Compile Data Set for Download or QSAR

Found 949 hits with Last Name = 'eldemenky' and Initial = 'em'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353455 (CHEMBL1830049) Show SMILES O=c1cc(OCc2ccccc2)ccn1-c1ccc2N(CCc2c1)C1CNC1 Show InChI InChI=1S/C23H23N3O2/c27-23-13-21(28-16-17-4-2-1-3-5-17)9-11-26(23)19-6-7-22-18(12-19)8-10-25(22)20-14-24-15-20/h1-7,9,11-13,20,24H,8,10,14-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353456 (CHEMBL1830050) Show SMILES CN1CC(C1)N1CCc2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C24H25N3O2/c1-25-15-21(16-25)26-11-9-19-13-20(7-8-23(19)26)27-12-10-22(14-24(27)28)29-17-18-5-3-2-4-6-18/h2-8,10,12-14,21H,9,11,15-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353453 (CHEMBL1830047) Show SMILES FCCN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C25H24FN3O2/c26-9-11-28-15-19(16-28)23-14-27-24-12-20(6-7-22(23)24)29-10-8-21(13-25(29)30)31-17-18-4-2-1-3-5-18/h1-8,10,12-14,19,27H,9,11,15-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353458 (CHEMBL1830052) Show SMILES CN1CC(C1)N1CCc2cc(ccc12)-n1ccc(cc1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H22ClN3O/c1-25-14-21(15-25)26-10-9-18-12-20(6-7-22(18)26)27-11-8-17(13-23(27)28)16-2-4-19(24)5-3-16/h2-8,11-13,21H,9-10,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353457 (CHEMBL1830051) Show SMILES FCCN1CC(C1)N1CCc2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C25H26FN3O2/c26-10-13-27-16-22(17-27)28-11-8-20-14-21(6-7-24(20)28)29-12-9-23(15-25(29)30)31-18-19-4-2-1-3-5-19/h1-7,9,12,14-15,22H,8,10-11,13,16-18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353452 (CHEMBL1830046) Show SMILES COCCN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C26H27N3O3/c1-31-12-11-28-16-20(17-28)24-15-27-25-13-21(7-8-23(24)25)29-10-9-22(14-26(29)30)32-18-19-5-3-2-4-6-19/h2-10,13-15,20,27H,11-12,16-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353459 (CHEMBL1830053) Show SMILES FCCN1CC(C1)N1CCc2cc(ccc12)-n1ccc(cc1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClFN3O/c25-20-3-1-17(2-4-20)18-7-11-29(24(30)14-18)21-5-6-23-19(13-21)8-10-28(23)22-15-27(16-22)12-9-26/h1-7,11,13-14,22H,8-10,12,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353449 (CHEMBL1830043) Show SMILES CN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2F)cc1=O Show InChI InChI=1S/C24H22FN3O2/c1-27-13-17(14-27)21-12-26-23-10-18(6-7-20(21)23)28-9-8-19(11-24(28)29)30-15-16-4-2-3-5-22(16)25/h2-12,17,26H,13-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353450 (CHEMBL1830044) Show SMILES CN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(cc1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H20ClN3O/c1-26-13-17(14-26)21-12-25-22-11-19(6-7-20(21)22)27-9-8-16(10-23(27)28)15-2-4-18(24)5-3-15/h2-12,17,25H,13-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353454 (CHEMBL1830048) Show SMILES Cn1cc(C2CN(CCF)C2)c2ccc(cc12)-n1ccc(cc1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C25H23F2N3O/c1-28-16-23(19-14-29(15-19)11-9-26)22-7-6-21(13-24(22)28)30-10-8-18(12-25(30)31)17-2-4-20(27)5-3-17/h2-8,10,12-13,16,19H,9,11,14-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353448 (CHEMBL1830042) Show SMILES