Compile Data Set for Download or QSAR

Found 105 hits with Last Name = 'green' and Initial = 'dv'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3386 (7-[2-(1H-Imidazol-l-yl)-5-methylimidazo[1,5-b]pyri...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)-n1ccnc1 Show InChI InChI=1S/C23H25N5O/c1-18-20-13-14-23(27-16-15-24-17-27)26-28(20)22(25-18)12-8-3-2-7-11-21(29)19-9-5-4-6-10-19/h4-6,9-10,13-17H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470139 (CHEMBL46745) Show SMILES Fc1ccc(OCC(=O)Nc2ccccc2)c(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C21H16FNO3/c22-16-11-12-19(18(13-16)21(25)15-7-3-1-4-8-15)26-14-20(24)23-17-9-5-2-6-10-17/h1-13H,14H2,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.59	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470155 (CHEMBL288971) Show SMILES Clc1ccc(OCC(=O)N2CCc3ccccc3C2)c(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C24H20ClNO3/c25-20-10-11-22(21(14-20)24(28)18-7-2-1-3-8-18)29-16-23(27)26-13-12-17-6-4-5-9-19(17)15-26/h1-11,14H,12-13,15-16H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14.8	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470136 (CHEMBL296939 | GF-128590) Show SMILES Clc1ccc(OCC(=O)Nc2ccccc2)c(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C21H16ClNO3/c22-16-11-12-19(18(13-16)21(25)15-7-3-1-4-8-15)26-14-20(24)23-17-9-5-2-6-10-17/h1-13H,14H2,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	27.3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair				3D Structure (crystal)
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470145 (CHEMBL46925) Show SMILES Clc1cc(OCC(=O)Nc2ccccc2)c(cc1Cl)C(=O)c1ccccc1 Show InChI InChI=1S/C21H15Cl2NO3/c22-17-11-16(21(26)14-7-3-1-4-8-14)19(12-18(17)23)27-13-20(25)24-15-9-5-2-6-10-15/h1-12H,13H2,(H,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3383 (7-[5-Methyl-2-(1-pyrrolidinyl)imidazo[1,5-b]pyrida...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)N1CCCC1 Show InChI InChI=1S/C24H30N4O/c1-19-21-15-16-24(27-17-9-10-18-27)26-28(21)23(25-19)14-8-3-2-7-13-22(29)20-11-5-4-6-12-20/h4-6,11-12,15-16H,2-3,7-10,13-14,17-18H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3385 (7-[5-methyl-2-(1H-pyrrol-1-yl)imidazo[1,5-a]pyrida...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)-n1cccc1 Show InChI InChI=1S/C24H26N4O/c1-19-21-15-16-24(27-17-9-10-18-27)26-28(21)23(25-19)14-8-3-2-7-13-22(29)20-11-5-4-6-12-20/h4-6,9-12,15-18H,2-3,7-8,13-14H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3379 (7-[5-Methyl-2-(methylthio)imidazo[1,5-b]pyridazin-...) Show SMILES CSc1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C21H25N3OS/c1-16-18-14-15-21(26-2)23-24(18)20(22-16)13-9-4-3-8-12-19(25)17-10-6-5-7-11-17/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3392 (7-[5-methyl-2-(5-methyl-1H-imidazol-1-yl)imidazo[1...) Show SMILES Cc1cncn1-c1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C24H27N5O/c1-18-16-25-17-28(18)24-15-14-21-19(2)26-23(29(21)27-24)13-9-4-3-8-12-22(30)20-10-6-5-7-11-20/h5-7,10-11,14-17H,3-4,8-9,12-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3388 (7-[5-methyl-2-(1H-1,2,4-triazol-1-yl)imidazo[1,5-a...