Compile Data Set for Download or QSAR

Found 96 hits Enz. Inhib. hit(s) with all data for entry = 484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272075 ((S)-1-(2,6-Difluorophenyl)-5-(3-fluoro-2- methylph...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1c(F)cccc1F)C(=O)NO |r,wU:8.27,(-1.7,-2.72,;-.37,-3.49,;-.37,-5.03,;-1.7,-5.8,;.96,-5.8,;2.3,-5.03,;2.3,-3.49,;.96,-2.72,;.96,-1.18,;-.28,-2.09,;-1.53,-1.18,;-3.07,-1.18,;-3.54,.28,;-2.3,1.18,;-1.05,.28,;.49,.28,;-2.3,2.72,;-3.63,3.49,;-4.97,2.72,;-3.63,5.03,;-2.3,5.8,;-.96,5.03,;-.96,3.49,;.37,2.72,;2.3,-.41,;2.3,1.13,;3.63,-1.18,;4.97,-.41,)| Show InChI InChI=1S/C20H16F3N3O2/c1-11-13(4-2-5-14(11)21)20(19(27)25-28)8-12-10-24-26(17(12)9-20)18-15(22)6-3-7-16(18)23/h2-7,10,28H,8-9H2,1H3,(H,25,27)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272078 ((S)-1-(2-Chloro-6-fluorophenyl)-5-(3-fluoro-2- met...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1c(F)cccc1Cl)C(=O)NO |r,wD:8.8,(-.17,-3.49,;1.37,-3.49,;2.14,-4.83,;1.37,-6.16,;3.68,-4.83,;4.45,-3.49,;3.68,-2.16,;2.14,-2.16,;1.37,-.83,;.12,-1.73,;-1.13,-.83,;-2.67,-.83,;-3.14,.64,;-1.9,1.54,;-.65,.64,;.89,.64,;-1.9,3.08,;-.56,3.85,;.77,3.08,;-.56,5.39,;-1.9,6.16,;-3.23,5.39,;-3.23,3.85,;-4.56,3.08,;2.77,-.2,;4.02,-1.11,;2.93,1.33,;4.56,2.27,)| Show InChI InChI=1S/C20H16ClF2N3O2/c1-11-13(4-2-6-15(11)22)20(19(27)25-28)8-12-10-24-26(17(12)9-20)18-14(21)5-3-7-16(18)23/h2-7,10,28H,8-9H2,1H3,(H,25,27)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272071 ((S)-1-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccccc1Cl)C(=O)NO |r| Show InChI InChI=1S/C20H17ClFN3O2/c1-12-14(5-4-7-16(12)22)20(19(26)24-27)9-13-11-23-25(18(13)10-20)17-8-3-2-6-15(17)21/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272074 ((S)-1-(3-Chloro-2-fluorophenyl)-5-(3-fluoro-2- met...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1cccc(Cl)c1F)C(=O)NO |r| Show InChI InChI=1S/C20H16ClF2N3O2/c1-11-13(4-2-6-15(11)22)20(19(27)25-28)8-12-10-24-26(17(12)9-20)16-7-3-5-14(21)18(16)23/h2-7,10,28H,8-9H2,1H3,(H,25,27)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272067 ((S)-5-(3-Fluoro-2-methylphenyl)-l-(2-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccccc1F)C(=O)NO |r| Show InChI InChI=1S/C20H17F2N3O2/c1-12-14(5-4-7-15(12)21)20(19(26)24-27)9-13-11-23-25(18(13)10-20)17-8-3-2-6-16(17)22/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272079 ((S)-5-(3-Fluoro-2-methylphenyl)-1-(2-fluoro-6- met...) Show SMILES Cc1cccc(F)c1-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r,wD:13.22,(-4.97,2.72,;-3.63,3.49,;-3.63,5.03,;-2.3,5.8,;-.96,5.03,;-.96,3.49,;.37,2.72,;-2.3,2.72,;-2.3,1.18,;-3.54,.28,;-3.07,-1.18,;-1.53,-1.18,;-.28,-2.09,;.96,-1.18,;.49,.28,;-1.05,.28,;2.3,-.41,;2.3,1.13,;3.63,-1.18,;4.97,-.41,;.96,-2.72,;2.3,-3.49,;2.3,-5.03,;.96,-5.8,;-.37,-5.03,;-1.7,-5.8,;-.37,-3.49,;-1.7,-2.72,)| Show InChI InChI=1S/C21H19F2N3O2/c1-12-5-3-8-17(23)19(12)26-18-10-21(20(27)25-28,9-14(18)11-24-26)15-6-4-7-16(22)13(15)2/h3-8,11,28H,9-10H2,1-2H3,(H,25,27)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272076 ((S)-1-(2,5-Dimethylphenyl)-5-(3-fluoro-2- methylph...) Show SMILES Cc1ccc(C)c(c1)-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C22H22FN3O2/c1-13-7-8-14(2)19(9-13)26-20-11-22(21(27)25-28,10-16(20)12-24-26)17-5-4-6-18(23)15(17)3/h4-9,12,28H,10-11H2,1-3H3,(H,25,27)/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272066 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-l-(o- to...) Show SMILES Cc1ccccc1-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H20FN3O2/c1-13-6-3-4-9-18(13)25-19-11-21(20(26)24-27,10-15(19)12-23-25)16-7-5-8-17(22)14(16)2/h3-9,12,27H,10-11H2,1-2H3,(H,24,26)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272158 ((R)-1-Benzyl-4-(3-fluoro-2-methylphenyl)-N-hydroxy...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2c1cnn2Cc1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C21H20FN3O2/c1-14-16(8-5-9-18(14)22)21(20(26)24-27)11-10-19-17(21)12-23-25(19)13-15-6-3-2-4-7-15/h2-9,12,27H,10-11,13H2,1H3,(H,24,26)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272077 ((S)-1-(2,6-Dimethylphenyl)-5-(3-fluoro-2- methylph...) Show SMILES Cc1cccc(C)c1-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r,wD:13.22,(-4.97,2.72,;-3.63,3.49,;-3.63,5.03,;-2.3,5.8,;-.96,5.03,;-.96,3.49,;.37,2.72,;-2.3,2.72,;-2.3,1.18,;-3.54,.28,;-3.07,-1.18,;-1.53,-1.18,;-.28,-2.09,;.96,-1.18,;.49,.28,;-1.05,.28,;2.3,-.41,;2.3,1.13,;3.63,-1.18,;4.97,-.41,;.96,-2.72,;2.3,-3.49,;2.3,-5.03,;.96,-5.8,;-.37,-5.03,;-1.7,-5.8,;-.37,-3.49,;-1.7,-2.72,)| Show InChI InChI=1S/C22H22FN3O2/c1-13-6-4-7-14(2)20(13)26-19-11-22(21(27)25-28,10-16(19)12-24-26)17-8-5-9-18(23)15(17)3/h4-9,12,28H,10-11H2,1-3H3,(H,25,27)/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272088 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(m- to...) Show SMILES Cc1cccc(c1)-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H20FN3O2/c1-13-5-3-6-16(9-13)25-19-11-21(20(26)24-27,10-15(19)12-23-25)17-7-4-8-18(22)14(17)2/h3-9,12,27H,10-11H2,1-2H3,(H,24,26)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272065 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C20H18FN3O2/c1-13-16(8-5-9-17(13)21)20(19(25)23-26)10-14-12-22-24(18(14)11-20)15-6-3-2-4-7-15/h2-9,12,26H,10-11H2,1H3,(H,23,25)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272081 ((S)-1-(2,4-Difluorophenyl)-5-(3-fluoro-2- methylph...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(F)cc1F)C(=O)NO |r| Show InChI InChI=1S/C20H16F3N3O2/c1-11-14(3-2-4-15(11)22)20(19(27)25-28)8-12-10-24-26(18(12)9-20)17-6-5-13(21)7-16(17)23/h2-7,10,28H,8-9H2,1H3,(H,25,27)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272080 ((S)-5-(3-Fluoro-2-methylphenyl)-1-(5-fluoropyridin...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(F)cn1)C(=O)NO |r| Show InChI InChI=1S/C19H16F2N4O2/c1-11-14(3-2-4-15(11)21)19(18(26)24-27)7-12-9-23-25(16(12)8-19)17-6-5-13(20)10-22-17/h2-6,9-10,27H,7-8H2,1H3,(H,24,26)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272155 ((S)-1-(2-Chloro-4-fluorophenyl)-5-(3-fluoro-2- met...