Compile Data Set for Download or QSAR

Found 223 hits with Last Name = 'miknyoczki' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of adenosine A2A receptor				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of muscarinic M4 receptor				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236260 (7-[(1E)-1-(hydroxyimino)ethyl]-19-methyl-3,13,19,2...) Show SMILES CC(N=O)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C22H19N5O2/c1-10(26-29)11-3-5-16-13(7-11)19-14-8-23-22(28)20(14)18-12(21(19)24-16)4-6-17-15(18)9-27(2)25-17/h3,5,7,9-10,24H,4,6,8H2,1-2H3,(H,23,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236266 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3,13,19,2...) Show SMILES CO\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C23H21N5O2/c1-11(27-30-3)12-4-6-17-14(8-12)20-15-9-24-23(29)21(15)19-13(22(20)25-17)5-7-18-16(19)10-28(2)26-18/h4,6,8,10,25H,5,7,9H2,1-3H3,(H,24,29)/b27-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236262 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-propyl-...) Show SMILES CCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(\C)=N\OC Show InChI InChI=1S/C26H27N5O2/c1-5-10-31-21-9-6-15(14(2)29-33-4)11-17(21)23-18-12-27-26(32)24(18)22-16(25(23)31)7-8-20-19(22)13-30(3)28-20/h6,9,11,13H,5,7-8,10,12H2,1-4H3,(H,27,32)/b29-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236262 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-propyl-...) Show SMILES CCCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(\C)=N\OC Show InChI InChI=1S/C26H27N5O2/c1-5-10-31-21-9-6-15(14(2)29-33-4)11-17(21)23-18-12-27-26(32)24(18)22-16(25(23)31)7-8-20-19(22)13-30(3)28-20/h6,9,11,13H,5,7-8,10,12H2,1-4H3,(H,27,32)/b29-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50236270 (1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...) Show SMILES COc1ccc(cc1)-c1oc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2c(F)cccc2C(F)(F)F)cc1 Show InChI InChI=1S/C27H19F4N5O3/c1-38-17-11-7-15(8-12-17)23-20(21-24(32)33-13-34-25(21)39-23)14-5-9-16(10-6-14)35-26(37)36-22-18(27(29,30)31)3-2-4-19(22)28/h2-13H,1H3,(H2,32,33,34)(H2,35,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236246 (7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3,13,19,20...) Show SMILES CCO\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C24H23N5O2/c1-4-31-28-12(2)13-5-7-18-15(9-13)21-16-10-25-24(30)22(16)20-14(23(21)26-18)6-8-19-17(20)11-29(3)27-19/h5,7,9,11,26H,4,6,8,10H2,1-3H3,(H,25,30)/b28-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236263 (19-methyl-7-[(1E)-1-[(2-methylpropoxy)imino]ethyl]...) Show SMILES CC(C)CO\N=C(/C)c1ccc2n(C(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C29H33N5O2/c1-15(2)14-36-32-17(5)18-7-10-24-20(11-18)26-21-12-30-29(35)27(21)25-19(28(26)34(24)16(3)4)8-9-23-22(25)13-33(6)31-23/h7,10-11,13,15-16H,8-9,12,14H2,1-6H3,(H,30,35)/b32-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human VEGFR1 using ATP as substrate				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236264 (19-methyl-7-[(1E)-1-[(propan-2-yloxy)imino]ethyl]-...) Show SMILES CC(C)O\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C25H25N5O2/c1-12(2)32-29-13(3)14-5-7-19-16(9-14)22-17-10-26-25(31)23(17)21-15(24(22)27-19)6-8-20-18(21)11-30(4)28-20/h5,7,9,11-12,27H,6,8,10H2,1-4H3,(H,26,31)/b29-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human TRK-A using ATP as substrate				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50379196 (CHEMBL2010870) Show SMILES CC(C)n1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C27H25N7O/c1-14(2)34-21-8-5-15(31-27-28-9-4-10-29-27)11-17(21)23-18-12-30-26(35)24(18)22-16(25(23)34)6-7-20-19(22)13-33(3)32-20/h4-5,8-11,13-14H,6-7,12H2,1-3H3,(H,30,35)(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236259 (3-ethyl-19-methyl-7-[(1E)-1-[(2-methylpropoxy)imin...) