(C)O)ccc3O |r,TLB:3:4:15.14.9:17,29:5:15.14.9:17,THB:25:23:16.1:19.18,4:16:23.24:19.18,15:16:23.24:19.18| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551312
(CHEMBL4761619)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14C51CC[C@@]2(O)[C@]([H])(C1)[C@@](C)(O)C(C)(C)C)ccc3O |r,TLB:3:4:15.14.9:17,32:5:15.14.9:17,THB:25:22:16.1:19.18,4:16:22.24:19.18,15:16:22.24:19.18| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.218 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551317
(CHEMBL4764372)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@]2(OCC)C=C1)ccc3OC |r,c:38,TLB:3:4:12.11.9:14,35:5:12.11.9:14,4:13:16.15:33.34,12:13:16.15:33.34,THB:18:16:13.1:33.34| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.252 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50551312
(CHEMBL4761619)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14C51CC[C@@]2(O)[C@]([H])(C1)[C@@](C)(O)C(C)(C)C)ccc3O |r,TLB:3:4:15.14.9:17,32:5:15.14.9:17,THB:25:22:16.1:19.18,4:16:22.24:19.18,15:16:22.24:19.18| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.257 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]HS665 from KOR in guinea pig brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50551308
(CHEMBL4758814)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14C51CC[C@@]2(OC)[C@]([H])(C1)[C@@](C)(O)C(C)(C)C)ccc3O |r,TLB:3:4:15.14.9:17,33:5:15.14.9:17,THB:26:23:16.1:19.18,4:16:23.25:19.18,15:16:23.25:19.18| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]HS665 from KOR in guinea pig brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM81931
(CAM | CAS_56337-94-1 | N-cyclopropylmethylnorazido...)Show SMILES Oc1ccc2C[C@@H]3[C@@H]4CC[C@@H](N=[N+]=[N-])[C@H]5Oc1c2[C@]45CCN3CC1CC1 Show InChI InChI=1S/C20H24N4O2/c21-23-22-14-5-4-13-15-9-12-3-6-16(25)18-17(12)20(13,19(14)26-18)7-8-24(15)10-11-1-2-11/h3,6,11,13-15,19,25H,1-2,4-5,7-10H2/t13-,14+,15+,19+,20-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50551316
(CHEMBL4776706)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@]2(O)C=C1)ccc3OC |r,c:36,TLB:3:4:12.11.9:14,33:5:12.11.9:14,4:13:16.15:31.32,12:13:16.15:31.32,THB:18:16:13.1:31.32| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.321 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]HS665 from KOR in guinea pig brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551318
(CHEMBL4787652)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCC)[C@]2(OC)C=C1)ccc3OC |r,c:31,TLB:3:4:12.11.9:14,29:5:12.11.9:14,4:13:16.15:27.28,12:13:16.15:27.28,THB:18:16:13.1:27.28| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.326 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50229426
(CHEMBL399796 | Tyr-(S)-Aba-Gly-Phe-NH2)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)N[C@@H](Cc2ccccc2)C(N)=O)C1=O Show InChI InChI=1S/C30H33N5O5/c31-24(14-20-10-12-23(36)13-11-20)29(39)34-26-16-21-8-4-5-9-22(21)17-35(30(26)40)18-27(37)33-25(28(32)38)15-19-6-2-1-3-7-19/h1-13,24-26,36H,14-18,31H2,(H2,32,38)(H,33,37)(H,34,39)/t24-,25-,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.373 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain after 45 mins |
J Med Chem 51: 173-7 (2008)
Article DOI: 10.1021/jm7010222
BindingDB Entry DOI: 10.7270/Q2ZS2XBN |
More data for this
Ligand-Target Pair | |
kappa-type opioid receptor isoform 1
(Frog) | BDBM81935
(CAS_105618-26-6 | NSC_3034416 | Nor-BNI)Show SMILES Oc1ccc2CC(C3CC3)N3CCC45C(Oc1c24)c1[nH]c2C4Oc6c7c(CC(C8CC8)N8CCC47C(O)(C8)Cc2c1CC5(O)C3)ccc6O |TLB:7:6:12.11:44.42,43:42:6.5.4.17:12.11,28:27:35.37:32.33,THB:23:24:35.37:32.33,45:25:35.37:32.33,41:42:6.5.4.17:12.11,16:17:12.11:44.42,3:4:12.11:44.42,36:35:32.33:25.24.26.27| Show InChI InChI=1S/C40H43N3O6/c44-27-7-5-21-13-25(19-1-2-19)42-11-9-39-29(21)33(27)48-35(39)31-23(15-37(39,46)17-42)24-16-38(47)18-43-12-10-40(38)30-22(14-26(43)20-3-4-20)6-8-28(45)34(30)49-36(40)32(24)41-31/h5-8,19-20,25-26,35-36,41,44-47H,1-4,9-18H2 | PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551310
