Compile Data Set for Download or QSAR

Found 484 hits Enz. Inhib. hit(s) with all data for entry = 1745   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338101 (US9751854, Compound I-277) Show SMILES CN(C(=O)c1cc(cnc1N)-c1ccnc(Nc2ccnc(C)n2)c1)C12CC(C1)C2 Show InChI InChI=1S/C22H23N7O/c1-13-24-6-4-18(27-13)28-19-8-15(3-5-25-19)16-7-17(20(23)26-12-16)21(30)29(2)22-9-14(10-22)11-22/h3-8,12,14H,9-11H2,1-2H3,(H2,23,26)(H,24,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338106 (US9751854, Compound I-282 | US9802960, Compound I-...) Show SMILES Cc1c(NS(=O)(=O)c2ccc(F)cc2F)c(Cl)ncc1-c1ccnc(Nc2ccncn2)c1 Show InChI InChI=1S/C21H15ClF2N6O2S/c1-12-15(13-4-7-26-19(8-13)29-18-5-6-25-11-28-18)10-27-21(22)20(12)30-33(31,32)17-3-2-14(23)9-16(17)24/h2-11,30H,1H3,(H,25,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338110 (US9751854, Compound I-286 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1C)-c1ccnc(Nc2ccnc(C)n2)c1 Show InChI InChI=1S/C18H21N7O2S/c1-12-16(24-28(26,27)25(3)4)9-15(11-21-12)14-5-7-20-18(10-14)23-17-6-8-19-13(2)22-17/h5-11,24H,1-4H3,(H,19,20,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338113 (US9751854, Compound I-289 | US9802960, Compound I-...) Show SMILES Cc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccnc(Nc2ccc(C#N)c(C)n2)c1 Show InChI InChI=1S/C24H18F2N6O2S/c1-14-17(12-27)3-6-23(30-14)31-24-10-16(7-8-28-24)18-9-21(15(2)29-13-18)32-35(33,34)22-5-4-19(25)11-20(22)26/h3-11,13,32H,1-2H3,(H,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338115 (US9751854, Compound I-291 | US9802960, Compound I-...) Show SMILES Cc1nccc(Nc2cc(ccn2)-c2cnc(C)c(NS(=O)(=O)c3ccc(F)cc3F)c2)n1 Show InChI InChI=1S/C22H18F2N6O2S/c1-13-19(30-33(31,32)20-4-3-17(23)11-18(20)24)9-16(12-27-13)15-5-7-26-22(10-15)29-21-6-8-25-14(2)28-21/h3-12,30H,1-2H3,(H,25,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338117 (US9751854, Compound I-293 | US9802960, Compound I-...) Show SMILES Cc1ccnc(Nc2cc(ccn2)-c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3F)c2C)n1 Show InChI InChI=1S/C22H17ClF2N6O2S/c1-12-5-7-27-22(29-12)30-19-9-14(6-8-26-19)16-11-28-21(23)20(13(16)2)31-34(32,33)18-4-3-15(24)10-17(18)25/h3-11,31H,1-2H3,(H,26,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338118 (US9751854, Compound I-294 | US9802960, Compound I-...) Show SMILES Cc1nccc(Nc2cc(c(F)cn2)-c2cnc(Cl)c(NS(=O)(=O)c3ccc(F)cc3F)c2C)n1 Show InChI InChI=1S/C22H16ClF3N6O2S/c1-11-15(14-8-20(28-10-17(14)26)31-19-5-6-27-12(2)30-19)9-29-22(23)21(11)32-35(33,34)18-4-3-13(24)7-16(18)25/h3-10,32H,1-2H3,(H,27,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338122 (US9751854, Compound I-298 | US9751854, Compound I-...) Show SMILES CN(C(=O)c1cc(cnc1N)-c1ccnc(Nc2ccncn2)c1)C12CC(C1)C2 Show InChI InChI=1S/C21H21N7O/c1-28(21-8-13(9-21)10-21)20(29)16-6-15(11-25-19(16)22)14-2-5-24-18(7-14)27-17-3-4-23-12-26-17/h2-7,11-13H,8-10H2,1H3,(H2,22,25)(H,23,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338132 (US9751854, Compound I-308 | US9802960, Compound I-...) Show SMILES Cc1c(NS(=O)(=O)c2ccc(F)cc2F)c(Cl)ncc1-c1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C21H17ClF2N4O3S/c1-11-15(13-6-7-25-18(8-13)27-21(29)12-2-3-12)10-26-20(22)19(11)28-32(30,31)17-5-4-14(23)9-16(17)24/h4-10,12,28H,2-3H2,1H3,(H,25,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338133 (US9751854, Compound I-309 | US9802960, Compound