Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139736 (US8895549, 11) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139746 (US8895549, 24) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.99 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139750 (US8895549, 9) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.02 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139741 (US8895549, 7) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.22 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139743 (US8895549, 8) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.62 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139754 (US8895549, 19) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.78 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139717 (US8895549, 2 | US9675616, 2 N-(8-{[(2R)-2-hydroxy-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.98 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139763 (US8895549, 37) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.98 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139752 (US8895549, 14) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.09 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139749 (US8895549, 40) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.09 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139747 (US8895549, 36) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.41 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139727 (US8895549, 5) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.68 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139745 (US8895549, 18) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139729 (US8895549, 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.94 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139738 (US8895549, 20) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139731 (US8895549, 28) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.71 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139737 (US8895549, 12) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.74 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139724 (US8895549, 4 | US9675616, 4 N-[8-({(2R)-3-[(2R,6S)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.85 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300498 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.17 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300495 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139764 (US8895549, 39) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.32 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139730 (US8895549, 17) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.36 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139735 (US8895549, 10) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.47 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139720 (US8895549, 27) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.52 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139748 (US8895549, 38) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.64 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139740 (US8895549, 41) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139761 (US8895549, 32) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.91 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139721 (US8895549, 3 | US9675616, 3 N-(8-{[(2S)-2-hydroxy-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139733 (US8895549, 35) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139739 (US8895549, 29) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.75 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139732 (US8895549, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.21 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139756 (US8895549, 23) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300498 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.72 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300675 (N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- {[2-(mo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.85 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139757 (US8895549, 25) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300545 (N-{6-[4-(dimethylamino)phenyl]pyridin-3-yl}-3-{[(2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139759 (US8895549, 30) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300439 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(mor...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139716 (US8895549, 21) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.37 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139715 (US8895549, Comparative Example 1 | US9675616, 1 N-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM139734 (US8895549, 6) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.96 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Intellectual Property GmbH US Patent | Assay Description As reagents for the kinase reaction itself and the quantification of the reaction product, the PI3-Kinase HTRF Assay kit from Millipore (#33-017) was... | US Patent US8895549 (2014) BindingDB Entry DOI: 10.7270/Q2NC5ZWF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM139715 (US8895549, Comparative Example 1 | US9675616, 1 N-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 mL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G... | US Patent US9675616 (2017) BindingDB Entry DOI: 10.7270/Q2H41PKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM179449 (US9675616, 6 2-Amino-N-(8-{[(2S)-2-hydroxy-3-{[(1S...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 nL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G... | US Patent US9675616 (2017) BindingDB Entry DOI: 10.7270/Q2H41PKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM179450 (US9675616, 7 2-Amino-N-(8-{[(2R)-2-hydroxy-3-{[(1S...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 nL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G... | US Patent US9675616 (2017) BindingDB Entry DOI: 10.7270/Q2H41PKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human)) | BDBM179448 (US9675616, 5 rel-2-Amino-N-(8-{[(2R)-2-hydroxy-3-{...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 nL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G... | US Patent US9675616 (2017) BindingDB Entry DOI: 10.7270/Q2H41PKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM179448 (US9675616, 5 rel-2-Amino-N-(8-{[(2R)-2-hydroxy-3-{...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 mL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G... | US Patent US9675616 (2017) BindingDB Entry DOI: 10.7270/Q2H41PKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM179449 (US9675616, 6 2-Amino-N-(8-{[(2S)-2-hydroxy-3-{[(1S...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 mL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G... | US Patent US9675616 (2017) BindingDB Entry DOI: 10.7270/Q2H41PKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human)) | BDBM179450 (US9675616, 7 2-Amino-N-(8-{[(2R)-2-hydroxy-3-{[(1S...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER INTELLECTUAL PROPERTY GMBH US Patent | Assay Description For the assay 50 mL of a 80-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384-well microtiter plate (G... | US Patent US9675616 (2017) BindingDB Entry DOI: 10.7270/Q2H41PKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300440 (3-{[2-(morpholin-4-yl)propanoyl]amino}-N-(6-phenyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10.4 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Wnt-3a (Homo sapiens (Human)) | BDBM300496 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(4-m...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr... | US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G | |||||||||||
More data for this Ligand-Target Pair |
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