Compile Data Set for Download or QSAR

Found 157 hits Enz. Inhib. hit(s) with all data for entry = 50019452   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50204794 (8-(8-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Fc1cccc2CCCC(N3CCC4(CC3)N(CNC4=O)c3ccccc3)c12 |w:9.9| Show InChI InChI=1S/C23H26FN3O/c24-19-10-4-6-17-7-5-11-20(21(17)19)26-14-12-23(13-15-26)22(28)25-16-27(23)18-8-2-1-3-9-18/h1-4,6,8-10,20H,5,7,11-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204769 (8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Fc1cccc2C(CCCc12)N1CCC2(CC1)N(CNC2=O)c1ccccc1 |w:6.12| Show InChI InChI=1S/C23H26FN3O/c24-20-10-4-9-19-18(20)8-5-11-21(19)26-14-12-23(13-15-26)22(28)25-16-27(23)17-6-2-1-3-7-17/h1-4,6-7,9-10,21H,5,8,11-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204768 (8-(7-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Fc1ccc2CCCC(N3CCC4(CC3)N(CNC4=O)c3ccccc3)c2c1 |w:8.8| Show InChI InChI=1S/C23H26FN3O/c24-18-10-9-17-5-4-8-21(20(17)15-18)26-13-11-23(12-14-26)22(28)25-16-27(23)19-6-2-1-3-7-19/h1-3,6-7,9-10,15,21H,4-5,8,11-14,16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204783 (1-phenyl-8-(1-phenyl-pentyl)-1,3,8-triaza-spiro[4....) Show SMILES CCCCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H31N3O/c1-2-3-14-22(20-10-6-4-7-11-20)26-17-15-24(16-18-26)23(28)25-19-27(24)21-12-8-5-9-13-21/h4-13,22H,2-3,14-19H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50087008 (8-indan-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCc2ccccc12 Show InChI InChI=1S/C22H25N3O/c26-21-22(25(16-23-21)18-7-2-1-3-8-18)12-14-24(15-13-22)20-11-10-17-6-4-5-9-19(17)20/h1-9,20H,10-16H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM26947 (8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES CC1(C)CCC(N2CCC3(CC2)N(CNC3=O)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H31N3O/c1-24(2)13-12-22(20-10-6-7-11-21(20)24)27-16-14-25(15-17-27)23(29)26-18-28(25)19-8-4-3-5-9-19/h3-11,22H,12-18H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204764 (8-(6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-naphth...) Show SMILES CC1(C)CCC(N2CCC3(CC2)N(CNC3=O)c2ccccc2)c2ccc(Cl)cc12 |w:5.5| Show InChI InChI=1S/C25H30ClN3O/c1-24(2)11-10-22(20-9-8-18(26)16-21(20)24)28-14-12-25(13-15-28)23(30)27-17-29(25)19-6-4-3-5-7-19/h3-9,16,22H,10-15,17H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50087015 (1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCc2ccccc12 Show InChI InChI=1S/C23H27N3O/c27-22-23(26(17-24-22)19-9-2-1-3-10-19)13-15-25(16-14-23)21-12-6-8-18-7-4-5-11-20(18)21/h1-5,7,9-11,21H,6,8,12-17H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204785 (8-(4-methyl-1-phenyl-pentyl)-1-phenyl-1,3,8-triaza...) Show SMILES CC(C)CCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H33N3O/c1-20(2)13-14-23(21-9-5-3-6-10-21)27-17-15-25(16-18-27)24(29)26-19-28(25)22-11-7-4-8-12-22/h3-12,20,23H,13-19H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204778 (8-(5-chloro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Clc1cccc2C(CCCc12)N1CCC2(CC1)N(CNC2=O)c1ccccc1 |w:6.12| Show InChI InChI=1S/C23H26ClN3O/c24-20-10-4-9-19-18(20)8-5-11-21(19)26-14-12-23(13-15-26)22(28)25-16-27(23)17-6-2-1-3-7-17/h1-4,6-7,9-10,21H,5,8,11-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM26919 (8-[(2,6-dichlorophenyl)methyl]-1-phenyl-1,3,8-tria...) Show SMILES Clc1cccc(Cl)c1CN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H21Cl2N3O/c21-17-7-4-8-18(22)16(17)13-24-11-9-20(10-12-24)19(26)23-14-25(20)15-5-2-1-3-6-15/h1-8H,9-14H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204784 (1-phenyl-8-(1-phenyl-butyl)-1,3,8-triaza-spiro[4.5...) Show SMILES CCCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c1-2-9-21(19-10-5-3-6-11-19)25-16-14-23(15-17-25)22(27)24-18-26(23)20-12-7-4-8-13-20/h3-8,10-13,21H,2,9,14-18H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204779 (8-(8-chloro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Clc1cccc2CCCC(N3CCC4(CC3)N(CNC4=O)c3ccccc3)c12 |w:9.9| Show InChI InChI=1S/C23H26ClN3O/c24-19-10-4-6-17-7-5-11-20(21(17)19)26-14-12-23(13-15-26)22(28)25-16-27(23)18-8-2-1-3-9-18/h1-4,6,8-10,20H,5,7,11-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204767 (8-(2-chloro-benzyl)-1-phenyl-1,3,8-triaza-spiro[4....) Show SMILES Clc1ccccc1CN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H22ClN3O/c21-18-9-5-4-6-16(18)14-23-12-10-20(11-13-23)19(25)22-15-24(20)17-7-2-1-3-8-17/h1-9H,10-15H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204765 (1-phenyl-8-(1-phenyl-ethyl)-1,3,8-triaza-spiro[4.5...) Show SMILES CC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H25N3O/c1-17(18-8-4-2-5-9-18)23-14-12-21(13-15-23)20(25)22-16-24(21)19-10-6-3-7-11-19/h2-11,17H,12-16H2,1H3,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204775 (8-(cyclopentyl-phenyl-methyl)-1-phenyl-1,3,8-triaz...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C(C1CCCC1)c1ccccc1 |w:17.19| Show InChI InChI=1S/C25H31N3O/c29-24-25(28(19-26-24)22-13-5-2-6-14-22)15-17-27(18-16-25)23(21-11-7-8-12-21)20-9-3-1-4-10-20/h1-6,9-10,13-14,21,23H,7-8,11-12,15-19H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50204794 (8-(8-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Fc1cccc2CCCC(N3CCC4(CC3)N(CNC4=O)c3ccccc3)c12 |w:9.9| Show InChI InChI=1S/C23H26FN3O/c24-19-10-4-6-17-7-5-11-20(21(17)19)26-14-12-23(13-15-26)22(28)25-16-27(23)18-8-2-1-3-9-18/h1-4,6,8-10,20H,5,7,11-16H2,(H,25,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204773 (8-[bis-(2-fluoro-phenyl)-methyl]-1-phenyl-1,3,8-tr...) Show SMILES Fc1ccccc1C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1F Show InChI InChI=1S/C26H25F2N3O/c27-22-12-6-4-10-20(22)24(21-11-5-7-13-23(21)28)30-16-14-26(15-17-30)25(32)29-18-31(26)19-8-2-1-3-9-19/h1-13,24H,14-18H2,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM26949 (8-[bis(2-chlorophenyl)methyl]-1-phenyl-1,3,8-triaz...) Show SMILES Clc1ccccc1C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1Cl Show InChI InChI=1S/C26H25Cl2N3O/c27-22-12-6-4-10-20(22)24(21-11-5-7-13-23(21)28)30-16-14-26(15-17-30)25(32)29-18-31(26)19-8-2-1-3-9-19/h1-13,24H,14-18H2,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204776 (8-(6-fluoro-4,4-dimethyl-1,2,3,4-tetrahydro-naphth...) Show SMILES CC1(C)CCC(N2CCC3(CC2)N(CNC3=O)c2ccccc2)c2ccc(F)cc12 |w:5.5| Show InChI InChI=1S/C25H30FN3O/c1-24(2)11-10-22(20-9-8-18(26)16-21(20)24)28-14-12-25(13-15-28)23(30)27-17-29(25)19-6-4-3-5-7-19/h3-9,16,22H,10-15,17H2,1-2H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204782 (8-[(2-chloro-phenyl)-phenyl-methyl]-1-phenyl-1,3,8...) Show