I-...) Show SMILES Cc1c(NS(=O)(=O)c2ccccc2)c(Cl)ncc1-c1ccnc(Nc2ccncn2)c1 Show InChI InChI=1S/C21H17ClN6O2S/c1-14-17(15-7-10-24-19(11-15)27-18-8-9-23-13-26-18)12-25-21(22)20(14)28-31(29,30)16-5-3-2-4-6-16/h2-13,28H,1H3,(H,23,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338134 (US9751854, Compound I-310 | US9802960, Compound I-...) Show SMILES Cc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccnc(Nc2cnccn2)c1 Show InChI InChI=1S/C21H16F2N6O2S/c1-13-18(29-32(30,31)19-3-2-16(22)10-17(19)23)8-15(11-27-13)14-4-5-25-20(9-14)28-21-12-24-6-7-26-21/h2-12,29H,1H3,(H,25,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338135 (US9751854, Compound I-311 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1C)-c1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C17H21N5O3S/c1-11-15(21-26(24,25)22(2)3)8-14(10-19-11)13-6-7-18-16(9-13)20-17(23)12-4-5-12/h6-10,12,21H,4-5H2,1-3H3,(H,18,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338148 (US9751854, Compound I-326 | US9802960, Compound I-...) Show SMILES Cc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccnc(NC(=O)OCc2ccn(C)n2)c1 Show InChI InChI=1S/C23H20F2N6O4S/c1-14-20(30-36(33,34)21-4-3-17(24)11-19(21)25)9-16(12-27-14)15-5-7-26-22(10-15)28-23(32)35-13-18-6-8-31(2)29-18/h3-12,30H,13H2,1-2H3,(H,26,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338164 (US9751854, Compound I-342) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2cccc(Cl)c2Cl)c1 Show InChI InChI=1S/C19H16Cl2N4O3S/c1-11-16(25-29(27,28)17-5-3-4-15(20)19(17)21)8-14(10-23-11)13-6-7-22-18(9-13)24-12(2)26/h3-10,25H,1-2H3,(H,22,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338171 (US9751854, Compound I-350 | US9802960, Compound I-...) Show SMILES CCCCN(CCCC)S(=O)(=O)Nc1cc(cnc1C)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C21H31N5O3S/c1-5-7-11-26(12-8-6-2)30(28,29)25-20-13-19(15-23-16(20)3)18-9-10-22-21(14-18)24-17(4)27/h9-10,13-15,25H,5-8,11-12H2,1-4H3,(H,22,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338176 (US9751854, Compound I-356 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccc(cc2F)C#N)c1 Show InChI InChI=1S/C20H16FN5O3S/c1-12-18(26-30(28,29)19-4-3-14(10-22)7-17(19)21)8-16(11-24-12)15-5-6-23-20(9-15)25-13(2)27/h3-9,11,26H,1-2H3,(H,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338190 (US9751854, Compound I-371) Show SMILES CC(=O)Nc1cc(cn2nccc12)-c1ccnc(Nc2ccnc(n2)C2CC2)c1 Show InChI InChI=1S/C21H19N7O/c1-13(29)25-17-10-16(12-28-18(17)5-9-24-28)15-4-7-22-20(11-15)26-19-6-8-23-21(27-19)14-2-3-14/h4-12,14H,2-3H2,1H3,(H,25,29)(H,22,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338191 (US9751854, Compound I-372) Show SMILES CN(C)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C14H16ClN5O3S/c1-9(21)18-13-7-10(4-5-16-13)11-6-12(14(15)17-8-11)19-24(22,23)20(2)3/h4-8,19H,1-3H3,(H,16,18,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338194 (US9751854, Compound I-375 | US9802960, Compound I-...) Show SMILES COc1nc(C)nc(Nc2cc(ccn2)-c2cnc(C)c(NS(=O)(=O)c3ccc(F)cc3F)c2)n1 Show InChI InChI=1S/C22H19F2N7O3S/c1-12-18(31-35(32,33)19-5-4-16(23)10-17(19)24)8-15(11-26-12)14-6-7-25-20(9-14)29-21-27-13(2)28-22(30-21)34-3/h4-11,31H,1-3H3,(H,25,27,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338200 (US9751854, Compound I-381 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)Nc1c(Cl)ncc(c1C)-c1ccnc(Nc2ccnc(C)n2)c1 Show