CN1CC(C1)c1c[nH]c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C24H23N3O2/c1-26-14-18(15-26)22-13-25-23-11-19(7-8-21(22)23)27-10-9-20(12-24(27)28)29-16-17-5-3-2-4-6-17/h2-13,18,25H,14-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50353451 (CHEMBL1830045) Show SMILES CN1CC(C1)c1cn(C)c2cc(ccc12)-n1ccc(OCc2ccccc2)cc1=O Show InChI InChI=1S/C25H25N3O2/c1-26-14-19(15-26)23-16-27(2)24-12-20(8-9-22(23)24)28-11-10-21(13-25(28)29)30-17-18-6-4-3-5-7-18/h3-13,16,19H,14-15,17H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-S36057 from rat MCH1 receptor				Bioorg Med Chem Lett 21: 5310-4 (2011) Article DOI: 10.1016/j.bmcl.2011.07.020 BindingDB Entry DOI: 10.7270/Q2DJ5G0J
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173706 (US9102591, (+)2-chloro-N-[3-[1-(trifluoromethyl)cy...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1ccccc1Cl)CC1(CC1)C(F)(F)F Show InChI InChI=1S/C20H17ClF6N2O/c21-15-4-2-1-3-14(15)17(30)29-11-13(9-18(7-8-18)20(25,26)27)12-5-6-16(28-10-12)19(22,23)24/h1-6,10,13H,7-9,11H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173706 (US9102591, (+)2-chloro-N-[3-[1-(trifluoromethyl)cy...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1ccccc1Cl)CC1(CC1)C(F)(F)F Show InChI InChI=1S/C20H17ClF6N2O/c21-15-4-2-1-3-14(15)17(30)29-11-13(9-18(7-8-18)20(25,26)27)12-5-6-16(28-10-12)19(22,23)24/h1-6,10,13H,7-9,11H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173649 (US9102591, 2,3-dichloro-N-[[4,4-difluoro-1-(6-fluo...) Show SMILES Fc1ccc(cn1)C1(CNC(=O)c2cccc(Cl)c2Cl)CCC(F)(F)CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-14-3-1-2-13(16(14)21)17(27)26-11-18(6-8-19(23,24)9-7-18)12-4-5-15(22)25-10-12/h1-5,10H,6-9,11H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173649 (US9102591, 2,3-dichloro-N-[[4,4-difluoro-1-(6-fluo...) Show SMILES Fc1ccc(cn1)C1(CNC(=O)c2cccc(Cl)c2Cl)CCC(F)(F)CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-14-3-1-2-13(16(14)21)17(27)26-11-18(6-8-19(23,24)9-7-18)12-4-5-15(22)25-10-12/h1-5,10H,6-9,11H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173649 (US9102591, 2,3-dichloro-N-[[4,4-difluoro-1-(6-fluo...) Show SMILES Fc1ccc(cn1)C1(CNC(=O)c2cccc(Cl)c2Cl)CCC(F)(F)CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-14-3-1-2-13(16(14)21)17(27)26-11-18(6-8-19(23,24)9-7-18)12-4-5-15(22)25-10-12/h1-5,10H,6-9,11H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173675 (US9102591, (+)2,3-dichloro-N-[3-cyclopropyl-2-[6-(...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)CC1CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-15-3-1-2-14(17(15)21)18(27)26-10-13(8-11-4-5-11)12-6-7-16(25-9-12)19(22,23)24/h1-3,6-7,9,11,13H,4-5,8,10H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173675 (US9102591, (+)2,3-dichloro-N-[3-cyclopropyl-2-[6-(...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)CC1CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-15-3-1-2-14(17(15)21)18(27)26-10-13(8-11-4-5-11)12-6-7-16(25-9-12)19(22,23)24/h1-3,6-7,9,11,13H,4-5,8,10H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242031 (US9415055, 2,3-Dichloro-N-[2-(4,4-difluoro-piperid...) Show SMILES Fc1ccc(cc1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCC(F)(F)CC1 Show InChI InChI=1S/C20H19Cl2F3N2O/c21-16-3-1-2-15(18(16)22)19(28)26-12-17(13-4-6-14(23)7-5-13)27-10-8-20(24,25)9-11-27/h1-7,17H,8-12H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...				US Patent US9593105 (2017) BindingDB Entry DOI: 10.7270/Q2R49STH