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)-n1cncn1 Show InChI InChI=1S/C22H24N6O/c1-17-19-13-14-22(27-16-23-15-24-27)26-28(19)21(25-17)12-8-3-2-7-11-20(29)18-9-5-4-6-10-18/h4-6,9-10,13-16H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470146 (CHEMBL417183) Show SMILES Clc1ccc(OCC(=O)c2cc3ccccc3[nH]2)c(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C23H16ClNO3/c24-17-10-11-22(18(13-17)23(27)15-6-2-1-3-7-15)28-14-21(26)20-12-16-8-4-5-9-19(16)25-20/h1-13,25H,14H2	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470138 (CHEMBL46650) Show SMILES CN(C)CCCOc1ccc(NC(=O)COc2ccc(Cl)cc2C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C26H27ClN2O4/c1-29(2)15-6-16-32-22-12-10-21(11-13-22)28-25(30)18-33-24-14-9-20(27)17-23(24)26(31)19-7-4-3-5-8-19/h3-5,7-14,17H,6,15-16,18H2,1-2H3,(H,28,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3395 (7-[2-(1H-imidazol-1-yl)-5-methylimidazo[1,5-a]pyri...) Show SMILES Cc1nc(CCCCCCC(O)c2ccccc2)n2nc(ccc12)-n1ccnc1 Show InChI InChI=1S/C23H27N5O/c1-18-20-13-14-23(27-16-15-24-17-27)26-28(20)22(25-18)12-8-3-2-7-11-21(29)19-9-5-4-6-10-19/h4-6,9-10,13-17,21,29H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3382 (7-[2-(Dimethylamino)-5-methylimidazo[1,5-b]pyridaz...) Show SMILES CN(C)c1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C22H28N4O/c1-17-19-15-16-22(25(2)3)24-26(19)21(23-17)14-10-5-4-9-13-20(27)18-11-7-6-8-12-18/h6-8,11-12,15-16H,4-5,9-10,13-14H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3374 (7-{2-chloroimidazo[1,5-a]pyridazin-7-yl}-1-phenylh...) Show SMILES Clc1ccc2cnc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C19H20ClN3O/c20-18-13-12-16-14-21-19(23(16)22-18)11-7-2-1-6-10-17(24)15-8-4-3-5-9-15/h3-5,8-9,12-14H,1-2,6-7,10-11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3373 (( 1RS)-2-Chloro-5-methyl-alpha-phenyl-7-imidazo[1,...) Show SMILES Cc1nc(CCCCCCC(O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C20H24ClN3O/c1-15-17-13-14-19(21)23-24(17)20(22-15)12-8-3-2-7-11-18(25)16-9-5-4-6-10-16/h4-6,9-10,13-14,18,25H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470151 (CHEMBL297010) Show SMILES Clc1ccc(OCC(=O)Nc2ccccc2)c(c1)C(=O)c1cccnc1 Show InChI InChI=1S/C20H15ClN2O3/c21-15-8-9-18(17(11-15)20(25)14-5-4-10-22-12-14)26-13-19(24)23-16-6-2-1-3-7-16/h1-12H,13H2,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	436	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470144 (CHEMBL43263) Show SMILES CN(C)CCCOc1ccc(NC(=O)Cc2ccc(Cl)cc2C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C26H27ClN2O3/c1-29(2)15-6-16-32-23-13-11-22(12-14-23)28-25(30)17-20-9-10-21(27)18-24(20)26(31)19-7-4-3-5-8-19/h3-5,7-14,18H,6,15-17H2,1-2H3,(H,28,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	443	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3393 (7-[5-methyl-2-(4-methyl-1H-imidazol-1-yl)imidazo[1...) Show SMILES Cc1cn(cn1)-c1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C24H27N5O/c1-18-16-28(17-25-18)24-15-14-21-19(2)26-23(29(21)27-24)13-9-4-3-8-12-22(30)20-10-6-5-7-11-20/h5-7,10-11,14-17H,3-4,8-9,12-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3377 (7-(5-Methylimidazo[1,5-b]pyridazin-7-yl)-l-phenyl-...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2ncccc12 Show InChI InChI=1S/C20H23N3O/c1-16-18-12-9-15-21-23(18)20(22-16)14-8-3-2-7-13-19(24)17-10-5-4-6-11-17/h4-6,9-12,15H,2-3,7-8,13-14H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3389 (7-[5-methyl-2-(1H-1,2,3-triazol-1-yl)imidazo[1,5-a...