Compile Data Set for Download or QSAR

Found 22 hits of ic50 for UniProtKB: P04637   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236279 (US9365576, 32) Show SMILES CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1C)c1cc(Cl)ccc1C |r| Show InChI InChI=1S/C32H31Cl2N3O3/c1-17(2)36-27(24-14-20(31(38)35-5)8-12-28(24)40-6)16-25-30(36)29(23-11-10-21(33)13-19(23)4)37(32(25)39)26-15-22(34)9-7-18(26)3/h7-17,29H,1-6H3,(H,35,38)/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236284 (US9365576, 37) Show SMILES COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)NOCCO Show InChI InChI=1S/C32H31Cl2N3O5/c1-18(2)36-27(24-15-21(8-12-28(24)41-4)31(39)35-42-14-13-38)17-25-30(36)29(20-6-10-22(33)11-7-20)37(32(25)40)26-16-23(34)9-5-19(26)3/h5-12,15-18,29,38H,13-14H2,1-4H3,(H,35,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	327	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236257 (US9365576, 10) Show SMILES CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C Show InChI InChI=1S/C31H29Cl2N3O3/c1-17(2)35-26(23-14-20(30(37)34-4)9-13-27(23)39-5)16-24-29(35)28(19-7-11-21(32)12-8-19)36(31(24)38)25-15-22(33)10-6-18(25)3/h6-17,28H,1-5H3,(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	478	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236254 (US9365576, 7) Show SMILES CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F |r| Show InChI InChI=1S/C31H28Cl2FN3O3/c1-16(2)36-25(21-14-18(30(38)35-4)9-12-26(21)40-5)15-22-29(36)28(20-11-10-19(32)13-17(20)3)37(31(22)39)24-8-6-7-23(33)27(24)34/h6-16,28H,1-5H3,(H,35,38)/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	508	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236414 (US9365576, 167) Show SMILES COc1nc(ncc1-c1cc2C(=O)N([C@H](c2n1C(C)C)c1ccc(cc1)C#N)c1cc(Cl)c[nH]c1=O)N(C)C |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	717	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236368 (US9365576, 121 | US9365576, 218) Show SMILES COc1ncc(-c2cc3C(=O)N([C@H](c3n2C(C)C)c2ccc(Cl)cc2)c2cc(Cl)c(=O)n(C)c2)c(OC)n1 |r| Show InChI InChI=1S/C27H25Cl2N5O4/c1-14(2)33-21(19-12-30-27(38-5)31-24(19)37-4)11-18-23(33)22(15-6-8-16(28)9-7-15)34(25(18)35)17-10-20(29)26(36)32(3)13-17/h6-14,22H,1-5H3/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236349 (US9365576, 102) Show SMILES CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)[C@H]1CC[C@H](O)CC1 |r,wU:35.39,wD:32.35,(8.91,-2.4,;8.14,-1.07,;6.6,-1.07,;5.83,-2.4,;5.83,.26,;6.6,1.6,;5.83,2.93,;4.29,2.93,;3.52,4.26,;4.29,5.6,;3.52,1.6,;4.29,.26,;1.98,1.6,;1.08,2.84,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-1.16,-2.22,;-1.56,-3.71,;-3.05,-4.11,;-3.44,-5.6,;-4.13,-3.02,;-3.74,-1.53,;-4.82,-.45,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-5.06,.26,)| Show InChI InChI=1S/C31H36ClN3O4/c1-17(2)34-26(24-15-19(30(37)33-4)6-13-27(24)39-5)16-25-29(34)28(23-12-7-20(32)14-18(23)3)35(31(25)38)21-8-10-22(36)11-9-21/h6-7,12-17,21-22,28,36H,8-11H2,1-5H3,(H,33,37)/t21-,22-,28?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236249 (US9365576, 2) Show SMILES CNC(=O)c1ccc(OC)c(c1)-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F Show InChI InChI=1S/C31H28Cl2FN3O3/c1-16(2)36-25(21-14-18(30(38)35-4)9-12-26(21)40-5)15-22-29(36)28(20-11-10-19(32)13-17(20)3)37(31(22)39)24-8-6-7-23(33)27(24)34/h6-16,28H,1-5H3,(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236348 (US9365576, 101) Show SMILES COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)[C@H]1CC[C@H](O)CC1 |r,wU:31.35,wD:28.31,(5.45,5.6,;4.68,4.26,;5.45,2.93,;6.99,2.93,;7.76,1.6,;6.99,.26,;5.45,.26,;4.68,1.6,;3.14,1.6,;2.23,2.84,;.77,2.37,;-.69,2.84,;-1.46,4.18,;-1.6,1.6,;-.69,.35,;.77,.83,;2.23,.35,;2.63,-1.14,;1.54,-2.22,;4.12,-1.53,;-1.09,-1.14,;-0,-2.22,;-.4,-3.71,;-1.89,-4.11,;-2.29,-5.6,;-2.98,-3.02,;-2.58,-1.53,;-3.67,-.45,;-3.14,1.6,;-3.91,2.93,;-5.45,2.93,;-6.22,1.6,;-7.76,1.6,;-5.45,.26,;-3.91,.26,)| Show InChI InChI=1S/C29H33ClN2O3/c1-17(2)31-25(23-7-5-6-8-26(23)35-4)16-24-28(31)27(22-14-9-19(30)15-18(22)3)32(29(24)34)20-10-12-21(33)13-11-20/h5-9,14-17,20-21,27,33H,10-13H2,1-4H3/t20-,21-,27?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236354 (US9365576, 107) Show SMILES CNC(=O)N1CCC(CC1)N1C(c2c(cc(-c3cnc(OC)nc3OC)n2C(C)C)C1=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H33ClN6O4/c1-16(2)34-22(21-15-31-27(39-5)32-25(21)38-4)14-20-24(34)23(17-6-8-18(29)9-7-17)35(26(20)36)19-10-12-33(13-11-19)28(37)30-3/h6-9,14-16,19,23H,10-13H2,1-5H3,(H,30,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.64E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236256 (US9365576, 9) Show SMILES COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C Show InChI InChI=1S/C29H26Cl2N2O2/c1-17(2)32-25(22-7-5-6-8-26(22)35-4)16-23-28(32)27(19-10-13-20(30)14-11-19)33(29(23)34)24-15-21(31)12-9-18(24)3/h5-17,27H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.03E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236350 (US9365576, 103) Show SMILES COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)[C@H]2CC[C@H](O)CC2)c(OC)n1 |r,wU:29.32,wD:26.28,(8.91,.26,;8.14,1.6,;6.6,1.6,;5.83,.26,;4.29,.26,;3.52,1.6,;1.98,1.6,;1.08,2.84,;-.38,2.37,;-1.85,2.84,;-2.62,4.18,;-2.75,1.6,;-1.85,.35,;-.38,.83,;1.08,.35,;1.48,-1.14,;.39,-2.22,;2.97,-1.53,;-2.25,-1.14,;-1.16,-2.22,;-1.56,-3.71,;-3.05,-4.11,;-3.44,-5.6,;-4.13,-3.02,;-3.74,-1.53,;-4.82,-.45,;-4.29,1.6,;-5.06,2.93,;-6.6,2.93,;-7.37,1.6,;-8.91,1.6,;-6.6,.26,;-5.06,.26,;4.29,2.93,;3.52,4.26,;4.29,5.6,;5.83,2.93,)| Show InChI InChI=1S/C28H33ClN4O4/c1-15(2)32-23(22-14-30-28(37-5)31-26(22)36-4)13-21-25(32)24(20-11-6-17(29)12-16(20)3)33(27(21)35)18-7-9-19(34)10-8-18/h6,11-15,18-19,24,34H,7-10H2,1-5H3/t18-,19-,24?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236352 (US9365576, 105) Show SMILES COc1ncc(-c2cc3C(=O)N(C(c3n2C(C)C)c2ccc(Cl)cc2C)C2CCOCC2)c(OC)n1 Show InChI InChI=1S/C27H31ClN4O4/c1-15(2)31-22(21-14-29-27(35-5)30-25(21)34-4)13-20-24(31)23(19-7-6-17(28)12-16(19)3)32(26(20)33)18-8-10-36-11-9-18/h6-7,12-15,18,23H,8-11H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236315 (US9365576, 68) Show SMILES COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1 |r,wU:31.35,wD:28.31,(4.68,5.6,;3.91,4.26,;4.68,2.93,;6.22,2.93,;6.99,1.6,;8.53,1.6,;6.22,.26,;4.68,.26,;3.91,1.6,;2.37,1.6,;1.46,2.84,;,2.37,;-1.46,2.84,;-2.23,4.18,;-2.37,1.6,;-1.46,.35,;,.83,;1.46,.35,;1.86,-1.14,;.77,-2.22,;3.35,-1.53,;-1.86,-1.14,;-3.35,-1.53,;-3.75,-3.02,;-2.66,-4.11,;-3.06,-5.6,;-1.17,-3.71,;-.77,-2.22,;-3.91,1.6,;-4.68,2.93,;-6.22,2.93,;-6.99,1.6,;-8.53,1.6,;-6.22,.26,;-4.68,.26,)| Show InChI InChI=1S/C26H30ClN5O3/c1-14(2)31-21(20-13-29-26(28)30-24(20)35-3)12-19-23(31)22(15-4-6-16(27)7-5-15)32(25(19)34)17-8-10-18(33)11-9-17/h4-7,12-14,17-18,22,33H,8-11H2,1-3H3,(H2,28,29,30)/t17-,18-,22?