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242031 (US9415055, 2,3-Dichloro-N-[2-(4,4-difluoro-piperid...) Show SMILES Fc1ccc(cc1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCC(F)(F)CC1 Show InChI InChI=1S/C20H19Cl2F3N2O/c21-16-3-1-2-15(18(16)22)19(28)26-12-17(13-4-6-14(23)7-5-13)27-10-8-20(24,25)9-11-27/h1-7,17H,8-12H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.330	n/a	n/a	n/a	n/a	7.4	37
H. Lundbeck A/S US Patent					Assay Description Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...				US Patent US9415055 (2016) BindingDB Entry DOI: 10.7270/Q2NC604C
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242026 (US9415055, 2-Chloro-N-[(S)-2-(4-chloro-phenyl)-2-m...) Show SMILES Cc1cccc(C(=O)NC[C@@H](N2CCOCC2)c2ccc(Cl)cc2)c1Cl Show InChI InChI=1S/C20H22Cl2N2O2/c1-14-3-2-4-17(19(14)22)20(25)23-13-18(24-9-11-26-12-10-24)15-5-7-16(21)8-6-15/h2-8,18H,9-13H2,1H3,(H,23,25)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	7.4	37
H. Lundbeck A/S US Patent					Assay Description Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...				US Patent US9415055 (2016) BindingDB Entry DOI: 10.7270/Q2NC604C
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242026 (US9415055, 2-Chloro-N-[(S)-2-(4-chloro-phenyl)-2-m...) Show SMILES Cc1cccc(C(=O)NC[C@@H](N2CCOCC2)c2ccc(Cl)cc2)c1Cl Show InChI InChI=1S/C20H22Cl2N2O2/c1-14-3-2-4-17(19(14)22)20(25)23-13-18(24-9-11-26-12-10-24)15-5-7-16(21)8-6-15/h2-8,18H,9-13H2,1H3,(H,23,25)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...				US Patent US9593105 (2017) BindingDB Entry DOI: 10.7270/Q2R49STH
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173682 (US9102591, 2-chloro-N-((4,4-difluoro-1-(6-(trifluo...) Show SMILES Cc1cccc(C(=O)NCC2(CCC(F)(F)CC2)c2ccc(nc2)C(F)(F)F)c1Cl Show InChI InChI=1S/C21H20ClF5N2O/c1-13-3-2-4-15(17(13)22)18(30)29-12-19(7-9-20(23,24)10-8-19)14-5-6-16(28-11-14)21(25,26)27/h2-6,11H,7-10,12H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173682 (US9102591, 2-chloro-N-((4,4-difluoro-1-(6-(trifluo...) Show SMILES Cc1cccc(C(=O)NCC2(CCC(F)(F)CC2)c2ccc(nc2)C(F)(F)F)c1Cl Show InChI InChI=1S/C21H20ClF5N2O/c1-13-3-2-4-15(17(13)22)18(30)29-12-19(7-9-20(23,24)10-8-19)14-5-6-16(28-11-14)21(25,26)27/h2-6,11H,7-10,12H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.540	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173675 (US9102591, (+)2,3-dichloro-N-[3-cyclopropyl-2-[6-(...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)CC1CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-15-3-1-2-14(17(15)21)18(27)26-10-13(8-11-4-5-11)12-6-7-16(25-9-12)19(22,23)24/h1-3,6-7,9,11,13H,4-5,8,10H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173675 (US9102591, (+)2,3-dichloro-N-[3-cyclopropyl-2-[6-(...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)CC1CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-15-3-1-2-14(17(15)21)18(27)26-10-13(8-11-4-5-11)12-6-7-16(25-9-12)19(22,23)24/h1-3,6-7,9,11,13H,4-5,8,10H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242040 (US9415055, 2,3-dichloro-N-[2-(4,4-difluoro-1-piper...) Show SMILES COc1ccc(cc1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCC(F)(F)CC1 Show InChI InChI=1S/C21H22Cl2F2N2O2/c1-29-15-7-5-14(6-8-15)18(27-11-9-21(24,25)10-12-27)13-26-20(28)16-3-2-4-17(22)19(16)23/h2-8,18H,9-13H2,1H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.4	37