InChI InChI=1S/C18H20ClN7O2S/c1-11-14(10-22-18(19)17(11)25-29(27,28)26(3)4)13-5-7-21-16(9-13)24-15-6-8-20-12(2)23-15/h5-10,25H,1-4H3,(H,20,21,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338201 (US9751854, Compound I-382 | US9802960, Compound I-...) Show SMILES Cc1nc(Nc2cc(ccn2)-c2cnc(C)c(NS(=O)(=O)c3ccc(F)cc3F)c2)nc(n1)C1CC1 Show InChI InChI=1S/C24H21F2N7O2S/c1-13-20(33-36(34,35)21-6-5-18(25)11-19(21)26)9-17(12-28-13)16-7-8-27-22(10-16)31-24-30-14(2)29-23(32-24)15-3-4-15/h5-12,15,33H,3-4H2,1-2H3,(H,27,29,30,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338207 (US9751854, Compound I-389 | US9802960, Compound I-...) Show SMILES CCOC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C20H18F2N4O4S/c1-3-30-20(27)25-19-9-13(6-7-23-19)14-8-17(12(2)24-11-14)26-31(28,29)18-5-4-15(21)10-16(18)22/h4-11,26H,3H2,1-2H3,(H,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338217 (US9751854, Compound I-401 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(Cl)c(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1C Show InChI InChI=1S/C19H15Cl3N4O3S/c1-10-14(12-5-6-23-17(7-12)25-11(2)27)9-24-19(22)18(10)26-30(28,29)16-8-13(20)3-4-15(16)21/h3-9,26H,1-2H3,(H,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338227 (US9751854, Compound I-411 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C#N)c(NS(=O)(=O)c2ccc(F)cc2F)c1 Show InChI InChI=1S/C19H13F2N5O3S/c1-11(27)25-19-7-12(4-5-23-19)13-6-16(17(9-22)24-10-13)26-30(28,29)18-3-2-14(20)8-15(18)21/h2-8,10,26H,1H3,(H,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337926 (US9751854, Compound I-107 | US9802960, Compound I-...) Show SMILES COc1ncc(cc1S(=O)(=O)Nc1ccc(F)cc1F)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C19H16F2N4O4S/c1-11(26)24-18-8-12(5-6-22-18)13-7-17(19(29-2)23-10-13)30(27,28)25-16-4-3-14(20)9-15(16)21/h3-10,25H,1-2H3,(H,22,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM338028 (US9751854, Compound I-204 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(N)c(c1)S(=O)(=O)Nc1cccnc1 Show InChI InChI=1S/C17H16N6O3S/c1-11(24)22-16-8-12(4-6-20-16)13-7-15(17(18)21-9-13)27(25,26)23-14-3-2-5-19-10-14/h2-10,23H,1H3,(H2,18,21)(H,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337929 (US9751854, Compound I-110 | US9802960, Compound I-...) Show SMILES CN(CC1CC1)S(=O)(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C17H21N5O3S/c1-11(23)21-16-8-13(5-6-19-16)14-7-15(17(18)20-9-14)26(24,25)22(2)10-12-3-4-12/h5-9,12H,3-4,10H2,1-2H3,(H2,18,20)(H,19,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337930 (US9751854, Compound I-111 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1 Show InChI InChI=1S/C19H16Cl2N4O3S/c1-11-17(25-29(27,28)18-9-15(20)3-4-16(18)21)7-14(10-23-11)13-5-6-22-19(8-13)24-12(2)26/h3-10,25H,1-2H3,(H,22,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337932 (US9751854, Compound I-113 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2Cl)c1 Show InChI InChI=1S/C20H16ClF3N4O4S/c1-11-17(7-14(10-26-11)13-5-6-25-19(8-13)27-12(2)29)28-33(30,31)18-4-3-15(9-16(18)21)32-20(22,23)24/h3-10,28H,1-2H3,(H,25,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337943 (US9751854, Compound I-119 | US9802960, Compound I-...) Show SMILES CN(C)S(=O)(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C14H17N5O3S/c1-9(20)18-13-7-10(4-5-16-13)11-6-12(14(15)17-8-11)23(21,22)19(2)3/h4-8H,1-3H3,(H2,15,17)(H,16,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337944 (US9751854, Compound I-120 | US9802960, Compound I-...) Show SMILES CCN(CC)S(=O)(=O)c1cncc(c1)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C16H20N4O3S/c1-4-20(5-2)24(22,23)15-8-14(10-17-11-15)13-6-7-18-16(9-13)19-12(3)21/h6-11H,4-5H2,1-3H3,(H,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337947 (US9751854, Compound I-123 | US9802960, Compound I-...) Show SMILES COc1cccc(c1)S(=O)(=O)Nc1cc(cnc1C)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C20H20N4O4S/c1-13-19(24-29(26,27)18-6-4-5-17(11-18)28-3)9-16(12-22-13)15-7-8-21-20(10-15)23-14(2)25/h4-12,24H,1-3H3,(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337948 (US9751854, Compound I-124 | US9802960, Compound I-...) Show SMILES CCN(CC)S(=O)(=O)c1cc(cnc1N)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C16H21N5O3S/c1-4-21(5-2)25(23,24)14-8-13(10-19-16(14)17)12-6-7-18-15(9-12)20-11(3)22/h6-10H,4-5H2,1-3H3,(H2,17,19)(H,18,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337949 (US9751854, Compound I-125 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(N)c(c1)C(=O)N1Cc2ccccc2C1 Show InChI InChI=1S/C21H19N5O2/c1-13(27)25-19-9-14(6-7-23-19)17-8-18(20(22)24-10-17)21(28)26-11-15-4-2-3-5-16(15)12-26/h2-10H,11-12H2,1H3,(H2,22,24)(H,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337952 (US9751854, Compound I-128 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccc(C)cc2Cl)c1 Show InChI InChI=1S/C20H19ClN4O3S/c1-12-4-5-19(17(21)8-12)29(27,28)25-18-9-16(11-23-13(18)2)15-6-7-22-20(10-15)24-14(3)26/h4-11,25H,1-3H3,(H,22,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337955 (US9751854, Compound I-131 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1 Show InChI InChI=1S/C23H26N4O3S/c1-15-21(27-31(29,30)20-8-6-19(7-9-20)23(3,4)5)12-18(14-25-15)17-10-11-24-22(13-17)26-16(2)28/h6-14,27H,1-5H3,(H,24,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337956 (US9751854, Compound I-132 | US9802960, Compound I-...) Show SMILES CNc1ncc(cc1N1CCCS1(=O)=O)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C16H19N5O3S/c1-11(22)20-15-9-12(4-5-18-15)13-8-14(16(17-2)19-10-13)21-6-3-7-25(21,23)24/h4-5,8-10H,3,6-7H2,1-2H3,(H,17,19)(H,18,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337957 (US9751854, Compound I-133 | US9802960, Compound I-...) Show SMILES CN(c1cc(cnc1N)-c1ccnc(NC(C)=O)c1)S(C)(=O)=O Show InChI InChI=1S/C14H17N5O3S/c1-9(20)18-13-7-10(4-5-16-13)11-6-12(14(15)17-8-11)19(2)23(3,21)22/h4-8H,1-3H3,(H2,15,17)(H,16,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337960 (US9751854, Compound I-136 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(N)c(c1)C(=O)Nc1ccccc1Cl Show InChI InChI=1S/C19H16ClN5O2/c1-11(26)24-17-9-12(6-7-22-17)13-8-14(18(21)23-10-13)19(27)25-16-5-3-2-4-15(16)20/h2-10H,1H3,(H2,21,23)(H,25,27)(H,22,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337965 (US9751854, Compound I-141 | US9802960, Compound I-...) Show SMILES CNc1ncc(cc1N(CC1CC1)S(C)(=O)=O)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C18H23N5O3S/c1-12(24)22-17-9-14(6-7-20-17)15-8-16(18(19-2)21-10-15)23(27(3,25)26)11-13-4-5-13/h6-10,13H,4-5,11H2,1-3H3,(H,19,21)(H,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337966 (US9751854, Compound I-142 | US9802960, Compound I-...) Show SMILES