Compile Data Set for Download or QSAR

Found 961 hits with Last Name = 'faust' and Initial = 'ka'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (RABBIT)	BDBM50041969 (3-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C31H34N8O2/c1-5-6-11-28-33-27-17-16-23(32-31(41)38(4)20(2)3)18-26(27)30(40)39(28)19-21-12-14-22(15-13-21)24-9-7-8-10-25(24)29-34-36-37-35-29/h7-10,12-18,20H,5-6,11,19H2,1-4H3,(H,32,41)(H,34,35,36,37)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity against AT-1 receptor from rabbit aorta using [125I]-Sar1-Ile8-Ang II without BSA				J Med Chem 36: 3207-10 (1993) BindingDB Entry DOI: 10.7270/Q2QR4W6P
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50041969 (3-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C31H34N8O2/c1-5-6-11-28-33-27-17-16-23(32-31(41)38(4)20(2)3)18-26(27)30(40)39(28)19-21-12-14-22(15-13-21)24-9-7-8-10-25(24)29-34-36-37-35-29/h7-10,12-18,20H,5-6,11,19H2,1-4H3,(H,32,41)(H,34,35,36,37)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [125I]-Sar1-Ile8-AII (without BSA) from type 1 Angiotensin II receptor of rabbit aorta				Bioorg Med Chem Lett 3: 1299-1304 (1993) Article DOI: 10.1016/S0960-894X(00)80335-2 BindingDB Entry DOI: 10.7270/Q29P31KG
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50035445 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C33H28ClF3N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283305 (3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...) Show SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(CC)cc1F Show InChI InChI=1S/C37H37F2N5O5S/c1-5-9-34-42-32-17-15-26(41-37(47)40-22(3)4)20-29(32)36(46)44(34)21-25-14-13-24(19-30(25)38)27-10-7-8-11-33(27)50(48,49)43-35(45)28-16-12-23(6-2)18-31(28)39/h7-8,10-20,22H,5-6,9,21H2,1-4H3,(H,43,45)(H2,40,41,47)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.110	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282470 (CHEMBL353037 | Quinazolinone Analog) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)NC(C)C)cc3c2=O)cc1 Show InChI InChI=1S/C33H39N5O6S/c1-5-7-19-44-33(41)37-45(42,43)29-12-9-8-11-26(29)24-15-13-23(14-16-24)21-38-30(10-6-2)36-28-18-17-25(20-27(28)31(38)39)35-32(40)34-22(3)4/h8-9,11-18,20,22H,5-7,10,19,21H2,1-4H3,(H,37,41)(H2,34,35,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50283319 (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC1CC1 Show InChI InChI=1S/C36H42FN5O6S/c1-5-6-11-33-39-31-17-16-27(38-35(44)41(4)23(2)3)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-9-7-8-10-32(28)49(46,47)40-36(45)48-19-18-24-12-13-24/h7-10,14-17,20-21,23-24H,5-6,11-13,18-19,22H2,1-4H3,(H,38,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283317 (2-Propyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonyla...) Show SMILES CCCc1nc2ccc(NC(=O)N3CCOCC3)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C35H40FN5O7S/c1-4-7-32-38-30-13-12-26(37-34(43)40-15-18-47-19-16-40)21-28(30)33(42)41(32)22-25-11-10-24(20-29(25)36)27-8-5-6-9-31(27)49(45,46)39-35(44)48-17-14-23(2)3/h5-6,8-13,20-21,23H,4,7,14-19,22H2,1-3H3,(H,37,43)(H,39,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039862 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1F Show InChI InChI=1S/C33H28F4N4O4S/c1-2-3-16-30-38-41(28-14-8-6-12-26(28)33(35,36)37)32(43)40(30)21-22-17-19-23(20-18-22)24-10-5-9-15-29(24)46(44,45)39-31(42)25-11-4-7-13-27(25)34/h4-15,17-20H,2-3,16,21H2,1H3,(H,39,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283300 (2-Butyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonylam...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C36H44FN5O6S/c1-7-8-13-33-39-31-17-16-27(38-35(44)41(6)24(4)5)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-11-9-10-12-32(28)49(46,47)40-36(45)48-19-18-23(2)3/h9-12,14-17,20-21,23-24H,7-8,13,18-19,22H2,1-6H3,(H,38,44)(H,40,45)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283310 (4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...) Show SMILES CCc1ccc(cc1)C(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)c(F)c1 Show InChI InChI=1S/C37H38FN5O5S/c1-6-24-12-14-25(15-13-24)35(44)41-49(47,48)33-11-9-8-10-29(33)26-16-17-27(31(38)20-26)22-43-34(7-2)40-32-19-18-28(21-30(32)36(43)45)39-37(46)42(5)23(3)4/h8-21,23H,6-7,22H2,1-5H3,(H,39,46)(H,41,44)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283312 (4'-[2-Ethyl-6-(3-isopropyl-ureido)-4-oxo-4H-quinaz...) Show SMILES CCc1ccc(C(=O)NS(=O)(=O)c2ccccc2-c2ccc(Cn3c(CC)nc4ccc(NC(=O)NC(C)C)cc4c3=O)c(F)c2)c(F)c1 Show InChI InChI=1S/C36H35F2N5O5S/c1-5-22-11-15-27(30(38)17-22)34(44)42-49(47,48)32-10-8-7-9-26(32)23-12-13-24(29(37)18-23)20-43-33(6-2)41-31-16-14-25(19-28(31)35(43)45)40-36(46)39-21(3)4/h7-19,21H,5-6,20H2,1-4H3,(H,42,44)(H2,39,40,46)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282468 (4'-[2-Butyl-6-(3-isopropyl-ureido)-4-oxo-4H-quinaz...) Show SMILES CCCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C36H37N5O5S/c1-4-5-15-33-39-31-21-20-28(38-36(44)37-24(2)3)22-30(31)35(43)41(33)23-25-16-18-26(19-17-25)29-13-9-10-14-32(29)47(45,46)40-34(42)27-11-7-6-8-12-27/h6-14,16-22,24H,4-5,15,23H2,1-3H3,(H,40,42)(H2,37,38,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039880 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1CCCCC1 Show InChI InChI=1S/C33H35F3N4O4S/c1-2-3-17-30-37-40(28-15-9-8-14-27(28)33(34,35)36)32(42)39(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)45(43,44)38-31(41)25-11-5-4-6-12-25/h7-10,13-16,18-21,25H,2-6,11-12,17,22H2,1H3,(H,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282453 (CHEMBL353800 | Quinazolinone Analog) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)NC(C)C)cc3c2=O)cc1 Show InChI InChI=1S/C34H41N5O6S/c1-5-7-13-31-37-29-19-18-26(36-33(41)35-23(3)4)21-28(29)32(40)39(31)22-24-14-16-25(17-15-24)27-11-9-10-12-30(27)46(43,44)38-34(42)45-20-8-6-2/h9-12,14-19,21,23H,5-8,13,20,22H2,1-4H3,(H,38,42)(H2,35,36,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039929 (2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NS(=O)(=O)C(C)C Show InChI InChI=1S/C29H31F3N4O5S2/c1-4-5-14-27-33-36(25-12-8-7-11-24(25)29(30,31)32)28(37)35(27)19-21-15-17-22(18-16-21)23-10-6-9-13-26(23)43(40,41)34-42(38,39)20(2)3/h6-13,15-18,20,34H,4-5,14,19H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283316 (3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...) Show SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)COCC(C)C Show InChI InChI=1S/C34H40FN5O6S/c1-6-9-31-38-29-15-14-25(37-34(43)36-22(4)5)17-27(29)33(42)40(31)18-24-13-12-23(16-28(24)35)26-10-7-8-11-30(26)47(44,45)39-32(41)20-46-19-21(2)3/h7-8,10-17,21-22H,6,9,18-20H2,1-5H3,(H,39,41)(H2,36,37,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282466 (CHEMBL354779 | Quinazolinone Analog) Show SMILES CCCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)NC(C)C)cc3c2=O)cc1 Show InChI