H. Lundbeck A/S US Patent					Assay Description Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...				US Patent US9415055 (2016) BindingDB Entry DOI: 10.7270/Q2NC604C
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242222 (US9415055, 2,3-Dichloro-N-[2-(4-chloro-phenyl)-2-m...) Show SMILES Clc1ccc(cc1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCOCC1 Show InChI InChI=1S/C19H19Cl3N2O2/c20-14-6-4-13(5-7-14)17(24-8-10-26-11-9-24)12-23-19(25)15-2-1-3-16(21)18(15)22/h1-7,17H,8-12H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...				US Patent US9593105 (2017) BindingDB Entry DOI: 10.7270/Q2R49STH
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242222 (US9415055, 2,3-Dichloro-N-[2-(4-chloro-phenyl)-2-m...) Show SMILES Clc1ccc(cc1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCOCC1 Show InChI InChI=1S/C19H19Cl3N2O2/c20-14-6-4-13(5-7-14)17(24-8-10-26-11-9-24)12-23-19(25)15-2-1-3-16(21)18(15)22/h1-7,17H,8-12H2,(H,23,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.4	37
H. Lundbeck A/S US Patent					Assay Description Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...				US Patent US9415055 (2016) BindingDB Entry DOI: 10.7270/Q2NC604C
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242040 (US9415055, 2,3-dichloro-N-[2-(4,4-difluoro-1-piper...) Show SMILES COc1ccc(cc1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCC(F)(F)CC1 Show InChI InChI=1S/C21H22Cl2F2N2O2/c1-29-15-7-5-14(6-8-15)18(27-11-9-21(24,25)10-12-27)13-26-20(28)16-3-2-4-17(22)19(16)23/h2-8,18H,9-13H2,1H3,(H,26,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...				US Patent US9593105 (2017) BindingDB Entry DOI: 10.7270/Q2R49STH
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242021 (US9415055, 2,3-Dichloro-N-[(S)-2-(4-chloro-phenyl)...) Show SMILES Clc1ccc(cc1)[C@@H](CNC(=O)c1cccc(Cl)c1Cl)N1CCOCC1 |r| Show InChI InChI=1S/C19H19Cl3N2O2/c20-14-6-4-13(5-7-14)17(24-8-10-26-11-9-24)12-23-19(25)15-2-1-3-16(21)18(15)22/h1-7,17H,8-12H2,(H,23,25)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.620	n/a	n/a	n/a	n/a	7.4	37
H. Lundbeck A/S US Patent					Assay Description Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...				US Patent US9415055 (2016) BindingDB Entry DOI: 10.7270/Q2NC604C
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242080 (US9415055, (+)2-chloro-N-[2-(4,4-difluoro-1-piperi...) Show SMILES Fc1cccc(Cl)c1C(=O)NCC(N1CCC(F)(F)CC1)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C20H18ClF6N3O/c21-13-2-1-3-14(22)17(13)18(31)29-11-15(30-8-6-19(23,24)7-9-30)12-4-5-16(28-10-12)20(25,26)27/h1-5,10,15H,6-9,11H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.620	n/a	n/a	n/a	n/a	7.4	37
H. Lundbeck A/S US Patent					Assay Description Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...				US Patent US9415055 (2016) BindingDB Entry DOI: 10.7270/Q2NC604C
