Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Substance-K receptor (Homo sapiens (Human)) | BDBM50256882 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human neurokinin NK2 receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Homo sapiens (Human)) | BDBM50256882 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibition of human histamine H2 receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50065115 (3-chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087670 (Biphenyl-2-carboxylic acid {3-chloro-4-[3-(4-methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50244213 (5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256836 (7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087664 (Biphenyl-2-carboxylic acid {3-chloro-4-[3-(4-dimet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087675 (Biphenyl-2-carboxylic acid [4-(3-[1,4']bipiperidin...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50315277 (5-((4-(2-(4-tert-butylphenyl)imidazo[1,2-a]pyridin...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087674 (Biphenyl-2-carboxylic acid [3-chloro-4-(3-{[(2-dim...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256834 (7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087667 (10-{4-[(Biphenyl-2-carbonyl)-amino]-2-chloro-benzo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50244213 (5-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GnRH receptor expressed in HEK293 cells assessed as reduction in (D-Trp6)-GnRH-stimulated IP production by w... | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50315276 (5-((4-(2-(4-tert-butylphenyl)imidazo[1,2-a]pyridin...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50244211 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50315277 (5-((4-(2-(4-tert-butylphenyl)imidazo[1,2-a]pyridin...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GNRH receptor assessed as inhibition of D-Trp6-GNRH-induced IP accumulation after 1 hr by rapid filtration a... | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087672 (Biphenyl-2-carboxylic acid [4-(3-dimethylaminometh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256835 (7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Rattus norvegicus) | BDBM50315277 (5-((4-(2-(4-tert-butylphenyl)imidazo[1,2-a]pyridin...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from rat recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50258205 (2-(4-tert-butylphenyl)-4-(4-((1-ethyl-5-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50315275 (2-(4-tert-butylphenyl)-8-(4-((1-ethyl-5-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50258205 (2-(4-tert-butylphenyl)-4-(4-((1-ethyl-5-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087673 (Biphenyl-2-carboxylic acid {3-methoxy-4-[3-(4-meth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256834 (7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reduction | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087666 (Biphenyl-2-carboxylic acid [3-chloro-4-(3-dimethyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50258018 (2-(4-tert-butylphenyl)-4-(4-((2-methyl-1H-imidazol...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50257669 (2-(4-tert-butylphenyl)-4-(4-((1,2-diethyl-5-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087665 (Biphenyl-2-carboxylic acid {3-chloro-4-[3-(4-dimet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 8.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50244211 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reduction | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256836 (7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reduction | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50315271 (2-(4-tert-butylphenyl)-8-(4-((2-ethyl-5-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50261251 (2-(4-tert-butylphenyl)-4-(4-((2-ethyl-4-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50257516 (2-(4-tert-butylphenyl)-4-(4-((1-ethyl-2-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50257513 (2-(4-tert-butylphenyl)-4-(4-((1,2-dimethyl-1H-imid...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50257668 (2-(4-tert-butylphenyl)-4-(4-((1,2-diethyl-1H-imida...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087669 (Biphenyl-2-carboxylic acid {3-chloro-4-[3-(4-methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256882 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50258245 (2-(4-tert-butylphenyl)-4-(4-((5-methyl-1-propyl-1H...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256882 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Rattus norvegicus) | BDBM50315275 (2-(4-tert-butylphenyl)-8-(4-((1-ethyl-5-methyl-1H-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [125I]D-Trp6-GnRH from rat recombinant GNRH receptor by scintillation counting | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50257669 (2-(4-tert-butylphenyl)-4-(4-((1,2-diethyl-5-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GnRH receptor expressed in HEK293 cells assessed as reduction in (D-Trp6)-GnRH-stimulated IP production by w... | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087668 (10-[2-Chloro-4-(5-fluoro-2-methyl-benzoylamino)-be...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50258205 (2-(4-tert-butylphenyl)-4-(4-((1-ethyl-5-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GnRH receptor expressed in HEK293 cells assessed as reduction in (D-Trp6)-GnRH-stimulated IP production by w... | Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256835 (7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reduction | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50258205 (2-(4-tert-butylphenyl)-4-(4-((1-ethyl-5-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GNRH receptor assessed as inhibition of D-Trp6-GNRH-induced IP accumulation after 1 hr by rapid filtration a... | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM50087671 (Biphenyl-2-carboxylic acid [4-(3-dimethylaminometh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Displacement of [3H]-AVP from human vasopressin V2-receptor expressed in murine fibroblast cell (LV2) membranes | Bioorg Med Chem Lett 10: 783-6 (2000) BindingDB Entry DOI: 10.7270/Q24M93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256881 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human GnRH receptor assessed as inhibition of [D-Trp6]-GnRH-stimulated [3H]IP reduction | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50256881 (6-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [D-Trp6]-GnRH from human recombinant GnRH receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Rattus norvegicus) | BDBM50256834 (7-((4-(2-(4-tert-butylphenyl)-1H-benzo[d]imidazol-...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Displacement of [D-Trp6]-GnRH from rat recombinant GnRH receptor | J Med Chem 52: 2148-52 (2009) Article DOI: 10.1021/jm801572m BindingDB Entry DOI: 10.7270/Q2ZC82RT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50261251 (2-(4-tert-butylphenyl)-4-(4-((2-ethyl-4-methyl-1H-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GNRH receptor assessed as inhibition of D-Trp6-GNRH-induced IP accumulation after 1 hr by rapid filtration a... | Bioorg Med Chem Lett 20: 2512-5 (2010) Article DOI: 10.1016/j.bmcl.2010.02.099 BindingDB Entry DOI: 10.7270/Q2W0962G | |||||||||||
More data for this Ligand-Target Pair |
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