Compile Data Set for Download or QSAR

Found 647 hits of ic50 for UniProtKB: P30419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50121716 ((3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)be...) Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1ccc(C)cn1 Show InChI InChI=1S/C25H25N3O3/c1-17-9-10-20(28-14-17)24(29)25-18(2)23-21(7-3-8-22(23)31-25)30-13-5-12-27-16-19-6-4-11-26-15-19/h3-4,6-11,14-15,27H,5,12-13,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50220561 (CHEMBL173370) Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1nc2ccccc2n1C Show InChI InChI=1S/C27H26N4O3/c1-18-24-22(33-15-7-14-29-17-19-8-6-13-28-16-19)11-5-12-23(24)34-26(18)25(32)27-30-20-9-3-4-10-21(20)31(27)2/h3-6,8-13,16,29H,7,14-15,17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50220562 (CHEMBL171506) Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1nc2ccccc2n1CC=C Show InChI InChI=1S/C29H28N4O3/c1-3-16-33-23-11-5-4-10-22(23)32-29(33)27(34)28-20(2)26-24(12-6-13-25(26)36-28)35-17-8-15-31-19-21-9-7-14-30-18-21/h3-7,9-14,18,31H,1,8,15-17,19H2,2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50220565 (CHEMBL170524) Show SMILES Cc1nc(sc1C)C(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1C Show InChI InChI=1S/C24H25N3O3S/c1-15-21-19(29-12-6-11-26-14-18-7-5-10-25-13-18)8-4-9-20(21)30-23(15)22(28)24-27-16(2)17(3)31-24/h4-5,7-10,13,26H,6,11-12,14H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50520331 (CHEMBL4445137) Show SMILES CN(C)Cc1nn(C)c2ccc(cc12)-c1ccc(F)c(F)c1OCCc1c(C)nn(C)c1C Show InChI InChI=1S/C25H29F2N5O/c1-15-18(16(2)31(5)28-15)11-12-33-25-19(8-9-21(26)24(25)27)17-7-10-23-20(13-17)22(14-30(3)4)29-32(23)6/h7-10,13H,11-12,14H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Frontier Medicines Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase assessed as reduction in CoASH production by fluorogenic detection based assay				J Med Chem 63: 4430-4444 (2020) Article DOI: 10.1021/acs.jmedchem.9b01581 BindingDB Entry DOI: 10.7270/Q2ZG6WM7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50520331 (CHEMBL4445137) Show SMILES CN(C)Cc1nn(C)c2ccc(cc12)-c1ccc(F)c(F)c1OCCc1c(C)nn(C)c1C Show InChI InChI=1S/C25H29F2N5O/c1-15-18(16(2)31(5)28-15)11-12-33-25-19(8-9-21(26)24(25)27)17-7-10-23-20(13-17)22(14-30(3)4)29-32(23)6/h7-10,13H,11-12,14H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human NMT1 by fluorescence method				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00242 BindingDB Entry DOI: 10.7270/Q2KD22HB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50121720 ((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...) Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1nccn1C Show InChI InChI=1S/C23H24N4O3/c1-16-20-18(29-13-5-10-25-15-17-6-4-9-24-14-17)7-3-8-19(20)30-22(16)21(28)23-26-11-12-27(23)2/h3-4,6-9,11-12,14,25H,5,10,13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50220569 (CHEMBL422896) Show SMILES CC(C)n1c(nc2ccccc12)C(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1C Show InChI InChI=1S/C29H30N4O3/c1-19(2)33-23-11-5-4-10-22(23)32-29(33)27(34)28-20(3)26-24(12-6-13-25(26)36-28)35-16-8-15-31-18-21-9-7-14-30-17-21/h4-7,9-14,17,19,31H,8,15-16,18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM185107 (US9156811, DDD100868) Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1ccc2CCCN(C)Cc2c1 Show InChI InChI=1S/C26H34N4O2S/c1-18(2)15-25-26(19(3)30(5)27-25)28-33(31,32)24-12-10-21(11-13-24)22-9-8-20-7-6-14-29(4)17-23(20)16-22/h8-13,16,18H,6-7,14-15,17H2,1-5H3,(H-,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50220559 (CHEMBL422746) Show SMILES Cc1csc(n1)C(=O)c1oc2cccc(OCCCNCc3cccnc3)c2c1C Show InChI InChI=1S/C23H23N3O3S/c1-15-14-30-23(26-15)21(27)22-16(2)20-18(7-3-8-19(20)29-22)28-11-5-10-25-13-17-6-4-9-24-12-17/h3-4,6-9,12,14,25H,5,10-11,13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184902 (US9156811, DDD86481) Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C24H30Cl2N6O2S/c1-15(2)11-21-23(16(3)31(4)29-21)30-35(33,34)24-19(25)12-18(13-20(24)26)17-5-6-28-22(14-17)32-9-7-27-8-10-32/h5-6,12-15,27H,7-11H2,1-4H3,(H-,30,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184854 (US9156811, DDD86206) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H25ClN6O2S/c1-14-21(15(2)27(3)25-14)26-31(29,30)19-5-4-16(12-18(19)22)17-6-7-24-20(13-17)28-10-8-23-9-11-28/h4-7,12-13,23H,8-11H2,1-3H3,(H-,26,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184848 (US9156811, DDD85646) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24H,6-9H2,1-3H3,(H-,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364113 (CHEMBL1230468) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364113 (CHEMBL1230468) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...				J Med Chem 55: 140-52 (2012) Article DOI: 10.1021/jm201091t BindingDB Entry DOI: 10.7270/Q25Q4WK9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184977 (US9156811, DDD88646) Show SMILES CCN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C23H28Cl2N6O2S/c1-5-31(22-15(2)28-29(4)16(22)3)34(32,33)23-19(24)12-18(13-20(23)25)17-6-7-27-21(14-17)30-10-8-26-9-11-30/h6-7,12-14,26H,5,8-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50220571 (CHEMBL355250) Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1ccccn1 Show InChI InChI=1S/C24H23N3O3/c1-17-22-20(29-14-6-12-26-16-18-7-5-11-25-15-18)9-4-10-21(22)30-24(17)23(28)19-8-2-3-13-27-19/h2-5,7-11,13,15,26H,6,12,14,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50219312 (CHEMBL158172) Show SMILES Cc1c(COc2ccc(F)cc2)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H25FN2O3/c1-18-24(17-30-21-10-8-20(26)9-11-21)31-23-7-2-6-22(25(18)23)29-14-4-13-28-16-19-5-3-12-27-15-19/h2-3,5-12,15,28H,4,13-14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM)				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50219310 (CHEMBL155469) Show SMILES Cc1c(COc2ccc(cc2)C#N)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C26H25N3O3/c1-19-25(18-31-22-10-8-20(15-27)9-11-22)32-24-7-2-6-23(26(19)24)30-14-4-13-29-17-21-5-3-12-28-16-21/h2-3,5-12,16,29H,4,13-14,17-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans N-Myristoyltransferase (Nmt)				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50109882 (3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...) Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM); 3.7-9.4 nM				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50109879 (CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...) Show SMILES Cc1c(COc2cccc(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H24F2N2O3/c1-17-23(16-31-22-10-2-7-19(26)25(22)27)32-21-9-3-8-20(24(17)21)30-13-5-12-29-15-18-6-4-11-28-14-18/h2-4,6-11,14,29H,5,12-13,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50219305 (CHEMBL347895) Show SMILES Cc1c(COc2ccccc2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H25FN2O3/c1-18-24(17-30-21-9-3-2-8-20(21)26)31-23-11-4-10-22(25(18)23)29-14-6-13-28-16-19-7-5-12-27-15-19/h2-5,7-12,15,28H,6,13-14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50219303 (CHEMBL345893) Show SMILES Cc1c(COc2ccc(F)cc2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H24F2N2O3/c1-17-24(16-31-21-9-8-19(26)13-20(21)27)32-23-7-2-6-22(25(17)23)30-12-4-11-29-15-18-5-3-10-28-14-18/h2-3,5-10,13-14,29H,4,11-12,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM)				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50109879 (CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...) Show SMILES Cc1c(COc2cccc(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H24F2N2O3/c1-17-23(16-31-22-10-2-7-19(26)25(22)27)32-21-9-3-8-20(24(17)21)30-13-5-12-29-15-18-6-4-11-28-14-18/h2-4,6-11,14,29H,5,12-13,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM)				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364113 (CHEMBL1230468) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H24Cl2N6O2S/c1-13-20(14(2)28(3)26-13)27-32(30,31)21-17(22)10-16(11-18(21)23)15-4-5-25-19(12-15)29-8-6-24-7-9-29/h4-5,10-12,24,27H,6-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human NMT1 using [3H]-myristoyl-coA/biotinylated CAP5.5 as substrate after 15 mins by scintillation/luminescence counting method				J Med Chem 60: 9790-9806 (2017) Article DOI: 10.1021/acs.jmedchem.7b01255 BindingDB Entry DOI: 10.7270/Q25141NZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM185092 (US9156811, DDD100798) Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1ccc2CCCNCc2c1 Show InChI InChI=1S/C25H32N4O2S/c1-17(2)14-24-25(18(3)29(4)27-24)28-32(30,31)23-11-9-20(10-12-23)21-8-7-19-6-5-13-26-16-22(19)15-21/h7-12,15,17,26H,5-6,13-14,16H2,1-4H3,(H-,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM185101 (US9156811, DDD100807) Show SMILES Cc1nn(C)c(C)c1N(C(F)F)[S+]([O-])(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C22H30Cl2F2N4O2S/c1-14-20(15(2)29(3)28-14)30(22(25)26)33(31,32)21-18(23)12-17(13-19(21)24)7-5-4-6-16-8-10-27-11-9-16/h12-13,16,22,27H,4-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184978 (US9156811, DDD90022) Show SMILES CN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C21H30Cl2N4O2S/c1-14-20(15(2)26(3)25-14)27(4)30(28,29)21-18(22)12-17(13-19(21)23)7-5-6-16-8-10-24-11-9-16/h12-13,16,24H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033480 (CHEMBL3357697) Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C22H32Cl2N4O2S/c1-15-21(16(2)28(4)25-15)26-31(29,30)22-19(23)13-18(14-20(22)24)8-6-5-7-17-9-11-27(3)12-10-17/h13-14,17,26H,5-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033485 (CHEMBL3357702) Show SMILES CN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C22H26Cl2N6O2S/c1-14-21(15(2)28(3)27-14)29(4)33(31,32)22-18(23)11-17(12-19(22)24)16-5-6-26-20(13-16)30-9-7-25-8-10-30/h5-6,11-13,25H,7-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033616 (CHEMBL3358119) Show SMILES Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C22H30Cl2F2N4O2S/c1-14-20(15(2)29(3)28-14)30(22(25)26)33(31,32)21-18(23)12-17(13-19(21)24)7-5-4-6-16-8-10-27-11-9-16/h12-13,16,22,27H,4-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033418 (CHEMBL3357685) Show SMILES CC(C)Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C24H30Cl2N6O2S/c1-15(2)11-21-23(16(3)31(4)29-21)30-35(33,34)24-19(25)12-18(13-20(24)26)17-5-6-28-22(14-17)32-9-7-27-8-10-32/h5-6,12-15,27,30H,7-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033618 (CHEMBL3358121) Show SMILES CN1CCC(CC1)OCCCc1cc(Cl)c(c(Cl)c1)S(=O)(=O)N(C(F)F)c1c(C)nn(C)c1C Show InChI