Compile Data Set for Download or QSAR

Found 130 hits with Last Name = 'hardy' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092485 (4-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]...) Show SMILES CC1=C2CCc3cc(Cl)ccc3N2CCC1=O |c:1| Show InChI InChI=1S/C14H14ClNO/c1-9-12-4-2-10-8-11(15)3-5-13(10)16(12)7-6-14(9)17/h3,5,8H,2,4,6-7H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition constant against recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092492 (4,8-Dimethyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quino...) Show SMILES CC1=C2CCc3cc(C)ccc3N2CCC1=O |c:1| Show InChI InChI=1S/C15H17NO/c1-10-3-5-14-12(9-10)4-6-13-11(2)15(17)7-8-16(13)14/h3,5,9H,4,6-8H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition constant against recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50334788 ((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...) Show SMILES CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C |r,c:18| Show InChI InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	366	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human))	BDBM50334788 ((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...) Show SMILES CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C |r,c:18| Show InChI InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against steroid 5-alpha-reductase type 2 in human prostate homogenates				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50368782 (Bexlosteride | CHEMBL24955 | LY-191704) Show SMILES CN1[C@@H]2CCc3cc(Cl)ccc3[C@H]2CCC1=O Show InChI InChI=1S/C14H16ClNO/c1-16-13-6-2-9-8-10(15)3-4-11(9)12(13)5-7-14(16)17/h3-4,8,12-13H,2,5-7H2,1H3/t12-,13-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase type I in human scalp homogenates				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110881 (4-(2-oxo-3-(4-(5-phenylpentylthio)phenoxy)propoxy)...) Show SMILES OC(=O)c1ccc(OCC(=O)COc2ccc(SCCCCCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H28O5S/c28-23(19-31-24-12-10-22(11-13-24)27(29)30)20-32-25-14-16-26(17-15-25)33-18-6-2-5-9-21-7-3-1-4-8-21/h1,3-4,7-8,10-17H,2,5-6,9,18-20H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092485 (4-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]...) Show SMILES CC1=C2CCc3cc(Cl)ccc3N2CCC1=O |c:1| Show InChI InChI=1S/C14H14ClNO/c1-9-12-4-2-10-8-11(15)3-5-13(10)16(12)7-6-14(9)17/h3,5,8H,2,4,6-7H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110846 (4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic ac...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-18-30-23-14-16-25(17-15-23)32-20-22(27)19-31-24-12-10-21(11-13-24)26(28)29/h10-17H,2-9,18-20H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092506 (4,6-dimethyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,...) Show SMILES CC1CC2=C(C)C(=O)CCN2c2ccc(Cl)cc12 |c:3| Show InChI InChI=1S/C15H16ClNO/c1-9-7-14-10(2)15(18)5-6-17(14)13-4-3-11(16)8-12(9)13/h3-4,8-9H,5-7H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092489 (6-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]...) Show SMILES CC1CC2=CC(=O)CCN2c2ccc(Cl)cc12 |t:3| Show InChI InChI=1S/C14H14ClNO/c1-9-6-11-8-12(17)4-5-16(11)14-3-2-10(15)7-13(9)14/h2-3,7-9H,4-6H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14.4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase [136-227] (Sus scrofa)	BDBM50040461 ((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...) Show SMILES OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C31H37NO3S/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)24-36-29-20-17-27(18-21-29)23-26-14-8-4-9-15-26/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092500 (4,5-dimethyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,...) Show