Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lanosterol synthase (Rattus norvegicus) | BDBM50180953 (CHEMBL3818719) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Caprotec Bioanalytics GmbH Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ... | J Med Chem 59: 4664-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01970 BindingDB Entry DOI: 10.7270/Q2WD42HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50108877 ((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
Caprotec Bioanalytics GmbH Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ... | J Med Chem 59: 4664-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01970 BindingDB Entry DOI: 10.7270/Q2WD42HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50180952 (CHEMBL3818350) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
Caprotec Bioanalytics GmbH Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ... | J Med Chem 59: 4664-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01970 BindingDB Entry DOI: 10.7270/Q2WD42HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50108879 ((2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 386 | n/a | n/a | n/a | n/a | n/a | n/a |
Caprotec Bioanalytics GmbH Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ... | J Med Chem 59: 4664-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01970 BindingDB Entry DOI: 10.7270/Q2WD42HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50180954 (CHEMBL3819488) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 648 | n/a | n/a | n/a | n/a | n/a | n/a |
Caprotec Bioanalytics GmbH Curated by ChEMBL | Assay Description Inhibition of human recombinant His-tagged soluble COMT expressed in Escherichia coli BL21 using aesculetin as substrate after 60 mins by microplate ... | J Med Chem 59: 4664-75 (2016) Article DOI: 10.1021/acs.jmedchem.5b01970 BindingDB Entry DOI: 10.7270/Q2WD42HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dynamin-1 (Homo sapiens (Human)) | BDBM50388829 (CHEMBL2062753) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re... | ACS Med Chem Lett 3: 352-356 (2012) Article DOI: 10.1021/ml200284s BindingDB Entry DOI: 10.7270/Q2V40W83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446548 (CHEMBL3110181) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dynamin-1 (Homo sapiens (Human)) | BDBM50388828 (CHEMBL2062743) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re... | ACS Med Chem Lett 3: 352-356 (2012) Article DOI: 10.1021/ml200284s BindingDB Entry DOI: 10.7270/Q2V40W83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446543 (CHEMBL3110178) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446549 (CHEMBL3110180) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446544 (CHEMBL3110188) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446542 (CHEMBL3110179) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446540 (CHEMBL3110184) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446546 (CHEMBL3110183) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446551 (CHEMBL3110174) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dynamin-1 (Homo sapiens (Human)) | BDBM50388827 (CHEMBL2062731) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re... | ACS Med Chem Lett 3: 352-356 (2012) Article DOI: 10.1021/ml200284s BindingDB Entry DOI: 10.7270/Q2V40W83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446547 (CHEMBL3110182) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446553 (CHEMBL3110161) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446552 (CHEMBL3110162) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dynamin-1 (Homo sapiens (Human)) | BDBM50388830 (CHEMBL2062756) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of dynamin1-mediated endocytosis in human U2OS cells assessed as inhibition of Texas red-Tf uptake incubated for 30 mins prior to Texas re... | ACS Med Chem Lett 3: 352-356 (2012) Article DOI: 10.1021/ml200284s BindingDB Entry DOI: 10.7270/Q2V40W83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446555 (CHEMBL3110160) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446545 (CHEMBL3110186) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446541 (CHEMBL3110185) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446550 (CHEMBL3110177) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446556 (CHEMBL3110158) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Clathrin heavy chain 1 (Homo sapiens (Human)) | BDBM50446554 (CHEMBL3110159) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Newcastle Curated by ChEMBL | Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA | J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT | |||||||||||
More data for this Ligand-Target Pair |