Compile Data Set for Download or QSAR

Found 128 hits with Last Name = 'sutton' and Initial = 'sw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50159110 (1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...) Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1 Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.970	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293202 ((S)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293199 (4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy...) Show SMILES C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O2/c1-2-6-19(5-1)23-13-14-24-21(16-23)17-25-20-9-7-18(8-10-20)15-22-11-3-4-12-22/h7-10,19,21H,1-6,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293200 (4-cyclopentyl-2-((4-(piperidin-1-ylmethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C22H34N2O2/c1-4-12-23(13-5-1)16-19-8-10-21(11-9-19)26-18-22-17-24(14-15-25-22)20-6-2-3-7-20/h8-11,20,22H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293189 (4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412863 (CHEMBL359632 | JNJ-10397049) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccc(Br)cc2Br)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H20Br2N2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412861 (CHEMBL185088) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccc(Br)cc2Cl)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H20BrClN2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293202 ((S)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293199 (4-cyclopentyl-2-((4-(pyrrolidin-1-ylmethyl)phenoxy...) Show SMILES C(Oc1ccc(CN2CCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O2/c1-2-6-19(5-1)23-13-14-24-21(16-23)17-25-20-9-7-18(8-10-20)15-22-11-3-4-12-22/h7-10,19,21H,1-6,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293200 (4-cyclopentyl-2-((4-(piperidin-1-ylmethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCCCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C22H34N2O2/c1-4-12-23(13-5-1)16-19-8-10-21(11-9-19)26-18-22-17-24(14-15-25-22)20-6-2-3-7-20/h8-11,20,22H,1-7,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293188 (4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-2-18(3-1)22-10-13-24-20(15-22)16-25-19-6-4-17(5-7-19)14-21-8-11-23-12-9-21/h4-7,18,20H,1-3,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293189 (4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCCC1 Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412862 (CHEMBL185136) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccc(Cl)cc2Cl)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H20Cl2N2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474855 (CHEMBL364814) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2ccccc2Cl)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C25H25ClN2O3/c1-25(2)30-16-22(23(31-25)17-10-4-3-5-11-17)28-24(29)27-21-15-9-7-13-19(21)18-12-6-8-14-20(18)26/h3-15,22-23H,16H2,1-2H3,(H2,27,28,29)/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293201 ((R)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293192 (4-cyclobutyl-2-((3-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-3-17(14-21-7-10-23-11-8-21)13-19(6-1)25-16-20-15-22(9-12-24-20)18-4-2-5-18/h1,3,6,13,18,20H,2,4-5,7-12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412860 (CHEMBL185093) Show SMILES Cc1cc(Br)ccc1NC(=O)N[C@H]1COC(C)(C)O[C@H]1c1ccccc1 |r| Show InChI InChI=1S/C20H23BrN2O3/c1-13-11-15(21)9-10-16(13)22-19(24)23-17-12-25-20(2,3)26-18(17)14-7-5-4-6-8-14/h4-11,17-18H,12H2,1-3H3,(H2,22,23,24)/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293187 (4-isopropyl-2-((4-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2ccc(CN3CCOCC3)cc2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-9-12-23-19(14-21)15-24-18-5-3-17(4-6-18)13-20-7-10-22-11-8-20/h3-6,16,19H,7-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474849 (CHEMBL185424) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2cccs2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C23H24N2O3S/c1-23(2)27-15-19(21(28-23)16-9-4-3-5-10-16)25-22(26)24-18-12-7-6-11-17(18)20-13-8-14-29-20/h3-14,19,21H,15H2,1-2H3,(H2,24,25,26)/t19-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412859 (CHEMBL182473) Show SMILES Cc1ccc(Cl)c(NC(=O)N[C@H]2COC(C)(C)O[C@H]2c2ccccc2)c1 |r| Show InChI InChI=1S/C20H23ClN2O3/c1-13-9-10-15(21)16(11-13)22-19(24)23-17-12-25-20(2,3)26-18(17)14-7-5-4-6-8-14/h4-11,17-18H,12H2,1-3H3,(H2,22,23,24)/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412857 (CHEMBL361716) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2cc(Cl)ccc2Cl)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H20Cl2N2O3/c1-19(2)25-11-16(17(26-19)12-6-4-3-5-7-12)23-18(24)22-15-10-13(20)8-9-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,24)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293188 (4-cyclobutyl-2-((4-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-2-18(3-1)22-10-13-24-20(15-22)16-25-19-6-4-17(5-7-19)14-21-8-11-23-12-9-21/h4-7,18,20H,1-3,8-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412855 (CHEMBL185382) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2I)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H21IN2O3/c1-19(2)24-12-16(17(25-19)13-8-4-3-5-9-13)22-18(23)21-15-11-7-6-10-14(15)20/h3-11,16-17H,12H2,1-2H3,(H2,21,22,23)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474846 (CHEMBL185131) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2cccc(Cl)c2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C25H25ClN2O3/c1-25(2)30-16-22(23(31-25)17-9-4-3-5-10-17)28-24(29)27-21-14-7-6-13-20(21)18-11-8-12-19(26)15-18/h3-15,22-23H,16H2,1-2H3,(H2,27,28,29)/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412854 (CHEMBL185435) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2Cl)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H21ClN2O3/c1-19(2)24-12-16(17(25-19)13-8-4-3-5-9-13)22-18(23)21-15-11-7-6-10-14(15)20/h3-11,16-17H,12H2,1-2H3,(H2,21,22,23)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474848 (CHEMBL184596) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2ccsc2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C23H24N2O3S/c1-23(2)27-14-20(21(28-23)16-8-4-3-5-9-16)25-22(26)24-19-11-7-6-10-18(19)17-12-13-29-15-17/h3-13,15,20-21H,14H2,1-2H3,(H2,24,25,26)/t20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293187 (4-isopropyl-2-((4-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2ccc(CN3CCOCC3)cc2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-9-12-23-19(14-21)15-24-18-5-3-17(4-6-18)13-20-7-10-22-11-8-20/h3-6,16,19H,7-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412851 (CHEMBL363951) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2C(F)(F)F)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C20H21F3N2O3/c1-19(2)27-12-16(17(28-19)13-8-4-3-5-9-13)25-18(26)24-15-11-7-6-10-14(15)20(21,22)23/h3-11,16-17H,12H2,1-2H3,(H2,24,25,26)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474847 (CHEMBL183421) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2ccccc2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C25H26N2O3/c1-25(2)29-17-22(23(30-25)19-13-7-4-8-14-19)27-24(28)26-21-16-10-9-15-20(21)18-11-5-3-6-12-18/h3-16,22-23H,17H2,1-2H3,(H2,26,27,28)/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412849 (CHEMBL363743) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2Br)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H21BrN2O3/c1-19(2)24-12-16(17(25-19)13-8-4-3-5-9-13)22-18(23)21-15-11-7-6-10-14(15)20/h3-11,16-17H,12H2,1-2H3,(H2,21,22,23)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293191 (4-isopropyl-2-((3-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2cccc(CN3CCOCC3)c2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-8-11-23-19(14-21)15-24-18-5-3-4-17(12-18)13-20-6-9-22-10-7-20/h3-5,12,16,19H,6-11,13-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293185 (4-cyclopropyl-2-((4-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)C1CN(CCO1)C1CC1 Show InChI InChI=1S/C19H28N2O3/c1-5-18(6-2-16(1)13-20-7-10-22-11-8-20)24-15-19-14-21(9-12-23-19)17-3-4-17/h1-2,5-6,17,19H,3-4,7-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293201 ((R)-4-cyclopentyl-2-((4-(morpholinomethyl)phenoxy)...) Show SMILES C(Oc1ccc(CN2CCOCC2)cc1)[C@H]1CN(CCO1)C1CCCC1 |r| Show InChI InChI=1S/C21H32N2O3/c1-2-4-19(3-1)23-11-14-25-21(16-23)17-26-20-7-5-18(6-8-20)15-22-9-12-24-13-10-22/h5-8,19,21H,1-4,9-17H2/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412858 (CHEMBL183576) Show SMILES Cc1ccc(NC(=O)N[C@H]2COC(C)(C)O[C@H]2c2ccccc2)c(C)c1 |r| Show InChI InChI=1S/C21H26N2O3/c1-14-10-11-17(15(2)12-14)22-20(24)23-18-13-25-21(3,4)26-19(18)16-8-6-5-7-9-16/h5-12,18-19H,13H2,1-4H3,(H2,22,23,24)/t18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50474855 (CHEMBL364814) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2ccccc2Cl)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C25H25ClN2O3/c1-25(2)30-16-22(23(31-25)17-10-4-3-5-11-17)28-24(29)27-21-15-9-7-13-19(21)18-12-6-8-14-20(18)26/h3-15,22-23H,16H2,1-2H3,(H2,27,28,29)/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 1 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293184 (4-ethyl-2-((4-(morpholinomethyl)phenoxy)methyl)mor...) Show SMILES CCN1CCOC(COc2ccc(CN3CCOCC3)cc2)C1 Show InChI InChI=1S/C18H28N2O3/c1-2-19-9-12-22-18(14-19)15-23-17-5-3-16(4-6-17)13-20-7-10-21-11-8-20/h3-6,18H,2,7-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	165	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474850 (CHEMBL185324) Show SMILES CC1(C)OC[C@H](NC(=O)c2ccc(Cl)cc2Cl)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C19H19Cl2NO3/c1-19(2)24-11-16(17(25-19)12-6-4-3-5-7-12)22-18(23)14-9-8-13(20)10-15(14)21/h3-10,16-17H,11H2,1-2H3,(H,22,23)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474844 (CHEMBL183734) Show SMILES CC1(C)OC[C@H](\N=C(/S)Nc2ccc(Cl)cc2Cl)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C19H20Cl2N2O2S/c1-19(2)24-11-16(17(25-19)12-6-4-3-5-7-12)23-18(26)22-15-9-8-13(20)10-14(15)21/h3-10,16-17H,11H2,1-2H3,(H2,22,23,26)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412864 (CHEMBL184936) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccc(Br)cc2)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H21BrN2O3/c1-19(2)24-12-16(17(25-19)13-6-4-3-5-7-13)22-18(23)21-15-10-8-14(20)9-11-15/h3-11,16-17H,12H2,1-2H3,(H2,21,22,23)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293192 (4-cyclobutyl-2-((3-(morpholinomethyl)phenoxy)methy...) Show SMILES C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CCC1 Show InChI InChI=1S/C20H30N2O3/c1-3-17(14-21-7-10-23-11-8-21)13-19(6-1)25-16-20-15-22(9-12-24-20)18-4-2-5-18/h1,3,6,13,18,20H,2,4-5,7-12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	277	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474845 (CHEMBL182269) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2cccnc2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C24H25N3O3/c1-24(2)29-16-21(22(30-24)17-9-4-3-5-10-17)27-23(28)26-20-13-7-6-12-19(20)18-11-8-14-25-15-18/h3-15,21-22H,16H2,1-2H3,(H2,26,27,28)/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50474854 (CHEMBL184303) Show SMILES CC1(C)OC[C@H](\N=C(/S)Nc2ccccc2Br)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C19H21BrN2O2S/c1-19(2)23-12-16(17(24-19)13-8-4-3-5-9-13)22-18(25)21-15-11-7-6-10-14(15)20/h3-11,16-17H,12H2,1-2H3,(H2,21,22,25)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412853 (CHEMBL361748) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2F)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H21FN2O3/c1-19(2)24-12-16(17(25-19)13-8-4-3-5-9-13)22-18(23)21-15-11-7-6-10-14(15)20/h3-11,16-17H,12H2,1-2H3,(H2,21,22,23)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412866 (CHEMBL360377) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H22N2O3/c1-19(2)23-13-16(17(24-19)14-9-5-3-6-10-14)21-18(22)20-15-11-7-4-8-12-15/h3-12,16-17H,13H2,1-2H3,(H2,20,21,22)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50474847 (CHEMBL183421) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2ccccc2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C25H26N2O3/c1-25(2)29-17-22(23(30-25)19-13-7-4-8-14-19)27-24(28)26-21-16-10-9-15-20(21)18-11-5-3-6-12-18/h3-16,22-23H,17H2,1-2H3,(H2,26,27,28)/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 1 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50474846 (CHEMBL185131) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2cccc(Cl)c2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C25H25ClN2O3/c1-25(2)30-16-22(23(31-25)17-9-4-3-5-10-17)28-24(29)27-21-14-7-6-13-20(21)18-11-8-12-19(26)15-18/h3-15,22-23H,16H2,1-2H3,(H2,27,28,29)/t22-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 1 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50293191 (4-isopropyl-2-((3-(morpholinomethyl)phenoxy)methyl...) Show SMILES CC(C)N1CCOC(COc2cccc(CN3CCOCC3)c2)C1 Show InChI InChI=1S/C19H30N2O3/c1-16(2)21-8-11-23-19(14-21)15-24-18-5-3-4-17(12-18)13-20-6-9-22-10-7-20/h3-5,12,16,19H,6-11,13-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from rat recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50293190 (4-cyclopropyl-2-((3-(morpholinomethyl)phenoxy)meth...) Show SMILES C(Oc1cccc(CN2CCOCC2)c1)C1CN(CCO1)C1CC1 Show InChI InChI=1S/C19H28N2O3/c1-2-16(13-20-6-9-22-10-7-20)12-18(3-1)24-15-19-14-21(8-11-23-19)17-4-5-17/h1-3,12,17,19H,4-11,13-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	566	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human recombinant histamine H3 receptor expressed in human SK-N-MC cells				Bioorg Med Chem Lett 18: 5796-9 (2009) Article DOI: 10.1016/j.bmcl.2008.09.077 BindingDB Entry DOI: 10.7270/Q2154H28
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50412865 (CHEMBL185080) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2cccc(Br)c2)[C@@H](O1)c1ccccc1 |r| Show InChI InChI=1S/C19H21BrN2O3/c1-19(2)24-12-16(17(25-19)13-7-4-3-5-8-13)22-18(23)21-15-10-6-9-14(20)11-15/h3-11,16-17H,12H2,1-2H3,(H2,21,22,23)/t16-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM50474849 (CHEMBL185424) Show SMILES CC1(C)OC[C@H](NC(=O)Nc2ccccc2-c2cccs2)[C@@H](O1)c1ccccc1 Show InChI InChI=1S/C23H24N2O3S/c1-23(2)27-15-19(21(28-23)16-9-4-3-5-10-16)25-22(26)24-18-12-7-6-11-17(18)20-13-8-14-29-20/h3-14,19,21H,15H2,1-2H3,(H2,24,25,26)/t19-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Binding affinity towards human orexin receptor type 1 was determined using [125I]-Orexin A as radio ligand				Bioorg Med Chem Lett 14: 4225-9 (2004) Article DOI: 10.1016/j.bmcl.2004.06.032 BindingDB Entry DOI: 10.7270/Q2K64MV4
					More data for this Ligand-Target Pair

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