Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50083552 (1,9-di{4-[5-amino(imino)methylbenzo[b]furan-2-ylca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL | Assay Description Inhibition of tryptase activity | Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50083561 (1-{4-[5-amino(imino)methylbenzo[b]thiophen-2-ylcar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 0.0280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL | Assay Description Inhibition of tryptase activity | Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50083556 (1-{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 0.0290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL | Assay Description Inhibition of tryptase activity | Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50083541 (1-{4-[5-amino(imino)methyl-4,5,6,7-tetrahydrothien...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL | Assay Description Inhibition of tryptase activity | Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50083548 (1-{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.0570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL | Assay Description Inhibition of tryptase activity | Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50217306 (CHEMBL112049) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL | Assay Description Inhibition of tryptase activity | Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201292 (7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201292 (7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201280 (CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.660 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50165019 (4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50165019 (4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tryptase beta-2/delta/gamma (Homo sapiens (Human)) | BDBM50083549 (1-{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL | Assay Description Inhibition of tryptase activity | Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098853 (2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 1.12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description Inhibitory activity against canine skin chymase | J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201280 (CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201277 ((4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50201292 (7,8-dichloro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyr...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201296 (4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201285 (3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201277 ((4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201294 (3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201283 (3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098874 (4-{2-[5-Amino-2-(3-chloro-phenyl)-6-oxo-6H-pyrimid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 2.62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201285 (3-((2-cycloheptylethylamino)methyl)-N,N-dimethyl-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201296 (4-(2-((3-(dimethylamino)-3,4-dihydro-2H-benzo[b][1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201294 (3-((2-cyclopentylethylamino)methyl)-N,N-dimethyl-3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098868 (4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098847 (2-(2-{2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description Inhibitory activity against canine skin chymase | J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201299 (7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098853 (2-(2-{2-[5-Amino-2-(3-methoxy-phenyl)-6-oxo-6H-pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 4.85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description Inhibitory activity evaluated against chymase from human heart. | J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201284 (3-((cyclohexylmethylamino)methyl)-N,N-dimethyl-3,4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201299 (7-fluoro-N,N-dimethyl-3-((2-(tetrahydro-2H-pyran-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098854 (2-{2-[2-(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description Inhibitory activity evaluated against chymase from human heart. | J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098841 (2-(2-{2-[5-Amino-2-(3-amino-phenyl)-6-oxo-6H-pyrim...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description Inhibitory activity evaluated against chymase from human heart. | J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50068894 (3-(4-{[(S)-1-((S)-2-tert-Butoxycarbonylamino-3-met...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201276 (3-((2-(3,6-dihydro-2H-thiopyran-4-yl)ethylamino)me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human)) | BDBM50201280 (CHEMBL394137 | {3-[(2-adamantan-1-yl-ethylamino)-m...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M1 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201287 (CHEMBL435353 | N,N-dimethyl-3-((2-(tetrahydro-2H-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201283 (3-((2-cyclohexylethylamino)methyl)-N,N-dimethyl-3,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201286 (CHEMBL233201 | N,N-dimethyl-3-((2-(tetrahydro-2H-t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201286 (CHEMBL233201 | N,N-dimethyl-3-((2-(tetrahydro-2H-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098892 (4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50165019 (4-(Diethylamino)-2-butynyl alpha-phenylcyclohexane...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human)) | BDBM50201291 (CHEMBL394255 | N,N-dimethyl-3-((2-(tetrahydropyran...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M2 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098879 (4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymotrypsin-C (Homo sapiens (Human)) | BDBM87059 (CHEMBL247767 | Chymostatin) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against bovine pancreas chymotrypsin | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymotrypsin-C (Homo sapiens (Human)) | BDBM87059 (CHEMBL247767 | Chymostatin) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description inhibitory activity against alpha chymotrypsin from bovine pancreas. | J Med Chem 44: 1286-96 (2001) BindingDB Entry DOI: 10.7270/Q26H4J4K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098880 (3-{4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098870 (CHEMBL26182 | {4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-py...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50098878 (4-[2-(5-Amino-6-oxo-2-m-tolyl-6H-pyrimidin-1-yl)-a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Welfide Corporation Curated by ChEMBL | Assay Description In vitro inhibitory activity was determined against human heart chymase | J Med Chem 44: 1297-304 (2001) BindingDB Entry DOI: 10.7270/Q22R3SCD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human)) | BDBM50201287 (CHEMBL435353 | N,N-dimethyl-3-((2-(tetrahydro-2H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Pharma Corporation Curated by ChEMBL | Assay Description Displacement of 1-[N-methyl- 3H]scopolamine from human muscarinic M3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 925-31 (2007) Article DOI: 10.1016/j.bmcl.2006.11.058 BindingDB Entry DOI: 10.7270/Q2DB81HZ | |||||||||||
More data for this Ligand-Target Pair |
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