(CHEMBL4752367)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51CC[C@@]2(OC)[C@H](C1)C(C)(C)O)ccc3O |r,TLB:3:4:12.11.9:14,26:5:12.11.9:14,THB:22:20:13.1:16.15,4:13:20.21:16.15,12:13:20.21:16.15| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.435 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50139018
((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)Show SMILES C[C@H]([C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 Show InChI InChI=1S/C35H40N6O5/c1-21(23-8-3-2-4-9-23)31(32(37)43)40-33(44)29(19-24-20-38-28-11-6-5-10-26(24)28)39-34(45)30-12-7-17-41(30)35(46)27(36)18-22-13-15-25(42)16-14-22/h2-6,8-11,13-16,20-21,27,29-31,38,42H,7,12,17-19,36H2,1H3,(H2,37,43)(H,39,45)(H,40,44)/t21-,27-,29-,30-,31-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-endomorphin-2 from Opioid receptor mu 1 of rat brain membranes |
J Med Chem 47: 735-43 (2004)
Article DOI: 10.1021/jm0310028
BindingDB Entry DOI: 10.7270/Q2J965TS |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50202498
(CHEMBL219482 | H-Dmt-Tic-(2S,3S)-beta-MeCha-Phe-OH)Show SMILES C[C@H]([C@H](NC(=O)C1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O)C1CCCCC1 |r| Show InChI InChI=1S/C40H50N4O6/c1-24-18-31(45)19-25(2)32(24)22-33(41)39(48)44-23-30-17-11-10-16-29(30)21-35(44)37(46)43-36(26(3)28-14-8-5-9-15-28)38(47)42-34(40(49)50)20-27-12-6-4-7-13-27/h4,6-7,10-13,16-19,26,28,33-36,45H,5,8-9,14-15,20-23,41H2,1-3H3,(H,42,47)(H,43,46)(H,49,50)/t26-,33-,34-,35?,36-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ile5,6-deltorphin from delta opioid receptor in Wistar rat brain membrane |
J Med Chem 50: 328-33 (2007)
Article DOI: 10.1021/jm060721u
BindingDB Entry DOI: 10.7270/Q2SF2VVJ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM86261
(14-methoxymetopon | CAS_131575-03-6 | NSC_125489)Show SMILES COC12CCC(=O)C3(C)Oc4c5c(CC1N(C)CCC235)ccc4O |TLB:1:2:18.17.15:13.12.11,THB:3:2:18.17.15:13.12.11| Show InChI InChI=1S/C19H23NO4/c1-17-14(22)6-7-19(23-3)13-10-11-4-5-12(21)16(24-17)15(11)18(17,19)8-9-20(13)2/h4-5,13,21H,6-10H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by PDSP Ki Database
| |
Eur J Neurosci 18: 290-5 (2003)
Article DOI: 10.1046/j.1460-9568.2003.02744.x
BindingDB Entry DOI: 10.7270/Q2P55M37 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM21015
((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO Show InChI InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50000788
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50003571
((-)-3-Hydroxy-N-methylmorphinan hydrochloride (lev...)Show SMILES CN1CCC23CCCCC2C1Cc1ccc(O)cc31 |TLB:0:1:9:18.12.11,THB:17:18:9:1.3.2| Show InChI InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by PDSP Ki Database
| |
Eur J Neurosci 18: 290-5 (2003)
Article DOI: 10.1046/j.1460-9568.2003.02744.x
BindingDB Entry DOI: 10.7270/Q2P55M37 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50551308
(CHEMBL4758814)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14C51CC[C@@]2(OC)[C@]([H])(C1)[C@@](C)(O)C(C)(C)C)ccc3O |r,TLB:3:4:15.14.9:17,33:5:15.14.9:17,THB:26:23:16.1:19.18,4:16:23.25:19.18,15:16:23.25:19.18| | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.531 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50000092
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50202505
