BindingDB logo
myBDB logout

Patent code US9085549

Compile Data Set for Download or QSAR
Found 48 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-synuclein


(Homo sapiens (Human))		BDBM170546
PNG
(US9085549, 57 | US9085549, 64)
Show SMILES Oc1ccc(cc1O)-c1nsc(n1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O4S/c17-9-3-1-7(5-11(9)19)13-15-14(21-16-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 89n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170553
PNG
(US9085549, 58)
Show SMILES Oc1ccc(cc1O)-c1ccc(s1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C16H12O4S/c17-11-3-1-9(7-13(11)19)15-5-6-16(21-15)10-2-4-12(18)14(20)8-10/h1-8,17-20H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 105n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170546
PNG
(US9085549, 57 | US9085549, 64)
Show SMILES Oc1ccc(cc1O)-c1nsc(n1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O4S/c17-9-3-1-7(5-11(9)19)13-15-14(21-16-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 124n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170556
PNG
(US9085549, 66)
Show SMILES Oc1ccc(cc1O)-c1nnc(s1)-c1cc(O)c(O)cc1Br
Show InChI InChI=1S/C14H9BrN2O4S/c15-8-5-12(21)11(20)4-7(8)14-17-16-13(22-14)6-1-2-9(18)10(19)3-6/h1-5,18-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 135n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170564
PNG
(US9085549, 82)
Show SMILES Oc1ccc(cc1O)-c1cnc(s1)-c1cc(O)c(O)cc1Br
Show InChI InChI=1S/C15H10BrNO4S/c16-9-5-13(21)12(20)4-8(9)15-17-6-14(22-15)7-1-2-10(18)11(19)3-7/h1-6,18-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 177n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170562
PNG
(US9085549, 76)
Show SMILES COc1cc(ccc1O)-c1nnc(s1)-c1cc(O)c(O)cc1I
Show InChI InChI=1S/C15H11IN2O4S/c1-22-13-4-7(2-3-10(13)19)14-17-18-15(23-14)8-5-11(20)12(21)6-9(8)16/h2-6,19-21H,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 219n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170545
PNG
(US9085549, 86)
Show SMILES Oc1ccc(cc1O)-c1ncc(s1)-c1cc(O)c(O)cc1Br
Show InChI InChI=1S/C15H10BrNO4S/c16-9-5-13(21)12(20)4-8(9)14-6-17-15(22-14)7-1-2-10(18)11(19)3-7/h1-6,18-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 224n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170561
PNG
(US9085549, 72)
Show SMILES Oc1ccc(cc1O)-c1nnc(s1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O4S/c17-9-3-1-7(5-11(9)19)13-15-16-14(21-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 270n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170547
PNG
(US9085549, 63)
Show SMILES Oc1ccc(cc1O)-c1ccc(s1)-c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C16H12O5S/c17-10-2-1-8(5-11(10)18)14-3-4-15(22-14)9-6-12(19)16(21)13(20)7-9/h1-7,17-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 283n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170563
PNG
(US9085549, 78)
Show SMILES Oc1ccc(cc1O)-c1ccc(s1)-c1cc(O)c(O)c(I)c1
Show InChI InChI=1S/C16H11IO4S/c17-10-5-9(7-13(20)16(10)21)15-4-3-14(22-15)8-1-2-11(18)12(19)6-8/h1-7,18-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 330n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170565
PNG
(US9085549, 83)
Show SMILES CC(=O)Oc1ccc(cc1OC(C)=O)-c1nnc(s1)-c1cc(OC(C)=O)c(OC(C)=O)cc1I
Show InChI InChI=1S/C22H17IN2O8S/c1-10(26)30-17-6-5-14(7-18(17)31-11(2)27)21-24-25-22(34-21)15-8-19(32-12(3)28)20(9-16(15)23)33-13(4)29/h5-9H,1-4H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 330n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170551
PNG
(US9085549, 55)
Show SMILES Oc1ccc(cc1O)-c1nnc(o1)-c1cc(O)c(O)cc1O
Show InChI InChI=1S/C14H10N2O6/c17-8-2-1-6(3-10(8)19)13-15-16-14(22-13)7-4-11(20)12(21)5-9(7)18/h1-5,17-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 370n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170557
PNG
(US9085549, 67)
Show SMILES Oc1ccc(cc1O)-c1nnc(o1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O5/c17-9-3-1-7(5-11(9)19)13-15-16-14(21-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 466n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170555
PNG
(US9085549, 62)
Show SMILES Oc1ccc(cc1O)-c1ccc(Br)s1
Show InChI InChI=1S/C10H7BrO2S/c11-10-4-3-9(14-10)6-1-2-7(12)8(13)5-6/h1-5,12-13H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 506n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170544
PNG
(US9085549, 79)
Show SMILES CCCC[Sn](CCCC)(CCCC)c1cnc(s1)-c1ccc(OC(C)=O)c(OC(C)=O)c1
Show InChI InChI=1S/C13H10NO4S.3C4H9.Sn/c1-8(15)17-11-4-3-10(13-14-5-6-19-13)7-12(11)18-9(2)16;3*1-3-4-2;/h3-5,7H,1-2H3;3*1,3-4H2,2H3;
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 537n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170566