SMILES Clc1ccccc1C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 |w:7.8| Show InChI InChI=1S/C26H26ClN3O/c27-23-14-8-7-13-22(23)24(20-9-3-1-4-10-20)29-17-15-26(16-18-29)25(31)28-19-30(26)21-11-5-2-6-12-21/h1-14,24H,15-19H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204791 (8-di-o-tolylmethyl-1-phenyl-1,3,8-triaza-spiro[4.5...) Show SMILES Cc1ccccc1C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1C Show InChI InChI=1S/C28H31N3O/c1-21-10-6-8-14-24(21)26(25-15-9-7-11-22(25)2)30-18-16-28(17-19-30)27(32)29-20-31(28)23-12-4-3-5-13-23/h3-15,26H,16-20H2,1-2H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204790 (8-(7-chloro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Clc1ccc2CCCC(N3CCC4(CC3)N(CNC4=O)c3ccccc3)c2c1 |w:8.8| Show InChI InChI=1S/C23H26ClN3O/c24-18-10-9-17-5-4-8-21(20(17)15-18)26-13-11-23(12-14-26)22(28)25-16-27(23)19-6-2-1-3-7-19/h1-3,6-7,9-10,15,21H,4-5,8,11-14,16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50175929 (8-benzyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-o...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H23N3O/c24-19-20(23(16-21-19)18-9-5-2-6-10-18)11-13-22(14-12-20)15-17-7-3-1-4-8-17/h1-10H,11-16H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204781 (8-[(2-fluoro-phenyl)-phenyl-methyl]-1-phenyl-1,3,8...) Show SMILES Fc1ccccc1C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 |w:7.8| Show InChI InChI=1S/C26H26FN3O/c27-23-14-8-7-13-22(23)24(20-9-3-1-4-10-20)29-17-15-26(16-18-29)25(31)28-19-30(26)21-11-5-2-6-12-21/h1-14,24H,15-19H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50204779 (8-(8-chloro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Clc1cccc2CCCC(N3CCC4(CC3)N(CNC4=O)c3ccccc3)c12 |w:9.9| Show InChI InChI=1S/C23H26ClN3O/c24-19-10-4-6-17-7-5-11-20(21(17)19)26-14-12-23(13-15-26)22(28)25-16-27(23)18-8-2-1-3-9-18/h1-4,6,8-10,20H,5,7,11-16H2,(H,25,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204771 (1-phenyl-8-(phenyl-o-tolyl-methyl)-1,3,8-triaza-sp...) Show SMILES Cc1ccccc1C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 |w:7.8| Show InChI InChI=1S/C27H29N3O/c1-21-10-8-9-15-24(21)25(22-11-4-2-5-12-22)29-18-16-27(17-19-29)26(31)28-20-30(27)23-13-6-3-7-14-23/h2-15,25H,16-20H2,1H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204783 (1-phenyl-8-(1-phenyl-pentyl)-1,3,8-triaza-spiro[4....) Show SMILES CCCCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H31N3O/c1-2-3-14-22(20-10-6-4-7-11-20)26-17-15-24(16-18-26)23(28)25-19-27(24)21-12-8-5-9-13-21/h4-13,22H,2-3,14-19H2,1H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204786 (1-phenyl-8-thiophen-3-ylmethyl-1,3,8-triaza-spiro[...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(Cc2ccsc2)CC1 Show InChI InChI=1S/C18H21N3OS/c22-17-18(21(14-19-17)16-4-2-1-3-5-16)7-9-20(10-8-18)12-15-6-11-23-13-15/h1-6,11,13H,7-10,12,14H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204769 (8-(5-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Fc1cccc2C(CCCc12)N1CCC2(CC1)N(CNC2=O)c1ccccc1 |w:6.12| Show InChI InChI=1S/C23H26FN3O/c24-20-10-4-9-19-18(20)8-5-11-21(19)26-14-12-23(13-15-26)22(28)25-16-27(23)17-6-2-1-3-7-17/h1-4,6-7,9-10,21H,5,8,11-16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204772 (8-(6,7-dichloro-4,4-dimethyl-1,2,3,4-tetrahydro-na...) Show SMILES CC1(C)CCC(N2CCC3(CC2)N(CNC3=O)c2ccccc2)c2cc(Cl)c(Cl)cc12 |w:5.5| Show InChI InChI=1S/C25H29Cl2N3O/c1-24(2)9-8-22(18-14-20(26)21(27)15-19(18)24)29-12-10-25(11-13-29)23(31)28-16-30(25)17-6-4-3-5-7-17/h3-7,14-15,22H,8-13,16H2,1-2H3,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204762 (1-phenyl-8-(6,7,8,9-tetrahydro-5H-benzocyclohepten...