Compile Data Set for Download or QSAR

Found 164 hits with Last Name = 'sander' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50247053 (1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine ...) Show SMILES Clc1ccc(CCCOCCCN2CCCCC2)cc1 Show InChI InChI=1S/C17H26ClNO/c18-17-9-7-16(8-10-17)6-4-14-20-15-5-13-19-11-2-1-3-12-19/h7-10H,1-6,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327232 (4,5-diphenyl-2-(3-(piperidin-1-yl)propoxy)thiazole...) Show SMILES C(COc1nc(c(s1)-c1ccccc1)-c1ccccc1)CN1CCCCC1 Show InChI InChI=1S/C23H26N2OS/c1-4-11-19(12-5-1)21-22(20-13-6-2-7-14-20)27-23(24-21)26-18-10-17-25-15-8-3-9-16-25/h1-2,4-7,11-14H,3,8-10,15-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304523 (CHEMBL595180 | N4-(2,6-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2c(Cl)cccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-5-7-24(8-6-23)15-9-14(21-16(19)22-15)20-10-11-12(17)3-2-4-13(11)18/h2-4,9H,5-8,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327314 (5-ethyl-2-(3-(piperidin-1-yl)propoxy)-4,5,6,7-tetr...) Show SMILES CCN1CCc2sc(OCCCN3CCCCC3)nc2C1 Show InChI InChI=1S/C16H27N3OS/c1-2-18-11-7-15-14(13-18)17-16(21-15)20-12-6-10-19-8-4-3-5-9-19/h2-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304524 (CHEMBL594721 | N4-(2-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-4-2-3-5-13(12)17/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327316 (2-(3-(piperidin-1-yl)propoxy)-5-(3-(piperidin-1-yl...) Show SMILES C(COc1nc2CN(CCCN3CCCCC3)CCc2s1)CN1CCCCC1 Show InChI InChI=1S/C22H38N4OS/c1-3-10-24(11-4-1)14-7-15-26-17-9-21-20(19-26)23-22(28-21)27-18-8-16-25-12-5-2-6-13-25/h1-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327313 (5-methyl-2-(3-(piperidin-1-yl)propoxy)-4,5,6,7-tet...) Show SMILES CN1CCc2sc(OCCCN3CCCCC3)nc2C1 Show InChI InChI=1S/C15H25N3OS/c1-17-10-6-14-13(12-17)16-15(20-14)19-11-5-9-18-7-3-2-4-8-18/h2-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304525 (CHEMBL594731 | N4-(2-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2C)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-5-3-4-6-14(13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327320 (4-methyl-5-phenyl-2-(3-(piperidin-1-yl)propoxy)thi...) Show SMILES Cc1nc(OCCCN2CCCCC2)sc1-c1ccccc1 Show InChI InChI=1S/C18H24N2OS/c1-15-17(16-9-4-2-5-10-16)22-18(19-15)21-14-8-13-20-11-6-3-7-12-20/h2,4-5,9-10H,3,6-8,11-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304528 (CHEMBL593103 | N4-(4-Fluorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(F)cc2)nc(N)n1 Show InChI InChI=1S/C16H21FN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304526 (CHEMBL594022 | N4-(4-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(Cl)cc2)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327319 (4-bromo-5-phenyl-2-(3-(piperidin-1-yl)propoxy)thia...) Show SMILES Brc1nc(OCCCN2CCCCC2)sc1-c1ccccc1 Show InChI InChI=1S/C17H21BrN2OS/c18-16-15(14-8-3-1-4-9-14)22-17(19-16)21-13-7-12-20-10-5-2-6-11-20/h1,3-4,8-9H,2,5-7,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304527 (CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2)nc(N)n1 Show InChI InChI=1S/C16H22N6/c1-21-7-9-22(10-8-21)15-11-14(19-16(17)20-15)18-12-13-5-3-2-4-6-13/h2-6,11H,7-10,12H2,1H3,(H3,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304503 (4-(3,4-Dihydroisoquinolin-2(1H)-yl)-6-(4-methylpip...) Show SMILES