Compile Data Set for Download or QSAR

Found 127 hits with Last Name = 'andreola' and Initial = 'ml'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029662 (3-Amino-4-(3,5-dimethyl-phenylsulfanyl)-5-ethyl-6-...) Show SMILES CCc1c(C)[nH]c(=O)c(N)c1Sc1cc(C)cc(C)c1 Show InChI InChI=1S/C16H20N2OS/c1-5-13-11(4)18-16(19)14(17)15(13)20-12-7-9(2)6-10(3)8-12/h6-8H,5,17H2,1-4H3,(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM25351 (N-[2-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydr...) Show SMILES Cc1nnc(o1)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C Show InChI InChI=1S/C20H21FN6O5/c1-10-25-26-17(32-10)16(30)24-20(2,3)19-23-13(14(28)18(31)27(19)4)15(29)22-9-11-5-7-12(21)8-6-11/h5-8,28H,9H2,1-4H3,(H,22,29)(H,24,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	DrugBank Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10908 (3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5...) Show SMILES CCc1c(C)[nH]c(=O)c(N(C)C)c1Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C19H26N2O/c1-7-16-14(4)20-19(22)18(21(5)6)17(16)11-15-9-12(2)8-13(3)10-15/h8-10H,7,11H2,1-6H3,(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10903 (4-[(3,5-dimethylphenyl)sulfanyl]-5-ethyl-6-methyl-...) Show SMILES CCc1c(C)[nH]c(=O)c(c1Sc1cc(C)cc(C)c1)[N+]([O-])=O Show InChI InChI=1S/C16H18N2O3S/c1-5-13-11(4)17-16(19)14(18(20)21)15(13)22-12-7-9(2)6-10(3)8-12/h6-8H,5H2,1-4H3,(H,17,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029665 (4-(3,5-Dimethyl-phenylsulfanyl)-5-ethyl-6-methyl-3...) Show SMILES CCc1c(C)[n-]c(=[OH+])c(c1Sc1cc(C)cc(C)c1)[N+]([O-])=O Show InChI InChI=1S/C16H18N2O3S/c1-5-13-11(4)17-16(19)14(18(20)21)15(13)22-12-7-9(2)6-10(3)8-12/h6-8H,5H2,1-4H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) Show SMILES FC(F)(F)[C@]1(OC(=O)Nc2ccc(Cl)cc12)C#CC1CC1 |r| Show InChI InChI=1S/C14H9ClF3NO2/c15-9-3-4-11-10(7-9)13(14(16,17)18,21-12(20)19-11)6-5-8-1-2-8/h3-4,7-8H,1-2H2,(H,19,20)/t13-/m0/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Integrase (Human immunodeficiency virus 1)	BDBM50587990 (CHEMBL5182942) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3cccc(Cl)c3Cl)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10906 (3-Amino-4-(3,5-dimethylbenzoyl)-5-ethyl-6-methylpy...) Show SMILES CCc1c(C)[nH]c(=O)c(N)c1C(=O)c1cc(C)cc(C)c1 Show InChI InChI=1S/C17H20N2O2/c1-5-13-11(4)19-17(21)15(18)14(13)16(20)12-7-9(2)6-10(3)8-12/h6-8H,5,18H2,1-4H3,(H,19,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10905 (3-Amino-4-(3,5-dimethylbenzyl)-5-ethyl-6-methylpyr...) Show SMILES CCc1c(C)[nH]c(=O)c(N)c1Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C17H22N2O/c1-5-14-12(4)19-17(20)16(18)15(14)9-13-7-10(2)6-11(3)8-13/h6-8H,5,9,18H2,1-4H3,(H,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029660 (3-Amino-4-(3,5-dimethyl-phenylsulfanyl)-5-methyl-1...) Show SMILES Cc1cc(C)cc(Sc2c(C)c[nH]c(=O)c2N)c1 Show InChI InChI=1S/C14H16N2OS/c1-8-4-9(2)6-11(5-8)18-13-10(3)7-16-14(17)12(13)15/h4-7H,15H2,1-3H3,(H,16,17)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM33411 (β-Thujaplicinol | hydroxytropolone, 3) Show SMILES CC(C)c1ccc(O)c(=O)c(O)c1 Show InChI InChI=1S/C10H12O3/c1-6(2)7-3-4-8(11)10(13)9(12)5-7/h3-6H,1-2H3,(H2,11,12,13)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) Show SMILES Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12 Show InChI InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10907 (4-(3,5-Dimethylbenzyl)-5-ethyl-3-formamido-6-methy...) Show SMILES CCc1c(C)[nH]c(=O)c(NC=O)c1Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C18H22N2O2/c1-5-15-13(4)20-18(22)17(19-10-21)16(15)9-14-7-11(2)6-12(3)8-14/h6-8,10H,5,9H2,1-4H3,(H,19,21)(H,20,22)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540702 (CHEMBL4641618) Show SMILES OC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCCCCc2ccccc2)cc1 Show InChI InChI=1S/C31H28FN3O3/c32-25-13-9-23(10-14-25)19-35-20-27(28(21-35)29-18-30(31(36)37)34-33-29)24-11-15-26(16-12-24)38-17-5-4-8-22-6-2-1-3-7-22/h1-3,6-7,9-16,18,20-21H,4-5,8,17,19H2,(H,33,34)(H,36,37)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10904 (1-[(benzyloxy)methyl]-5-methyl-6-(phenylsulfanyl)-...) Show SMILES Cc1c(Sc2ccccc2)n(COCc2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C19H18N2O3S/c1-14-17(22)20-19(23)21(13-24-12-15-8-4-2-5-9-15)18(14)25-16-10-6-3-7-11-16/h2-11H,12-13H2,1H3,(H,20,22,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM10904 (1-[(benzyloxy)methyl]-5-methyl-6-(phenylsulfanyl)-...) Show SMILES Cc1c(Sc2ccccc2)n(COCc2ccccc2)c(=O)[nH]c1=O Show InChI InChI=1S/C19H18N2O3S/c1-14-17(22)20-19(23)21(13-24-12-15-8-4-2-5-9-15)18(14)25-16-10-6-3-7-11-16/h2-11H,12-13H2,1H3,(H,20,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029678 (4-(3,5-Dimethyl-phenylsulfanyl)-5-ethyl-6-methyl-1...) Show SMILES CCc1c(C)[nH]c(=O)cc1Sc1cc(C)cc(C)c1 Show InChI InChI=1S/C16H19NOS/c1-5-14-12(4)17-16(18)9-15(14)19-13-7-10(2)6-11(3)8-13/h6-9H,5H2,1-4H3,(H,17,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50587966 (CHEMBL5188823) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccccc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029663 (4-(3,5-Dimethyl-phenylsulfanyl)-5-ethyl-6-methyl-2...) Show SMILES CCOC(=O)c1c(Sc2cc(C)cc(C)c2)c(CC)c(C)[nH]c1=O Show InChI InChI=1S/C19H23NO3S/c1-6-15-13(5)20-18(21)16(19(22)23-7-2)17(15)24-14-9-11(3)8-12(4)10-14/h8-10H,6-7H2,1-5H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587988 (CHEMBL5172754) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3cccc4ccccc34)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587969 (CHEMBL5173288) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3cccc4ccccc34)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540705 (CHEMBL4641010) Show SMILES OC(=O)c1cc(n[nH]1)-c1cn(Cc2cccc3ccccc23)cc1-c1ccc(OCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C36H27N3O3/c40-36(41)35-19-34(37-38-35)33-22-39(20-27-11-5-9-24-7-1-3-13-30(24)27)21-32(33)26-15-17-29(18-16-26)42-23-28-12-6-10-25-8-2-4-14-31(25)28/h1-19,21-22H,20,23H2,(H,37,38)(H,40,41)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587990 (CHEMBL5182942) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3cccc(Cl)c3Cl)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587968 (CHEMBL5198940) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccc(Cl)c(Cl)c3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587974 (CHEMBL5185855) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccc(Oc4ccccc4)cc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540703 (CHEMBL4639414) Show SMILES OC(=O)c1cc(n[nH]1)-c1cn(Cc2cccc3ccccc23)cc1-c1ccc(OCCCCc2ccccc2)cc1 Show InChI InChI=1S/C35H31N3O3/c39-35(40)34-21-33(36-37-34)32-24-38(22-28-14-8-13-26-12-4-5-15-30(26)28)23-31(32)27-16-18-29(19-17-27)41-20-7-6-11-25-9-2-1-3-10-25/h1-5,8-10,12-19,21,23-24H,6-7,11,20,22H2,(H,36,37)(H,39,40)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540701 (CHEMBL4648383) Show SMILES OC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C28H22FN3O3/c29-22-10-6-19(7-11-22)15-32-16-24(25(17-32)26-14-27(28(33)34)31-30-26)21-8-12-23(13-9-21)35-18-20-4-2-1-3-5-20/h1-14,16-17H,15,18H2,(H,30,31)(H,33,34)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50587968 (CHEMBL5198940) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccc(Cl)c(Cl)c3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50587965 (CHEMBL5176128) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(\C=C\C(=O)c3ccccc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029679 (3-Amino-5-methyl-4-m-tolylsulfanyl-1H-pyridin-2-on...) Show SMILES Cc1cccc(Sc2c(C)c[nH]c(=O)c2N)c1 Show InChI InChI=1S/C13H14N2OS/c1-8-4-3-5-10(6-8)17-12-9(2)7-15-13(16)11(12)14/h3-7H,14H2,1-2H3,(H,15,16)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029671 (CHEMBL126931 | N-[4-(3,5-Dimethyl-phenylsulfanyl)-...) Show SMILES CCC(=O)Nc1c(Sc2cc(C)cc(C)c2)c(C)c[nH]c1=O Show InChI InChI=1S/C17H20N2O2S/c1-5-14(20)19-15-16(12(4)9-18-17(15)21)22-13-7-10(2)6-11(3)8-13/h6-9H,5H2,1-4H3,(H,18,21)(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50029672 (CHEMBL341880 | N-[4-(3,5-Dimethyl-phenylsulfanyl)-...) Show SMILES CC(=O)Nc1c(Sc2cc(C)cc(C)c2)c(C)c[nH]c1=O Show InChI InChI=1S/C16H18N2O2S/c1-9-5-10(2)7-13(6-9)21-15-11(3)8-17-16(20)14(15)18-12(4)19/h5-8H,1-4H3,(H,17,20)(H,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540696 (CHEMBL4643229) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1cn(Cc2cccc3ccccc23)cc1-c1ccc(OCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C38H31N3O3/c1-2-43-38(42)37-21-36(39-40-37)35-24-41(22-29-13-7-11-26-9-3-5-15-32(26)29)23-34(35)28-17-19-31(20-18-28)44-25-30-14-8-12-27-10-4-6-16-33(27)30/h3-21,23-24H,2,22,25H2,1H3,(H,39,40)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540704 (CHEMBL4634514) Show SMILES OC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C32H24FN3O3/c33-25-12-8-21(9-13-25)17-36-18-28(29(19-36)30-16-31(32(37)38)35-34-30)23-10-14-26(15-11-23)39-20-24-6-3-5-22-4-1-2-7-27(22)24/h1-16,18-19H,17,20H2,(H,34,35)(H,37,38)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587971 (CHEMBL5183730) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccc4OCOc4c3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540692 (CHEMBL4649730) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C30H26FN3O3/c1-2-36-30(35)29-16-28(32-33-29)27-19-34(17-21-8-12-24(31)13-9-21)18-26(27)23-10-14-25(15-11-23)37-20-22-6-4-3-5-7-22/h3-16,18-19H,2,17,20H2,1H3,(H,32,33)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540695 (CHEMBL4638007) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C34H28FN3O3/c1-2-40-34(39)33-18-32(36-37-33)31-21-38(19-23-10-14-27(35)15-11-23)20-30(31)25-12-16-28(17-13-25)41-22-26-8-5-7-24-6-3-4-9-29(24)26/h3-18,20-21H,2,19,22H2,1H3,(H,36,37)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587967 (CHEMBL5197780) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3cccc(Cl)c3Cl)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540708 (CHEMBL4640609) Show SMILES OC(=O)c1cc(n[nH]1)-c1cn(Cc2cccc3ccccc23)cc1-c1ccc(OCC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C33H26N4O4/c38-32(34-25-10-2-1-3-11-25)21-41-26-15-13-23(14-16-26)28-19-37(20-29(28)30-17-31(33(39)40)36-35-30)18-24-9-6-8-22-7-4-5-12-27(22)24/h1-17,19-20H,18,21H2,(H,34,38)(H,35,36)(H,39,40)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587965 (CHEMBL5176128) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(\C=C\C(=O)c3ccccc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50004152 ((HEPT) 1-(2-Hydroxy-ethoxymethyl)-5-methyl-6-pheny...) Show SMILES Cc1c(Sc2ccccc2)n(COCCO)c(=O)[nH]c1=O Show InChI InChI=1S/C14H16N2O4S/c1-10-12(18)15-14(19)16(9-20-8-7-17)13(10)21-11-5-3-2-4-6-11/h2-6,17H,7-9H2,1H3,(H,15,18,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	>6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
URA 1387 CNRS Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase(RT)				J Med Chem 38: 4679-86 (1995) BindingDB Entry DOI: 10.7270/Q2QF8RWD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540698 (CHEMBL4644576) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C31H27FN4O4/c1-2-39-31(38)29-16-28(34-35-29)27-19-36(17-21-8-12-23(32)13-9-21)18-26(27)22-10-14-25(15-11-22)40-20-30(37)33-24-6-4-3-5-7-24/h3-16,18-19H,2,17,20H2,1H3,(H,33,37)(H,34,35)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540710 (CHEMBL4643404) Show SMILES CCOC(=O)C(\O)=C\C(=O)\C=C\c1cccn1Cc1ccccc1Cl Show InChI InChI=1S/C19H18ClNO4/c1-2-25-19(24)18(23)12-16(22)10-9-15-7-5-11-21(15)13-14-6-3-4-8-17(14)20/h3-12,23H,2,13H2,1H3/b10-9+,18-12-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant HIV-1 reverse transcriptase p66/p51 expressed in Escherichia coli M15 using 5'-[gamma32P]ATP-labeled-tC...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587973 (CHEMBL5198310) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccc(cc3)-c3ccccc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587974 (CHEMBL5185855) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccc(Oc4ccccc4)cc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540699 (CHEMBL4648093) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1cn(Cc2cccc3ccccc23)cc1-c1ccc(OCC(=O)Nc2ccccc2)cc1 Show InChI InChI=1S/C35H30N4O4/c1-2-42-35(41)33-19-32(37-38-33)31-22-39(20-26-11-8-10-24-9-6-7-14-29(24)26)21-30(31)25-15-17-28(18-16-25)43-23-34(40)36-27-12-4-3-5-13-27/h3-19,21-22H,2,20,23H2,1H3,(H,36,40)(H,37,38)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587991 (CHEMBL5174596) Show SMILES CCOC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3ccccc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50540697 (CHEMBL4633074) Show SMILES CCOC(=O)c1cc(n[nH]1)-c1cn(Cc2ccc(F)cc2)cc1-c1ccc(OCC(=O)Nc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C32H27FN4O6/c1-2-42-32(41)29-15-28(35-36-29)27-18-37(16-20-3-9-23(33)10-4-20)17-26(27)21-7-13-25(14-8-21)43-19-30(38)34-24-11-5-22(6-12-24)31(39)40/h3-15,17-18H,2,16,19H2,1H3,(H,34,38)(H,35,36)(H,39,40)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
"Sapienza" Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...				ACS Med Chem Lett 11: 798-805 (2020) Article DOI: 10.1021/acsmedchemlett.9b00617 BindingDB Entry DOI: 10.7270/Q2T1576W
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587967 (CHEMBL5197780) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCc3cccc(Cl)c3Cl)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50587972 (CHEMBL5202973) Show SMILES OC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(OCCCCc3ccccc3)cc2c1=O Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00535 BindingDB Entry DOI: 10.7270/Q2V98D1X
					More data for this Ligand-Target Pair

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