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCCCc2ccccc12 |w:17.19| Show InChI InChI=1S/C24H29N3O/c28-23-24(27(18-25-23)20-10-2-1-3-11-20)14-16-26(17-15-24)22-13-7-5-9-19-8-4-6-12-21(19)22/h1-4,6,8,10-12,22H,5,7,9,13-18H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204767 (8-(2-chloro-benzyl)-1-phenyl-1,3,8-triaza-spiro[4....) Show SMILES Clc1ccccc1CN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H22ClN3O/c21-18-9-5-4-6-16(18)14-23-12-10-20(11-13-23)19(25)22-15-24(20)17-7-2-1-3-8-17/h1-9H,10-15H2,(H,22,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204787 (1-phenyl-8-(1-phenyl-propyl)-1,3,8-triaza-spiro[4....) Show SMILES CCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H27N3O/c1-2-20(18-9-5-3-6-10-18)24-15-13-22(14-16-24)21(26)23-17-25(22)19-11-7-4-8-12-19/h3-12,20H,2,13-17H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50087008 (8-indan-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCc2ccccc12 Show InChI InChI=1S/C22H25N3O/c26-21-22(25(16-23-21)18-7-2-1-3-8-18)12-14-24(15-13-22)20-11-10-17-6-4-5-9-19(17)20/h1-9,20H,10-16H2,(H,23,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50204783 (1-phenyl-8-(1-phenyl-pentyl)-1,3,8-triaza-spiro[4....) Show SMILES CCCCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H31N3O/c1-2-3-14-22(20-10-6-4-7-11-20)26-17-15-24(16-18-26)23(28)25-19-27(24)21-12-8-5-9-13-21/h4-13,22H,2-3,14-19H2,1H3,(H,25,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM26888 (8-(diphenylmethyl)-1-phenyl-1,3,8-triazaspiro[4.5]...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H27N3O/c30-25-26(29(20-27-25)23-14-8-3-9-15-23)16-18-28(19-17-26)24(21-10-4-1-5-11-21)22-12-6-2-7-13-22/h1-15,24H,16-20H2,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204784 (1-phenyl-8-(1-phenyl-butyl)-1,3,8-triaza-spiro[4.5...) Show SMILES CCCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H29N3O/c1-2-9-21(19-10-5-3-6-11-19)25-16-14-23(15-17-25)22(27)24-18-26(23)20-12-7-4-8-13-20/h3-8,10-13,21H,2,9,14-18H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204786 (1-phenyl-8-thiophen-3-ylmethyl-1,3,8-triaza-spiro[...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(Cc2ccsc2)CC1 Show InChI InChI=1S/C18H21N3OS/c22-17-18(21(14-19-17)16-4-2-1-3-5-16)7-9-20(10-8-18)12-15-6-11-23-13-15/h1-6,11,13H,7-10,12,14H2,(H,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204775 (8-(cyclopentyl-phenyl-methyl)-1-phenyl-1,3,8-triaz...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C(C1CCCC1)c1ccccc1 |w:17.19| Show InChI InChI=1S/C25H31N3O/c29-24-25(28(19-26-24)22-13-5-2-6-14-22)15-17-27(18-16-25)23(21-11-7-8-12-21)20-9-3-1-4-10-20/h1-6,9-10,13-14,21,23H,7-8,11-12,15-19H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204785 (8-(4-methyl-1-phenyl-pentyl)-1-phenyl-1,3,8-triaza...) Show SMILES CC(C)CCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H33N3O/c1-20(2)13-14-23(21-9-5-3-6-10-21)27-17-15-25(16-18-27)24(29)26-19-28(25)22-11-7-4-8-12-22/h3-12,20,23H,13-19H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50204785 (8-(4-methyl-1-phenyl-pentyl)-1-phenyl-1,3,8-triaza...) Show SMILES CC(C)CCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H33N3O/c1-20(2)13-14-23(21-9-5-3-6-10-21)27-17-15-25(16-18-27)24(29)26-19-28(25)22-11-7-4-8-12-22/h3-12,20,23H,13-19H2,1-2H3,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM26919 (8-[(2,6-dichlorophenyl)methyl]-1-phenyl-1,3,8-tria...) Show SMILES Clc1cccc(Cl)c1CN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H21Cl2N3O/c21-17-7-4-8-18(22)16(17)13-24-11-9-20(10-12-24)19(26)23-14-25(20)15-5-2-1-3-6-15/h1-8H,9-14H2,(H,23,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50087008 (8-indan-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1CCc2ccccc12 Show InChI InChI=1S/C22H25N3O/c26-21-22(25(16-23-21)18-7-2-1-3-8-18)12-14-24(15-13-22)20-11-10-17-6-4-5-9-19(17)20/h1-9,20H,10-16H2,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50204768 (8-(7-fluoro-1,2,3,4-tetrahydro-naphthalen-1-yl)-1-...) Show SMILES Fc1ccc2CCCC(N3CCC4(CC3)N(CNC4=O)c3ccccc3)c2c1 |w:8.8| Show InChI InChI=1S/C23H26FN3O/c24-18-10-9-17-5-4-8-21(20(17)15-18)26-13-11-23(12-14-26)22(28)25-16-27(23)19-6-2-1-3-7-19/h1-3,6-7,9-10,15,21H,4-5,8,11-14,16H2,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50204767 (8-(2-chloro-benzyl)-1-phenyl-1,3,8-triaza-spiro[4....) Show SMILES Clc1ccccc1CN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C20H22ClN3O/c21-18-9-5-4-6-16(18)14-23-12-10-20(11-13-23)19(25)22-15-24(20)17-7-2-1-3-8-17/h1-9H,10-15H2,(H,22,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204793 (8-(5H-dibenzo[a,d]cyclohepten-5-yl)-1-phenyl-1,3,8...) Show SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)C1c2ccccc2C=Cc2ccccc12 |c:28| Show InChI InChI=1S/C28H27N3O/c32-27-28(31(20-29-27)23-10-2-1-3-11-23)16-18-30(19-17-28)26-24-12-6-4-8-21(24)14-15-22-9-5-7-13-25(22)26/h1-15,26H,16-20H2,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM26947 (8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES CC1(C)CCC(N2CCC3(CC2)N(CNC3=O)c2ccccc2)c2ccccc12 Show InChI InChI=1S/C25H31N3O/c1-24(2)13-12-22(20-10-6-7-11-21(20)24)27-16-14-25(15-17-27)23(29)26-18-28(25)19-8-4-3-5-9-19/h3-11,22H,12-18H2,1-2H3,(H,26,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50204764 (8-(6-chloro-4,4-dimethyl-1,2,3,4-tetrahydro-naphth...) Show SMILES CC1(C)CCC(N2CCC3(CC2)N(CNC3=O)c2ccccc2)c2ccc(Cl)cc12 |w:5.5| Show InChI InChI=1S/C25H30ClN3O/c1-24(2)11-10-22(20-9-8-18(26)16-21(20)24)28-14-12-25(13-15-28)23(30)27-17-29(25)19-6-4-3-5-7-19/h3-9,16,22H,10-15,17H2,1-2H3,(H,27,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50204770 (8-[bis-(4-fluoro-phenyl)-methyl]-1-phenyl-1,3,8-tr...) Show SMILES Fc1ccc(cc1)C(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C26H25F2N3O/c27-21-10-6-19(7-11-21)24(20-8-12-22(28)13-9-20)30-16-14-26(15-17-30)25(32)29-18-31(26)23-4-2-1-3-5-23/h1-13,24H,14-18H2,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]nociceptin from human nociceptin receptor expressed in CHO cell membrane				Bioorg Med Chem Lett 17: 2281-4 (2007) Article DOI: 10.1016/j.bmcl.2007.01.069 BindingDB Entry DOI: 10.7270/Q2T43SRZ
					More data for this Ligand-Target Pair

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