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(F)cc1Cl)C(=O)NO |r| Show InChI InChI=1S/C20H16ClF2N3O2/c1-11-14(3-2-4-16(11)23)20(19(27)25-28)8-12-10-24-26(18(12)9-20)17-6-5-13(22)7-15(17)21/h2-7,10,28H,8-9H2,1H3,(H,25,27)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272082 ((S)-1-Cyclopentyl-5-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(C3CCCC3)c2C1)C(=O)NO |r| Show InChI InChI=1S/C19H22FN3O2/c1-12-15(7-4-8-16(12)20)19(18(24)22-25)9-13-11-21-23(17(13)10-19)14-5-2-3-6-14/h4,7-8,11,14,25H,2-3,5-6,9-10H2,1H3,(H,22,24)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272083 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- (pyra...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1cnccn1)C(=O)NO |r| Show InChI InChI=1S/C18H16FN5O2/c1-11-13(3-2-4-14(11)19)18(17(25)23-26)7-12-9-22-24(15(12)8-18)16-10-20-5-6-21-16/h2-6,9-10,26H,7-8H2,1H3,(H,23,25)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272073 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(p- to...) Show SMILES Cc1ccc(cc1)-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H20FN3O2/c1-13-6-8-16(9-7-13)25-19-11-21(20(26)24-27,10-15(19)12-23-25)17-4-3-5-18(22)14(17)2/h3-9,12,27H,10-11H2,1-2H3,(H,24,26)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272133 ((R)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(1- me...) Show SMILES Cc1c(F)cccc1[C@]1(Cc2nc(sc2C1)-c1ccnn1C)C(=O)NO |r| Show InChI InChI=1S/C18H17FN4O2S/c1-10-11(4-3-5-12(10)19)18(17(24)22-25)8-13-15(9-18)26-16(21-13)14-6-7-20-23(14)2/h3-7,25H,8-9H2,1-2H3,(H,22,24)/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272086 ((S)-5-(3-Fluoro-2-methylphenyl)-1-(4-fluoro-2- met...) Show SMILES Cc1cc(F)ccc1-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H19F2N3O2/c1-12-8-15(22)6-7-18(12)26-19-10-21(20(27)25-28,9-14(19)11-24-26)16-4-3-5-17(23)13(16)2/h3-8,11,28H,9-10H2,1-2H3,(H,25,27)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272070 ((S)-5-(3-Fluoro-2-methylphenyl)-1-(3-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1cccc(F)c1)C(=O)NO |r| Show InChI InChI=1S/C20H17F2N3O2/c1-12-16(6-3-7-17(12)22)20(19(26)24-27)9-13-11-23-25(18(13)10-20)15-5-2-4-14(21)8-15/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272157 ((S)-1-Benzyl-5-(3-fluoro-2-methylphenyl)-N-hydroxy...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(Cc3ccccc3)c2C1)C(=O)NO |r| Show InChI InChI=1S/C21H20FN3O2/c1-14-17(8-5-9-18(14)22)21(20(26)24-27)10-16-12-23-25(19(16)11-21)13-15-6-3-2-4-7-15/h2-9,12,27H,10-11,13H2,1H3,(H,24,26)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272122 ((S)-1-Cyclopropyl-5-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(C3CC3)c2C1)C(=O)NO |r| Show InChI InChI=1S/C17H18FN3O2/c1-10-13(3-2-4-14(10)18)17(16(22)20-23)7-11-9-19-21(12-5-6-12)15(11)8-17/h2-4,9,12,23H,5-8H2,1H3,(H,20,22)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272154 ((R)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(5- fl...) Show SMILES Cc1c(F)cccc1[C@]1(Cc2nc(sc2C1)-c1ccc(F)cn1)C(=O)NO |r| Show InChI