Compile Data Set for Download or QSAR

Found 63 hits with Last Name = 'bera' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144942 (2'-C-Me-guanosine | 2'-C-methyl-guanosine | 2'-C-m...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c1nc(N)[nH]c2=O Show InChI InChI=1S/C11H15N5O5/c1-11(20)6(18)4(2-17)21-9(11)16-3-13-5-7(16)14-10(12)15-8(5)19/h3-4,6,9,17-18,20H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,9-,11-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468707 (CHEMBL4290935) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OCc3ccccc3)c(OCc3ccccc3)c1)c2=O Show InChI InChI=1S/C31H26O6/c1-33-24-16-28(34-2)30-29(17-24)37-20-25(31(30)32)23-13-14-26(35-18-21-9-5-3-6-10-21)27(15-23)36-19-22-11-7-4-8-12-22/h3-17,20H,18-19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144937 (2-Amino-9-((2R,3R,5S)-3-hydroxy-5-hydroxymethyl-te...) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)C[C@H]1O Show InChI InChI=1S/C10H13N5O4/c11-10-13-7-6(8(18)14-10)12-3-15(7)9-5(17)1-4(2-16)19-9/h3-5,9,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,9+/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144947 (2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl...) Show SMILES CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c1nc(N)[nH]c2=O Show InChI InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144938 (2-Amino-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-hydr...) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](F)[C@H]1O Show InChI InChI=1S/C10H12FN5O4/c11-4-3(1-17)20-9(6(4)18)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144948 ((2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C11H15N5O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7-,10-,11-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468718 (CHEMBL4290044) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OC)c(OCc3ccc(cc3)C(F)(F)F)c1)c2=O Show InChI InChI=1S/C26H21F3O6/c1-31-18-11-22(33-3)24-23(12-18)35-14-19(25(24)30)16-6-9-20(32-2)21(10-16)34-13-15-4-7-17(8-5-15)26(27,28)29/h4-12,14H,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144949 ((2R,3R,4R,5R)-2-(2,6-diamino-9H-purin-9-yl)-5-(hyd...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)nc(N)nc12 Show InChI InChI=1S/C11H16N6O4/c1-11(20)6(19)4(2-18)21-9(11)17-3-14-5-7(12)15-10(13)16-8(5)17/h3-4,6,9,18-20H,2H2,1H3,(H4,12,13,15,16)/t4-,6-,9-,11-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468709 (CHEMBL4285647) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1ccc(-[#8]-[#6])c(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])c1)c2=O Show InChI InChI=1S/C23H24O6/c1-14(2)8-9-28-19-10-15(6-7-18(19)26-4)17-13-29-21-12-16(25-3)11-20(27-5)22(21)23(17)24/h6-8,10-13H,9H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468720 (CHEMBL4293248) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OCc3ccc(cc3)C(F)(F)F)c(OC)c1)c2=O Show InChI InChI=1S/C26H21F3O6/c1-31-18-11-22(33-3)24-23(12-18)35-14-19(25(24)30)16-6-9-20(21(10-16)32-2)34-13-15-4-7-17(8-5-15)26(27,28)29/h4-12,14H,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468708 (CHEMBL4291101) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1ccc(-[#8]-[#6])c(-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c1)c2=O Show InChI InChI=1S/C28H32O6/c1-18(2)8-7-9-19(3)12-13-33-24-14-20(10-11-23(24)31-5)22-17-34-26-16-21(30-4)15-25(32-6)27(26)28(22)29/h8,10-12,14-17H,7,9,13H2,1-6H3/b19-12+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468711 (CHEMBL4286606) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OC)c(OCc3ccccc3)c1)c2=O Show InChI InChI=1S/C25H22O6/c1-27-18-12-22(29-3)24-23(13-18)31-15-19(25(24)26)17-9-10-20(28-2)21(11-17)30-14-16-7-5-4-6-8-16/h4-13,15H,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144934 ((2R,3R,4R,5R)-2-(6-hydroxy-9H-purin-9-yl)-5-(hydro...