Compile Data Set for Download or QSAR

Found 149 hits with Last Name = 'vimal' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526962 (CHEMBL4448056) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2cc(ccc2n1CC1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C24H30N4O3/c1-17-13-19(16-26(2)24(17)29)23-25-21-14-20(27-7-11-31-12-8-27)3-4-22(21)28(23)15-18-5-9-30-10-6-18/h3-4,13-14,16,18H,5-12,15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415889 (CHEMBL1098723) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccc(cc1)C(N)=O Show InChI InChI=1S/C21H20ClFN4O2/c1-12-18(10-20(28)25-11-15-3-6-16(23)9-19(15)22)13(2)27(26-12)17-7-4-14(5-8-17)21(24)29/h3-9H,10-11H2,1-2H3,(H2,24,29)(H,25,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526964 (CHEMBL4438171) Show SMILES COCC(COC)n1c(nc2cc(ccc12)N1CCOCC1)-c1cc(C)c(=O)n(C)c1 Show InChI InChI=1S/C23H30N4O4/c1-16-11-17(13-25(2)23(16)28)22-24-20-12-18(26-7-9-31-10-8-26)5-6-21(20)27(22)19(14-29-3)15-30-4/h5-6,11-13,19H,7-10,14-15H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415882 (CHEMBL1094106) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C14H15ClFN3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(16)5-13(10)15/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.9	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415908 (CHEMBL1094641) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1cccc(Cl)c1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19Cl2N3O/c1-13-17(14(2)25(24-13)16-8-4-3-5-9-16)11-19(26)23-12-15-7-6-10-18(21)20(15)22/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526959 (CHEMBL4522991) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CC1CCCOC1 Show InChI InChI=1S/C20H23N3O2/c1-14-10-16(12-22(2)20(14)24)19-21-17-7-3-4-8-18(17)23(19)11-15-6-5-9-25-13-15/h3-4,7-8,10,12,15H,5-6,9,11,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526959 (CHEMBL4522991) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CC1CCCOC1 Show InChI InChI=1S/C20H23N3O2/c1-14-10-16(12-22(2)20(14)24)19-21-17-7-3-4-8-18(17)23(19)11-15-6-5-9-25-13-15/h3-4,7-8,10,12,15H,5-6,9,11,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415883 (CHEMBL1095454) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526961 (CHEMBL4576013) Show SMILES COCC(COC)n1c(nc2ccccc12)-c1cc(C)c(=O)n(C)c1 Show InChI InChI=1S/C19H23N3O3/c1-13-9-14(10-21(2)19(13)23)18-20-16-7-5-6-8-17(16)22(18)15(11-24-3)12-25-4/h5-10,15H,11-12H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526950 (CHEMBL4547614) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CCC1CCOCC1 Show InChI InChI=1S/C21H25N3O2/c1-15-13-17(14-23(2)21(15)25)20-22-18-5-3-4-6-19(18)24(20)10-7-16-8-11-26-12-9-16/h3-6,13-14,16H,7-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526967 (CHEMBL4579229) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CC1CC2(COC2)C1 Show InChI InChI=1S/C21H23N3O2/c1-14-7-16(11-23(2)20(14)25)19-22-17-5-3-4-6-18(17)24(19)10-15-8-21(9-15)12-26-13-21/h3-7,11,15H,8-10,12-13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415892 (CHEMBL1094411) Show SMILES Cc1nc(-c2ccccc2)n(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(25(2)20(24-13)14-6-4-3-5-7-14)11-19(26)23-12-15-8-9-16(22)10-17(15)21/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415888 (CHEMBL1096314) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ncccn1 Show InChI InChI=1S/C18H17ClFN5O/c1-11-15(12(2)25(24-11)18-21-6-3-7-22-18)9-17(26)23-10-13-4-5-14(20)8-16(13)19/h3-8H,9-10H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415788 (CHEMBL1093772) Show SMILES