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)-n1ccnn1 Show InChI InChI=1S/C22H24N6O/c1-17-19-13-14-22(27-16-15-23-26-27)25-28(19)21(24-17)12-8-3-2-7-11-20(29)18-9-5-4-6-10-18/h4-6,9-10,13-16H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3378 (7-(2-Methoxy-5-methylimidazo[1,5-b]pyridazin-7-y1)...) Show SMILES COc1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C21H25N3O2/c1-16-18-14-15-21(26-2)23-24(18)20(22-16)13-9-4-3-8-12-19(25)17-10-6-5-7-11-17/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470148 (CHEMBL42078) Show SMILES CN(C)CCCOc1ccc(NC(=O)Cc2ccc(Cl)cc2C(=O)c2ccccc2)c(C)c1 Show InChI InChI=1S/C27H29ClN2O3/c1-19-16-23(33-15-7-14-30(2)3)12-13-25(19)29-26(31)17-21-10-11-22(28)18-24(21)27(32)20-8-5-4-6-9-20/h4-6,8-13,16,18H,7,14-15,17H2,1-3H3,(H,29,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	752	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3365 (7-(2-Chloro-5-methylimidazo[1,5-b]pyridazin-7-yl)-...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C20H22ClN3O/c1-15-17-13-14-19(21)23-24(17)20(22-15)12-8-3-2-7-11-18(25)16-9-5-4-6-10-16/h4-6,9-10,13-14H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470137 (CHEMBL45100) Show SMILES CCN(CC)CCOc1ccc(NC(=O)COc2ccc(Cl)cc2C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H29ClN2O4/c1-3-30(4-2)16-17-33-23-13-11-22(12-14-23)29-26(31)19-34-25-15-10-21(28)18-24(25)27(32)20-8-6-5-7-9-20/h5-15,18H,3-4,16-17,19H2,1-2H3,(H,29,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	935	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3391 (7-[5-methyl-2-(2H-1,2,3-triazol-2-yl)imidazo[1,5-a...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)-n1nccn1 Show InChI InChI=1S/C22H24N6O/c1-17-19-13-14-22(28-23-15-16-24-28)26-27(19)21(25-17)12-8-3-2-7-11-20(29)18-9-5-4-6-10-18/h4-6,9-10,13-16H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3363 (5-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}p...) Show SMILES Cc1nc(CCCCCOC(=O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C19H20ClN3O2/c1-14-16-11-12-17(20)22-23(16)18(21-14)10-6-3-7-13-25-19(24)15-8-4-2-5-9-15/h2,4-5,8-9,11-12H,3,6-7,10,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470166 (CHEMBL44002) Show SMILES Clc1ccc(OCc2nc3ccccc3[nH]2)c(c1)C(=O)c1ccccc1 Show InChI InChI=1S/C21H15ClN2O2/c22-15-10-11-19(16(12-15)21(25)14-6-2-1-3-7-14)26-13-20-23-17-8-4-5-9-18(17)24-20/h1-12H,13H2,(H,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071777 (5-bromo-2-({6-[(4-bromo-2-carboxyphenyl)amino]-6-o...) Show SMILES OC(=O)c1cc(Br)ccc1NC(=O)CCCCC(=O)Nc1ccc(Br)cc1C(O)=O Show InChI InChI=1S/C20H18Br2N2O6/c21-11-5-7-15(13(9-11)19(27)28)23-17(25)3-1-2-4-18(26)24-16-8-6-12(22)10-14(16)20(29)30/h5-10H,1-4H2,(H,23,25)(H,24,26)(H,27,28)(H,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071776 (2-({6-[(2-carboxy-4-chlorophenyl)amino]-6-oxohexan...) Show SMILES OC(=O)c1cc(Cl)ccc1NC(=O)CCCCC(=O)Nc1ccc(Cl)cc1C(O)=O Show InChI InChI=1S/C20H18Cl2N2O6/c21-11-5-7-15(13(9-11)19(27)28)23-17(25)3-1-2-4-18(26)24-16-8-6-12(22)10-14(16)20(29)30/h5-10H,1-4H2,(H,23,25)(H,24,26)(H,27,28)(H,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-2 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3375 (7-{2-chloro-5-ethylimidazo[1,5-a]pyridazin-7-yl}-1...) Show SMILES CCc1nc(CCCCCCC(=O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C21H24ClN3O/c1-2-17-18-14-15-20(22)24-25(18)21(23-17)13-9-4-3-8-12-19(26)16-10-6-5-7-11-16/h5-7,10-11,14-15H,2-4,8-9,12-13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3364 (7-[5-(benzyloxy)pentyl]-2-chloro-5-methylimidazo[1...) Show SMILES