PNG
(US9085549, 84)
Show SMILES Oc1ccc(cc1O)-c1cnc(o1)-c1cc(O)c(O)cc1Br
Show InChI InChI=1S/C15H10BrNO5/c16-9-5-13(21)12(20)4-8(9)15-17-6-14(22-15)7-1-2-10(18)11(19)3-7/h1-6,18-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 639n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170560
PNG
(US9085549, 70)
Show SMILES Oc1ccc(cc1O)-c1cnc(o1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C15H11NO5/c17-10-3-1-8(5-12(10)19)14-7-16-15(21-14)9-2-4-11(18)13(20)6-9/h1-7,17-20H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 659n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170543
PNG
(US9085549, 59)
Show SMILES Oc1ccc(cc1O)-c1cc(Br)c(s1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C16H11BrO4S/c17-10-7-15(8-1-3-11(18)13(20)5-8)22-16(10)9-2-4-12(19)14(21)6-9/h1-7,18-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 697n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170558
PNG
(US9085549, 68)
Show SMILES Oc1ccc(cc1O)-c1cn(nn1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H11N3O4/c18-11-3-1-8(5-13(11)20)10-7-17(16-15-10)9-2-4-12(19)14(21)6-9/h1-7,18-21H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 697n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170559
PNG
(US9085549, 69)
Show SMILES Oc1ccc(cc1O)-c1ncc(Br)s1
Show InChI InChI=1S/C9H6BrNO2S/c10-8-4-11-9(14-8)5-1-2-6(12)7(13)3-5/h1-4,12-13H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 765n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170549
PNG
(US9085549, 53)
Show SMILES Oc1ccc(NC(=O)c2cc(O)c(O)cc2Br)cc1O
Show InChI InChI=1S/C13H10BrNO5/c14-8-5-12(19)11(18)4-7(8)13(20)15-6-1-2-9(16)10(17)3-6/h1-5,16-19H,(H,15,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 813n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170571
PNG
(US9085549, 95)
Show SMILES Oc1ccc(cc1O)C(=O)\C=C\c1cc(O)c(O)cc1Br
Show InChI InChI=1S/C15H11BrO5/c16-10-7-15(21)14(20)5-8(10)1-3-11(17)9-2-4-12(18)13(19)6-9/h1-7,18-21H/b3-1+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 890n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170568
PNG
(US9085549, 88)
Show SMILES Oc1cc(Cc2cc(O)c(O)cc2N([O-])=O)c(cc1O)N([O-])=O
Show InChI InChI=1S/C13H12N2O8/c16-10-2-6(8(14(20)21)4-12(10)18)1-7-3-11(17)13(19)5-9(7)15(22)23/h2-5,14-15H,1H2,(H4-2,16,17,18,19,20,21,22,23)/q-2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 970n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM50157562
PNG
(1,3-bis(3,4-dihydroxyphenyl)prop-2-en-1-one | 3,3'...)
Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)c(O)c2)cc1O
Show InChI InChI=1S/C15H12O5/c16-11(10-3-6-13(18)15(20)8-10)4-1-9-2-5-12(17)14(19)7-9/h1-8,17-20H/b4-1+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
US Patent
 1.10E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170569
PNG
(US9085549, 89)
Show SMILES Oc1ccc(Cc2cc(O)c(O)cc2C#N)cc1O
Show InChI InChI=1S/C14H11NO4/c15-7-10-6-14(19)13(18)5-9(10)3-8-1-2-11(16)12(17)4-8/h1-2,4-6,16-19H,3H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 1.20E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170548
PNG
(US9085549, 52)
Show SMILES Oc1ccc(cc1O)C(=O)Nc1cc(O)c(O)cc1Br
Show InChI InChI=1S/C13H10BrNO5/c14-7-4-11(18)12(19)5-8(7)15-13(20)6-1-2-9(16)10(17)3-6/h1-5,16-19H,(H,15,20)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 1.26E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170572
PNG
(US9085549, 96)
Show SMILES Oc1ccc(\C=C\C(=O)c2cc(O)c(O)cc2Br)cc1O
Show InChI InChI=1S/C15H11BrO5/c16-10-7-15(21)14(20)6-9(10)11(17)3-1-8-2-4-12(18)13(19)5-8/h1-7,18-21H/b3-1+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 1.35E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170550
PNG
(US9085549, 54)
Show SMILES Oc1ccc(cc1O)-c1nc2cc(O)c(O)cc2o1
Show InChI InChI=1S/C13H9NO5/c15-8-2-1-6(3-9(8)16)13-14-7-4-10(17)11(18)5-12(7)19-13/h1-5,15-18H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 1.64E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170570
PNG
(US9085549, 90)
Show SMILES Oc1ccc(Cc2cc(O)c(O)cc2N([O-])=O)cc1O
Show InChI InChI=1S/C13H12NO6/c15-10-2-1-7(4-11(10)16)3-8-5-12(17)13(18)6-9(8)14(19)20/h1-2,4-6,14H,3H2,(H4-,15,16,17,18,19,20)/q-1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 1.70E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170567
PNG
(US9085549, 87)
Show SMILES Oc1ccc(Cc2cc(O)c(O)cc2Br)cc1O
Show InChI InChI=1S/C13H11BrO4/c14-9-6-13(18)12(17)5-8(9)3-7-1-2-10(15)11(16)4-7/h1-2,4-6,15-18H,3H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 2.00E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Alpha-synuclein