InChI=1S/C22H30Cl2F2N4O3S/c1-14-20(15(2)29(4)27-14)30(22(25)26)34(31,32)21-18(23)12-16(13-19(21)24)6-5-11-33-17-7-9-28(3)10-8-17/h12-13,17,22H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM185083 (US9156811, DDD100169) Show SMILES CN1CCC(CC1)OCCCc1cc(Cl)c(c(Cl)c1)[S+]([O-])(=O)N(C(F)F)c1c(C)nn(C)c1C Show InChI InChI=1S/C22H30Cl2F2N4O3S/c1-14-20(15(2)29(4)27-14)30(22(25)26)34(31,32)21-18(23)12-16(13-19(21)24)6-5-11-33-17-7-9-28(3)10-8-17/h12-13,17,22H,5-11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184988 (US9156811, DDD90107) Show SMILES CN1CCC(Cc2cccc(c2)-c2ccc(cc2)[S+]([O-])(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C25H32N4O2S/c1-18-25(19(2)29(4)26-18)27-32(30,31)24-10-8-22(9-11-24)23-7-5-6-21(17-23)16-20-12-14-28(3)15-13-20/h5-11,17,20H,12-16H2,1-4H3,(H-,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184943 (US9156811, DDD88193) Show SMILES CN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C22H26Cl2N6O2S/c1-14-21(15(2)28(3)27-14)29(4)33(31,32)22-18(23)11-17(12-19(22)24)16-5-6-26-20(13-16)30-9-7-25-8-10-30/h5-6,11-13,25H,7-10H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033617 (CHEMBL3358120) Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C23H32Cl2F2N4O2S/c1-15-21(16(2)30(4)28-15)31(23(26)27)34(32,33)22-19(24)13-18(14-20(22)25)8-6-5-7-17-9-11-29(3)12-10-17/h13-14,17,23H,5-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human NMT1 using [3H]-myristoyl-coA/biotinylated CAP5.5 as substrate after 15 mins by scintillation/luminescence counting method				J Med Chem 60: 9790-9806 (2017) Article DOI: 10.1021/acs.jmedchem.7b01255 BindingDB Entry DOI: 10.7270/Q25141NZ
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184992 (US9156811, DDD90118) Show SMILES CN(c1c(C)nn(C)c1C)[S+]([O-])(=O)c1c(Cl)cc(cc1Cl)-c1cccc(CN2CCN(C)CC2)c1 Show InChI InChI=1S/C25H31Cl2N5O2S/c1-17-24(18(2)30(4)28-17)31(5)35(33,34)25-22(26)14-21(15-23(25)27)20-8-6-7-19(13-20)16-32-11-9-29(3)10-12-32/h6-8,13-15H,9-12,16H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033482 (CHEMBL3357699) Show SMILES Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cc(CCCCC2CCNCC2)cc1Cl Show InChI InChI=1S/C21H30Cl2N4O2S/c1-14-20(15(2)27(3)25-14)26-30(28,29)21-18(22)12-17(13-19(21)23)7-5-4-6-16-8-10-24-11-9-16/h12-13,16,24,26H,4-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50033617 (CHEMBL3358120) Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)S(=O)(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C23H32Cl2F2N4O2S/c1-15-21(16(2)30(4)28-15)31(23(26)27)34(32,33)22-19(24)13-18(14-20(22)25)8-6-5-7-17-9-11-29(3)12-10-17/h13-14,17,23H,5-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 assessed as transfer of [3H]-myristic acid to a biotinylated substrate peptide (GCGGSKVKPQPPQAK(biotin)-...				J Med Chem 57: 9855-69 (2014) Article DOI: 10.1021/jm500809c BindingDB Entry DOI: 10.7270/Q2ZC84G2
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50219312 (CHEMBL158172) Show SMILES Cc1c(COc2ccc(F)cc2)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H25FN2O3/c1-18-24(17-30-21-10-8-20(26)9-11-21)31-23-7-2-6-22(25(18)23)29-14-4-13-28-16-19-5-3-12-27-15-19/h2-3,5-12,15,28H,4,13-14,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50109882 (3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...) Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans Nmt (CaNmt)				Bioorg Med Chem Lett 13: 87-91 (2003) BindingDB Entry DOI: 10.7270/Q25D8V2K