(CHEMBL197937 | H-Tyr-Tic-Cha-Phe-OH)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C37H44N4O6/c38-30(19-26-15-17-29(42)18-16-26)36(45)41-23-28-14-8-7-13-27(28)22-33(41)35(44)39-31(20-24-9-3-1-4-10-24)34(43)40-32(37(46)47)21-25-11-5-2-6-12-25/h2,5-8,11-18,24,30-33,42H,1,3-4,9-10,19-23,38H2,(H,39,44)(H,40,43)(H,46,47)/t30-,31-,32-,33?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]Ile5,6-deltorphin from delta opioid receptor in Wistar rat brain membrane |
J Med Chem 50: 328-33 (2007)
Article DOI: 10.1021/jm060721u
BindingDB Entry DOI: 10.7270/Q2SF2VVJ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50551317
(CHEMBL4764372)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCc4ccccc4)[C@]2(OCC)C=C1)ccc3OC |r,c:38,TLB:3:4:12.11.9:14,35:5:12.11.9:14,4:13:16.15:33.34,12:13:16.15:33.34,THB:18:16:13.1:33.34| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
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| PC cid
PC sid
UniChem
| Article
PubMed
| 0.682 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]HS665 from KOR in guinea pig brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50229426
(CHEMBL399796 | Tyr-(S)-Aba-Gly-Phe-NH2)Show SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H]1Cc2ccccc2CN(CC(=O)N[C@@H](Cc2ccccc2)C(N)=O)C1=O Show InChI InChI=1S/C30H33N5O5/c31-24(14-20-10-12-23(36)13-11-20)29(39)34-26-16-21-8-4-5-9-22(21)17-35(30(26)40)18-27(37)33-25(28(32)38)15-19-6-2-1-3-7-19/h1-13,24-26,36H,14-18,31H2,(H2,32,38)(H,33,37)(H,34,39)/t24-,25-,26-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.778 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]deltorphin 2 from delta opioid receptor in Wistar rat brain after 45 mins |
J Med Chem 51: 173-7 (2008)
Article DOI: 10.1021/jm7010222
BindingDB Entry DOI: 10.7270/Q2ZS2XBN |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM21014
((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C46H56N10O10/c1-27(51-43(63)35(47)21-31-13-17-33(57)18-14-31)41(61)49-25-39(59)53-37(23-29-9-5-3-6-10-29)45(65)55-56-46(66)38(24-30-11-7-4-8-12-30)54-40(60)26-50-42(62)28(2)52-44(64)36(48)22-32-15-19-34(58)20-16-32/h3-20,27-28,35-38,57-58H,21-26,47-48H2,1-2H3,(H,49,61)(H,50,62)(H,51,63)(H,52,64)(H,53,59)(H,54,60)(H,55,65)(H,56,66)/t27-,28-,35+,36+,37+,38+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Chieti-Pescara "G. d'Annunzio"
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from MOR in Wistar rat whole brain membranes after 45 mins by liquid scintillation counting method |
ACS Med Chem Lett 8: 858-863 (2017)
Article DOI: 10.1021/acsmedchemlett.7b00210
BindingDB Entry DOI: 10.7270/Q2S1853J |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50551313
(CHEMBL4745764)Show SMILES [H][C@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@]14C51C[C@]([H])([C@@](C)(O)CCC)[C@]2(O)C=C1)ccc3O |r,c:30,TLB:3:4:12.11.9:14,28:5:12.11.9:14,4:13:16.15:26.27,12:13:16.15:26.27,THB:18:16:13.1:26.27| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.796 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]HS665 from KOR in guinea pig brain membranes measured after 45 mins by scintillation counting method |
Citation and Details
Article DOI: 10.1016/j.ejmech.2020.112145
BindingDB Entry DOI: 10.7270/Q2W66QD3 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50139018
((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)Show SMILES C[C@H]([C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 Show InChI InChI=1S/C35H40N6O5/c1-21(23-8-3-2-4-9-23)31(32(37)43)40-33(44)29(19-24-20-38-28-11-6-5-10-26(24)28)39-34(45)30-12-7-17-41(30)35(46)27(36)18-22-13-15-25(42)16-14-22/h2-6,8-11,13-16,20-21,27,29-31,38,42H,7,12,17-19,36H2,1H3,(H2,37,43)(H,39,45)(H,40,44)/t21-,27-,29-,30-,31-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DAMGO from Opioid receptor mu 1 of rat brain membranes |
J Med Chem 47: 735-43 (2004)
Article DOI: 10.1021/jm0310028
BindingDB Entry DOI: 10.7270/Q2J965TS |
More data for this