Cc1nc(CCCCCOCc2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C19H22ClN3O/c1-15-17-11-12-18(20)22-23(17)19(21-15)10-6-3-7-13-24-14-16-8-4-2-5-9-16/h2,4-5,8-9,11-12H,3,6-7,10,13-14H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3394 (7-[5-methyl-2-(2-methyl-1H-imidazol-1-yl)imidazo[1...) Show SMILES Cc1nccn1-c1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C24H27N5O/c1-18-21-14-15-24(28-17-16-25-19(28)2)27-29(21)23(26-18)13-9-4-3-8-12-22(30)20-10-6-5-7-11-20/h5-7,10-11,14-17H,3-4,8-9,12-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3390 (7-[5-methyl-2-(4H-1,2,4-triazol-4-yl)imidazo[1,5-a...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)-n1cnnc1 Show InChI InChI=1S/C22H24N6O/c1-17-19-13-14-22(27-15-23-24-16-27)26-28(19)21(25-17)12-8-3-2-7-11-20(29)18-9-5-4-6-10-18/h4-6,9-10,13-16H,2-3,7-8,11-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3380 (7-(2-Amino-5-methylimidazo[1,5-b]pyridazin-7-yl)-l...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(N)ccc12 Show InChI InChI=1S/C20H24N4O/c1-15-17-13-14-19(21)23-24(17)20(22-15)12-8-3-2-7-11-18(25)16-9-5-4-6-10-16/h4-6,9-10,13-14H,2-3,7-8,11-12H2,1H3,(H2,21,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3369 (8-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-...) Show SMILES Cc1nc(CCCCCCCC(=O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C21H24ClN3O/c1-16-18-14-15-20(22)24-25(18)21(23-16)13-9-4-2-3-8-12-19(26)17-10-6-5-7-11-17/h5-7,10-11,14-15H,2-4,8-9,12-13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071777 (5-bromo-2-({6-[(4-bromo-2-carboxyphenyl)amino]-6-o...) Show SMILES OC(=O)c1cc(Br)ccc1NC(=O)CCCCC(=O)Nc1ccc(Br)cc1C(O)=O Show InChI InChI=1S/C20H18Br2N2O6/c21-11-5-7-15(13(9-11)19(27)28)23-17(25)3-1-2-4-18(26)24-16-8-6-12(22)10-14(16)20(29)30/h5-10H,1-4H2,(H,23,25)(H,24,26)(H,27,28)(H,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3387 (7-[5-methyl-2-(1H-pyrazol-1-yl)imidazo[1,5-a]pyrid...) Show SMILES Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(ccc12)-n1cccn1 Show InChI InChI=1S/C23H25N5O/c1-18-20-14-15-23(27-17-9-16-24-27)26-28(20)22(25-18)13-8-3-2-7-12-21(29)19-10-5-4-6-11-19/h4-6,9-11,14-17H,2-3,7-8,12-13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3381 (7-[5-methyl-2-(methylamino)imidazo[1,5-a]pyridazin...) Show SMILES CNc1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 Show InChI InChI=1S/C21H26N4O/c1-16-18-14-15-20(22-2)24-25(18)21(23-16)13-9-4-3-8-12-19(26)17-10-6-5-7-11-17/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071766 (5-bromo-2-[5-(4-bromo-2-carboxyphenylcarbamoyl)pen...) Show SMILES OC(=O)c1cc(Br)ccc1NC(=O)CCCCCC(=O)Nc1ccc(Br)cc1C(O)=O Show InChI InChI=1S/C21H20Br2N2O6/c22-12-6-8-16(14(10-12)20(28)29)24-18(26)4-2-1-3-5-19(27)25-17-9-7-13(23)11-15(17)21(30)31/h6-11H,1-5H2,(H,24,26)(H,25,27)(H,28,29)(H,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-2 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3367 (7-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-...) Show SMILES Cc1nc(CCCCCC(=O)Cc2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C20H22ClN3O/c1-15-18-12-13-19(21)23-24(18)20(22-15)11-7-3-6-10-17(25)14-16-8-4-2-5-9-16/h2,4-5,8-9,12-13H,3,6-7,10-11,14H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071768 (2-({6-[(2-carboxy-4-iodophenyl)amino]-6-oxohexanoy...) Show SMILES OC(=O)c1cc(I)ccc1NC(=O)CCCCC(=O)Nc1ccc(I)cc1C(O)=O Show InChI