SMILES CC1Cc2cc(Cl)ccc2N2CCC(=O)C(C)=C12 |t:17| Show InChI InChI=1S/C15H16ClNO/c1-9-7-11-8-12(16)3-4-13(11)17-6-5-14(18)10(2)15(9)17/h3-4,8-9H,5-7H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15.6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092503 (4,6-dimethyl-8-methyl-1,2,5,6-tetrahydro pyrido[1,...) Show SMILES CC1CC2=C(C)C(=O)CCN2c2ccc(C)cc12 |c:3| Show InChI InChI=1S/C16H19NO/c1-10-4-5-14-13(8-10)11(2)9-15-12(3)16(18)6-7-17(14)15/h4-5,8,11H,6-7,9H2,1-3H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant Steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase [136-227] (Sus scrofa)	BDBM50040458 ((S)-4-((S)-(E)-Dec-3-enoylamino)-5-(naphthalen-2-y...) Show SMILES CCCCCC\C=C\CC(=O)N[C@@H](CCC(O)=O)CSc1ccc2ccccc2c1 Show InChI InChI=1S/C25H33NO3S/c1-2-3-4-5-6-7-8-13-24(27)26-22(15-17-25(28)29)19-30-23-16-14-20-11-9-10-12-21(20)18-23/h7-12,14,16,18,22H,2-6,13,15,17,19H2,1H3,(H,26,27)(H,28,29)/b8-7+/t22-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110859 (CHEMBL26200 | {4-[3-(4-Decyloxy-phenoxy)-2-oxo-pro...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(CC(O)=O)cc2)cc1 Show InChI InChI=1S/C27H36O6/c1-2-3-4-5-6-7-8-9-18-31-24-14-16-26(17-15-24)33-21-23(28)20-32-25-12-10-22(11-13-25)19-27(29)30/h10-17H,2-9,18-21H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092492 (4,8-Dimethyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quino...) Show SMILES CC1=C2CCc3cc(C)ccc3N2CCC1=O |c:1| Show InChI InChI=1S/C15H17NO/c1-10-3-5-14-12(9-10)4-6-13-11(2)15(17)7-8-16(13)14/h3,5,9H,4,6-8H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110854 (4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-3-nitro-b...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2[N+]([O-])=O)C(O)=O)cc1 Show InChI InChI=1S/C26H33NO8/c1-2-3-4-5-6-7-8-9-16-33-22-11-13-23(14-12-22)34-18-21(28)19-35-25-15-10-20(26(29)30)17-24(25)27(31)32/h10-15,17H,2-9,16,18-19H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50040461 ((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...) Show SMILES OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C31H37NO3S/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)24-36-29-20-17-27(18-21-29)23-26-14-8-4-9-15-26/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description Compound was tested for in vitro activity against s-phospholipase A2 (s-PLA2) isolated from human platelets				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-activating factor acetylhydrolase [136-227] (Sus scrofa)	BDBM50040464 ((S)-3-((S)-(E)-Dec-3-enoylamino)-4-(naphthalen-2-y...) Show SMILES CCCCCC\C=C\CC(=O)N[C@H](CSc1ccc2ccccc2c1)CC(O)=O Show InChI InChI=1S/C24H31NO3S/c1-2-3-4-5-6-7-8-13-23(26)25-21(17-24(27)28)18-29-22-15-14-19-11-9-10-12-20(19)16-22/h7-12,14-16,21H,2-6,13,17-18H2,1H3,(H,25,26)(H,27,28)/b8-7+/t21-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110873 (4-[3-(4-Dodecyloxy-phenoxy)-2-oxo-propoxy]-benzoic...) Show SMILES CCCCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C28H38O6/c1-2-3-4-5-6-7-8-9-10-11-20-32-25-16-18-27(19-17-25)34-22-24(29)21-33-26-14-12-23(13-15-26)28(30)31/h12-19H,2-11,20-22H2,1H3,(H,30,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase [136-227] (Sus scrofa)	BDBM50040461 ((S)-5-(4-Benzyl-phenylsulfanyl)-4-((S)-7-phenyl-he...) Show SMILES OC(=O)CC[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C31H37NO3S/c33-30(16-10-2-1-5-11-25-12-6-3-7-13-25)32-28(19-22-31(34)35)24-36-29-20-17-27(18-21-29)23-26-14-8-4-9-15-26/h3-4,6-9,12-15,17-18,20-21,28H,1-2,5,10-11,16,19,22-24H2,(H,32,33)(H,34,35)/t28-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description Compound was tested for in vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and micellar substrate with deoxycholate (DOC)				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110846 (4-(3-(4-(decyloxy)phenoxy)-2-oxopropoxy)benzoic ac...