Ligand-Target Pair | |
kappa-type opioid receptor isoform 1
(Frog) | BDBM50000788
((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 | PDB
Reactome pathway
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PC sid
UniChem
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| Article
PubMed
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50595851
(CHEMBL5192735)Show SMILES CCCC[C@@H](NC(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(N)=O |r| | PDB
UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
| Article
PubMed
| 0.920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00237
BindingDB Entry DOI: 10.7270/Q21Z48F7 |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50139015
((S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]...)Show SMILES C[C@H]([C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 Show InChI InChI=1S/C33H39N5O5/c1-21(24-11-6-3-7-12-24)29(30(35)40)37-31(41)27(20-22-9-4-2-5-10-22)36-32(42)28-13-8-18-38(28)33(43)26(34)19-23-14-16-25(39)17-15-23/h2-7,9-12,14-17,21,26-29,39H,8,13,18-20,34H2,1H3,(H2,35,40)(H,36,42)(H,37,41)/t21-,26-,27-,28-,29-/m0/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of the Hungarian Academy of Sciences
Curated by ChEMBL
| Assay Description
Displacement of [3H]-endomorphin-2 from Opioid receptor mu 1 of rat brain membranes |
J Med Chem 47: 735-43 (2004)
Article DOI: 10.1021/jm0310028
BindingDB Entry DOI: 10.7270/Q2J965TS |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Rattus norvegicus (rat)) | BDBM21015
((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)Show SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc1ccccc1)C(=O)NCCO Show InChI InChI=1S/C26H35N5O6/c1-17(30-25(36)21(27)14-19-8-10-20(33)11-9-19)24(35)29-16-23(34)31(2)22(26(37)28-12-13-32)15-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16,27H2,1-2H3,(H,28,37)(H,29,35)(H,30,36)/t17-,21+,22+/m1/s1 | PDB
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| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Chieti-Pescara"G. d'Annunzio"
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation counting based competition binding assay |
ACS Med Chem Lett 5: 1032-6 (2014)
Article DOI: 10.1021/ml500241n
BindingDB Entry DOI: 10.7270/Q23T9JS5 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50595850
(CHEMBL5188021)Show SMILES CCCC[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](CCCNC(N)=N)C(N)=O |r| | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00237
BindingDB Entry DOI: 10.7270/Q21Z48F7 |
More data for this
Ligand-Target Pair | |
kappa-type opioid receptor isoform 1
(Frog) | BDBM50000091
((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)Show SMILES CC[C@]12CCN(CC3CC3)C([C@@H]1C)C(=O)c1ccc(O)cc21 |TLB:6:5:13.21.15:11,14:13:11:5.3.4,THB:20:21:11:5.3.4| Show InChI InChI=1S/C19H25NO2/c1-3-19-8-9-20(11-13-4-5-13)17(12(19)2)18(22)15-7-6-14(21)10-16(15)19/h6-7,10,12-13,17,21H,3-5,8-9,11H2,1-2H3/t12-,17?,19-/m0/s1 | PDB
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UniProtKB/TrEMBL
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Rattus norvegicus (rat)) | BDBM50000092
((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)Show SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@H]3C=C[C@@H]4O)ccc5O |r,c:16,TLB:13:12:8.9.10:3.2.1| Show InChI InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1 | PDB
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| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biological Research Center of Hungarian Academy of Sciences
Curated by PDSP Ki Database
| |
Neurochem Res 15: 899-904 (1990)
Article DOI: 10.1007/bf00965909
BindingDB Entry DOI: 10.7270/Q25M6460 |
More data for this
Ligand-Target Pair | |
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