InChI=1S/C19H15F2N3O2S/c1-10-12(3-2-4-13(10)21)19(18(25)24-26)7-15-16(8-19)27-17(23-15)14-6-5-11(20)9-22-14/h2-6,9,26H,7-8H2,1H3,(H,24,25)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272143 ((R)-5-(3-Fluoro-2-methylphenyl)-3-(4-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2nn(C)c(c2C1)-c1ccc(F)cc1)C(=O)NO |r| Show InChI InChI=1S/C21H19F2N3O2/c1-12-16(4-3-5-17(12)23)21(20(27)25-28)10-15-18(11-21)24-26(2)19(15)13-6-8-14(22)9-7-13/h3-9,28H,10-11H2,1-2H3,(H,25,27)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272069 ((S)-5-(3-Fluoro-2-methylphenyl)-1-(4-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(F)cc1)C(=O)NO |r| Show InChI InChI=1S/C20H17F2N3O2/c1-12-16(3-2-4-17(12)22)20(19(26)24-27)9-13-11-23-25(18(13)10-20)15-7-5-14(21)6-8-15/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272091 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(3- me...) Show SMILES Cc1cnccc1-n1cc2C[C@@](Cc2n1)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C20H19FN4O2/c1-12-10-22-7-6-18(12)25-11-14-8-20(19(26)24-27,9-17(14)23-25)15-4-3-5-16(21)13(15)2/h3-7,10-11,27H,8-9H2,1-2H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272090 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-(3- me...) Show SMILES Cc1cnccc1-n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C20H19FN4O2/c1-12-10-22-7-6-17(12)25-18-9-20(19(26)24-27,8-14(18)11-23-25)15-4-3-5-16(21)13(15)2/h3-7,10-11,27H,8-9H2,1-2H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272068 ((S)-1-(3-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1cccc(Cl)c1)C(=O)NO |r| Show InChI InChI=1S/C20H17ClFN3O2/c1-12-16(6-3-7-17(12)22)20(19(26)24-27)9-13-11-23-25(18(13)10-20)15-5-2-4-14(21)8-15/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272092 ((S)-2-(3-Chloropyridin-2-yl)-5-(3-fluoro-2- methyl...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ncccc1Cl)C(=O)NO |r| Show InChI InChI=1S/C19H16ClFN4O2/c1-11-13(4-2-6-15(11)21)19(18(26)24-27)8-12-10-25(23-16(12)9-19)17-14(20)5-3-7-22-17/h2-7,10,27H,8-9H2,1H3,(H,24,26)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272117 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-1- isopr...) Show SMILES CC(C)n1ncc2C[C@@](Cc12)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C17H20FN3O2/c1-10(2)21-15-8-17(16(22)20-23,7-12(15)9-19-21)13-5-4-6-14(18)11(13)3/h4-6,9-10,23H,7-8H2,1-3H3,(H,20,22)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272140 (E1-(abs)-2-(1,5-Dimethyl-1H-pyrazol-4-yl)-5-(3- fl...) Show SMILES Cc1c(cnn1C)-c1nc2CC(Cc2s1)(C(=O)NO)c1cccc(F)c1C Show InChI InChI=1S/C19H19FN4O2S/c1-10-13(5-4-6-14(10)20)19(18(25)23-26)7-15-16(8-19)27-17(22-15)12-9-21-24(3)11(12)2/h4-6,9,26H,7-8H2,1-3H3,(H,23,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272118 ((R)-4-(3-Fluoro-2-methylphenyl)-N-hydroxy-1-phenyl...