Compile Data Set for Download or QSAR

Found 69 hits with Last Name = 'richards' and Initial = 'wg'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367445 (CHEMBL49597) Show SMILES CCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301365 (CHEMBL570365 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccnc4)nc3)c2cc1OC Show InChI InChI=1S/C33H25N5O5/c1-41-29-16-25-27(17-30(29)42-2)35-14-12-28(25)43-24-10-11-31(36-19-24)37-32(39)26-15-22(21-7-6-13-34-18-21)20-38(33(26)40)23-8-4-3-5-9-23/h3-20H,1-2H3,(H,36,37,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301359 (CHEMBL570846 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4c(NC5CCOCC5)ccn(-c5ccccc5)c4=O)nc3)c2cc1OC Show InChI InChI=1S/C33H31N5O6/c1-41-28-18-24-26(19-29(28)42-2)34-14-10-27(24)44-23-8-9-30(35-20-23)37-32(39)31-25(36-21-12-16-43-17-13-21)11-15-38(33(31)40)22-6-4-3-5-7-22/h3-11,14-15,18-21,36H,12-13,16-17H2,1-2H3,(H,35,37,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301358 (CHEMBL568729 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COCCNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C31H29N5O6/c1-39-16-14-33-23-12-15-36(20-7-5-4-6-8-20)31(38)29(23)30(37)35-28-10-9-21(19-34-28)42-25-11-13-32-24-18-27(41-3)26(40-2)17-22(24)25/h4-13,15,17-19,33H,14,16H2,1-3H3,(H,34,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301364 (CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccs4)nc3)c2cc1OC Show InChI InChI=1S/C32H24N4O5S/c1-39-27-16-23-25(17-28(27)40-2)33-13-12-26(23)41-22-10-11-30(34-18-22)35-31(37)24-15-20(29-9-6-14-42-29)19-36(32(24)38)21-7-4-3-5-8-21/h3-19H,1-2H3,(H,34,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50453369 (CHEMBL48218) Show SMILES CCc1ccc(cc1)N1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C19H23NO/c1-2-15-8-10-18(11-9-15)20-12-4-6-17(14-20)16-5-3-7-19(21)13-16/h3,5,7-11,13,17,21H,2,4,6,12,14H2,1H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367445 (CHEMBL49597) Show SMILES CCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301362 (4-(2-methoxyethylamino)-N-(5-(7-methoxyquinolin-4-...) Show SMILES COCCNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)ccc23)cn1 Show InChI InChI=1S/C30H27N5O5/c1-38-17-15-32-24-13-16-35(20-6-4-3-5-7-20)30(37)28(24)29(36)34-27-11-9-22(19-33-27)40-26-12-14-31-25-18-21(39-2)8-10-23(25)26/h3-14,16,18-19,32H,15,17H2,1-2H3,(H,33,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301363 (1-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...) Show SMILES CNc1ccn(Cc2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C30H27N5O5/c1-31-22-12-14-35(18-19-7-5-4-6-8-19)30(37)28(22)29(36)34-27-10-9-20(17-33-27)40-24-11-13-32-23-16-26(39-3)25(38-2)15-21(23)24/h4-17,31H,18H2,1-3H3,(H,33,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301357 (CHEMBL572237 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4c(ccn(-c5ccccc5)c4=O)N(C)C)nc3)c2cc1OC Show InChI InChI=1S/C30H27N5O5/c1-34(2)23-13-15-35(19-8-6-5-7-9-19)30(37)28(23)29(36)33-27-11-10-20(18-32-27)40-24-12-14-31-22-17-26(39-4)25(38-3)16-21(22)24/h5-18H,1-4H3,(H,32,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol | 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50452348 (CHEMBL8033) Show SMILES Oc1cccc(c1)[C@@H]1CCCNC1 Show InChI InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50452349 (CHEMBL46256) Show SMILES CN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3/t11-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50452349 (CHEMBL46256) Show SMILES CN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3/t11-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301366 (5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(Cc5ccccc5)cn(-c5ccccc5)c4=O)nc3)c2cc1OC Show InChI InChI=1S/C35H28N4O5/c1-42-31-19-27-29(20-32(31)43-2)36-16-15-30(27)44-26-13-14-33(37-21-26)38-34(40)28-18-24(17-23-9-5-3-6-10-23)22-39(35(28)41)25-11-7-4-8-12-25/h3-16,18-22H,17H2,1-2H3,(H,37,38,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301366 (5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(Cc5ccccc5)cn(-c5ccccc5)c4=O)nc3)c2cc1OC Show InChI InChI=1S/C35H28N4O5/c1-42-31-19-27-29(20-32(31)43-2)36-16-15-30(27)44-26-13-14-33(37-21-26)38-34(40)28-18-24(17-23-9-5-3-6-10-23)22-39(35(28)41)25-11-7-4-8-12-25/h3-16,18-22H,17H2,1-2H3,(H,37,38,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367441 (CHEMBL8268) Show SMILES Oc1cccc(c1)[C@H]1CCCNC1 Show InChI InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol | (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	417	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367446 (CHEMBL49617) Show SMILES CN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3/t11-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301367 (CHEMBL570381 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...) Show SMILES COc1ccc2c(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccnc4)nc3)ccnc2c1 Show InChI InChI=1S/C32H23N5O4/c1-40-24-9-11-26-28(17-24)34-15-13-29(26)41-25-10-12-30(35-19-25)36-31(38)27-16-22(21-6-5-14-33-18-21)20-37(32(27)39)23-7-3-2-4-8-23/h2-20H,1H3,(H,35,36,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367443 (CHEMBL45778) Show SMILES CCCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367442 (CHEMBL424223) Show SMILES CC(C)N1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367447 (CHEMBL47750) Show SMILES CCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367440 (CHEMBL48219) Show SMILES CCCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367446 (CHEMBL49617) Show SMILES