(Homo sapiens (Human))		BDBM170554
PNG
(US9085549, 61)
Show SMILES Oc1ccc(cc1O)-c1cc(c(s1)-c1ccc(O)c(O)c1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H16O6S/c23-15-4-1-11(7-18(15)26)14-10-21(12-2-5-16(24)19(27)8-12)29-22(14)13-3-6-17(25)20(28)9-13/h1-10,23-28H
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
 3.10E+3n/an/an/an/an/an/a7.4n/a



PROTEOTECH INC

US Patent


Assay Description
The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170575
PNG
(US9085549, 99)
Show SMILES Oc1ccc(cc1O)-c1ccc(-c2ccc(O)c(O)c2)c(c1)N(=O)=O
Show InChI InChI=1S/C18H13NO6/c20-15-5-2-11(8-17(15)22)10-1-4-13(14(7-10)19(24)25)12-3-6-16(21)18(23)9-12/h1-9,20-23H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a 2.47E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170550
PNG
(US9085549, 54)
Show SMILES Oc1ccc(cc1O)-c1nc2cc(O)c(O)cc2o1
Show InChI InChI=1S/C13H9NO5/c15-8-2-1-6(3-9(8)16)13-14-7-4-10(17)11(18)5-12(7)19-13/h1-5,15-18H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 7.34E+3n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170571
PNG
(US9085549, 95)
Show SMILES Oc1ccc(cc1O)C(=O)\C=C\c1cc(O)c(O)cc1Br
Show InChI InChI=1S/C15H11BrO5/c16-10-7-15(21)14(20)5-8(10)1-3-11(17)9-2-4-12(18)13(19)6-9/h1-7,18-21H/b3-1+
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 9.02E+3n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170554
PNG
(US9085549, 61)
Show SMILES Oc1ccc(cc1O)-c1cc(c(s1)-c1ccc(O)c(O)c1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C22H16O6S/c23-15-4-1-11(7-18(15)26)14-10-21(12-2-5-16(24)19(27)8-12)29-22(14)13-3-6-17(25)20(28)9-13/h1-10,23-28H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 1.25E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170561
PNG
(US9085549, 72)
Show SMILES Oc1ccc(cc1O)-c1nnc(s1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O4S/c17-9-3-1-7(5-11(9)19)13-15-16-14(21-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 2.90E+5n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM50157562
PNG
(1,3-bis(3,4-dihydroxyphenyl)prop-2-en-1-one | 3,3'...)
Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)c(O)c2)cc1O
Show InChI InChI=1S/C15H12O5/c16-11(10-3-6-13(18)15(20)8-10)4-1-9-2-5-12(17)14(19)7-9/h1-8,17-20H/b4-1+
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
US Patent
n/an/a 2.14E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170546
PNG
(US9085549, 57 | US9085549, 64)
Show SMILES Oc1ccc(cc1O)-c1nsc(n1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O4S/c17-9-3-1-7(5-11(9)19)13-15-14(21-16-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 1.76E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170560
PNG
(US9085549, 70)
Show SMILES Oc1ccc(cc1O)-c1cnc(o1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C15H11NO5/c17-10-3-1-8(5-12(10)19)14-7-16-15(21-14)9-2-4-11(18)13(20)6-9/h1-7,17-20H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 1.17E+5n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170573