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2c1cnn2-c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C20H18FN3O2/c1-13-15(8-5-9-17(13)21)20(19(25)23-26)11-10-18-16(20)12-22-24(18)14-6-3-2-4-7-14/h2-9,12,26H,10-11H2,1H3,(H,23,25)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272089 ((S)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(m- to...) Show SMILES Cc1cccc(c1)-n1cc2C[C@@](Cc2n1)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H20FN3O2/c1-13-5-3-6-16(9-13)25-12-15-10-21(20(26)24-27,11-19(15)23-25)17-7-4-8-18(22)14(17)2/h3-9,12,27H,10-11H2,1-2H3,(H,24,26)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272144 (E1-(abs)-5-(3-fluoro-2-methylphenyl)-N-hydroxy-3- ...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2snc(c2C1)-c1ccccc1)C(=O)NO |r| Show InChI InChI=1S/C20H17FN2O2S/c1-12-15(8-5-9-16(12)21)20(19(24)22-25)10-14-17(11-20)26-23-18(14)13-6-3-2-4-7-13/h2-9,25H,10-11H2,1H3,(H,22,24)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272130 ((R)-5-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@]1(Cc2nc(sc2C1)-c1ccc(F)cc1)C(=O)NO |r| Show InChI InChI=1S/C20H16F2N2O2S/c1-11-14(3-2-4-15(11)22)20(19(25)24-26)9-16-17(10-20)27-18(23-16)12-5-7-13(21)8-6-12/h2-8,26H,9-10H2,1H3,(H,24,25)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272136 ((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2nc(sc12)C1CC1)C(=O)NO |r| Show InChI InChI=1S/C17H17FN2O2S/c1-9-11(3-2-4-12(9)18)17(16(21)20-22)8-7-13-14(17)23-15(19-13)10-5-6-10/h2-4,10,22H,5-8H2,1H3,(H,20,21)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272135 ((R)-5-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(5- me...) Show SMILES COc1ccc(nc1)-c1nc2C[C@](Cc2s1)(C(=O)NO)c1cccc(F)c1C |r| Show InChI InChI=1S/C20H18FN3O3S/c1-11-13(4-3-5-14(11)21)20(19(25)24-26)8-16-17(9-20)28-18(23-16)15-7-6-12(27-2)10-22-15/h3-7,10,26H,8-9H2,1-2H3,(H,24,25)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272123 ((R)-1-Cyclopropyl-4-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2c1cnn2C1CC1)C(=O)NO |r| Show InChI InChI=1S/C17H18FN3O2/c1-10-12(3-2-4-14(10)18)17(16(22)20-23)8-7-15-13(17)9-19-21(15)11-5-6-11/h2-4,9,11,23H,5-8H2,1H3,(H,20,22)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272113 ((R)-2-(2-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2nc(ncc12)-c1ccccc1Cl)C(=O)NO |r| Show InChI InChI=1S/C21H17ClFN3O2/c1-12-14(6-4-8-17(12)23)21(20(27)26-28)10-9-18-15(21)11-24-19(25-18)13-5-2-3-7-16(13)22/h2-8,11,28H,9-10H2,1H3,(H,26,27)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272093 ((S)-5-(3-Fluoro-2-methylphenyl)-2-(3-fluoropyridin...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ncccc1F)C(=O)NO |r| Show InChI InChI=1S/C19H16F2N4O2/c1-11-13(4-2-5-14(11)20)19(18(26)24-27)8-12-10-25(23-16(12)9-19)17-15(21)6-3-7-22-17/h2-7,10,27H,8-9H2,1H3,(H,24,26)/t19-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272084 ((S)-1-(4-(Difluoromethoxy)phenyl)-5-(3-fluoro-2- m...