InChI=1S/C35H43N5O6S/c1-5-7-11-21-46-35(43)39-47(44,45)31-13-10-9-12-28(31)26-17-15-25(16-18-26)23-40-32(14-8-6-2)38-30-20-19-27(22-29(30)33(40)41)37-34(42)36-24(3)4/h9-10,12-13,15-20,22,24H,5-8,11,14,21,23H2,1-4H3,(H,39,43)(H2,36,37,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039882 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc(C)oc1C(F)(F)F Show InChI InChI=1S/C33H28F6N4O5S/c1-3-4-13-28-40-43(26-11-7-6-10-25(26)32(34,35)36)31(45)42(28)19-21-14-16-22(17-15-21)23-9-5-8-12-27(23)49(46,47)41-30(44)24-18-20(2)48-29(24)33(37,38)39/h5-12,14-18H,3-4,13,19H2,1-2H3,(H,41,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039887 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1cc2ccccc2o1 Show InChI InChI=1S/C35H29F3N4O5S/c1-2-3-16-32-39-42(28-13-7-6-12-27(28)35(36,37)38)34(44)41(32)22-23-17-19-24(20-18-23)26-11-5-9-15-31(26)48(45,46)40-33(43)30-21-25-10-4-8-14-29(25)47-30/h4-15,17-21H,2-3,16,22H2,1H3,(H,40,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50042565 (5-Butyl-2-(2,6-dichloro-phenyl)-4-[2'-(1H-tetrazol...) Show SMILES CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1c(Cl)cccc1Cl |(-6.39,-5.83,;-4.86,-5.84,;-4.08,-4.52,;-2.54,-4.53,;-1.61,-3.29,;-2.1,-1.82,;-.85,-.9,;.39,-1.82,;1.86,-1.35,;2.18,.16,;3.35,-2.08,;-.08,-3.29,;.81,-4.53,;2.36,-4.52,;3.12,-5.86,;4.66,-5.84,;5.42,-4.52,;4.63,-3.2,;3.1,-3.2,;6.96,-4.5,;7.72,-5.84,;9.27,-5.84,;10.01,-4.5,;9.25,-3.16,;7.71,-3.16,;7.18,-1.7,;8.42,-.81,;7.94,.66,;6.41,.66,;5.94,-.81,;-1.26,.59,;-2.73,.98,;-3.86,-.07,;-3.12,2.44,;-2.04,3.56,;-.56,3.14,;-.16,1.68,;1.25,1.9,)| Show InChI InChI=1S/C28H24Cl2N6O2/c1-2-3-11-24-21(25(28(37)38)36(33-24)26-22(29)9-6-10-23(26)30)16-17-12-14-18(15-13-17)19-7-4-5-8-20(19)27-31-34-35-32-27/h4-10,12-15H,2-3,11,16H2,1H3,(H,37,38)(H,31,32,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3595-605 (1994) BindingDB Entry DOI: 10.7270/Q25Q4V5H
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282472 (CHEMBL169221 | Quinazolinone Analog) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)NCC)cc3c2=O)cc1 Show InChI InChI=1S/C32H37N5O6S/c1-4-7-19-43-32(40)36-44(41,42)28-12-9-8-11-25(28)23-15-13-22(14-16-23)21-37-29(10-5-2)35-27-18-17-24(20-26(27)30(37)38)34-31(39)33-6-3/h8-9,11-18,20H,4-7,10,19,21H2,1-3H3,(H,36,40)(H2,33,34,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282464 (CHEMBL169568 | Quinazolinone Analog) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)NCCC)cc3c2=O)cc1 Show InChI InChI=1S/C33H39N5O6S/c1-4-7-20-44-33(41)37-45(42,43)29-12-9-8-11-26(29)24-15-13-23(14-16-24)22-38-30(10-5-2)36-28-18-17-25(21-27(28)31(38)39)35-32(40)34-19-6-3/h8-9,11-18,21H,4-7,10,19-20,22H2,1-3H3,(H,37,41)(H2,34,35,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50283312 (4'-[2-Ethyl-6-(3-isopropyl-ureido)-4-oxo-4H-quinaz...) Show SMILES CCc1ccc(C(=O)NS(=O)(=O)c2ccccc2-c2ccc(Cn3c(CC)nc4ccc(NC(=O)NC(C)C)cc4c3=O)c(F)c2)c(F)c1 Show InChI InChI=1S/C36H35F2N5O5S/c1-5-22-11-15-27(30(38)17-22)34(44)42-49(47,48)32-10-8-7-9-26(32)23-12-13-24(29(37)18-23)20-43-33(6-2)41-31-16-14-25(19-28(31)35(43)45)40-36(46)39-21(3)4/h7-19,21H,5-6,20H2,1-4H3,(H,42,44)(H2,39,40,46)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282462 (CHEMBL352503 | Quinazolinone Analog) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)CCCC)cc3c2=O)cc1 Show InChI InChI=1S/C34H40N4O6S/c1-4-7-14-32(39)35-26-19-20-29-28(22-26)33(40)38(31(36-29)11-6-3)23-24-15-17-25(18-16-24)27-12-9-10-13-30(27)45(42,43)37-34(41)44-21-8-5-2/h9-10,12-13,15-20,22H,4-8,11,14,21,23H2,1-3H3,(H,35,39)(H,37,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039930 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1occ(Cl)c1Cl Show InChI InChI=1S/C31H25Cl2F3N4O5S/c1-2-3-12-26-37-40(24-10-6-5-9-22(24)31(34,35)36)30(42)39(26)17-19-13-15-20(16-14-19)21-8-4-7-11-25(21)46(43,44)38-29(41)28-27(33)23(32)18-45-28/h4-11,13-16,18H,2-3,12,17H2,1H3,(H,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50283318 (2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulph...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)c(F)c1 Show InChI InChI=1S/C35H42FN5O6S/c1-6-8-14-32-38-30-18-17-26(37-34(43)40(5)23(3)4)21-28(30)33(42)41(32)22-25-16-15-24(20-29(25)36)27-12-10-11-13-31(27)48(45,46)39-35(44)47-19-9-7-2/h10-13,15-18,20-21,23H,6-9,14,19,22H2,1-5H3,(H,37,43)(H,39,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50283305 (3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...) Show SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(CC)cc1F Show InChI InChI=1S/C37H37F2N5O5S/c1-5-9-34-42-32-17-15-26(41-37(47)40-22(3)4)20-29(32)36(46)44(34)21-25-14-13-24(19-30(25)38)27-10-7-8-11-33(27)50(48,49)43-35(45)28-16-12-23(6-2)18-31(28)39/h7-8,10-20,22H,5-6,9,21H2,1-4H3,(H,43,45)(H2,40,41,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1/Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50229575 (CHEMBL2369937) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(C)=O |r,wU:44.47,28.30,48.58,8.15,59.62,2.2,69.72,wD:4.4,18.26,32.43,76.78,(6.67,-4.52,;6.33,-6.02,;4.86,-6.48,;3.73,-5.43,;4.52,-7.98,;5.65,-9.02,;7.12,-8.57,;7.46,-7.07,;8.26,-9.61,;7.92,-11.11,;6.45,-11.57,;5.21,-10.65,;3.95,-11.54,;4.41,-13.01,;5.95,-13.03,;9.73,-9.16,;10.86,-10.2,;10.52,-11.7,;12.33,-9.74,;12.67,-8.24,;11.54,-7.2,;11.72,-5.67,;10.32,-5.02,;9.27,-6.15,;10.03,-7.5,;13.46,-10.79,;14.93,-10.33,;15.27,-8.83,;16.06,-11.38,;17.53,-10.92,;18.66,-11.96,;18.32,-13.47,;20.13,-11.51,;20.47,-10,;19.34,-8.96,;17.87,-9.42,;16.74,-8.37,;17.08,-6.87,;15.95,-5.82,;18.55,-6.41,;19.68,-7.46,;21.26,-12.55,;22.73,-12.09,;23.07,-10.59,;23.87,-13.14,;25.34,-12.68,;26.47,-13.73,;26.13,-15.23,;27.94,-13.27,;29.07,-14.31,;28.73,-15.82,;27.26,-16.27,;26.92,-17.78,;25.45,-18.23,;24.32,-17.19,;25.11,-19.74,;28.28,-11.77,;29.75,-11.31,;30.88,-12.36,;30.09,-9.81,;31.56,-9.35,;31.9,-7.85,;30.77,-6.8,;33.37,-7.39,;28.96,-8.76,;27.49,-9.22,;23.53,-14.64,;22.06,-15.1,;24.66,-15.69,;15.72,-12.88,;16.85,-13.92,;14.25,-13.34,;13.12,-12.29,;3.05,-8.44,;2.71,-9.94,;1.92,-7.39,;.45,-7.85,;-.68,-6.8,;-2.15,-7.26,;-3.28,-6.22,;-4.75,-6.67,;-5.09,-8.18,;-3.96,-9.22,;-2.49,-8.76,;.11,-9.35,;-1.36,-9.81,;1.24,-10.4,)| Show InChI InChI=1S/C59H86N16O12/c1-9-33(5)49(57(86)69-42(35(7)76)23-36-15-12-11-13-16-36)75-55(84)46(26-39-29-64-31-67-39)70-53(82)45(25-38-28-63-30-66-38)72-58(87)50(34(6)10-2)74-54(83)44(24-37-18-20-40(77)21-19-37)71-56(85)48(32(3)4)73-51(80)41(17-14-22-65-59(60)61)68-52(81)43(62-8)27-47(78)79/h11-13,15-16,18-21,28-34,41-46,48-50,62,77H,9-10,14,17,22-27H2,1-8H3,(H,63,66)(H,64,67)(H,68,81)(H,69,86)(H,70,82)(H,71,85)(H,72,87)(H,73,80)(H,74,83)(H,75,84)(H,78,79)(H4,60,61,65)/t33-,34-,41-,42-,43-,44-,45-,46-,48-,49-,50-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Exploratory Chemistry Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards Angiotensin receptor from rabbit aorta				J Med Chem 34: 2919-22 (1991) BindingDB Entry DOI: 10.7270/Q26Q20H6