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(\C)=N\OCC(C)C Show InChI InChI=1S/C28H31N5O2/c1-6-33-23-10-7-17(16(4)31-35-14-15(2)3)11-19(23)25-20-12-29-28(34)26(20)24-18(27(25)33)8-9-22-21(24)13-32(5)30-22/h7,10-11,13,15H,6,8-9,12,14H2,1-5H3,(H,29,34)/b31-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236270 (1-(4-(4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...) Show SMILES COc1ccc(cc1)-c1oc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2c(F)cccc2C(F)(F)F)cc1 Show InChI InChI=1S/C27H19F4N5O3/c1-38-17-11-7-15(8-12-17)23-20(21-24(32)33-13-34-25(21)39-23)14-5-9-16(10-6-14)35-26(37)36-22-18(27(29,30)31)3-2-4-19(22)28/h2-13H,1H3,(H2,32,33,34)(H2,35,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236268 (7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3-(2-methy...) Show SMILES CCO\N=C(/C)c1ccc2n(CC(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C28H31N5O2/c1-6-35-31-16(4)17-7-10-23-19(11-17)25-20-12-29-28(34)26(20)24-18(27(25)33(23)13-15(2)3)8-9-22-21(24)14-32(5)30-22/h7,10-11,14-15H,6,8-9,12-13H2,1-5H3,(H,29,34)/b31-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236257 (19-methyl-3-(2-methylpropyl)-7-[(1E)-1-[(propan-2-...) Show SMILES CC(C)Cn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(\C)=N\OC(C)C Show InChI InChI=1S/C29H33N5O2/c1-15(2)13-34-24-10-7-18(17(5)32-36-16(3)4)11-20(24)26-21-12-30-29(35)27(21)25-19(28(26)34)8-9-23-22(25)14-33(6)31-23/h7,10-11,14-16H,8-9,12-13H2,1-6H3,(H,30,35)/b32-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236251 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-(2-meth...) Show SMILES CO\N=C(/C)c1ccc2n(CC(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C27H29N5O2/c1-14(2)12-32-22-9-6-16(15(3)30-34-5)10-18(22)24-19-11-28-27(33)25(19)23-17(26(24)32)7-8-21-20(23)13-31(4)29-21/h6,9-10,13-14H,7-8,11-12H2,1-5H3,(H,28,33)/b30-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236269 (19-methyl-3-(propan-2-yl)-7-[(1E)-1-[(propan-2-ylo...) Show SMILES CC(C)O\N=C(/C)c1ccc2n(C(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C28H31N5O2/c1-14(2)33-23-10-7-17(16(5)31-35-15(3)4)11-19(23)25-20-12-29-28(34)26(20)24-18(27(25)33)8-9-22-21(24)13-32(6)30-22/h7,10-11,13-15H,8-9,12H2,1-6H3,(H,29,34)/b31-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236254 (7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3-(propan-...) Show SMILES CCO\N=C(/C)c1ccc2n(C(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C27H29N5O2/c1-6-34-30-15(4)16-7-10-22-18(11-16)24-19-12-28-27(33)25(19)23-17(26(24)32(22)14(2)3)8-9-21-20(23)13-31(5)29-21/h7,10-11,13-14H,6,8-9,12H2,1-5H3,(H,28,33)/b30-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236248 (7-[(1E)-(ethoxyimino)methyl]-19-methyl-3,13,19,20-...) Show SMILES CCO\N=C\c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C23H21N5O2/c1-3-30-25-9-12-4-6-17-14(8-12)20-15-10-24-23(29)21(15)19-13(22(20)26-17)5-7-18-16(19)11-28(2)27-18/h4,6,8-9,11,26H,3,5,7,10H2,1-2H3,(H,24,29)/b25-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236252 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-(propan...) Show SMILES CO\N=C(/C)c1ccc2n(C(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C26H27N5O2/c1-13(2)31-21-9-6-15(14(3)29-33-5)10-17(21)23-18-11-27-26(32)24(18)22-16(25(23)31)7-8-20-19(22)12-30(4)28-20/h6,9-10,12-13H,7-8,11H2,1-5H3,(H,27,32)/b29-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236258 (19-methyl-7-[(1E)-1-[(2-methylpropoxy)imino]ethyl]...) Show SMILES CC(C)CO\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C26H27N5O2/c1-13(2)12-33-30-14(3)15-5-7-20-17(9-15)23-18-10-27-26(32)24(18)22-16(25(23)28-20)6-8-21-19(22)11-31(4)29-21/h5,7,9,11,13,28H,6,8,10,12H2,1-4H3,(H,27,32)/b30-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236256 (3-ethyl-7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3...) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(\C)=N\OC Show InChI InChI=1S/C25H25N5O2/c1-5-30-20-9-6-14(13(2)28-32-4)10-16(20)22-17-11-26-25(31)23(17)21-15(24(22)30)7-8-19-18(21)12-29(3)27-19/h6,9-10,12H,5,7-8,11H2,1-4H3,(H,26,31)/b28-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236254 (7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3-(propan-...) Show SMILES CCO\N=C(/C)c1ccc2n(C(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C27H29N5O2/c1-6-34-30-15(4)16-7-10-22-18(11-16)24-19-12-28-27(33)25(19)23-17(26(24)32(22)14(2)3)8-9-21-20(23)13-31(5)29-21/h7,10-11,13-14H,6,8-9,12H2,1-5H3,(H,28,33)/b30-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236264 (19-methyl-7-[(1E)-1-[(propan-2-yloxy)imino]ethyl]-...) Show SMILES CC(C)O\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C25H25N5O2/c1-12(2)32-29-13(3)14-5-7-19-16(9-14)22-17-10-26-25(31)23(17)21-15(24(22)27-19)6-8-20-18(21)11-30(4)28-20/h5,7,9,11-12,27H,6,8,10H2,1-4H3,(H,26,31)/b29-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236267 (7-[(1E)-1-(methoxyimino)-2-methylpropyl]-19-methyl...) Show SMILES CO\N=C(/C(C)C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C25H25N5O2/c1-12(2)23(29-32-4)13-5-7-18-15(9-13)21-16-10-26-25(31)22(16)20-14(24(21)27-18)6-8-19-17(20)11-30(3)28-19/h5,7,9,11-12,27H,6,8,10H2,1-4H3,(H,26,31)/b29-23+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236246 (7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3,13,19,20...) Show SMILES CCO\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C24H23N5O2/c1-4-31-28-12(2)13-5-7-18-15(9-13)21-16-10-25-24(30)22(16)20-14(23(21)26-18)6-8-19-17(20)11-29(3)27-19/h5,7,9,11,26H,4,6,8,10H2,1-3H3,(H,25,30)/b28-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGF-stimulated VEGFR2 autophosphorylation in HUVEC cells at 50 nM relative to control				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236268 (7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3-(2-methy...) Show SMILES CCO\N=C(/C)c1ccc2n(CC(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C28H31N5O2/c1-6-35-31-16(4)17-7-10-23-19(11-17)25-20-12-29-28(34)26(20)24-18(27(25)33(23)13-15(2)3)8-9-22-21(24)14-32(5)30-22/h7,10-11,14-15H,6,8-9,12-13H2,1-5H3,(H,29,34)/b31-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50379195 (CHEMBL2010869) Show SMILES CCCn1c2ccc(Nc3ncc(CC)cn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C29H29N7O/c1-4-10-36-23-9-6-17(33-29-31-12-16(5-2)13-32-29)11-19(23)25-20-14-30-28(37)26(20)24-18(27(25)36)7-8-22-21(24)15-35(3)34-22/h6,9,11-13,15H,4-5,7-8,10,14H2,1-3H3,(H,30,37)(H,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human RET using ATP as substrate				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236253 (7-[(1E)-1-(methoxyimino)ethyl]-3,19-dimethyl-3,13,...) Show SMILES CO\N=C(/C)c1ccc2n(C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C24H23N5O2/c1-12(27-31-4)13-5-8-19-15(9-13)21-16-10-25-24(30)22(16)20-14(23(21)29(19)3)6-7-18-17(20)11-28(2)26-18/h5,8-9,11H,6-7,10H2,1-4H3,(H,25,30)/b27-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human TRK-B using ATP as substrate				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50379193 (CHEMBL2010871) Show SMILES CCCn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C27H25N7O/c1-3-11-34-21-8-5-15(31-27-28-9-4-10-29-27)12-17(21)23-18-13-30-26(35)24(18)22-16(25(23)34)6-7-20-19(22)14-33(2)32-20/h4-5,8-10,12,14H,3,6-7,11,13H2,1-2H3,(H,30,35)(H,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236251 