Compile Data Set for Download or QSAR

Found 2011 hits with Last Name = 'proschak' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009073 (4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation count...				J Med Chem 60: 5235-5266 (2017) Article DOI: 10.1021/acs.jmedchem.6b01287 BindingDB Entry DOI: 10.7270/Q2T43WDQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50227367 (CHEMBL48435) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H31N3O6S/c1-33-19-22(26-18-23(14-15-27(26)33)31-30(35)39-24-8-6-7-9-24)16-20-12-13-21(17-28(20)38-2)29(34)32-40(36,37)25-10-4-3-5-11-25/h3-5,10-15,17-19,24H,6-9,16H2,1-2H3,(H,31,35)(H,32,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation count...				J Med Chem 60: 5235-5266 (2017) Article DOI: 10.1021/acs.jmedchem.6b01287 BindingDB Entry DOI: 10.7270/Q2T43WDQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50462118 (CHEMBL4243296) Show SMILES [#6](-[#7]-1-[#6]-[#6][Si;v4]2([#6]-[#6]-[#6]-c3ccccc23)[#6]-[#6]-1)-c1ccccc1 Show InChI InChI=1S/C20H25NSi/c1-2-7-18(8-3-1)17-21-12-15-22(16-13-21)14-6-10-19-9-4-5-11-20(19)22/h1-5,7-9,11H,6,10,12-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01473 BindingDB Entry DOI: 10.7270/Q2QN6BRZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50518072 (CHEMBL4581645) Show SMILES COc1cc2CCCN(CCCCN3CCN(CC3)c3ccccn3)C(=O)c2cc1OC Show InChI InChI=1S/C25H34N4O3/c1-31-22-18-20-8-7-13-29(25(30)21(20)19-23(22)32-2)12-6-5-11-27-14-16-28(17-15-27)24-9-3-4-10-26-24/h3-4,9-10,18-19H,5-8,11-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Displacement of [3H]-Way100635 from 5HT1A (unknown origin) expressed in CHO cell membranes				J Med Chem 62: 420-444 (2019) Article DOI: 10.1021/acs.jmedchem.8b00760 BindingDB Entry DOI: 10.7270/Q25T3PV2
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50035097 (1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...) Show SMILES C(N1CCC2(CCCc3ccccc23)CC1)c1ccccc1 Show InChI InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01473 BindingDB Entry DOI: 10.7270/Q2QN6BRZ
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50518072 (CHEMBL4581645) Show SMILES COc1cc2CCCN(CCCCN3CCN(CC3)c3ccccn3)C(=O)c2cc1OC Show InChI InChI=1S/C25H34N4O3/c1-31-22-18-20-8-7-13-29(25(30)21(20)19-23(22)32-2)12-6-5-11-27-14-16-28(17-15-27)24-9-3-4-10-26-24/h3-4,9-10,18-19H,5-8,11-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from dopamine D3 receptor (unknown origin) expressed in HEK293 cell membranes				J Med Chem 62: 420-444 (2019) Article DOI: 10.1021/acs.jmedchem.8b00760 BindingDB Entry DOI: 10.7270/Q25T3PV2
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50116538 (3-{[3-(4-Benzyl-phenoxy)-propyl]-methyl-amino}-pro...) Show SMILES CN(CCCOc1ccc(Cc2ccccc2)cc1)CCC(O)=O Show InChI InChI=1S/C20H25NO3/c1-21(14-12-20(22)23)13-5-15-24-19-10-8-18(9-11-19)16-17-6-3-2-4-7-17/h2-4,6-11H,5,12-16H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Non-competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino...				Bioorg Med Chem 24: 5243-5248 (2016) Article DOI: 10.1016/j.bmc.2016.08.047 BindingDB Entry DOI: 10.7270/Q2959KH9
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50518072 (CHEMBL4581645) Show SMILES COc1cc2CCCN(CCCCN3CCN(CC3)c3ccccn3)C(=O)c2cc1OC Show InChI InChI=1S/C25H34N4O3/c1-31-22-18-20-8-7-13-29(25(30)21(20)19-23(22)32-2)12-6-5-11-27-14-16-28(17-15-27)24-9-3-4-10-26-24/h3-4,9-10,18-19H,5-8,11-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Displacement of [3H]-N-methylspiperone from dopamine D4 receptor (unknown origin) expressed in HEK293 cell membranes				J Med Chem 62: 420-444 (2019) Article DOI: 10.1021/acs.jmedchem.8b00760 BindingDB Entry DOI: 10.7270/Q25T3PV2
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304523 (CHEMBL595180 | N4-(2,6-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2c(Cl)cccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-5-7-24(8-6-23)15-9-14(21-16(19)22-15)20-10-11-12(17)3-2-4-13(11)18/h2-4,9H,5-8,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM22566 (5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...) Show SMILES CN1CCN(CC1)C(=O)c1cc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50594427 (CHEMBL5172496) Show SMILES OC(=O)CCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00073 BindingDB Entry DOI: 10.7270/Q2W099ZC