CN1CCN(CC1)c1cc(nc(N)n1)N1CCc2ccccc2C1 Show InChI InChI=1S/C18H24N6/c1-22-8-10-23(11-9-22)16-12-17(21-18(19)20-16)24-7-6-14-4-2-3-5-15(14)13-24/h2-5,12H,6-11,13H2,1H3,(H2,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304529 (CHEMBL595215 | N4-(3,4-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(Cl)c(Cl)c2)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-4-6-24(7-5-23)15-9-14(21-16(19)22-15)20-10-11-2-3-12(17)13(18)8-11/h2-3,8-9H,4-7,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327312 (2-(3-(dimethylamino)propoxy)-6,7-dihydrobenzo[d]th...) Show SMILES CN(C)CCCOc1nc2c(CCCC2=O)s1 Show InChI InChI=1S/C12H18N2O2S/c1-14(2)7-4-8-16-12-13-11-9(15)5-3-6-10(11)17-12/h3-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	153	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327321 (1-(5-methyl-2-(3-(piperidin-1-yl)propoxy)thiazol-4...) Show SMILES CC(=O)c1nc(OCCCN2CCCCC2)sc1C Show InChI InChI=1S/C14H22N2O2S/c1-11(17)13-12(2)19-14(15-13)18-10-6-9-16-7-4-3-5-8-16/h3-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304530 (CHEMBL609161 | N4-(4-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(C)cc2)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-3-5-14(6-4-13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304500 (4-((2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(O)cc2)nc(N)n1 Show InChI InChI=1S/C16H22N6O/c1-21-6-8-22(9-7-21)15-10-14(19-16(17)20-15)18-11-12-2-4-13(23)5-3-12/h2-5,10,23H,6-9,11H2,1H3,(H3,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	237	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304502 (4-(isoindolin-2-yl)-6-(4-methylpiperazin-1-yl)pyri...) Show SMILES CN1CCN(CC1)c1cc(nc(N)n1)N1Cc2ccccc2C1 Show InChI InChI=1S/C17H22N6/c1-21-6-8-22(9-7-21)15-10-16(20-17(18)19-15)23-11-13-4-2-3-5-14(13)12-23/h2-5,10H,6-9,11-12H2,1H3,(H2,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327309 (CHEMBL1255715 | N,N-dimethyl-3-(5-methyl-4,5,6,7-t...) Show SMILES CN(C)CCCOc1nc2CN(C)CCc2s1 Show InChI InChI=1S/C12H21N3OS/c1-14(2)6-4-8-16-12-13-10-9-15(3)7-5-11(10)17-12/h4-9H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327315 (5-benzyl-2-(3-(piperidin-1-yl)propoxy)-4,5,6,7-tet...) Show SMILES C(COc1nc2CN(Cc3ccccc3)CCc2s1)CN1CCCCC1 Show InChI InChI=1S/C21H29N3OS/c1-3-8-18(9-4-1)16-24-14-10-20-19(17-24)22-21(26-20)25-15-7-13-23-11-5-2-6-12-23/h1,3-4,8-9H,2,5-7,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	261	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304505 (CHEMBL594949 | N4-(3-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2cccc(C)c2)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-4-3-5-14(10-13)12-19-15-11-16(21-17(18)20-15)23-8-6-22(2)7-9-23/h3-5,10-11H,6-9,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304531 (CHEMBL595639 | N4-(3-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2cccc(Cl)c2)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-5-7-23(8-6-22)15-10-14(20-16(18)21-15)19-11-12-3-2-4-13(17)9-12/h2-4,9-10H,5-8,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304501 (6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine |...) Show SMILES CN1CCN(CC1)c1cc(N)nc(N)n1 Show InChI InChI=1S/C9H16N6/c1-14-2-4-15(5-3-14)8-6-7(10)12-9(11)13-8/h6H,2-5H2,1H3,(H4,10,11,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304504 (4-((2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(cc2)C#N)nc(N)n1 Show InChI