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c1nc[nH]c2=O Show InChI InChI=1S/C11H14N4O5/c1-11(19)7(17)5(2-16)20-10(11)15-4-14-6-8(15)12-3-13-9(6)18/h3-5,7,10,16-17,19H,2H2,1H3,(H,12,13,18)/t5-,7-,10-,11-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468709 (CHEMBL4285647) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1ccc(-[#8]-[#6])c(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])c1)c2=O Show InChI InChI=1S/C23H24O6/c1-14(2)8-9-28-19-10-15(6-7-18(19)26-4)17-13-29-21-12-16(25-3)11-20(27-5)22(21)23(17)24/h6-8,10-13H,9H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468715 (CHEMBL4289866) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OCc3ccccc3)c(OC)c1)c2=O Show InChI InChI=1S/C25H22O6/c1-27-18-12-22(29-3)24-23(13-18)31-15-19(25(24)26)17-9-10-20(21(11-17)28-2)30-14-16-7-5-4-6-8-16/h4-13,15H,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468706 (CHEMBL4279181) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8]-[#6])c1)c2=O Show InChI InChI=1S/C23H24O6/c1-14(2)8-9-28-18-7-6-15(10-19(18)26-4)17-13-29-21-12-16(25-3)11-20(27-5)22(21)23(17)24/h6-8,10-13H,9H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468716 (CHEMBL4289632) Show SMILES COc1cc(OC)c2c(c1)occ(-c1cccc(OCc3ccc(cc3)C(F)(F)F)c1)c2=O Show InChI InChI=1S/C25H19F3O5/c1-30-19-11-21(31-2)23-22(12-19)33-14-20(24(23)29)16-4-3-5-18(10-16)32-13-15-6-8-17(9-7-15)25(26,27)28/h3-12,14H,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468706 (CHEMBL4279181) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1ccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8]-[#6])c1)c2=O Show InChI InChI=1S/C23H24O6/c1-14(2)8-9-28-18-7-6-15(10-19(18)26-4)17-13-29-21-12-16(25-3)11-20(27-5)22(21)23(17)24/h6-8,10-13H,9H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468718 (CHEMBL4290044) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OC)c(OCc3ccc(cc3)C(F)(F)F)c1)c2=O Show InChI InChI=1S/C26H21F3O6/c1-31-18-11-22(33-3)24-23(12-18)35-14-19(25(24)30)16-6-9-20(32-2)21(10-16)34-13-15-4-7-17(8-5-15)26(27,28)29/h4-12,14H,13H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468712 (CHEMBL4279361) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OC)c(OCc3ccc(cc3)C#N)c1)c2=O Show InChI InChI=1S/C26H21NO6/c1-29-19-11-23(31-3)25-24(12-19)33-15-20(26(25)28)18-8-9-21(30-2)22(10-18)32-14-17-6-4-16(13-27)5-7-17/h4-12,15H,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468711 (CHEMBL4286606) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OC)c(OCc3ccccc3)c1)c2=O Show InChI InChI=1S/C25H22O6/c1-27-18-12-22(29-3)24-23(13-18)31-15-19(25(24)26)17-9-10-20(28-2)21(11-17)30-14-16-7-5-4-6-8-16/h4-13,15H,14H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468710 (CHEMBL4281758) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1cccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])c1)c2=O Show InChI InChI=1S/C22H22O5/c1-14(2)8-9-26-16-7-5-6-15(10-16)18-13-27-20-12-17(24-3)11-19(25-4)21(20)22(18)23/h5-8,10-13H,9H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50409930 (CHEMBL2021379) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5+,6-,9-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468708 (CHEMBL4291101) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1ccc(-[#8]-[#6])c(-[#8]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])c1)c2=O Show InChI InChI=1S/C28H32O6/c1-18(2)8-7-9-19(3)12-13-33-24-14-20(10-11-23(24)31-5)22-17-34-26-16-21(30-4)15-25(32-6)27(26)28(22)29/h8,10-12,14-17H,7,9,13H2,1-6H3/b19-12+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144950 (3'-deoxyadenosine | 9-(beta-D-3'-Deoxyribofuranosy...