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304524 (CHEMBL594721 | N4-(2-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-4-2-3-5-13(12)17/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50264106 (CHEMBL3818875) Show SMILES CNc1nc(C)nc(N[C@H]2CCC[C@H](C2)C(=O)NCc2ccc(cc2C(F)(F)F)C#N)n1 |r| Show InChI InChI=1S/C21H24F3N7O/c1-12-28-19(26-2)31-20(29-12)30-16-5-3-4-14(9-16)18(32)27-11-15-7-6-13(10-25)8-17(15)21(22,23)24/h6-8,14,16H,3-5,9,11H2,1-2H3,(H,27,32)(H2,26,28,29,30,31)/t14-,16+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00073 BindingDB Entry DOI: 10.7270/Q2W099ZC
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304525 (CHEMBL594731 | N4-(2-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2C)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-5-3-4-6-14(13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50035097 (1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-...) Show SMILES C(N1CCC2(CCCc3ccccc23)CC1)c1ccccc1 Show InChI InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01473 BindingDB Entry DOI: 10.7270/Q2QN6BRZ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304528 (CHEMBL593103 | N4-(4-Fluorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(F)cc2)nc(N)n1 Show InChI InChI=1S/C16H21FN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304526 (CHEMBL594022 | N4-(4-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(Cl)cc2)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304527 (CHEMBL492677 | N4-Benzyl-6-(4-methylpiperazin-1-yl...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2)nc(N)n1 Show InChI InChI=1S/C16H22N6/c1-21-7-9-22(10-8-21)15-11-14(19-16(17)20-15)18-12-13-5-3-2-4-6-13/h2-6,11H,7-10,12H2,1H3,(H3,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50327809 (1-(1-Propionylpiperidin-4-yl)-3-(4-(trifluorometho...) Show SMILES CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C16H20F3N3O3/c1-2-14(23)22-9-7-12(8-10-22)21-15(24)20-11-3-5-13(6-4-11)25-16(17,18)19/h3-6,12H,2,7-10H2,1H3,(H2,20,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	104	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00073 BindingDB Entry DOI: 10.7270/Q2W099ZC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304503 (4-(3,4-Dihydroisoquinolin-2(1H)-yl)-6-(4-methylpip...) Show SMILES CN1CCN(CC1)c1cc(nc(N)n1)N1CCc2ccccc2C1 Show InChI InChI=1S/C18H24N6/c1-22-8-10-23(11-9-22)16-12-17(21-18(19)20-16)24-7-6-14-4-2-3-5-15(14)13-24/h2-5,12H,6-11,13H2,1H3,(H2,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304529 (CHEMBL595215 | N4-(3,4-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(Cl)c(Cl)c2)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-4-6-24(7-5-23)15-9-14(21-16(19)22-15)20-10-11-2-3-12(17)13(18)8-11/h2-3,8-9H,4-7,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50015529 (4-(5-Cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(O)=O Show InChI InChI=1S/C24H26N2O5/c1-26-14-17(11-15-7-8-16(23(27)28)12-22(15)30-2)20-13-18(9-10-21(20)26)25-24(29)31-19-5-3-4-6-19/h7-10,12-14,19H,3-6,11H2,1-2H3,(H,25,29)(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	157	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Displacement of [3H]LTD4 from cysteinyl leukotriene receptor 1 in Hartley guinea pig parenchymal membrane after 30 mins by liquid scintillation count...				J Med Chem 60: 5235-5266 (2017) Article DOI: 10.1021/acs.jmedchem.6b01287 BindingDB Entry DOI: 10.7270/Q2T43WDQ
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50197085 (CHEMBL3921982) Show SMILES CN(C)CCOc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C16H19NO2/c1-17(2)12-13-18-14-8-10-16(11-9-14)19-15-6-4-3-5-7-15/h3-11H,12-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...				Bioorg Med Chem 24: 5243-5248 (2016) Article DOI: 10.1016/j.bmc.2016.08.047 BindingDB Entry DOI: 10.7270/Q2959KH9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304530 (CHEMBL609161 | N4-(4-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(C)cc2)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-3-5-14(6-4-13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304500 (4-((2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(O)cc2)nc(N)n1 Show InChI InChI=1S/C16H22N6O/c1-21-6-8-22(9-7-21)15-10-14(19-16(17)20-15)18-11-12-2-4-13(23)5-3-12/h2-5,10,23H,6-9,11H2,1H3,(H3,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	237	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50502344 (Talinolol) Show SMILES CC(C)(C)NCC(O)COc1ccc(NC(=O)NC2CCCCC2)cc1 Show InChI InChI=1S/C20H33N3O3/c1-20(2,3)21-13-17(24)14-26-18-11-9-16(10-12-18)23-19(25)22-15-7-5-4-6-8-15/h9-12,15,17,21,24H,4-8,13-14H2,1-3H3,(H2,22,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University of Frankfurt Curated by ChEMBL					Assay Description Binding affinity to beta1 adrenergic receptor (unknown origin) by radioligand binding assay				ACS Med Chem Lett 10: 899-903 (2019) Article DOI: 10.1021/acsmedchemlett.9b00075 BindingDB Entry DOI: 10.7270/Q2R214M7