InChI=1S/C17H21N7/c1-23-6-8-24(9-7-23)16-10-15(21-17(19)22-16)20-12-14-4-2-13(11-18)3-5-14/h2-5,10H,6-9,12H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	341	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327318 (2-(3-(piperidin-1-yl)propoxy)-6,7-dihydro-4H-pyran...) Show SMILES C(COc1nc2COCCc2s1)CN1CCCCC1 Show InChI InChI=1S/C14H22N2O2S/c1-2-6-16(7-3-1)8-4-9-18-14-15-12-11-17-10-5-13(12)19-14/h1-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	344	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327317 (2-(3-(piperidin-1-yl)propoxy)-4,5,6,7-tetrahydrobe...) Show SMILES C(COc1nc2CCCCc2s1)CN1CCCCC1 Show InChI InChI=1S/C15H24N2OS/c1-4-9-17(10-5-1)11-6-12-18-15-16-13-7-2-3-8-14(13)19-15/h1-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	357	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304507 (CHEMBL596562 | N-Benzyl-6-(4-methylpiperazin-1-yl)...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2)ncn1 Show InChI InChI=1S/C16H21N5/c1-20-7-9-21(10-8-20)16-11-15(18-13-19-16)17-12-14-5-3-2-4-6-14/h2-6,11,13H,7-10,12H2,1H3,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	417	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304506 (6-(4-Methylpiperazin-1-yl)-N4-(3-nitrobenzyl)pyrim...) Show SMILES CN1CCN(CC1)c1cc(NCc2cccc(c2)[N+]([O-])=O)nc(N)n1 Show InChI InChI=1S/C16H21N7O2/c1-21-5-7-22(8-6-21)15-10-14(19-16(17)20-15)18-11-12-3-2-4-13(9-12)23(24)25/h2-4,9-10H,5-8,11H2,1H3,(H3,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	538	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304509 (CHEMBL608717 | N4-(4-Methoxybenzyl)-6-(4-methylpip...) Show SMILES COc1ccc(CNc2cc(nc(N)n2)N2CCN(C)CC2)cc1 Show InChI InChI=1S/C17H24N6O/c1-22-7-9-23(10-8-22)16-11-15(20-17(18)21-16)19-12-13-3-5-14(24-2)6-4-13/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	542	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304508 (CHEMBL593551 | N4-(Biphenyl-4-ylmethyl)-6-(4-methy...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(cc2)-c2ccccc2)nc(N)n1 Show InChI InChI=1S/C22H26N6/c1-27-11-13-28(14-12-27)21-15-20(25-22(23)26-21)24-16-17-7-9-19(10-8-17)18-5-3-2-4-6-18/h2-10,15H,11-14,16H2,1H3,(H3,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	716	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304528 (CHEMBL593103 | N4-(4-Fluorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(F)cc2)nc(N)n1 Show InChI InChI=1S/C16H21FN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304523 (CHEMBL595180 | N4-(2,6-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2c(Cl)cccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-5-7-24(8-6-23)15-9-14(21-16(19)22-15)20-10-11-12(17)3-2-4-13(11)18/h2-4,9H,5-8,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304525 (CHEMBL594731 | N4-(2-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2C)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-5-3-4-6-14(13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304524 (CHEMBL594721 | N4-(2-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-4-2-3-5-13(12)17/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304523 (CHEMBL595180 | N4-(2,6-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2c(Cl)cccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-5-7-24(8-6-23)15-9-14(21-16(19)22-15)20-10-11-12(17)3-2-4-13(11)18/h2-4,9H,5-8,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304528 (CHEMBL593103 | N4-(4-Fluorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(F)cc2)nc(N)n1 Show InChI InChI=1S/C16H21FN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304525 (CHEMBL594731 | N4-(2-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2C)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-5-3-4-6-14(13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304524 (CHEMBL594721 | N4-(2-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-4-2-3-5-13(12)17/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327322 (2-(3-(piperidin-1-yl)propoxy)-6,7-dihydrobenzo[d]t...) Show SMILES O=C1CCCc2sc(OCCCN3CCCCC3)nc12 Show InChI InChI=1S/C15H22N2O2S/c18-12-6-4-7-13-14(12)16-15(20-13)19-11-5-10-17-8-2-1-3-9-17/h1-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327311 (3-(6,7-dihydro-4H-pyrano[3,4-d]thiazol-2-yloxy)-N,...) Show SMILES CN(C)CCCOc1nc2COCCc2s1 Show InChI InChI=1S/C11H18N2O2S/c1-13(2)5-3-6-15-11-12-9-8-14-7-4-10(9)16-11/h3-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50327310 (CHEMBL1255716 | N,N-dimethyl-3-(4,5,6,7-tetrahydro...) Show SMILES CN(C)CCCOc1nc2CCCCc2s1 Show InChI InChI=1S/C12H20N2OS/c1-14(2)8-5-9-15-12-13-10-6-3-4-7-11(10)16-12/h3-9H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe University Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan human histamine H3 receptor				Bioorg Med Chem Lett 20: 5879-82 (2010) Article DOI: 10.1016/j.bmcl.2010.07.098 BindingDB Entry DOI: 10.7270/Q2KH0NJ3
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304519 (6-(4-Methylpiperazin-1-yl)-N4-(4-(trifluoromethyl)...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(cc2)C(F)(F)F)nc(N)n1 Show InChI InChI=1S/C17H21F3N6/c1-25-6-8-26(9-7-25)15-10-14(23-16(21)24-15)22-11-12-2-4-13(5-3-12)17(18,19)20/h2-5,10H,6-9,11H2,1H3,(H3,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304521 (CHEMBL610626 | N4-(4-Isopropylbenzyl)-6-(4-methylp...) Show SMILES CC(C)c1ccc(CNc2cc(nc(N)n2)N2CCN(C)CC2)cc1 Show InChI InChI=1S/C19H28N6/c1-14(2)16-6-4-15(5-7-16)13-21-17-12-18(23-19(20)22-17)25-10-8-24(3)9-11-25/h4-7,12,14H,8-11,13H2,1-3H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304517 (4-(Benzyloxy)-6-(4-methylpiperazin-1-yl)pyrimidin-...) Show SMILES CN1CCN(CC1)c1cc(OCc2ccccc2)nc(N)n1 Show InChI InChI=1S/C16H21N5O/c1-20-7-9-21(10-8-20)14-11-15(19-16(17)18-14)22-12-13-5-3-2-4-6-13/h2-6,11H,7-10,12H2,1H3,(H2,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304520 (CHEMBL608864 | N4-(4-tert-Butylbenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(cc2)C(C)(C)C)nc(N)n1 Show InChI InChI=1S/C20H30N6/c1-20(2,3)16-7-5-15(6-8-16)14-22-17-13-18(24-19(21)23-17)26-11-9-25(4)10-12-26/h5-8,13H,9-12,14H2,1-4H3,(H3,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304510 (3-(4-chlorobenzyl)-7-(4-methylpiperazin-1-yl)-3H-[...) Show SMILES CN1CCN(CC1)c1ncnc2n(Cc3ccc(Cl)cc3)nnc12 Show InChI InChI=1S/C16H18ClN7/c1-22-6-8-23(9-7-22)15-14-16(19-11-18-15)24(21-20-14)10-12-2-4-13(17)5-3-12/h2-5,11H,6-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304511 (6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyr...) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(C)CC1 Show InChI InChI=1S/C13H18N4S/c1-3-10-8-11-12(14-9-15-13(11)18-10)17-6-4-16(2)5-7-17/h8-9H,3-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair

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