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.86E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236312 (US9365576, 65) Show SMILES COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1)C(O)=O |r,wU:30.34,wD:27.30,(4.68,5.6,;3.91,4.26,;4.68,2.93,;6.22,2.93,;6.99,1.6,;6.22,.26,;4.68,.26,;3.91,1.6,;2.37,1.6,;1.46,2.84,;,2.37,;-1.46,2.84,;-2.23,4.18,;-2.37,1.6,;-1.46,.35,;,.83,;1.46,.35,;1.86,-1.14,;.77,-2.22,;3.35,-1.53,;-1.86,-1.14,;-3.35,-1.53,;-3.75,-3.02,;-2.66,-4.11,;-3.06,-5.6,;-1.17,-3.71,;-.77,-2.22,;-3.91,1.6,;-4.68,2.93,;-6.22,2.93,;-6.99,1.6,;-8.53,1.6,;-6.22,.26,;-4.68,.26,;6.99,-1.07,;8.53,-1.07,;6.22,-2.4,)| Show InChI InChI=1S/C29H31ClN2O5/c1-16(2)31-24(22-14-18(29(35)36)6-13-25(22)37-3)15-23-27(31)26(17-4-7-19(30)8-5-17)32(28(23)34)20-9-11-21(33)12-10-20/h4-8,13-16,20-21,26,33H,9-12H2,1-3H3,(H,35,36)/t20-,21-,26?	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.79E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236355 (US9365576, 108) Show SMILES COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCC(=O)N(C)C1 Show InChI InChI=1S/C26H29ClN6O3/c1-14(2)32-20(19-12-29-26(28)30-24(19)36-4)11-18-23(32)22(15-5-7-16(27)8-6-15)33(25(18)35)17-9-10-21(34)31(3)13-17/h5-8,11-12,14,17,22H,9-10,13H2,1-4H3,(H2,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.02E+3	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236325 (US9365576, 78) Show SMILES COc1nc(N)ncc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)C1CCOCC1 Show InChI InChI=1S/C25H28ClN5O3/c1-14(2)30-20(19-13-28-25(27)29-23(19)33-3)12-18-22(30)21(15-4-6-16(26)7-5-15)31(24(18)32)17-8-10-34-11-9-17/h4-7,12-14,17,21H,8-11H2,1-3H3,(H2,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236248 (US9365576, 1) Show SMILES COc1ccccc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F Show InChI InChI=1S/C29H25Cl2FN2O2/c1-16(2)33-24(20-8-5-6-11-25(20)36-4)15-21-28(33)27(19-13-12-18(30)14-17(19)3)34(29(21)35)23-10-7-9-22(31)26(23)32/h5-16,27H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236250 (US9365576, 3) Show SMILES COc1ccc(F)cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1C)c1cccc(Cl)c1F Show InChI InChI=1S/C29H24Cl2F2N2O2/c1-15(2)34-24(20-13-18(32)9-11-25(20)37-4)14-21-28(34)27(19-10-8-17(30)12-16(19)3)35(29(21)36)23-7-5-6-22(31)26(23)33/h5-15,27H,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.42E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236484 (US9365576, 240) Show SMILES COc1ncc(-c2cc3C(=O)N(C(c3n2C2CC2)c2ccc(Cl)cc2)c2cc(C)c(=O)n(C)c2)c(OC)n1 Show InChI InChI=1S/C28H26ClN5O4/c1-15-11-19(14-32(2)26(15)35)34-23(16-5-7-17(29)8-6-16)24-20(27(34)36)12-22(33(24)18-9-10-18)21-13-30-28(38-4)31-25(21)37-3/h5-8,11-14,18,23H,9-10H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.76E+4	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236485 (US9365576, 241) Show SMILES COc1ncc(cn1)-c1cc2C(=O)N(C(c2n1C1CC1)c1ccc(Cl)cc1)c1cc(C)c(=O)n(C)c1 Show InChI InChI=1S/C27H24ClN5O3/c1-15-10-20(14-31(2)25(15)34)33-23(16-4-6-18(28)7-5-16)24-21(26(33)35)11-22(32(24)19-8-9-19)17-12-29-27(36-3)30-13-17/h4-7,10-14,19,23H,8-9H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair
Cellular tumor antigen p53 [18-26]/Protein Mdm4 [2-185] (Homo sapiens (Human))	BDBM236486 (US9365576, 242) Show SMILES Cc1cc(cn(C)c1=O)N1C(c2c(cc(-c3ccn(C)c(=O)c3)n2C2CC2)C1=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C28H25ClN4O3/c1-16-12-21(15-31(3)27(16)35)33-25(17-4-6-19(29)7-5-17)26-22(28(33)36)14-23(32(26)20-8-9-20)18-10-11-30(2)24(34)13-18/h4-7,10-15,20,25H,8-9H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	25
Novartis AG US Patent					Assay Description Assay 1: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...				US Patent US9365576 (2016) BindingDB Entry DOI: 10.7270/Q2DN43XR
					More data for this Ligand-Target Pair