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-18-30-23-14-16-25(17-15-23)32-20-22(27)19-31-24-12-10-21(11-13-24)26(28)29/h10-17H,2-9,18-20H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110875 (5-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-pentanoic...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COCCCCC(O)=O)cc1 Show InChI InChI=1S/C24H38O6/c1-2-3-4-5-6-7-8-10-18-29-22-13-15-23(16-14-22)30-20-21(25)19-28-17-11-9-12-24(26)27/h13-16H,2-12,17-20H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase [136-227] (Sus scrofa)	BDBM50040455 ((S)-4-(4-Benzyl-phenylsulfanyl)-3-((S)-(E)-dec-3-e...) Show SMILES CCCCCC\C=C\CC(=O)N[C@H](CSc1ccc(Cc2ccccc2)cc1)CC(O)=O Show InChI InChI=1S/C27H35NO3S/c1-2-3-4-5-6-7-11-14-26(29)28-24(20-27(30)31)21-32-25-17-15-23(16-18-25)19-22-12-9-8-10-13-22/h7-13,15-18,24H,2-6,14,19-21H2,1H3,(H,28,29)(H,30,31)/b11-7+/t24-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110865 (3-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxymethyl]-ben...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COCc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C27H36O6/c1-2-3-4-5-6-7-8-9-17-32-25-13-15-26(16-14-25)33-21-24(28)20-31-19-22-11-10-12-23(18-22)27(29)30/h10-16,18H,2-9,17,19-21H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110872 (4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxymethyl]-ben...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COCc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C27H36O6/c1-2-3-4-5-6-7-8-9-18-32-25-14-16-26(17-15-25)33-21-24(28)20-31-19-22-10-12-23(13-11-22)27(29)30/h10-17H,2-9,18-21H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092492 (4,8-Dimethyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quino...) Show SMILES CC1=C2CCc3cc(C)ccc3N2CCC1=O |c:1| Show InChI InChI=1S/C15H17NO/c1-10-3-5-14-12(9-10)4-6-13-11(2)15(17)7-8-16(13)14/h3,5,9H,4,6-8H2,1-2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase type I in human scalp homogenates				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092485 (4-methyl-8-chloro-1,2,5,6-tetrahydro pyrido[1,2-a]...) Show SMILES CC1=C2CCc3cc(Cl)ccc3N2CCC1=O |c:1| Show InChI InChI=1S/C14H14ClNO/c1-9-12-4-2-10-8-11(15)3-5-13(10)16(12)7-6-14(9)17/h3,5,8H,2,4,6-7H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against Steroid 5-alpha-reductase type I in human scalp homogenates				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110884 (4-[3-(4-Octyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...) Show SMILES CCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2)C(O)=O)cc1 Show InChI InChI=1S/C24H30O6/c1-2-3-4-5-6-7-16-28-21-12-14-23(15-13-21)30-18-20(25)17-29-22-10-8-19(9-11-22)24(26)27/h8-15H,2-7,16-18H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110879 (4-{2-Oxo-3-[4-(5-phenyl-pentyloxy)-phenoxy]-propox...) Show SMILES OC(=O)c1ccc(OCC(=O)COc2ccc(OCCCCCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H28O6/c28-23(19-32-25-12-10-22(11-13-25)27(29)30)20-33-26-16-14-24(15-17-26)31-18-6-2-5-9-21-7-3-1-4-8-21/h1,3-4,7-8,10-17H,2,5-6,9,18-20H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50085564 (8-Chloro-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-...) Show SMILES Clc1ccc2N3CCC(=O)C=C3CCc2c1 |c:10| Show InChI InChI=1S/C13H12ClNO/c14-10-2-4-13-9(7-10)1-3-11-8-12(16)5-6-15(11)13/h2,4,7-8H,1,3,5-6H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110888 (3-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-benzoic a...