Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Collagenase 3 (Homo sapiens (Human)) | BDBM50259948![]() (CHEMBL4096462) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | Article PubMed | 0.00800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris-Saclay Curated by ChEMBL | Assay Description Inhibition of human MMP13 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate by spectrophotometric analysis | J Med Chem 60: 403-414 (2017) Article DOI: 10.1021/acs.jmedchem.6b01420 BindingDB Entry DOI: 10.7270/Q24X5B7B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92441![]() (RXP470, 1 | RXP470, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.190 | -55.5 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat à l'Energie Atomique | Assay Description Enzyme assay using matrix metalloproteinases. | J Biol Chem 285: 35900-9 (2010) Article DOI: 10.1074/jbc.M110.139634 BindingDB Entry DOI: 10.7270/Q25X27HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92441![]() (RXP470, 1 | RXP470, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 0.200 | -55.4 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM50265078![]() ((4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | 6.8 | n/a |
CEA Curated by ChEMBL | Assay Description Inhibition of human MMP12 catalytic domain (98 to 266) at pH 6.8 by isothermal titration calorimetry | J Med Chem 56: 1149-59 (2013) Article DOI: 10.1021/jm301574d BindingDB Entry DOI: 10.7270/Q24F1S24 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM50265078![]() ((4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CEA Curated by ChEMBL | Assay Description Binding affinity to human MMP12 catalytic domain (98 to 266) by isothermal titration calorimetry | J Med Chem 56: 1149-59 (2013) Article DOI: 10.1021/jm301574d BindingDB Entry DOI: 10.7270/Q24F1S24 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM50426080![]() (CHEMBL2316257) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CEA Curated by ChEMBL | Assay Description Binding affinity to human MMP12 catalytic domain (98 to 266) by isothermal titration calorimetry | J Med Chem 56: 1149-59 (2013) Article DOI: 10.1021/jm301574d BindingDB Entry DOI: 10.7270/Q24F1S24 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120258![]() (US8691753, 95 bis) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120222![]() (US8691753, 71) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.05 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-2 (Homo sapiens (Human)) | BDBM50259948![]() (CHEMBL4096462) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | Article PubMed | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Paris-Saclay Curated by ChEMBL | Assay Description Inhibition of human MMP10 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate by spectrophotometric analysis | J Med Chem 60: 403-414 (2017) Article DOI: 10.1021/acs.jmedchem.6b01420 BindingDB Entry DOI: 10.7270/Q24X5B7B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120212![]() (US8691753, 61 | US8691753, 72) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120242![]() (US8691753, 91) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 1.84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92443![]() (MMP Inhibitor, 3 | Thiophene derivative, compound ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.90 | -49.8 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120246![]() (US8691753, 95 | US8691753, 96) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | PDB US Patent | 1.92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92443![]() (MMP Inhibitor, 3 | Thiophene derivative, compound ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 1.92 | -49.8 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat à l'Energie Atomique | Assay Description Enzyme assay using matrix metalloproteinases. | J Biol Chem 285: 35900-9 (2010) Article DOI: 10.1074/jbc.M110.139634 BindingDB Entry DOI: 10.7270/Q25X27HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120217![]() (US8691753, 66) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120191![]() (US8691753, 39) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92446![]() (Inhibitor, 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | 2.5 | -49.1 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120252![]() (US8691753, 101) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 2.56 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120243![]() (US8691753, 92) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 2.58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120254![]() (US8691753, 103) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92449![]() (Inhibitor, 19) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 2.90 | -48.7 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92447![]() (Inhibitor, 17) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92448![]() (Inhibitor, 18) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 3.30 | -48.4 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120215![]() (US8691753, 64) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120168![]() (US8691753, 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120219![]() (US8691753, 68) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92445![]() (Inhibitor, 10 | US8691753, 105) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 3.60 | -48.2 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92445![]() (Inhibitor, 10 | US8691753, 105) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM92443![]() (MMP Inhibitor, 3 | Thiophene derivative, compound ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120256![]() (US8691753, 106) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120221![]() (US8691753, 70) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120213![]() (US8691753, 62) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil collagenase (Homo sapiens (Human)) | BDBM92447![]() (Inhibitor, 17) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 5.30 | -47.2 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120173![]() (US8691753, 21) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120250![]() (US8691753, 99) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120216![]() (US8691753, 65) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-2 (Homo sapiens (Human)) | BDBM120222![]() (US8691753, 71) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120220![]() (US8691753, 69) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120241![]() (US8691753, 90) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-2 (Homo sapiens (Human)) | BDBM92441![]() (RXP470, 1 | RXP470, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 8 | -46.2 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat á l'Energie Atomique | Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS. | J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120170![]() (US8691753, 18) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120164![]() (US8691753, 12) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120155![]() (US8691753, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem Similars | PDB US Patent | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Stromelysin-2 (Homo sapiens (Human)) | BDBM92441![]() (RXP470, 1 | RXP470, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 8.30 | -46.1 | n/a | n/a | n/a | n/a | n/a | 6.8 | 25 |
Commissariat à l'Energie Atomique | Assay Description Enzyme assay using matrix metalloproteinases. | J Biol Chem 285: 35900-9 (2010) Article DOI: 10.1074/jbc.M110.139634 BindingDB Entry DOI: 10.7270/Q25X27HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120231![]() (US8691753, 80) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120157![]() (US8691753, 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120218![]() (US8691753, 67) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM120222![]() (US8691753, 71) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 10.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil collagenase (Homo sapiens (Human)) | BDBM120242![]() (US8691753, 91) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 10.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage metalloelastase (Homo sapiens (Human)) | BDBM120225![]() (US8691753, 74) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent | Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ... | US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q | |||||||||||
More data for this Ligand-Target Pair |
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