Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263346![]() (US9546162, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.300 | n/a | n/a | n/a | 11 | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description Cells were seeded at a density of 5×104 cells per well in Biocoat® Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) an... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179992![]() (US9676720, Example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179995![]() (US9676720, Example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.610 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50403532![]() (CHEMBL5285583) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | 0.630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Antagonist activity at NK-2 tachykinin receptors in rabbit pulmonary artery | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50101830![]() ((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Compound was evaluated for its competitive binding affinity towards human Prostanoid EP2 receptor in CHO cells expressing prostanoid receptor | Bioorg Med Chem Lett 11: 2025-8 (2001) BindingDB Entry DOI: 10.7270/Q2CV4H1T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180045![]() (US9676720, Comparative example 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179994![]() (US9676720, Example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179998![]() (US9676720, Example 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.790 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179996![]() (US9676720, Example 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179993![]() (US9676720, Example 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180000![]() (US9676720, Example 14) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179999![]() (US9676720, Example 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.940 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180002![]() (US9676720, Example 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM179997![]() (US9676720, Example 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180003![]() (US9676720, Example 18) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM35847![]() ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cayman Chemical Company, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human recombinant EP2 receptor expressed in HEK293 cell membranes after 120 mins by liquid scintillation counting metho... | J Med Chem 62: 4731-4741 (2019) Article DOI: 10.1021/acs.jmedchem.9b00336 BindingDB Entry DOI: 10.7270/Q22R3W32 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180020![]() (US9676720, Comparative example 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119438![]() (BDBM119693 | US8685986, 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.10 | -12.4 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180024![]() (US9676720, Comparative example 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180004![]() (US9676720, Example 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180019![]() (US9676720, Comparative example 7) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180005![]() (US9676720, Comparative example 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180021![]() (US9676720, Comparative example 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119442![]() (US8685986, 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.5 | -12.2 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180022![]() (US9676720, Comparative example 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50016952![]() (CHEMBL3286796) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to EP2 receptor (unknown origin) by competitive binding assay | J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119432![]() (US8685986, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 1.90 | -12.1 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263343![]() (US9546162, 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263347![]() (US9546162, 5) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2 | n/a | n/a | n/a | 11 | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180025![]() (US9676720, Comparative example 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180018![]() (US9676720, Comparative example 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180026![]() (US9676720, Comparative example 13) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119433![]() (US8685986, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 2.80 | -11.9 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263357![]() (US9546162, 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 3 | n/a | n/a | n/a | 11 | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119441![]() (US8685986, 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 3.10 | -11.8 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180038![]() (US9676720, Comparative example 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50101830![]() ((Z)-7-{(1R,2R,3R,5R)-5-Chloro-2-[(E)-(S)-4-(1-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to EP2 receptor (unknown origin) by competitive binding assay | J Med Chem 57: 4454-65 (2014) Article DOI: 10.1021/jm401431x BindingDB Entry DOI: 10.7270/Q2CR5VXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50506546![]() (Omidenepag | UR-7276) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180006![]() (US9676720, Comparative example 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119435![]() (US8685986, 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.80 | -11.7 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119437![]() (US8685986, 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.80 | -11.7 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM180007![]() (US9676720, Comparative example 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | 6.0 | n/a |
UBE INDUSTRIES, LTD. US Patent | Assay Description Measurement of EP2 receptor binding action was performed in accordance with the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285... | US Patent US9676720 (2017) BindingDB Entry DOI: 10.7270/Q2057D39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM119436![]() (US8685986, 9) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 4.40 | -11.6 | n/a | n/a | n/a | n/a | n/a | 6.0 | 30 |
Ube Industries, Ltd. US Patent | Assay Description Measurement of EP2 receptor binding affinity was carried out according to the method of Abramovitz et al. (Biochimica et Biophysica Acta, 1483, 285 (... | US Patent US8685986 (2014) BindingDB Entry DOI: 10.7270/Q28S4NK1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM35847![]() ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD Serono Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cells | Bioorg Med Chem Lett 17: 4323-7 (2007) Article DOI: 10.1016/j.bmcl.2007.05.025 BindingDB Entry DOI: 10.7270/Q2RF5VVC | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM35847![]() ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute, Inc. Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP2 receptor | Bioorg Med Chem Lett 18: 821-4 (2008) Article DOI: 10.1016/j.bmcl.2007.11.020 BindingDB Entry DOI: 10.7270/Q2W096SW | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM35847![]() ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
EMD-Serono Research Institute Curated by ChEMBL | Assay Description Binding affinity at human prostaglandin EP2 receptor | Bioorg Med Chem Lett 17: 6572-5 (2007) Article DOI: 10.1016/j.bmcl.2007.09.074 BindingDB Entry DOI: 10.7270/Q29887V9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM35847![]() ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by PDSP Ki Database | Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM263353![]() (US9546162, 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 6 | n/a | n/a | n/a | 13 | n/a | n/a | 7.4 | n/a |
ALLERGAN, INC. US Patent | Assay Description HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o... | US Patent US9546162 (2017) BindingDB Entry DOI: 10.7270/Q2P55QHV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM85603![]() (CAS_5311503 | NSC_5311503 | ZK110841) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by PDSP Ki Database | Biochim Biophys Acta 1483: 285-93 (2000) Article DOI: 10.1016/s1388-1981(99)00164-x BindingDB Entry DOI: 10.7270/Q2J964XQ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human)) | BDBM50142480![]() ((E)-7-[(1R,2S,3R)-3-Hydroxy-2-((E)-(S)-3-hydroxy-o...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Palo Alto Curated by ChEMBL | Assay Description Binding affinity was determined against prostanoid EP2 receptor | Bioorg Med Chem Lett 14: 1655-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.063 BindingDB Entry DOI: 10.7270/Q2MK6CBC | |||||||||||
More data for this Ligand-Target Pair |
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