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)C[C@H]1O |r| Show InChI InChI=1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468716 (CHEMBL4289632) Show SMILES COc1cc(OC)c2c(c1)occ(-c1cccc(OCc3ccc(cc3)C(F)(F)F)c1)c2=O Show InChI InChI=1S/C25H19F3O5/c1-30-19-11-21(31-2)23-22(12-19)33-14-20(24(23)29)16-4-3-5-18(10-16)32-13-15-6-8-17(9-7-15)25(26,27)28/h3-12,14H,13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144933 ((2R,3S,4S,5R)-4-Fluoro-5-hydroxymethyl-2-(6-methyl...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](F)[C@H]1O Show InChI InChI=1S/C10H12FN5O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468713 (CHEMBL4293424) Show SMILES COC(=O)c1ccc(COc2cc(ccc2OC)-c2coc3cc(OC)cc(OC)c3c2=O)cc1 Show InChI InChI=1S/C27H24O8/c1-30-19-12-23(32-3)25-24(13-19)35-15-20(26(25)28)18-9-10-21(31-2)22(11-18)34-14-16-5-7-17(8-6-16)27(29)33-4/h5-13,15H,14H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468719 (CHEMBL4278297) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OC)c(OCc3ccc(cc3)[N+]([O-])=O)c1)c2=O Show InChI InChI=1S/C25H21NO8/c1-30-18-11-22(32-3)24-23(12-18)34-14-19(25(24)27)16-6-9-20(31-2)21(10-16)33-13-15-4-7-17(8-5-15)26(28)29/h4-12,14H,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468710 (CHEMBL4281758) Show SMILES [#6]-[#8]-c1cc(-[#8]-[#6])c2c(c1)occ(-c1cccc(-[#8]-[#6]\[#6]=[#6](\[#6])-[#6])c1)c2=O Show InChI InChI=1S/C22H22O5/c1-14(2)8-9-26-16-7-5-6-15(10-16)18-13-27-20-12-17(24-3)11-19(25-4)21(20)22(18)23/h5-8,10-13H,9H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468714 (CHEMBL4282816) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OC)c(OCc3ccc(cc3)C(N)=O)c1)c2=O Show InChI InChI=1S/C26H23NO7/c1-30-18-11-22(32-3)24-23(12-18)34-14-19(25(24)28)17-8-9-20(31-2)21(10-17)33-13-15-4-6-16(7-5-15)26(27)29/h4-12,14H,13H2,1-3H3,(H2,27,29)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Smoothened homolog (Mus musculus)	BDBM50468717 (CHEMBL4286204) Show SMILES COc1cc(OC)c2c(c1)occ(-c1cccc(O)c1)c2=O Show InChI InChI=1S/C17H14O5/c1-20-12-7-14(21-2)16-15(8-12)22-9-13(17(16)19)10-4-3-5-11(18)6-10/h3-9,18H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Antagonist activity at smo in SAG-treated mouse Light2 cells after 48 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468715 (CHEMBL4289866) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OCc3ccccc3)c(OC)c1)c2=O Show InChI InChI=1S/C25H22O6/c1-27-18-12-22(29-3)24-23(13-18)31-15-19(25(24)26)17-9-10-20(21(11-17)28-2)30-14-16-7-5-4-6-8-16/h4-13,15H,14H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144939 ((2R,3R,4R,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2cnc(N)nc12 Show InChI InChI=1S/C11H15N5O4/c1-11(19)7(18)6(3-17)20-9(11)16-4-14-5-2-13-10(12)15-8(5)16/h2,4,6-7,9,17-19H,3H2,1H3,(H2,12,13,15)/t6-,7-,9-,11-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144945 ((2R,3R,4R,5R)-2-Hydroxymethyl-4-methoxy-5-(6-methy...) Show SMILES CO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12 Show InChI InChI=1S/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144936 (CHEMBL1090 | VIDARABINE | adenine arabinoside) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50408410 (CHEMBL480143) Show SMILES C[C@@]1(O)[C@@H](CO)O[C@H]([C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C11H15N5O4/c1-11(19)5(2-17)20-10(7(11)18)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7+,10-,11-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144935 ((2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-3-ethyl-5-...) Show SMILES CC[C@@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H17N5O4/c1-2-12(20)8(19)6(3-18)21-11(12)17-5-16-7-9(13)14-4-15-10(7)17/h4-6,8,11,18-20H,2-3H2,1H3,(H2,13,14,15)/t6-,8-,11-,12-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50422565 (CHEMBL2311161) Show SMILES C[C@]1(O)[C@@H](CO)O[C@H]([C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C11H15N5O4/c1-11(19)5(2-17)20-10(7(11)18)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7+,10-,11+/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144932 ((2R,3R,4R,5R)-4-Fluoro-2-hydroxymethyl-5-(6-methyl...