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242080 (US9415055, (+)2-chloro-N-[2-(4,4-difluoro-1-piperi...) Show SMILES Fc1cccc(Cl)c1C(=O)NCC(N1CCC(F)(F)CC1)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C20H18ClF6N3O/c21-13-2-1-3-14(22)17(13)18(31)29-11-15(30-8-6-19(23,24)7-9-30)12-4-5-16(28-10-12)20(25,26)27/h1-5,10,15H,6-9,11H2,(H,29,31)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...				US Patent US9593105 (2017) BindingDB Entry DOI: 10.7270/Q2R49STH
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242021 (US9415055, 2,3-Dichloro-N-[(S)-2-(4-chloro-phenyl)...) Show SMILES Clc1ccc(cc1)[C@@H](CNC(=O)c1cccc(Cl)c1Cl)N1CCOCC1 |r| Show InChI InChI=1S/C19H19Cl3N2O2/c20-14-6-4-13(5-7-14)17(24-8-10-26-11-9-24)12-23-19(25)15-2-1-3-16(21)18(15)22/h1-7,17H,8-12H2,(H,23,25)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...				US Patent US9593105 (2017) BindingDB Entry DOI: 10.7270/Q2R49STH
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242069 (US9415055, 2,3-dichloro-N-[2-(4,4-difluoro-1-piper...) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCC(F)(F)CC1 Show InChI InChI=1S/C19H17Cl2F5N4O/c20-13-3-1-2-12(15(13)21)16(31)27-10-14(30-6-4-18(22,23)5-7-30)11-8-28-17(29-9-11)19(24,25)26/h1-3,8-9,14H,4-7,10H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...				US Patent US9593105 (2017) BindingDB Entry DOI: 10.7270/Q2R49STH
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM242069 (US9415055, 2,3-dichloro-N-[2-(4,4-difluoro-1-piper...) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)N1CCC(F)(F)CC1 Show InChI InChI=1S/C19H17Cl2F5N4O/c20-13-3-1-2-12(15(13)21)16(31)27-10-14(30-6-4-18(22,23)5-7-30)11-8-28-17(29-9-11)19(24,25)26/h1-3,8-9,14H,4-7,10H2,(H,27,31)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.650	n/a	n/a	n/a	n/a	7.4	37
H. Lundbeck A/S US Patent					Assay Description Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...				US Patent US9415055 (2016) BindingDB Entry DOI: 10.7270/Q2NC604C
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173739 (US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1c(Cl)cccc1Cl)CC1CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-14-2-1-3-15(21)17(14)18(27)26-10-13(8-11-4-5-11)12-6-7-16(25-9-12)19(22,23)24/h1-3,6-7,9,11,13H,4-5,8,10H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173681 (US9102591, 3-bromo-N-((4,4-difluoro-1-(6-(trifluor...) Show SMILES Cc1c(Br)cccc1C(=O)NCC1(CCC(F)(F)CC1)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C21H20BrF5N2O/c1-13-15(3-2-4-16(13)22)18(30)29-12-19(7-9-20(23,24)10-8-19)14-5-6-17(28-11-14)21(25,26)27/h2-6,11H,7-10,12H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173739 (US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[6-(...) Show SMILES FC(F)(F)c1ccc(cn1)C(CNC(=O)c1c(Cl)cccc1Cl)CC1CC1 Show InChI InChI=1S/C19H17Cl2F3N2O/c20-14-2-1-3-15(21)17(14)18(27)26-10-13(8-11-4-5-11)12-6-7-16(25-9-12)19(22,23)24/h1-3,6-7,9,11,13H,4-5,8,10H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173681 (US9102591, 3-bromo-N-((4,4-difluoro-1-(6-(trifluor...) Show SMILES Cc1c(Br)cccc1C(=O)NCC1(CCC(F)(F)CC1)c1ccc(nc1)C(F)(F)F Show InChI InChI=1S/C21H20BrF5N2O/c1-13-15(3-2-4-16(13)22)18(30)29-12-19(7-9-20(23,24)10-8-19)14-5-6-17(28-11-14)21(25,26)27/h2-6,11H,7-10,12H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173651 (US9102591, 2-chloro-N-[[4,4-difluoro-1-(6-fluoro-3...) Show SMILES