CN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367444 (CHEMBL432125) Show SMILES CC(C)N1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367441 (CHEMBL8268) Show SMILES Oc1cccc(c1)[C@H]1CCCNC1 Show InChI InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367442 (CHEMBL424223) Show SMILES CC(C)N1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010617 ((-)-3-(1-Propyl-piperidin-3-yl)-phenol | (S)-3-(1-...) Show SMILES CCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	810	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367447 (CHEMBL47750) Show SMILES CCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Jak3				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301368 (CHEMBL570189 | N-(5-(7-methoxyquinolin-4-yloxy)pyr...) Show SMILES COc1ccc2c(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cnccn4)nc3)ccnc2c1 Show InChI InChI=1S/C31H22N6O4/c1-40-22-7-9-24-26(16-22)33-12-11-28(24)41-23-8-10-29(35-17-23)36-30(38)25-15-20(27-18-32-13-14-34-27)19-37(31(25)39)21-5-3-2-4-6-21/h2-19H,1H3,(H,35,36,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Eukaryotic translation initiation factor 2-alpha kinase 3 (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PEK				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Jak1				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Jak2				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Interferon-induced, double-stranded RNA-activated protein kinase (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of PKR				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human))	BDBM50301356 (CHEMBL585927 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES CNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C29H25N5O5/c1-30-21-12-14-34(18-7-5-4-6-8-18)29(36)27(21)28(35)33-26-10-9-19(17-32-26)39-23-11-13-31-22-16-25(38-3)24(37-2)15-20(22)23/h4-17,30H,1-3H3,(H,32,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of TYK2				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367444 (CHEMBL432125) Show SMILES CC(C)N1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301364 (CHEMBL570380 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(cn(-c5ccccc5)c4=O)-c4cccs4)nc3)c2cc1OC Show InChI InChI=1S/C32H24N4O5S/c1-39-27-16-23-25(17-28(27)40-2)33-13-12-26(23)41-22-10-11-30(34-18-22)35-31(37)24-15-20(29-9-6-14-42-29)19-36(32(24)38)21-7-4-3-5-8-21/h3-19H,1-2H3,(H,34,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human PyK2 Y402 autophosphorylation expressed in 293T cells by immunofluorescence assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50452348 (CHEMBL8033) Show SMILES Oc1cccc(c1)[C@@H]1CCCNC1 Show InChI InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50301359 (CHEMBL570846 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4c(NC5CCOCC5)ccn(-c5ccccc5)c4=O)nc3)c2cc1OC Show InChI InChI=1S/C33H31N5O6/c1-41-28-18-24-26(19-29(28)42-2)34-14-10-27(24)44-23-8-9-30(35-20-23)37-32(39)31-25(36-21-12-16-43-17-13-21)11-15-38(33(31)40)22-6-4-3-5-7-22/h3-11,14-15,18-21,36H,12-13,16-17H2,1-2H3,(H,35,37,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAK by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50453368 (CHEMBL47900) Show SMILES CCc1ccc(cc1)N1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C19H23NO/c1-2-15-8-10-18(11-9-15)20-12-4-6-17(14-20)16-5-3-7-19(21)13-16/h3,5,7-11,13,17,21H,2,4,6,12,14H2,1H3/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM50301361 (CHEMBL570647 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4c(Nc5ccccc5)ccn(-c5ccccc5)c4=O)nc3)c2cc1OC Show InChI InChI=1S/C34H27N5O5/c1-42-29-19-25-27(20-30(29)43-2)35-17-15-28(25)44-24-13-14-31(36-21-24)38-33(40)32-26(37-22-9-5-3-6-10-22)16-18-39(34(32)41)23-11-7-4-8-12-23/h3-21,37H,1-2H3,(H,36,38,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human Pyk2 by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367440 (CHEMBL48219) Show SMILES CCCCN1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50010618 ((+)-3-(1-Propyl-piperidin-3-yl)-phenol | 3-((R)-1-...) Show SMILES CCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50301366 (5-benzyl-N-(5-(6,7-dimethoxyquinolin-4-yloxy)pyrid...) Show SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4cc(Cc5ccccc5)cn(-c5ccccc5)c4=O)nc3)c2cc1OC Show InChI InChI=1S/C35H28N4O5/c1-42-31-19-27-29(20-32(31)43-2)36-16-15-30(27)44-26-13-14-33(37-21-26)38-34(40)28-18-24(17-23-9-5-3-6-10-23)22-39(35(28)41)25-11-7-4-8-12-25/h3-16,18-22H,17H2,1-2H3,(H,37,38,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAK by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50301358 (CHEMBL568729 | N-(5-(6,7-dimethoxyquinolin-4-yloxy...) Show SMILES COCCNc1ccn(-c2ccccc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)cn1 Show InChI InChI=1S/C31H29N5O6/c1-39-16-14-33-23-12-15-36(20-7-5-4-6-8-20)31(38)29(23)30(37)35-28-10-9-21(19-34-28)42-25-11-13-32-24-18-27(41-3)26(40-2)17-22(24)25/h4-13,15,17-19,33H,14,16H2,1-3H3,(H,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human FAK by HTRF assay				Bioorg Med Chem Lett 19: 4924-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.084 BindingDB Entry DOI: 10.7270/Q2N017G2
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50453368 (CHEMBL47900) Show SMILES CCc1ccc(cc1)N1CCC[C@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C19H23NO/c1-2-15-8-10-18(11-9-15)20-12-4-6-17(14-20)16-5-3-7-19(21)13-16/h3,5,7-11,13,17,21H,2,4,6,12,14H2,1H3/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair

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