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50462118 (CHEMBL4243296) Show SMILES [#6](-[#7]-1-[#6]-[#6][Si;v4]2([#6]-[#6]-[#6]-c3ccccc23)[#6]-[#6]-1)-c1ccccc1 Show InChI InChI=1S/C20H25NSi/c1-2-7-18(8-3-1)17-21-12-15-22(16-13-21)14-6-10-19-9-4-5-11-20(19)22/h1-5,7-9,11H,6,10,12-17H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	243	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01473 BindingDB Entry DOI: 10.7270/Q2QN6BRZ
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304502 (4-(isoindolin-2-yl)-6-(4-methylpiperazin-1-yl)pyri...) Show SMILES CN1CCN(CC1)c1cc(nc(N)n1)N1Cc2ccccc2C1 Show InChI InChI=1S/C17H22N6/c1-21-6-8-22(9-7-21)15-10-16(20-17(18)19-15)23-11-13-4-2-3-5-14(13)12-23/h2-5,10H,6-9,11-12H2,1H3,(H2,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	248	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304505 (CHEMBL594949 | N4-(3-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2cccc(C)c2)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-4-3-5-14(10-13)12-19-15-11-16(21-17(18)20-15)23-8-6-22(2)7-9-23/h3-5,10-11H,6-9,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304501 (6-(4-Methylpiperazin-1-yl)pyrimidine-2,4-diamine |...) Show SMILES CN1CCN(CC1)c1cc(N)nc(N)n1 Show InChI InChI=1S/C9H16N6/c1-14-2-4-15(5-3-14)8-6-7(10)12-9(11)13-8/h6H,2-5H2,1H3,(H4,10,11,12,13)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304531 (CHEMBL595639 | N4-(3-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2cccc(Cl)c2)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-5-7-23(8-6-22)15-10-14(20-16(18)21-15)19-11-12-3-2-4-13(17)9-12/h2-4,9-10H,5-8,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...				Bioorg Med Chem 24: 5243-5248 (2016) Article DOI: 10.1016/j.bmc.2016.08.047 BindingDB Entry DOI: 10.7270/Q2959KH9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304504 (4-((2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(cc2)C#N)nc(N)n1 Show InChI InChI=1S/C17H21N7/c1-23-6-8-24(9-7-23)16-10-15(21-17(19)22-16)20-12-14-4-2-13(11-18)3-5-14/h2-5,10H,6-9,12H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	341	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50197084 (CHEMBL3883608) Show SMILES Nc1nc(cs1)-c1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C16H14N2S/c17-16-18-15(11-19-16)14-8-6-13(7-9-14)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H2,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe University Frankfurt Curated by ChEMBL					Assay Description Competitive inhibition of human C-terminal his6-tagged/N-terminal T7 gene leader sequence-tagged LTA4H using varying levels of L-arginine-7-amino-4-M...				Bioorg Med Chem 24: 5243-5248 (2016) Article DOI: 10.1016/j.bmc.2016.08.047 BindingDB Entry DOI: 10.7270/Q2959KH9
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304507 (CHEMBL596562 | N-Benzyl-6-(4-methylpiperazin-1-yl)...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2)ncn1 Show InChI InChI=1S/C16H21N5/c1-20-7-9-21(10-8-20)16-11-15(18-13-19-16)17-12-14-5-3-2-4-6-14/h2-6,11,13H,7-10,12H2,1H3,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	417	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304506 (6-(4-Methylpiperazin-1-yl)-N4-(3-nitrobenzyl)pyrim...) Show SMILES CN1CCN(CC1)c1cc(NCc2cccc(c2)[N+]([O-])=O)nc(N)n1 Show InChI InChI=1S/C16H21N7O2/c1-21-5-7-22(8-6-21)15-10-14(19-16(17)20-15)18-11-12-3-2-4-13(9-12)23(24)25/h2-4,9-10H,5-8,11H2,1H3,(H3,17,18,19,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	538	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304509 (CHEMBL608717 | N4-(4-Methoxybenzyl)-6-(4-methylpip...) Show SMILES COc1ccc(CNc2cc(nc(N)n2)N2CCN(C)CC2)cc1 Show InChI InChI=1S/C17H24N6O/c1-22-7-9-23(10-8-22)16-11-15(20-17(18)21-16)19-12-13-3-5-14(24-2)6-4-13/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	542	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50594426 (CHEMBL5177249) Show SMILES FC(F)(F)c1cc(NS(=O)(=O)C2CC2)ccc1CNC(=O)c1ccc2[nH]ccc2c1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00073 BindingDB Entry DOI: 10.7270/Q2W099ZC