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1/2 (Homo sapiens (Human))	BDBM50109882 (3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...) Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Roche Research Center Curated by ChEMBL					Assay Description Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...				Bioorg Med Chem Lett 12: 607-10 (2002) BindingDB Entry DOI: 10.7270/Q2PC34K1
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM185061 (US9156811, DDD100144) Show SMILES CN1CCC(CCCCc2cc(Cl)c(c(Cl)c2)[S+]([O-])(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C23H32Cl2F2N4O2S/c1-15-21(16(2)30(4)28-15)31(23(26)27)34(32,33)22-19(24)13-18(14-20(22)25)8-6-5-7-17-9-11-29(3)12-10-17/h13-14,17,23H,5-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184937 (US9156811, DDD88186) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1C)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C22H28N6O2S/c1-15-13-18(19-7-8-24-21(14-19)28-11-9-23-10-12-28)5-6-20(15)31(29,30)26-22-16(2)25-27(4)17(22)3/h5-8,13-14,23H,9-12H2,1-4H3,(H-,26,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM185108 (US9156811, DDD100869) Show SMILES CC(C)Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1cccc(CNCCc2cccnc2)c1 Show InChI InChI=1S/C29H35N5O2S/c1-21(2)17-28-29(22(3)34(4)32-28)33-37(35,36)27-12-10-25(11-13-27)26-9-5-7-24(18-26)20-31-16-14-23-8-6-15-30-19-23/h5-13,15,18-19,21,31H,14,16-17,20H2,1-4H3,(H-,33,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM50364135 (CHEMBL1951295) Show SMILES CN1CCN(Cc2cccc(c2)-c2cc(Cl)c(c(Cl)c2)S(=O)(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C24H29Cl2N5O2S/c1-16-23(17(2)30(4)27-16)28-34(32,33)24-21(25)13-20(14-22(24)26)19-7-5-6-18(12-19)15-31-10-8-29(3)9-11-31/h5-7,12-14,28H,8-11,15H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human N-myristoyltransferase 1 using [3H]myristoyl-CoA and GCGGSKVKPQPPQAK(biotin)-amide as substrate preincubated for 5 mins prior sub...				J Med Chem 55: 140-52 (2012) Article DOI: 10.1021/jm201091t BindingDB Entry DOI: 10.7270/Q25Q4WK9
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM185078 (US9156811, DDD100164) Show SMILES CN1CCCN(CCCc2cc(Cl)c(c(Cl)c2)[S+]([O-])(=O)N(C(F)F)c2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C22H31Cl2F2N5O2S/c1-15-20(16(2)29(4)27-15)31(22(25)26)34(32,33)21-18(23)13-17(14-19(21)24)7-5-9-30-10-6-8-28(3)11-12-30/h13-14,22H,5-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184965 (US9156811, DDD88558) Show SMILES CN1CCN(Cc2cccc(c2)-c2cc(Cl)c(c(Cl)c2)[S+]([O-])(=O)Nc2c(C)nn(C)c2C)CC1 Show InChI InChI=1S/C24H29Cl2N5O2S/c1-16-23(17(2)30(4)27-16)28-34(32,33)24-21(25)13-20(14-22(24)26)19-7-5-6-18(12-19)15-31-10-8-29(3)9-11-31/h5-7,12-14H,8-11,15H2,1-4H3,(H-,28,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair
Glycylpeptide N-tetradecanoyltransferase 1 (Homo sapiens (Human))	BDBM184860 (US9156811, DDD86213) Show SMILES Cc1nn(C)c(C)c1N[S+]([O-])(=O)c1ccc(cc1)-c1ccnc(c1)N1CCNCC1 Show InChI InChI=1S/C21H26N6O2S/c1-15-21(16(2)26(3)24-15)25-30(28,29)19-6-4-17(5-7-19)18-8-9-23-20(14-18)27-12-10-22-11-13-27/h4-9,14,22H,10-13H2,1-3H3,(H-,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	25
Univeristy of Dundee US Patent					Assay Description Measurement of the ability of compounds to inhibit the NMT-1 and/or NMT-2 enzyme isoforms of human, trypanosome (T. brucei), leishmanial (L. major) a...				US Patent US9156811 (2015) BindingDB Entry DOI: 10.7270/Q2K35SGM
					More data for this Ligand-Target Pair

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