COc1cc(C)ccc1S(=O)(=O)Nc1cc(cnc1C)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C21H22N4O4S/c1-13-5-6-20(19(9-13)29-4)30(27,28)25-18-10-17(12-23-14(18)2)16-7-8-22-21(11-16)24-15(3)26/h5-12,25H,1-4H3,(H,22,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337967 (US9751854, Compound I-143 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2cc(ccc2F)C(F)(F)F)c1 Show InChI InChI=1S/C20H16F4N4O3S/c1-11-17(7-14(10-26-11)13-5-6-25-19(8-13)27-12(2)29)28-32(30,31)18-9-15(20(22,23)24)3-4-16(18)21/h3-10,28H,1-2H3,(H,25,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337968 (US9751854, Compound I-144 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccccc2F)c1 Show InChI InChI=1S/C19H17FN4O3S/c1-12-17(24-28(26,27)18-6-4-3-5-16(18)20)9-15(11-22-12)14-7-8-21-19(10-14)23-13(2)25/h3-11,24H,1-2H3,(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337971 (US9751854, Compound I-147 | US9802960, Compound I-...) Show SMILES CNc1ncc(cc1N(C)S(C)(=O)=O)-c1ccnc(NC(C)=O)c1 Show InChI InChI=1S/C15H19N5O3S/c1-10(21)19-14-8-11(5-6-17-14)12-7-13(15(16-2)18-9-12)20(3)24(4,22)23/h5-9H,1-4H3,(H,16,18)(H,17,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337974 (US9751854, Compound I-150 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2c(F)cccc2F)c1 Show InChI InChI=1S/C19H16F2N4O3S/c1-11-17(25-29(27,28)19-15(20)4-3-5-16(19)21)8-14(10-23-11)13-6-7-22-18(9-13)24-12(2)26/h3-10,25H,1-2H3,(H,22,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337977 (US9751854, Compound I-153 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(Cl)c(NS(=O)(=O)c2ccc(F)cc2F)c1C Show InChI InChI=1S/C19H15ClF2N4O3S/c1-10-14(12-5-6-23-17(7-12)25-11(2)27)9-24-19(20)18(10)26-30(28,29)16-4-3-13(21)8-15(16)22/h3-9,26H,1-2H3,(H,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337978 (US9751854, Compound I-154 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H17ClN4O3S/c1-12-18(24-28(26,27)17-5-3-16(20)4-6-17)9-15(11-22-12)14-7-8-21-19(10-14)23-13(2)25/h3-11,24H,1-2H3,(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337979 (US9751854, Compound I-155 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(C)c(NS(=O)(=O)c2cccc(F)c2)c1 Show InChI InChI=1S/C19H17FN4O3S/c1-12-18(24-28(26,27)17-5-3-4-16(20)10-17)8-15(11-22-12)14-6-7-21-19(9-14)23-13(2)25/h3-11,24H,1-2H3,(H,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337980 (US9751854, Compound I-156 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc(N)c(c1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C17H21N5O3S/c1-12(23)21-16-10-13(5-6-19-16)14-9-15(17(18)20-11-14)26(24,25)22-7-3-2-4-8-22/h5-6,9-11H,2-4,7-8H2,1H3,(H2,18,20)(H,19,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3 (Homo sapiens (Human))	BDBM337982 (US9751854, Compound I-158 | US9802960, Compound I-...) Show SMILES CC(=O)Nc1cc(ccn1)-c1cnc2[nH]cc(c2c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C18H19N5O3S/c1-12(24)22-17-9-13(4-5-19-17)14-8-15-16(11-21-18(15)20-10-14)27(25,26)23-6-2-3-7-23/h4-5,8-11H,2-3,6-7H2,1H3,(H,20,21)(H,19,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. US Patent					Assay Description 100 nL compounds in DMSO are added to wells of a 384 well microtitre plate (Greiner 780076). At room temperature: 5 ul VPS34 reaction buffer (Invitro...				US Patent US9751854 (2017) BindingDB Entry DOI: 10.7270/Q2KS6TNJ
					More data for this Ligand-Target Pair

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