InChI=1S/C20H18I2N2O6/c21-11-5-7-15(13(9-11)19(27)28)23-17(25)3-1-2-4-18(26)24-16-8-6-12(22)10-14(16)20(29)30/h5-10H,1-4H2,(H,23,25)(H,24,26)(H,27,28)(H,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071765 (2-[4-(2-carboxy-4-methoxyphenylcarbamoyl)butylcarb...) Show SMILES COc1ccc(NC(=O)CCCCC(=O)Nc2ccc(OC)cc2C(O)=O)c(c1)C(O)=O Show InChI InChI=1S/C22H24N2O8/c1-31-13-7-9-17(15(11-13)21(27)28)23-19(25)5-3-4-6-20(26)24-18-10-8-14(32-2)12-16(18)22(29)30/h7-12H,3-6H2,1-2H3,(H,23,25)(H,24,26)(H,27,28)(H,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-2 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071766 (5-bromo-2-[5-(4-bromo-2-carboxyphenylcarbamoyl)pen...) Show SMILES OC(=O)c1cc(Br)ccc1NC(=O)CCCCCC(=O)Nc1ccc(Br)cc1C(O)=O Show InChI InChI=1S/C21H20Br2N2O6/c22-12-6-8-16(14(10-12)20(28)29)24-18(26)4-2-1-3-5-19(27)25-17-9-7-13(23)11-15(17)21(30)31/h6-11H,1-5H2,(H,24,26)(H,25,27)(H,28,29)(H,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-1 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3368 (6-{2-chloro-5-methylimidazo[1,5-a]pyridazin-7-yl}-...) Show SMILES Cc1nc(CCCCCC(=O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C19H20ClN3O/c1-14-16-12-13-18(20)22-23(16)19(21-14)11-7-3-6-10-17(24)15-8-4-2-5-9-15/h2,4-5,8-9,12-13H,3,6-7,10-11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470140 (CHEMBL42066) Show SMILES Clc1ccc(OCC(=O)Nc2ccccc2)c(c1)C(=O)C1CCCC1 Show InChI InChI=1S/C20H20ClNO3/c21-15-10-11-18(17(12-15)20(24)14-6-4-5-7-14)25-13-19(23)22-16-8-2-1-3-9-16/h1-3,8-12,14H,4-7,13H2,(H,22,23)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470152 (CHEMBL42823) Show SMILES CCN(CC)CCOc1ccc(NC(=O)COc2ccccc2C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C27H30N2O4/c1-3-29(4-2)18-19-32-23-16-14-22(15-17-23)28-26(30)20-33-25-13-9-8-12-24(25)27(31)21-10-6-5-7-11-21/h5-17H,3-4,18-20H2,1-2H3,(H,28,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470168 (CHEMBL46977) Show SMILES CCc1cc(OCCCN(C)C)ccc1NC(=O)Cc1ccc(Cl)cc1C(=O)c1ccccc1 Show InChI InChI=1S/C28H31ClN2O3/c1-4-20-17-24(34-16-8-15-31(2)3)13-14-26(20)30-27(32)18-22-11-12-23(29)19-25(22)28(33)21-9-6-5-7-10-21/h5-7,9-14,17,19H,4,8,15-16,18H2,1-3H3,(H,30,32)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50071771 (5-bromo-2-{[(5-{[(4-bromo-2-carboxyphenyl)amino]ca...) Show SMILES OC(=O)c1cc(Br)ccc1NC(=O)c1ccc(nc1)C(=O)Nc1ccc(Br)cc1C(O)=O Show InChI InChI=1S/C21H13Br2N3O6/c22-11-2-5-15(13(7-11)20(29)30)25-18(27)10-1-4-17(24-9-10)19(28)26-16-6-3-12(23)8-14(16)21(31)32/h1-9H,(H,25,27)(H,26,28)(H,29,30)(H,31,32)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoWellcome Medicines Research Center Curated by ChEMBL					Assay Description Evaluated for inhibition of HIV-2 reverse transcriptase				Bioorg Med Chem Lett 8: 2623-8 (1999) BindingDB Entry DOI: 10.7270/Q2RF5T6F
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50470142 (CHEMBL46675) Show SMILES Cc1ccccc1CNC(=O)COc1ccc(Cl)cc1C(=O)c1ccccc1 Show InChI InChI=1S/C23H20ClNO3/c1-16-7-5-6-10-18(16)14-25-22(26)15-28-21-12-11-19(24)13-20(21)23(27)17-8-3-2-4-9-17/h2-13H,14-15H2,1H3,(H,25,26)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research and Development Limited Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 reverse transcriptase				J Med Chem 38: 1657-65 (1995) Article DOI: 10.1021/jm00010a010 BindingDB Entry DOI: 10.7270/Q27947DP
					More data for this Ligand-Target Pair

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