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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209482 ((3S)-3-(5-chloro-2-hydroxy-3-methylphenyl)-3-(2-(3...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209479 ((beta1S)-3-bromo-5-chloro-b-[[[[3-[(5-fluoro-1,4,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209459 ((3R)-3-(2-(3-amino-5-(5-hydroxy-1,4,5,6-tetrahydro...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209471 ((3S)-3-(5-bromo-3-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209446 ((3S)-3-(3,5-dichloro-2-hydroxyphenyl)-3-(2-(3-(5-h...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209461 ((3S)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209441 ((3S)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029613 (1-Methoxy-4-(2-(4-(methanesulfonyl)phenyl)cyclopen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209456 ((3S)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209450 ((beta1R)-3-bromo-5-chloro-b-[[[[3-[(5-fluoro-1,4,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209475 ((3R)-3-(3,5-dichloro-2-hydroxyphenyl)-3-(2-(3-(5-h...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209428 ((3R)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209463 ((beta1S)-3,5-dichloro-b-[[[[3-[(5-hydroxy-1,4,5,6-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209486 ((S)-3-(3,5-dichloro-2-hydroxyphenyl)-3-(2-(3-hydro...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209477 ((beta1R)-3-bromo-5-chloro-b-[[[[3-[(5-fluoro-1,4,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209481 ((3R)-3-(5-chloro-2-hydroxy-3-iodophenyl)-3-(2-(3-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209483 ((beta1R)-3-bromo-5-chloro-b-[[[[3-[(5-fluoro-1,4,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209425 ((3R)-3-(5-bromo-3-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209431 ((3R)-3-(3,5-dichloro-2-hydroxyphenyl)-3-(2-(3-(5-f...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209439 ((3R)-3-(5-chloro-2-hydroxy-3-iodophenyl)-3-(2-(3-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209460 ((3R)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209488 ((3S)-3-(2-hydroxy-3,5-dimethylphenyl)-3-(2-(3-hydr...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209448 ((3R)-3-(3,5-dichloro-2-hydroxyphenyl)-3-(2-(3-(5-f...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209489 ((3R)-3-(3,5-dichloro-2-hydroxyphenyl)-3-(2-(3-(5-f...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209487 ((3S)-3-(5-chloro-2-hydroxy-3-iodophenyl)-3-(2-(3-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209469 ((S)-3-bromo-5-chloro-2-hydroxy-b-[[2-[[[3-hydroxy-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mineralocorticoid receptor (Homo sapiens (Human)) | BDBM50324200 (4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assay | J Med Chem 53: 5979-6002 (2010) Article DOI: 10.1021/jm100505n BindingDB Entry DOI: 10.7270/Q2T43V2T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209453 ((3R)-3-(5-bromo-3-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209438 ((3R)-3-(3,5-dibromo-2-hydroxyphenyl)-3-(2-(3-(5-hy...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029624 (4-[2-(3-Chloro-4-dimethylamino-phenyl)-cyclopent-1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029595 (4-[2-(3,4-Dichloro-phenyl)-cyclopent-1-enyl]-benze...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029618 (4-(2-(4-methoxyphenyl)cyclopent-1-enyl)benzenesulf...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029596 (4-(2-Benzo[1,3]dioxol-5-yl-cyclopent-1-enyl)-benze...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209452 ((S)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209457 ((3S)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209449 ((3S)-3-(5-bromo-3-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209445 ((3R)-3-(2-(3-amino-5-(5-fluoro-1,4,5,6-tetrahydrop...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029625 (1-methyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209436 ((3R)-3-(5-chloro-2-hydroxy-3-iodophenyl)-3-(2-(3-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029623 (1-chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research & Development Curated by ChEMBL | Assay Description Tested for inhibition against Prostaglandin G/H synthase 2 | J Med Chem 37: 3878-81 (1994) BindingDB Entry DOI: 10.7270/Q26D5S1G | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209424 ((3R)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209474 ((3R)-3-(5-bromo-3-chloro-2-hydroxyphenyl)-3-(2-(3-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209466 ((3R)-3-(5-chloro-2-hydroxy-3-iodophenyl)-3-(2-(3-h...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209468 ((3R)-3-(3,5-dibromo-2-hydroxyphenyl)-3-(2-(3-(5-fl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209458 ((beta1R)-3,5-dichloro-b-[[[[3-[(5-hydroxy-1,4,5,6-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029623 (1-chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029615 (4-[2-(4-Chloro-phenyl)-cyclopent-1-enyl]-benzenesu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research and Development Curated by ChEMBL | Assay Description In vitro inhibition of prostaglandin G/H synthase 2 (COX-2). | J Med Chem 38: 4570-8 (1995) BindingDB Entry DOI: 10.7270/Q23N22D2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50209462 ((R)-3-(3,5-dichloro-2-hydroxyphenyl)-3-(2-(3-hydro...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of alphaVbeta3 integrin receptor expressed in human 293 cells | Bioorg Med Chem 15: 3783-800 (2007) Article DOI: 10.1016/j.bmc.2007.03.034 BindingDB Entry DOI: 10.7270/Q25Q4VR4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM50029625 (1-methyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopent...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Searle Research & Development Curated by ChEMBL | Assay Description Tested for inhibition against Prostaglandin G/H synthase 2 | J Med Chem 37: 3878-81 (1994) BindingDB Entry DOI: 10.7270/Q26D5S1G | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mineralocorticoid receptor (Homo sapiens (Human)) | BDBM50318295 (CHEMBL1097751 | tert-Butyl (4R)-4-(2-Chloro-4-fluo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research& Development Curated by ChEMBL | Assay Description Antagonist activity at Gal4-fused mineralocorticoid receptor expressed in human HuH7 cells assessed as inhibition of aldosterone-induced receptor act... | J Med Chem 53: 4300-4 (2010) Article DOI: 10.1021/jm1002827 BindingDB Entry DOI: 10.7270/Q22R3RV8 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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