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304508 (CHEMBL593551 | N4-(Biphenyl-4-ylmethyl)-6-(4-methy...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(cc2)-c2ccccc2)nc(N)n1 Show InChI InChI=1S/C22H26N6/c1-27-11-13-28(14-12-27)21-15-20(25-22(23)26-21)24-16-17-7-9-19(10-8-17)18-5-3-2-4-6-18/h2-10,15H,11-14,16H2,1H3,(H3,23,24,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	716	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50502344 (Talinolol) Show SMILES CC(C)(C)NCC(O)COc1ccc(NC(=O)NC2CCCCC2)cc1 Show InChI InChI=1S/C20H33N3O3/c1-20(2,3)21-13-17(24)14-26-18-11-9-16(10-12-18)23-19(25)22-15-7-5-4-6-8-15/h9-12,15,17,21,24H,4-8,13-14H2,1-3H3,(H2,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University of Frankfurt Curated by ChEMBL					Assay Description Binding affinity to beta2 adrenergic receptor (unknown origin) by radioligand binding assay				ACS Med Chem Lett 10: 899-903 (2019) Article DOI: 10.1021/acsmedchemlett.9b00075 BindingDB Entry DOI: 10.7270/Q2R214M7
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304523 (CHEMBL595180 | N4-(2,6-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2c(Cl)cccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-5-7-24(8-6-23)15-9-14(21-16(19)22-15)20-10-11-12(17)3-2-4-13(11)18/h2-4,9H,5-8,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304525 (CHEMBL594731 | N4-(2-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2C)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-5-3-4-6-14(13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304528 (CHEMBL593103 | N4-(4-Fluorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(F)cc2)nc(N)n1 Show InChI InChI=1S/C16H21FN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50304524 (CHEMBL594721 | N4-(2-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-4-2-3-5-13(12)17/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]tiotidine from GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304523 (CHEMBL595180 | N4-(2,6-Dichlorobenzyl)-6-(4-methyl...) Show SMILES CN1CCN(CC1)c1cc(NCc2c(Cl)cccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H20Cl2N6/c1-23-5-7-24(8-6-23)15-9-14(21-16(19)22-15)20-10-11-12(17)3-2-4-13(11)18/h2-4,9H,5-8,10H2,1H3,(H3,19,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304528 (CHEMBL593103 | N4-(4-Fluorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(F)cc2)nc(N)n1 Show InChI InChI=1S/C16H21FN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-2-4-13(17)5-3-12/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304525 (CHEMBL594731 | N4-(2-Methylbenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2C)nc(N)n1 Show InChI InChI=1S/C17H24N6/c1-13-5-3-4-6-14(13)12-19-15-11-16(21-17(18)20-15)23-9-7-22(2)8-10-23/h3-6,11H,7-10,12H2,1-2H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50304524 (CHEMBL594721 | N4-(2-Chlorobenzyl)-6-(4-methylpipe...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccccc2Cl)nc(N)n1 Show InChI InChI=1S/C16H21ClN6/c1-22-6-8-23(9-7-22)15-10-14(20-16(18)21-15)19-11-12-4-2-3-5-13(12)17/h2-5,10H,6-9,11H2,1H3,(H3,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in Sf9 cells co-expressing RGS4				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304519 (6-(4-Methylpiperazin-1-yl)-N4-(4-(trifluoromethyl)...) Show SMILES CN1CCN(CC1)c1cc(NCc2ccc(cc2)C(F)(F)F)nc(N)n1 Show InChI InChI=1S/C17H21F3N6/c1-25-6-8-26(9-7-25)15-10-14(23-16(21)24-15)22-11-12-2-4-13(5-3-12)17(18,19)20/h2-5,10H,6-9,11H2,1H3,(H3,21,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50304521 (CHEMBL610626 | N4-(4-Isopropylbenzyl)-6-(4-methylp...) Show SMILES CC(C)c1ccc(CNc2cc(nc(N)n2)N2CCN(C)CC2)cc1 Show InChI InChI=1S/C19H28N6/c1-14(2)16-6-4-15(5-7-16)13-21-17-12-18(23-19(20)22-17)25-10-8-24(3)9-11-25/h4-7,12,14H,8-11,13H2,1-3H3,(H3,20,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2				Bioorg Med Chem 17: 7186-96 (2009) Article DOI: 10.1016/j.bmc.2009.08.059 BindingDB Entry DOI: 10.7270/Q2416X4F
					More data for this Ligand-Target Pair

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