Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human)) | BDBM22202 (S1P | [32P]S1P | [33P]S1P | sphingosine-1-phosphat...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 0.920 | -47.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM22202 (S1P | [32P]S1P | [33P]S1P | sphingosine-1-phosphat...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.20 | -47.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM23165 (CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.10 | -46.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human)) | BDBM23165 (CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 2.20 | -45.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human)) | BDBM22202 (S1P | [32P]S1P | [33P]S1P | sphingosine-1-phosphat...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 2.70 | -45.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088846 (CHEMBL353678 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-e...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human)) | BDBM22202 (S1P | [32P]S1P | [33P]S1P | sphingosine-1-phosphat...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 3.40 | -44.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088844 (4-{4-[4-(4-Phenyl-piperazin-1-yl)-butyl]-phenyl}-t...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM23163 (CHEMBL114606 | FTY720-phosphate, rac-2 | {2-amino-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.10 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human)) | BDBM23163 (CHEMBL114606 | FTY720-phosphate, rac-2 | {2-amino-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.20 | -44.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088839 (CHEMBL169702 | N-{4-[4-(4-Phenyl-piperazin-1-yl)-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human trypsin. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM22202 (S1P | [32P]S1P | [33P]S1P | sphingosine-1-phosphat...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 5.40 | -43.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (BOVINE) | BDBM50088844 (4-{4-[4-(4-Phenyl-piperazin-1-yl)-butyl]-phenyl}-t...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards Dopamine receptor D2 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM23165 (CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 5.90 | -43.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088839 (CHEMBL169702 | N-{4-[4-(4-Phenyl-piperazin-1-yl)-b...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088841 (CHEMBL352617 | N-{4-[3-(4-Phenyl-piperazin-1-yl)-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088844 (4-{4-[4-(4-Phenyl-piperazin-1-yl)-butyl]-phenyl}-t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM23163 (CHEMBL114606 | FTY720-phosphate, rac-2 | {2-amino-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 13 | -41.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human)) | BDBM23165 (CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | 23 | -40.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088841 (CHEMBL352617 | N-{4-[3-(4-Phenyl-piperazin-1-yl)-p...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human)) | BDBM23163 (CHEMBL114606 | FTY720-phosphate, rac-2 | {2-amino-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 37 | -39.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM50088844 (4-{4-[4-(4-Phenyl-piperazin-1-yl)-butyl]-phenyl}-t...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibition of GC1 extended spectrum class C beta-lactamase | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM50088839 (CHEMBL169702 | N-{4-[4-(4-Phenyl-piperazin-1-yl)-b...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibition of GC1 extended spectrum class C beta-lactamase | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (BOVINE) | BDBM50088839 (CHEMBL169702 | N-{4-[4-(4-Phenyl-piperazin-1-yl)-b...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards Dopamine receptor D2 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088846 (CHEMBL353678 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human trypsin. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human)) | BDBM23164 (CHEMBL190006 | FTY720-phosphate, (R)-2 | [(2R)-2-a...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 105 | -37.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 5 (Homo sapiens (Human)) | BDBM23164 (CHEMBL190006 | FTY720-phosphate, (R)-2 | [(2R)-2-a...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 121 | -36.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM50088846 (CHEMBL353678 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-e...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088845 (CHEMBL170307 | N-[4-(4-Phenyl-piperazin-1-ylmethyl...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM50088841 (CHEMBL352617 | N-{4-[3-(4-Phenyl-piperazin-1-yl)-p...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibition of GC1 extended spectrum class C beta-lactamase | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (BOVINE) | BDBM50088846 (CHEMBL353678 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-e...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards Dopamine receptor D2 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM23164 (CHEMBL190006 | FTY720-phosphate, (R)-2 | [(2R)-2-a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 277 | -34.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (BOVINE) | BDBM50088841 (CHEMBL352617 | N-{4-[3-(4-Phenyl-piperazin-1-yl)-p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards Dopamine receptor D2 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human)) | BDBM23164 (CHEMBL190006 | FTY720-phosphate, (R)-2 | [(2R)-2-a...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 586 | -33.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088843 (CHEMBL171115 | N-{4-[4-(4-Methoxy-phenyl)-piperazi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (BOVINE) | BDBM50088843 (CHEMBL171115 | N-{4-[4-(4-Methoxy-phenyl)-piperazi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards Dopamine receptor D2 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088847 (CHEMBL171345 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088842 (CHEMBL171052 | N-{4-[4-(4-Fluoro-phenyl)-piperazin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088847 (CHEMBL171345 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088843 (CHEMBL171115 | N-{4-[4-(4-Methoxy-phenyl)-piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards Alpha-1 adrenergic receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM50088843 (CHEMBL171115 | N-{4-[4-(4-Methoxy-phenyl)-piperazi...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM50088840 (CHEMBL352576 | N-{4-[4-(2,4-Difluoro-phenyl)-piper...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human thrombin. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088845 (CHEMBL170307 | N-[4-(4-Phenyl-piperazin-1-ylmethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human plasmin. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50088842 (CHEMBL171052 | N-{4-[4-(4-Fluoro-phenyl)-piperazin...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of human Coagulation factor X. | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (BOVINE) | BDBM50088842 (CHEMBL171052 | N-{4-[4-(4-Fluoro-phenyl)-piperazin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards Dopamine receptor D2 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50088840 (CHEMBL352576 | N-{4-[4-(2,4-Difluoro-phenyl)-piper...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human)) | BDBM23165 (CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-a...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | >1.00E+3 | >-31.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Homo sapiens (Human)) | BDBM50088847 (CHEMBL171345 | N-{4-[4-(4-Chloro-phenyl)-piperazin...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, Ltd. Curated by ChEMBL | Assay Description Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99 | Bioorg Med Chem Lett 10: 875-9 (2000) BindingDB Entry DOI: 10.7270/Q2CZ36C7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human)) | BDBM23164 (CHEMBL190006 | FTY720-phosphate, (R)-2 | [(2R)-2-a...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | >1.00E+3 | >-31.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sphingosine 1-phosphate receptor 2 (Homo sapiens (Human)) | BDBM23163 (CHEMBL114606 | FTY720-phosphate, rac-2 | {2-amino-...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+3 | >-31.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 4 |
Mitsubishi Pharma Corporation | Assay Description Ki Values were determined by competition of [32P]-S1P binding to stably transfected CHO (S1P1,2,4) or RH7777 (S1P3,5) cells expressing the indicated ... | Bioorg Med Chem 13: 425-32 (2005) Article DOI: 10.1016/j.bmc.2004.10.008 BindingDB Entry DOI: 10.7270/Q257199Q | |||||||||||
More data for this Ligand-Target Pair |
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