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C26H34O6/c1-2-3-4-5-6-7-8-9-17-30-23-13-15-24(16-14-23)31-19-22(27)20-32-25-12-10-11-21(18-25)26(28)29/h10-16,18H,2-9,17,19-20H2,1H3,(H,28,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110860 (CHEMBL29247 | {3-[3-(4-Decyloxy-phenoxy)-2-oxo-pro...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(CC(O)=O)c2)cc1 Show InChI InChI=1S/C27H36O6/c1-2-3-4-5-6-7-8-9-17-31-24-13-15-25(16-14-24)32-20-23(28)21-33-26-12-10-11-22(18-26)19-27(29)30/h10-16,18H,2-9,17,19-21H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110853 (CHEMBL29246 | {3-[3-(4-Decyloxy-phenoxy)-2-oxo-pro...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(OCC(O)=O)c2)cc1 Show InChI InChI=1S/C27H36O7/c1-2-3-4-5-6-7-8-9-17-31-23-13-15-24(16-14-23)32-19-22(28)20-33-25-11-10-12-26(18-25)34-21-27(29)30/h10-16,18H,2-9,17,19-21H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50040466 ((S)-4-(4-Benzyl-phenylsulfanyl)-3-((S)-7-phenyl-he...) Show SMILES OC(=O)C[C@@H](CSc1ccc(Cc2ccccc2)cc1)NC(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C30H35NO3S/c32-29(16-10-2-1-5-11-24-12-6-3-7-13-24)31-27(22-30(33)34)23-35-28-19-17-26(18-20-28)21-25-14-8-4-9-15-25/h3-4,6-9,12-15,17-20,27H,1-2,5,10-11,16,21-23H2,(H,31,32)(H,33,34)/t27-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description Compound was tested for in vitro activity against s-phospholipase A2 (s-PLA2) isolated from human platelets				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110863 (5-[3-(4-Decyloxy-phenoxy)-2-oxo-propylsulfanyl]-pe...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)CSCCCCC(O)=O)cc1 Show InChI InChI=1S/C24H38O5S/c1-2-3-4-5-6-7-8-10-17-28-22-13-15-23(16-14-22)29-19-21(25)20-30-18-11-9-12-24(26)27/h13-16H,2-12,17-20H2,1H3,(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110871 (4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-3-methoxy...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2OC)C(O)=O)cc1 Show InChI InChI=1S/C27H36O7/c1-3-4-5-6-7-8-9-10-17-32-23-12-14-24(15-13-23)33-19-22(28)20-34-25-16-11-21(27(29)30)18-26(25)31-2/h11-16,18H,3-10,17,19-20H2,1-2H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by bilayer assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110881 (4-(2-oxo-3-(4-(5-phenylpentylthio)phenoxy)propoxy)...) Show SMILES OC(=O)c1ccc(OCC(=O)COc2ccc(SCCCCCc3ccccc3)cc2)cc1 Show InChI InChI=1S/C27H28O5S/c28-23(19-31-24-12-10-22(11-13-24)27(29)30)20-32-25-14-16-26(17-15-25)33-18-6-2-5-9-21-7-3-1-4-8-21/h1,3-4,7-8,10-17H,2,5-6,9,18-20H2,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase [136-227] (Sus scrofa)	BDBM50040465 ((S)-3-((S)-(E)-Dec-3-enoylamino)-4-phenylsulfanyl-...) Show SMILES CCCCCC\C=C\CC(=O)N[C@H](CSc1ccccc1)CC(O)=O Show InChI InChI=1S/C20H29NO3S/c1-2-3-4-5-6-7-11-14-19(22)21-17(15-20(23)24)16-25-18-12-9-8-10-13-18/h7-13,17H,2-6,14-16H2,1H3,(H,21,22)(H,23,24)/b11-7+/t17-/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110854 (4-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxy]-3-nitro-b...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(cc2[N+]([O-])=O)C(O)=O)cc1 Show InChI InChI=1S/C26H33NO8/c1-2-3-4-5-6-7-8-9-16-33-22-11-13-23(14-12-22)34-18-21(28)19-35-25-15-10-20(26(29)30)17-24(25)27(31)32/h10-15,17H,2-9,16,18-19H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Group 10 secretory phospholipase A2 (Homo sapiens (Human))	BDBM50040455 ((S)-4-(4-Benzyl-phenylsulfanyl)-3-((S)-(E)-dec-3-e...) Show SMILES CCCCCC\C=C\CC(=O)N[C@H](CSc1ccc(Cc2ccccc2)cc1)CC(O)=O Show InChI InChI=1S/C27H35NO3S/c1-2-3-4-5-6-7-11-14-26(29)28-24(20-27(30)31)21-32-25-17-15-23(16-18-25)19-22-12-9-8-10-13-22/h7-13,15-18,24H,2-6,14,19-21H2,1H3,(H,28,29)(H,30,31)/b11-7+/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and micellar substrate with deoxycholate (DOC)				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092494 (4-(alpha)methyl-8-methyl-3,4,5,6-Tetrahydrobenzo[c...) Show SMILES C[C@H]1C2CCc3cc(C)ccc3N2C=CC1=O |c:15| Show InChI InChI=1S/C15H17NO/c1-10-3-5-14-12(9-10)4-6-13-11(2)15(17)7-8-16(13)14/h3,5,7-9,11,13H,4,6H2,1-2H3/t11-,13?