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(OC(F)F)cc1)C(=O)NO |r| Show InChI InChI=1S/C21H18F3N3O3/c1-12-16(3-2-4-17(12)22)21(19(28)26-29)9-13-11-25-27(18(13)10-21)14-5-7-15(8-6-14)30-20(23)24/h2-8,11,20,29H,9-10H2,1H3,(H,26,28)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272146 (2-(3-Fluoro-2-methylphenyl)-N-hydroxy-2,3-dihydro-...) Show SMILES Cc1c(F)cccc1C1(Cc2ccccc2C1)C(=O)NO Show InChI InChI=1S/C17H16FNO2/c1-11-14(7-4-8-15(11)18)17(16(20)19-21)9-12-5-2-3-6-13(12)10-17/h2-8,21H,9-10H2,1H3,(H,19,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272072 ((S)-1-(4-Chlorophenyl)-5-(3-fluoro-2-methylphenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnn(c2C1)-c1ccc(Cl)cc1)C(=O)NO |r| Show InChI InChI=1S/C20H17ClFN3O2/c1-12-16(3-2-4-17(12)22)20(19(26)24-27)9-13-11-23-25(18(13)10-20)15-7-5-14(21)6-8-15/h2-8,11,27H,9-10H2,1H3,(H,24,26)/t20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272142 ((S)-6-(3-Fluoro-2-methylphenyl)-2-(4-fluorophenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(CCc2nc(sc12)-c1ccc(F)cc1)C(=O)NO |r| Show InChI InChI=1S/C20H16F2N2O2S/c1-11-14(3-2-4-15(11)22)20(19(25)24-26)10-9-16-17(20)27-18(23-16)12-5-7-13(21)8-6-12/h2-8,26H,9-10H2,1H3,(H,24,25)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272134 ((R)-2-(1,3-Dimethyl-1H-pyrazol-5-yl)-5-(3-fluoro-2...) Show SMILES Cc1cc(-c2nc3C[C@](Cc3s2)(C(=O)NO)c2cccc(F)c2C)n(C)n1 |r| Show InChI InChI=1S/C19H19FN4O2S/c1-10-7-15(24(3)22-10)17-21-14-8-19(18(25)23-26,9-16(14)27-17)12-5-4-6-13(20)11(12)2/h4-7,26H,8-9H2,1-3H3,(H,23,25)/t19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272137 ((S)-6-(3-Fluoro-2-methylphenyl)-N-hydroxy-2-(o- to...) Show SMILES Cc1ccccc1-c1nc2CC[C@](C(=O)NO)(c2s1)c1cccc(F)c1C |r| Show InChI InChI=1S/C21H19FN2O2S/c1-12-6-3-4-7-14(12)19-23-17-10-11-21(18(17)27-19,20(25)24-26)15-8-5-9-16(22)13(15)2/h3-9,26H,10-11H2,1-2H3,(H,24,25)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272085 ((S)-2-(4-(Difluoromethoxy)phenyl)-5-(3-fluoro-2- m...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cn(nc2C1)-c1ccc(OC(F)F)cc1)C(=O)NO |r| Show InChI InChI=1S/C21H18F3N3O3/c1-12-16(3-2-4-17(12)22)21(19(28)26-29)9-13-11-27(25-18(13)10-21)14-5-7-15(8-6-14)30-20(23)24/h2-8,11,20,29H,9-10H2,1H3,(H,26,28)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272112 ((S)-2-(2-Chlorophenyl)-6-(3-fluoro-2-methylphenyl)...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnc(nc2C1)-c1ccccc1Cl)C(=O)NO |r| Show InChI InChI=1S/C21H17ClFN3O2/c1-12-15(6-4-8-17(12)23)21(20(27)26-28)9-13-11-24-19(25-18(13)10-21)14-5-2-3-7-16(14)22/h2-8,11,28H,9-10H2,1H3,(H,26,27)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair
Histone deacetylase 9 (Homo sapiens (Human))	BDBM272116 ((S)-2-Cyclopropyl-6-(3-fluoro-2-methylphenyl)-N- h...) Show SMILES Cc1c(F)cccc1[C@@]1(Cc2cnc(nc2C1)C1CC1)C(=O)NO |r| Show InChI InChI=1S/C18H18FN3O2/c1-10-13(3-2-4-14(10)19)18(17(23)22-24)7-12-9-20-16(11-5-6-11)21-15(12)8-18/h2-4,9,11,24H,5-8H2,1H3,(H,22,23)/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
CHDI Foundation, Inc. US Patent					Assay Description The potency of the compounds is quantified by measuring the Histone Deacetylase 9 (HDAC9) enzymatic activity using the fluorogenic substrate, Boc-Lys...				US Patent US10065948 (2018) BindingDB Entry DOI: 10.7270/Q2154K23
					More data for this Ligand-Target Pair

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