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F Show InChI InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144941 ((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxy...) Show SMILES CO[C@]1(C)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H17N5O4/c1-12(20-2)8(19)6(3-18)21-11(12)17-5-16-7-9(13)14-4-15-10(7)17/h4-6,8,11,18-19H,3H2,1-2H3,(H2,13,14,15)/t6-,8-,11-,12-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144940 ((2R,3S,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES C[C@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12 Show InChI InChI=1S/C11H15N5O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7-,10-,11+/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV NS5B-mediated RNA synthesis				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468720 (CHEMBL4293248) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OCc3ccc(cc3)C(F)(F)F)c(OC)c1)c2=O Show InChI InChI=1S/C26H21F3O6/c1-31-18-11-22(33-3)24-23(12-18)35-14-19(25(24)30)16-6-9-20(21(10-16)32-2)34-13-15-4-7-17(8-5-15)26(27,28)29/h4-12,14H,13H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
Zinc finger protein GLI1 (Mus musculus)	BDBM50468707 (CHEMBL4290935) Show SMILES COc1cc(OC)c2c(c1)occ(-c1ccc(OCc3ccccc3)c(OCc3ccccc3)c1)c2=O Show InChI InChI=1S/C31H26O6/c1-33-24-16-28(34-2)30-29(17-24)37-20-25(31(30)32)23-13-14-26(35-18-21-9-5-3-6-10-21)27(15-23)36-19-22-11-7-4-8-12-22/h3-17,20H,18-19H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza University of Rome Curated by ChEMBL					Assay Description Inhibition of Gli1 transcriptional activity in mouse embroyonic fibroblasts after 24 hrs by renilla luciferase reporter gene assay				Eur J Med Chem 156: 554-562 (2018) Article DOI: 10.1016/j.ejmech.2018.07.017 BindingDB Entry DOI: 10.7270/Q2HD7ZB4
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144932 ((2R,3R,4R,5R)-4-Fluoro-2-hydroxymethyl-5-(6-methyl...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F Show InChI InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144930 (2-Amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-hydr...) Show SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1F Show InChI InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4-,6-,9-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144933 ((2R,3S,4S,5R)-4-Fluoro-5-hydroxymethyl-2-(6-methyl...) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](F)[C@H]1O Show InChI InChI=1S/C10H12FN5O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144936 (CHEMBL1090 | VIDARABINE | adenine arabinoside) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144940 ((2R,3S,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...) Show SMILES C[C@]1(O)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12 Show InChI InChI=1S/C11H15N5O4/c1-11(19)7(18)5(2-17)20-10(11)16-4-15-6-8(12)13-3-14-9(6)16/h3-5,7,10,17-19H,2H2,1H3,(H2,12,13,14)/t5-,7-,10-,11+/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50144941 ((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxy...) Show SMILES CO[C@]1(C)[C@H](O)[C@@H](CO)O[C@H]1n1cnc2c(N)ncnc12 Show InChI InChI=1S/C12H17N5O4/c1-12(20-2)8(19)6(3-18)21-11(12)17-5-16-7-9(13)14-4-15-10(7)17/h4-6,8,11,18-19H,3H2,1-2H3,(H2,13,14,15)/t6-,8-,11-,12-/m1/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Isis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition HCV RNA replication				J Med Chem 47: 2283-95 (2004) Article DOI: 10.1021/jm030424e BindingDB Entry DOI: 10.7270/Q2QZ2BQ3
					More data for this Ligand-Target Pair

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