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092487 (4-(alpha)methyl-8-chloro-3,4,5,6-Tetrahydrobenzo[c...) Show SMILES CC1C2CCc3cc(Cl)ccc3N2C=CC1=O |c:15| Show InChI InChI=1S/C14H14ClNO/c1-9-12-4-2-10-8-11(15)3-5-13(10)16(12)7-6-14(9)17/h3,5-9,12H,2,4H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110878 (4-[3-(4-Decyloxy-phenoxy)-2-oxo-propylsulfanyl]-bu...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)CSCCCC(O)=O)cc1 Show InChI InChI=1S/C23H36O5S/c1-2-3-4-5-6-7-8-9-16-27-21-12-14-22(15-13-21)28-18-20(24)19-29-17-10-11-23(25)26/h12-15H,2-11,16-19H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110859 (CHEMBL26200 | {4-[3-(4-Decyloxy-phenoxy)-2-oxo-pro...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COc2ccc(CC(O)=O)cc2)cc1 Show InChI InChI=1S/C27H36O6/c1-2-3-4-5-6-7-8-9-18-31-24-14-16-26(17-15-24)33-21-23(28)20-32-25-12-10-22(11-13-25)19-27(29)30/h10-17H,2-9,18-21H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
Cytosolic phospholipase A2 beta (Homo sapiens (Human))	BDBM50110865 (3-[3-(4-Decyloxy-phenoxy)-2-oxo-propoxymethyl]-ben...) Show SMILES CCCCCCCCCCOc1ccc(OCC(=O)COCc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C27H36O6/c1-2-3-4-5-6-7-8-9-17-32-25-13-15-26(16-14-25)33-21-24(28)20-31-19-22-11-10-12-23(18-22)27(29)30/h10-16,18H,2-9,17,19-21H2,1H3,(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity against cytosolic Phospholipase A2 (PLA2) by soluble assay				J Med Chem 45: 1348-62 (2002) BindingDB Entry DOI: 10.7270/Q2F76BVP
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092504 (8-methyl-3,4,5,6-Tetrahydrobenzo[c]quinolizin-3-(4...) Show SMILES Cc1ccc2N3C=CC(=O)CC3CCc2c1 |c:6| Show InChI InChI=1S/C14H15NO/c1-10-2-5-14-11(8-10)3-4-12-9-13(16)6-7-15(12)14/h2,5-8,12H,3-4,9H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092502 (4-Methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quinolin-...) Show SMILES CC1=C2CCc3ccccc3N2CCC1=O |c:1| Show InChI InChI=1S/C14H15NO/c1-10-12-7-6-11-4-2-3-5-13(11)15(12)9-8-14(10)16/h2-5H,6-9H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human))	BDBM50092491 (6-(alpha)methyl-8-chloro-3,4,5,6-Tetrahydrobenzo[c...) Show SMILES C[C@@H]1CC2CC(=O)C=CN2c2ccc(Cl)cc12 |c:7| Show InChI InChI=1S/C14H14ClNO/c1-9-6-11-8-12(17)4-5-16(11)14-3-2-10(15)7-13(9)14/h2-5,7,9,11H,6,8H2,1H3/t9-,11?/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	188	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Inhibition of recombinant steroid 5-alpha-reductase type I expressed in CHO cells				J Med Chem 43: 3718-35 (2000) BindingDB Entry DOI: 10.7270/Q25B036J
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase [136-227] (Sus scrofa)	BDBM50040456 ((R)-3-((S)-Hexadecanoylamino)-5-methyl-hexanoic ac...) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@H](CC(C)C)CC(O)=O Show InChI InChI=1S/C23H45NO3/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(25)24-21(18-20(2)3)19-23(26)27/h20-21H,4-19H2,1-3H3,(H,24,25)(H,26,27)/t21-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Fisons plc Curated by ChEMBL					Assay Description In vitro activity against porcine pancreatic phospholipase-A2 (PLA2) and monomerically dispersed substrate				J Med Chem 37: 557-9 (1994) BindingDB Entry DOI: 10.7270/Q28W3CB7
					More data for this Ligand-Target Pair

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