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-(2-meth...) Show SMILES CO\N=C(/C)c1ccc2n(CC(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C27H29N5O2/c1-14(2)12-32-22-9-6-16(15(3)30-34-5)10-18(22)24-19-11-28-27(33)25(19)23-17(26(24)32)7-8-21-20(23)13-31(4)29-21/h6,9-10,13-14H,7-8,11-12H2,1-5H3,(H,28,33)/b30-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50361566 (CHEMBL1939493) Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)[C@@H](CC3(C)C)NC(=O)OC)c2)ncc1Cl |r| Show InChI InChI=1S/C26H27ClFN7O4/c1-26(2)11-19(33-25(38)39-4)23(37)32-18-10-13(8-9-15(18)26)31-24-30-12-16(27)21(35-24)34-20-14(22(36)29-3)6-5-7-17(20)28/h5-10,12,19H,11H2,1-4H3,(H,29,36)(H,32,37)(H,33,38)(H2,30,31,34,35)/t19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay				Bioorg Med Chem 19: 6274-84 (2011) Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50236251 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-(2-meth...) Show SMILES CO\N=C(/C)c1ccc2n(CC(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C27H29N5O2/c1-14(2)12-32-22-9-6-16(15(3)30-34-5)10-18(22)24-19-11-28-27(33)25(19)23-17(26(24)32)7-8-21-20(23)13-31(4)29-21/h6,9-10,13-14H,7-8,11-12H2,1-5H3,(H,28,33)/b30-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Blk (Mus musculus)	BDBM50379186 (CEP-11981 | CHEMBL2010872) Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C28H27N7O/c1-15(2)13-35-22-8-5-16(32-28-29-9-4-10-30-28)11-18(22)24-19-12-31-27(36)25(19)23-17(26(24)35)6-7-21-20(23)14-34(3)33-21/h4-5,8-11,14-15H,6-7,12-13H2,1-3H3,(H,31,36)(H,29,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of mouse BLK using ATP as substrate				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50333561 (2-{5-Chloro-2-[3-(2-methoxy-ethyl)-2,3,4,5-tetrahy...) Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3CCN(CCOC)CCc3c2)ncc1Cl Show InChI InChI=1S/C25H28ClFN6O2/c1-28-24(34)19-4-3-5-21(27)22(19)31-23-20(26)15-29-25(32-23)30-18-7-6-16-8-10-33(12-13-35-2)11-9-17(16)14-18/h3-7,14-15H,8-13H2,1-2H3,(H,28,34)(H2,29,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of c-Met cytoplasmic domain expressed in baculovirus after 30 mins by time-resolved fluorescence assay				Bioorg Med Chem Lett 21: 660-3 (2011) Article DOI: 10.1016/j.bmcl.2010.12.013 BindingDB Entry DOI: 10.7270/Q2RB74WV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50379195 (CHEMBL2010869) Show SMILES CCCn1c2ccc(Nc3ncc(CC)cn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C29H29N7O/c1-4-10-36-23-9-6-17(33-29-31-12-16(5-2)13-32-29)11-19(23)25-20-14-30-28(37)26(20)24-18(27(25)36)7-8-22-21(24)15-35(3)34-22/h6,9,11-13,15H,4-5,7-8,10,14H2,1-3H3,(H,30,37)(H,31,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50334085 (2-[5-Chloro-2-(1-ethyl-5,5-dimethyl-2-oxo-2,3,4,5-...) Show SMILES CCN1c2cc(Nc3ncc(Cl)c(Nc4c(F)cccc4C(=O)NC)n3)ccc2C(C)(C)CCC1=O Show InChI InChI=1S/C26H28ClFN6O2/c1-5-34-20-13-15(9-10-17(20)26(2,3)12-11-21(34)35)31-25-30-14-18(27)23(33-25)32-22-16(24(36)29-4)7-6-8-19(22)28/h6-10,13-14H,5,11-12H2,1-4H3,(H,29,36)(H2,30,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of GST-tagged c-Met expressed in baculovirus system using phospholipase C-gamma as substrate after 30 mins by time-resolved fluorescence a...				Bioorg Med Chem 19: 6274-84 (2011) Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50334084 (2-[5-Chloro-2-(5,5-dimethyl-2-oxo-2,3,4,5-tetrahyd...) Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)CCC3(C)C)c2)ncc1Cl Show InChI InChI=1S/C24H24ClFN6O2/c1-24(2)10-9-19(33)30-18-11-13(7-8-15(18)24)29-23-28-12-16(25)21(32-23)31-20-14(22(34)27-3)5-4-6-17(20)26/h4-8,11-12H,9-10H2,1-3H3,(H,27,34)(H,30,33)(H2,28,29,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay				Bioorg Med Chem 19: 6274-84 (2011) Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50236258 (19-methyl-7-[(1E)-1-[(2-methylpropoxy)imino]ethyl]...) Show SMILES CC(C)CO\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C26H27N5O2/c1-13(2)12-33-30-14(3)15-5-7-20-17(9-15)23-18-10-27-26(32)24(18)22-16(25(23)28-20)6-8-21-19(22)11-31(4)29-21/h5,7,9,11,13,28H,6,8,10,12H2,1-4H3,(H,27,32)/b30-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50236251 (7-[(1E)-1-(methoxyimino)ethyl]-19-methyl-3-(2-meth...) Show SMILES CO\N=C(/C)c1ccc2n(CC(C)C)c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C27H29N5O2/c1-14(2)12-32-22-9-6-16(15(3)30-34-5)10-18(22)24-19-11-28-27(33)25(19)23-17(26(24)32)7-8-21-20(23)13-31(4)29-21/h6,9-10,13-14H,7-8,11-12H2,1-5H3,(H,28,33)/b30-15+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR3				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50379192 (CHEMBL2010877) Show SMILES CC(C)n1c2ccc(Nc3cccnn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12 Show InChI InChI=1S/C27H25N7O/c1-14(2)34-21-9-6-15(30-22-5-4-10-29-31-22)11-17(21)24-18-12-28-27(35)25(18)23-16(26(24)34)7-8-20-19(23)13-33(3)32-20/h4-6,9-11,13-14H,7-8,12H2,1-3H3,(H,28,35)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGF-R2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluore...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50379194 (CHEMBL2010873) Show SMILES CCc1cnc(Nc2ccc3n(CC(C)C)c4c5CCc6nn(C)cc6-c5c5C(=O)NCc5c4c3c2)nc1 Show InChI InChI=1S/C30H31N7O/c1-5-17-11-32-30(33-12-17)34-18-6-9-24-20(10-18)26-21-13-31-29(38)27(21)25-19(28(26)37(24)14-16(2)3)7-8-23-22(25)15-36(4)35-23/h6,9-12,15-16H,5,7-8,13-14H2,1-4H3,(H,31,38)(H,32,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...				J Med Chem 55: 903-13 (2012) Article DOI: 10.1021/jm201449n BindingDB Entry DOI: 10.7270/Q2ZS2XHW
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50236258 (19-methyl-7-[(1E)-1-[(2-methylpropoxy)imino]ethyl]...) Show SMILES CC(C)CO\N=C(/C)c1ccc2[nH]c3c4CCc5nn(C)cc5-c4c4C(=O)NCc4c3c2c1 Show InChI InChI=1S/C26H27N5O2/c1-13(2)12-33-30-14(3)15-5-7-20-17(9-15)23-18-10-27-26(32)24(18)22-16(25(23)28-20)6-8-21-19(22)11-31(4)29-21/h5,7,9,11,13,28H,6,8,10,12H2,1-4H3,(H,27,32)/b30-14+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant TIE2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50361570 (CHEMBL1939481) Show SMILES CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(NC(=O)C(CC3(C)C)NC(=O)CN(C)C)c2)ncc1Cl Show InChI InChI=1S/C28H32ClFN8O3/c1-28(2)12-21(34-22(39)14-38(4)5)26(41)35-20-11-15(9-10-17(20)28)33-27-32-13-18(29)24(37-27)36-23-16(25(40)31-3)7-6-8-19(23)30/h6-11,13,21H,12,14H2,1-5H3,(H,31,40)(H,34,39)(H,35,41)(H2,32,33,36,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of c-Met phosphorylation in human GTL16 cells after 2 hrs by immunoassay				Bioorg Med Chem 19: 6274-84 (2011) Article DOI: 10.1016/j.bmc.2011.09.006 BindingDB Entry DOI: 10.7270/Q24M950J
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM25115 (3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...) Show SMILES NC(=O)c1c(NC(=O)NCCCCN2CCCC2)snc1OCc1c(F)cc(Br)cc1F Show InChI InChI=1S/C20H24BrF2N5O3S/c21-12-9-14(22)13(15(23)10-12)11-31-18-16(17(24)29)19(32-27-18)26-20(30)25-5-1-2-6-28-7-3-4-8-28/h9-10H,1-8,11H2,(H2,24,29)(H2,25,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR2 by HTRF assay				Bioorg Med Chem Lett 18: 1916-21 (2008) Article DOI: 10.1016/j.bmcl.2008.02.001 BindingDB Entry DOI: 10.7270/Q27M07PV
					More data for this Ligand-Target Pair

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