Cc1ccc(Cl)c(c1)C(=O)NCC1(CCC(F)(F)CC1)c1ccc(F)nc1 Show InChI InChI=1S/C20H20ClF3N2O/c1-13-2-4-16(21)15(10-13)18(27)26-12-19(6-8-20(23,24)9-7-19)14-3-5-17(22)25-11-14/h2-5,10-11H,6-9,12H2,1H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173651 (US9102591, 2-chloro-N-[[4,4-difluoro-1-(6-fluoro-3...) Show SMILES Cc1ccc(Cl)c(c1)C(=O)NCC1(CCC(F)(F)CC1)c1ccc(F)nc1 Show InChI InChI=1S/C20H20ClF3N2O/c1-13-2-4-16(21)15(10-13)18(27)26-12-19(6-8-20(23,24)9-7-19)14-3-5-17(22)25-11-14/h2-5,10-11H,6-9,12H2,1H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.760	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173694 (US9102591, 2,3-dichloro-N-[2-(6-cyclopropyl-3-pyri...) Show SMILES FC(F)C1(CC(CNC(=O)c2cccc(Cl)c2Cl)c2ccc(nc2)C2CC2)CC1 Show InChI InChI=1S/C22H22Cl2F2N2O/c23-17-3-1-2-16(19(17)24)20(29)28-12-15(10-22(8-9-22)21(25)26)14-6-7-18(27-11-14)13-4-5-13/h1-3,6-7,11,13,15,21H,4-5,8-10,12H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.760	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173694 (US9102591, 2,3-dichloro-N-[2-(6-cyclopropyl-3-pyri...) Show SMILES FC(F)C1(CC(CNC(=O)c2cccc(Cl)c2Cl)c2ccc(nc2)C2CC2)CC1 Show InChI InChI=1S/C22H22Cl2F2N2O/c23-17-3-1-2-16(19(17)24)20(29)28-12-15(10-22(8-9-22)21(25)26)14-6-7-18(27-11-14)13-4-5-13/h1-3,6-7,11,13,15,21H,4-5,8-10,12H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173753 (US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[2-(...) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)cccc1Cl)CC1CC1 Show InChI InChI=1S/C18H16Cl2F3N3O/c19-13-2-1-3-14(20)15(13)16(27)24-7-11(6-10-4-5-10)12-8-25-17(26-9-12)18(21,22)23/h1-3,8-11H,4-7H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.820	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173753 (US9102591, (+)2,6-dichloro-N-[3-cyclopropyl-2-[2-(...) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1c(Cl)cccc1Cl)CC1CC1 Show InChI InChI=1S/C18H16Cl2F3N3O/c19-13-2-1-3-14(20)15(13)16(27)24-7-11(6-10-4-5-10)12-8-25-17(26-9-12)18(21,22)23/h1-3,8-11H,4-7H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173661 (US9102591, 2-chloro-N-((4,4-difluoro-1-(6-fluoropy...) Show SMILES COc1ccc(Cl)c(c1)C(=O)NCC1(CCC(F)(F)CC1)c1ccc(F)nc1 Show InChI InChI=1S/C20H20ClF3N2O2/c1-28-14-3-4-16(21)15(10-14)18(27)26-12-19(6-8-20(23,24)9-7-19)13-2-5-17(22)25-11-13/h2-5,10-11H,6-9,12H2,1H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.830	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173661 (US9102591, 2-chloro-N-((4,4-difluoro-1-(6-fluoropy...) Show SMILES COc1ccc(Cl)c(c1)C(=O)NCC1(CCC(F)(F)CC1)c1ccc(F)nc1 Show InChI InChI=1S/C20H20ClF3N2O2/c1-28-14-3-4-16(21)15(10-14)18(27)26-12-19(6-8-20(23,24)9-7-19)13-2-5-17(22)25-11-13/h2-5,10-11H,6-9,12H2,1H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.830	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173710 (US9102591, (+)2,3-dichloro-N-[3-cyclopropyl-2-[2-(...) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1cccc(Cl)c1Cl)CC1CC1 Show InChI InChI=1S/C18H16Cl2F3N3O/c19-14-3-1-2-13(15(14)20)16(27)24-7-11(6-10-4-5-10)12-8-25-17(26-9-12)18(21,22)23/h1-3,8-11H,4-7H2,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.860	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair

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