PNG
(US9085549, 97)
Show SMILES Oc1ccc(Cc2cc(O)c(O)cc2O)cc1O
Show InChI InChI=1S/C13H12O5/c14-9-2-1-7(4-11(9)16)3-8-5-12(17)13(18)6-10(8)15/h1-2,4-6,14-18H,3H2
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 5.20E+3n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170558
PNG
(US9085549, 68)
Show SMILES Oc1ccc(cc1O)-c1cn(nn1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H11N3O4/c18-11-3-1-8(5-13(11)20)10-7-17(16-15-10)9-2-4-12(19)14(21)6-9/h1-7,18-21H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 3.40E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170572
PNG
(US9085549, 96)
Show SMILES Oc1ccc(\C=C\C(=O)c2cc(O)c(O)cc2Br)cc1O
Show InChI InChI=1S/C15H11BrO5/c16-10-7-15(21)14(20)6-9(10)11(17)3-1-8-2-4-12(18)13(19)5-8/h1-7,18-21H/b3-1+
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 2.12E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170548
PNG
(US9085549, 52)
Show SMILES Oc1ccc(cc1O)C(=O)Nc1cc(O)c(O)cc1Br
Show InChI InChI=1S/C13H10BrNO5/c14-7-4-11(18)12(19)5-8(7)15-13(20)6-1-2-9(16)10(17)3-6/h1-5,16-19H,(H,15,20)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 3.28E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170543
PNG
(US9085549, 59)
Show SMILES Oc1ccc(cc1O)-c1cc(Br)c(s1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C16H11BrO4S/c17-10-7-15(8-1-3-11(18)13(20)5-8)22-16(10)9-2-4-12(19)14(21)6-9/h1-7,18-21H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.11E+5n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170546
PNG
(US9085549, 57 | US9085549, 64)
Show SMILES Oc1ccc(cc1O)-c1nsc(n1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O4S/c17-9-3-1-7(5-11(9)19)13-15-14(21-16-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 1.02E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170557
PNG
(US9085549, 67)
Show SMILES Oc1ccc(cc1O)-c1nnc(o1)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H10N2O5/c17-9-3-1-7(5-11(9)19)13-15-16-14(21-13)8-2-4-10(18)12(20)6-8/h1-6,17-20H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 3.94E+6n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170574
PNG
(US9085549, 98)
Show SMILES CC(=O)N1N=C(CC1c1ccc(O)c(O)c1)c1ccc(O)c(O)c1 |c:4|
Show InChI InChI=1S/C17H16N2O5/c1-9(20)19-13(11-3-5-15(22)17(24)7-11)8-12(18-19)10-2-4-14(21)16(23)6-10/h2-7,13,21-24H,8H2,1H3
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 7.85E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM170547
PNG
(US9085549, 63)
Show SMILES Oc1ccc(cc1O)-c1ccc(s1)-c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C16H12O5S/c17-10-2-1-8(5-11(10)18)14-3-4-15(22-14)9-6-12(19)16(21)13(20)7-9/h1-7,17-21H
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 1.01E+4n/an/an/an/an/an/a



PROTEOTECH INC

US Patent


Assay Description
The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...

US Patent US9085549 (2015)


BindingDB Entry DOI: 10.7270/Q2WD3Z9K
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%