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039895 (2-{4-[3-butyl-5-oxo-1-(2-trifluoromethylphenyl)-4,...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C32H29F3N4O5S2/c1-2-3-17-30-36-39(28-15-9-8-14-27(28)32(33,34)35)31(40)38(30)22-23-18-20-24(21-19-23)26-13-7-10-16-29(26)46(43,44)37-45(41,42)25-11-5-4-6-12-25/h4-16,18-21,37H,2-3,17,22H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50038189 (4'-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C30H28N4O3S/c1-4-27-32-28-20(2)18-21(3)31-29(28)34(27)19-22-14-16-23(17-15-22)25-12-8-9-13-26(25)38(36,37)33-30(35)24-10-6-5-7-11-24/h5-18H,4,19H2,1-3H3,(H,33,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity of the compound for angiotensin II AT1 receptor in rabbit aorta				J Med Chem 37: 4068-72 (1995) BindingDB Entry DOI: 10.7270/Q2DV1HZ3
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283302 (2-ethyl-3-(3-fluoro-2'-(3-methyl-butyloxycarbonyla...) Show SMILES CCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C34H40FN5O6S/c1-7-31-37-29-15-14-25(36-33(42)39(6)22(4)5)19-27(29)32(41)40(31)20-24-13-12-23(18-28(24)35)26-10-8-9-11-30(26)47(44,45)38-34(43)46-17-16-21(2)3/h8-15,18-19,21-22H,7,16-17,20H2,1-6H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282431 (Acyl sulfonamide derivative | CHEMBL350121) Show SMILES CCCCCCCC(=O)NS(=O)(=O)Nc1ccccc1-c1ccc(Cn2c(CCCC)ncc2C(O)=O)cc1 Show InChI InChI=1S/C29H38N4O5S/c1-3-5-7-8-9-15-28(34)32-39(37,38)31-25-13-11-10-12-24(25)23-18-16-22(17-19-23)21-33-26(29(35)36)20-30-27(33)14-6-4-2/h10-13,16-20,31H,3-9,14-15,21H2,1-2H3,(H,32,34)(H,35,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin II receptor, type 1 to displace 125I-Sar,Ile8-AII in rabbit aorta				Bioorg Med Chem Lett 4: 69-74 (1994) Article DOI: 10.1016/S0960-894X(01)81124-0 BindingDB Entry DOI: 10.7270/Q2NS0TVK
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50042571 (2-Benzyl-5-butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...) Show SMILES CCCCc1nn(Cc2ccccc2)c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C29H28N6O2/c1-2-3-13-26-25(27(29(36)37)35(32-26)19-21-9-5-4-6-10-21)18-20-14-16-22(17-15-20)23-11-7-8-12-24(23)28-30-33-34-31-28/h4-12,14-17H,2-3,13,18-19H2,1H3,(H,36,37)(H,30,31,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3595-605 (1994) BindingDB Entry DOI: 10.7270/Q25Q4V5H
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283305 (3'-Fluoro-4'-[6-(3-isopropyl-ureido)-4-oxo-2-propy...) Show SMILES CCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccc(CC)cc1F Show InChI InChI=1S/C37H37F2N5O5S/c1-5-9-34-42-32-17-15-26(41-37(47)40-22(3)4)20-29(32)36(46)44(34)21-25-14-13-24(19-30(25)38)27-10-7-8-11-33(27)50(48,49)43-35(45)28-16-12-23(6-2)18-31(28)39/h7-8,10-20,22H,5-6,9,21H2,1-4H3,(H,43,45)(H2,40,41,47)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283300 (2-Butyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonylam...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C36H44FN5O6S/c1-7-8-13-33-39-31-17-16-27(38-35(44)41(6)24(4)5)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-11-9-10-12-32(28)49(46,47)40-36(45)48-19-18-23(2)3/h9-12,14-17,20-21,23-24H,7-8,13,18-19,22H2,1-6H3,(H,38,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039921 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1occc1C Show InChI InChI=1S/C32H29F3N4O5S/c1-3-4-13-28-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(28)20-22-14-16-23(17-15-22)24-9-5-8-12-27(24)45(42,43)37-30(40)29-21(2)18-19-44-29/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282455 (CHEMBL169967 | Quinazolinone Analog) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)cc1 Show InChI InChI=1S/C34H41N5O6S/c1-6-8-20-45-34(42)37-46(43,44)30-13-10-9-12-27(30)25-16-14-24(15-17-25)22-39-31(11-7-2)36-29-19-18-26(21-28(29)32(39)40)35-33(41)38(5)23(3)4/h9-10,12-19,21,23H,6-8,11,20,22H2,1-5H3,(H,35,41)(H,37,42)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50038190 (4'-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...) Show SMILES CCc1nc2c(C)cc(C)nc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C(C)C Show InChI InChI=1S/C27H30N4O3S/c1-6-24-29-25-18(4)15-19(5)28-26(25)31(24)16-20-11-13-21(14-12-20)22-9-7-8-10-23(22)35(33,34)30-27(32)17(2)3/h7-15,17H,6,16H2,1-5H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity of the compound for angiotensin II AT1 receptor in rabbit aorta				J Med Chem 37: 4068-72 (1995) BindingDB Entry DOI: 10.7270/Q2DV1HZ3
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283307 (4'-[2-Ethyl-6-(3-isopropyl-3-methyl-ureido)-4-oxo-...) Show SMILES CCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)COCC(C)C Show InChI InChI=1S/C34H40FN5O6S/c1-7-31-37-29-15-14-25(36-34(43)39(6)22(4)5)17-27(29)33(42)40(31)18-24-13-12-23(16-28(24)35)26-10-8-9-11-30(26)47(44,45)38-32(41)20-46-19-21(2)3/h8-17,21-22H,7,18-20H2,1-6H3,(H,36,43)(H,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (RAT)	BDBM50283300 (2-Butyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonylam...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C36H44FN5O6S/c1-7-8-13-33-39-31-17-16-27(38-35(44)41(6)24(4)5)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-11-9-10-12-32(28)49(46,47)40-36(45)48-19-18-23(2)3/h9-12,14-17,20-21,23-24H,7-8,13,18-19,22H2,1-6H3,(H,38,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039899 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1oc(C)cc1C Show InChI InChI=1S/C33H31F3N4O5S/c1-4-5-14-29-37-40(27-12-8-7-11-26(27)33(34,35)36)32(42)39(29)20-23-15-17-24(18-16-23)25-10-6-9-13-28(25)46(43,44)38-31(41)30-21(2)19-22(3)45-30/h6-13,15-19H,4-5,14,20H2,1-3H3,(H,38,41)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50039946 (4'-[3-Butyl-5-oxo-1-(2-trifluoromethyl-phenyl)-1,5...) Show SMILES CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)C1(C)SCCS1 Show InChI InChI=1S/C31H31F3N4O4S3/c1-3-4-13-27-35-38(25-11-7-6-10-24(25)31(32,33)34)29(40)37(27)20-21-14-16-22(17-15-21)23-9-5-8-12-26(23)45(41,42)36-28(39)30(2)43-18-19-44-30/h5-12,14-17H,3-4,13,18-20H2,1-2H3,(H,36,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against angiotensin II rabbit aorta AT1 receptor using radioligand [125I]-Sar Ile-AII				J Med Chem 37: 2808-24 (1994) BindingDB Entry DOI: 10.7270/Q2M907QM
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor A/B (RAT)	BDBM50283319 (2-Butyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC1CC1 Show InChI InChI=1S/C36H42FN5O6S/c1-5-6-11-33-39-31-17-16-27(38-35(44)41(4)23(2)3)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-9-7-8-10-32(28)49(46,47)40-36(45)48-19-18-24-12-13-24/h7-10,14-17,20-21,23-24H,5-6,11-13,18-19,22H2,1-4H3,(H,38,44)(H,40,45)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50283300 (2-Butyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonylam...) Show SMILES CCCCc1nc2ccc(NC(=O)N(C)C(C)C)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C36H44FN5O6S/c1-7-8-13-33-39-31-17-16-27(38-35(44)41(6)24(4)5)21-29(31)34(43)42(33)22-26-15-14-25(20-30(26)37)28-11-9-10-12-32(28)49(46,47)40-36(45)48-19-18-23(2)3/h9-12,14-17,20-21,23-24H,7-8,13,18-19,22H2,1-6H3,(H,38,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50283317 (2-Propyl-3-(3-fluoro-2'-(3-methylbutyloxycarbonyla...) Show SMILES CCCc1nc2ccc(NC(=O)N3CCOCC3)cc2c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCCC(C)C Show InChI InChI=1S/C35H40FN5O7S/c1-4-7-32-38-30-13-12-26(37-34(43)40-15-18-47-19-16-40)21-28(30)33(42)41(32)22-25-11-10-24(20-29(25)36)27-8-5-6-9-31(27)49(45,46)39-35(44)48-17-14-23(2)3/h5-6,8-13,20-21,23H,4,7,14-19,22H2,1-3H3,(H,37,43)(H,39,44)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50049181 (2-Butyl-3-(2'-(butyloxycarbonylaminosulphonyl)-bip...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)cc1 Show InChI InChI=1S/C35H43N5O6S/c1-6-8-14-32-37-30-20-19-27(36-34(42)39(5)24(3)4)22-29(30)33(41)40(32)23-25-15-17-26(18-16-25)28-12-10-11-13-31(28)47(44,45)38-35(43)46-21-9-7-2/h10-13,15-20,22,24H,6-9,14,21,23H2,1-5H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membrane				Bioorg Med Chem Lett 4: 2337-2342 (1994) Article DOI: 10.1016/0960-894X(94)85036-4 BindingDB Entry DOI: 10.7270/Q2X066Z9
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50049181 (2-Butyl-3-(2'-(butyloxycarbonylaminosulphonyl)-bip...) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)cc1 Show InChI InChI=1S/C35H43N5O6S/c1-6-8-14-32-37-30-20-19-27(36-34(42)39(5)24(3)4)22-29(30)33(41)40(32)23-25-15-17-26(18-16-25)28-12-10-11-13-31(28)47(44,45)38-35(43)46-21-9-7-2/h10-13,15-20,22,24H,6-9,14,21,23H2,1-5H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50042578 (5-Butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...) Show SMILES CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C29H25F3N6O2/c1-2-3-11-24-22(26(28(39)40)38(35-24)25-12-7-6-10-23(25)29(30,31)32)17-18-13-15-19(16-14-18)20-8-4-5-9-21(20)27-33-36-37-34-27/h4-10,12-16H,2-3,11,17H2,1H3,(H,39,40)(H,33,34,36,37)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3595-605 (1994) BindingDB Entry DOI: 10.7270/Q25Q4V5H
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50282452 (CHEMBL169488 | Quinazolinone Analog) Show SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)NCC)cc3c2=O)cc1 Show InChI InChI=1S/C33H39N5O6S/c1-4-7-13-30-36-28-19-18-25(35-32(40)34-6-3)21-27(28)31(39)38(30)22-23-14-16-24(17-15-23)26-11-9-10-12-29(26)45(42,43)37-33(41)44-20-8-5-2/h9-12,14-19,21H,4-8,13,20,22H2,1-3H3,(H,37,41)(H2,34,35,40)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for binding affinity against Angiotensin II receptor, type 1 in rabbit aortic membrane				Bioorg Med Chem Lett 4: 81-86 (1994) Article DOI: 10.1016/S0960-894X(01)81126-4 BindingDB Entry DOI: 10.7270/Q2D79BBS
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (RABBIT)	BDBM50042570 (5-Butyl-2-phenethyl-4-[2'-(1H-tetrazol-5-yl)-biphe...) Show SMILES CCCCc1nn(CCc2ccccc2)c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C30H30N6O2/c1-2-3-13-27-26(28(30(37)38)36(33-27)19-18-21-9-5-4-6-10-21)20-22-14-16-23(17-15-22)24-11-7-8-12-25(24)29-31-34-35-32-29/h4-12,14-17H,2-3,13,18-20H2,1H3,(H,37,38)(H,31,32,34,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1				J Med Chem 36: 3595-605 (1994) BindingDB Entry DOI: 10.7270/Q25Q4V5H
					More data for this Ligand-Target Pair

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