CCn1ncc2c(Cl)c(cnc12)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C17H13Cl2F3N4O/c1-2-26-15-10(8-25-26)14(19)11(7-23-15)16(27)24-6-9-3-4-13(18)12(5-9)17(20,21)22/h3-5,7-8H,2,6H2,1H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415891 (CHEMBL1094744) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H18Cl2FN3O/c1-12-18(13(2)26(25-12)17-7-4-15(21)5-8-17)10-20(27)24-11-14-3-6-16(23)9-19(14)22/h3-9H,10-11H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415789 (CHEMBL1093773) Show SMILES Cc1nn(C)c2ncc(C(=O)NCc3ccc(Cl)c(c3)C(F)(F)F)c(Cl)c12 Show InChI InChI=1S/C17H13Cl2F3N4O/c1-8-13-14(19)10(7-23-15(13)26(2)25-8)16(27)24-6-9-3-4-12(18)11(5-9)17(20,21)22/h3-5,7H,6H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.1	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526963 (CHEMBL4456922) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CC1CCOCC1 Show InChI InChI=1S/C20H23N3O2/c1-14-11-16(13-22(2)20(14)24)19-21-17-5-3-4-6-18(17)23(19)12-15-7-9-25-10-8-15/h3-6,11,13,15H,7-10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526971 (CHEMBL4570497) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1C[C@H]1CC[C@H](O)CC1 |r,wU:19.21,wD:22.25,(17.38,-54.83,;16.61,-53.5,;15.07,-53.5,;14.29,-52.17,;15.05,-50.84,;16.58,-50.82,;17.34,-49.48,;17.37,-52.16,;18.91,-52.15,;12.75,-52.18,;11.86,-53.44,;10.39,-52.97,;9.04,-53.75,;7.71,-52.98,;7.71,-51.43,;9.04,-50.66,;10.38,-51.42,;11.84,-50.94,;12.31,-49.47,;11.27,-48.33,;9.76,-48.67,;8.73,-47.52,;9.2,-46.06,;8.16,-44.91,;10.7,-45.73,;11.73,-46.87,)| Show InChI InChI=1S/C21H25N3O2/c1-14-11-16(13-23(2)21(14)26)20-22-18-5-3-4-6-19(18)24(20)12-15-7-9-17(25)10-8-15/h3-6,11,13,15,17,25H,7-10,12H2,1-2H3/t15-,17-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415909 (CHEMBL1094482) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(Cl)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19Cl2N3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(21)10-19(15)22/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50415883 (CHEMBL1095454) Show SMILES Cc1nn(c(C)c1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C20H19ClFN3O/c1-13-18(14(2)25(24-13)17-6-4-3-5-7-17)11-20(26)23-12-15-8-9-16(22)10-19(15)21/h3-10H,11-12H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of rat P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415790 (CHEMBL1093774 | GSK-1564023A | US10272074, Example...) Show SMILES Cc1noc(C)c1-c1ccc(CNC(=O)c2cnc3n(C)nc(C)c3c2Cl)cc1 Show InChI InChI=1S/C21H20ClN5O2/c1-11-18-19(22)16(10-23-20(18)27(4)25-11)21(28)24-9-14-5-7-15(8-6-14)17-12(2)26-29-13(17)3/h5-8,10H,9H2,1-4H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415890 (CHEMBL1098722) Show SMILES COc1ccc(cc1)-n1nc(C)c(CC(=O)NCc2ccc(F)cc2Cl)c1C Show InChI InChI=1S/C21H21ClFN3O2/c1-13-19(11-21(27)24-12-15-4-5-16(23)10-20(15)22)14(2)26(25-13)17-6-8-18(28-3)9-7-17/h4-10H,11-12H2,1-3H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415906 (CHEMBL1096096) Show SMILES Cc1nn(c(C)c1CC(=O)NC(C)(C)c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C22H25N3O/c1-16-20(17(2)25(24-16)19-13-9-6-10-14-19)15-21(26)23-22(3,4)18-11-7-5-8-12-18/h5-14H,15H2,1-4H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415886 (CHEMBL1096047) Show SMILES Cc1nn(Cc2cccnc2)c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C20H20ClFN4O/c1-13-18(14(2)26(25-13)12-15-4-3-7-23-10-15)9-20(27)24-11-16-5-6-17(22)8-19(16)21/h3-8,10H,9,11-12H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526952 (CHEMBL4457453) Show SMILES CNC(=O)c1ccc2n(CC3CCN(CC3)C(=O)c3ccccc3)c(nc2c1)-c1cc(C)c(O)c(C)c1 Show InChI InChI=1S/C30H32N4O3/c1-19-15-24(16-20(2)27(19)35)28-32-25-17-23(29(36)31-3)9-10-26(25)34(28)18-21-11-13-33(14-12-21)30(37)22-7-5-4-6-8-22/h4-10,15-17,21,35H,11-14,18H2,1-3H3,(H,31,36)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415898 (CHEMBL1096100) Show SMILES Cc1nn(cc1CC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C19H17ClFN3O/c1-13-15(12-24(23-13)17-5-3-2-4-6-17)9-19(25)22-11-14-7-8-16(21)10-18(14)20/h2-8,10,12H,9,11H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Rattus norvegicus (Rat))	BDBM50415882 (CHEMBL1094106) Show SMILES Cc1n[nH]c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C14H15ClFN3O/c1-8-12(9(2)19-18-8)6-14(20)17-7-10-3-4-11(16)5-13(10)15/h3-5H,6-7H2,1-2H3,(H,17,20)(H,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of rat P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415884 (CHEMBL1096049) Show SMILES Cc1nn(C)c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C15H17ClFN3O/c1-9-13(10(2)20(3)19-9)7-15(21)18-8-11-4-5-12(17)6-14(11)16/h4-6H,7-8H2,1-3H3,(H,18,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415791 (CHEMBL1089404) Show SMILES CCn1ncc2c(Cl)c(cnc12)C(=O)NCc1cc(C)cc(C)c1 Show InChI InChI=1S/C18H19ClN4O/c1-4-23-17-14(10-22-23)16(19)15(9-20-17)18(24)21-8-13-6-11(2)5-12(3)7-13/h5-7,9-10H,4,8H2,1-3H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415905 (CHEMBL1096097) Show SMILES Cc1nn(c(C)c1CC(=O)NC1CCCCCC1)-c1ccccc1 Show InChI InChI=1S/C20H27N3O/c1-15-19(14-20(24)21-17-10-6-3-4-7-11-17)16(2)23(22-15)18-12-8-5-9-13-18/h5,8-9,12-13,17H,3-4,6-7,10-11,14H2,1-2H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415897 (CHEMBL1096029) Show SMILES Cc1c(CC(=O)NCc2ccc(F)cc2Cl)cnn1-c1ccccc1 Show InChI InChI=1S/C19H17ClFN3O/c1-13-15(12-23-24(13)17-5-3-2-4-6-17)9-19(25)22-11-14-7-8-16(21)10-18(14)20/h2-8,10,12H,9,11H2,1H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415913 (CHEMBL1096048) Show SMILES Cc1nn(CCO)c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C16H19ClFN3O2/c1-10-14(11(2)21(20-10)5-6-22)8-16(23)19-9-12-3-4-13(18)7-15(12)17/h3-4,7,22H,5-6,8-9H2,1-2H3,(H,19,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415792 (CHEMBL1089743) Show SMILES COc1cccc(c1)-c1ccccc1CNC(=O)c1cnc2n(C)nc(C)c2c1Cl Show InChI InChI=1S/C23H21ClN4O2/c1-14-20-21(24)19(13-25-22(20)28(2)27-14)23(29)26-12-16-7-4-5-10-18(16)15-8-6-9-17(11-15)30-3/h4-11,13H,12H2,1-3H3,(H,26,29)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415793 (CHEMBL1089744) Show SMILES Cc1nn(C)c2ncc(C(=O)NCc3cc(C)cc(C)c3)c(Cl)c12 Show InChI InChI=1S/C18H19ClN4O/c1-10-5-11(2)7-13(6-10)8-21-18(24)14-9-20-17-15(16(14)19)12(3)22-23(17)4/h5-7,9H,8H2,1-4H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415794 (CHEMBL1093602 | GSK-325971A) Show SMILES CCn1ncc2c(Cl)c(cnc12)C(=O)NCc1ccc(C)cc1C Show InChI InChI=1S/C18H19ClN4O/c1-4-23-17-14(10-22-23)16(19)15(9-20-17)18(24)21-8-13-6-5-11(2)7-12(13)3/h5-7,9-10H,4,8H2,1-3H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526952 (CHEMBL4457453) Show SMILES CNC(=O)c1ccc2n(CC3CCN(CC3)C(=O)c3ccccc3)c(nc2c1)-c1cc(C)c(O)c(C)c1 Show InChI InChI=1S/C30H32N4O3/c1-19-15-24(16-20(2)27(19)35)28-32-25-17-23(29(36)31-3)9-10-26(25)34(28)18-21-11-13-33(14-12-21)30(37)22-7-5-4-6-8-22/h4-10,15-17,21,35H,11-14,18H2,1-3H3,(H,31,36)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526955 (CHEMBL4455610) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CC1CCN(CC1)C(=O)CO Show InChI InChI=1S/C22H26N4O3/c1-15-11-17(13-24(2)22(15)29)21-23-18-5-3-4-6-19(18)26(21)12-16-7-9-25(10-8-16)20(28)14-27/h3-6,11,13,16,27H,7-10,12,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526951 (CHEMBL4593025) Show SMILES CNC(=O)c1ccc2n(CC3CCN(CC3)C(C)=O)c(nc2c1)-c1cc(C)c(O)c(C)c1 Show InChI InChI=1S/C25H30N4O3/c1-15-11-20(12-16(2)23(15)31)24-27-21-13-19(25(32)26-4)5-6-22(21)29(24)14-18-7-9-28(10-8-18)17(3)30/h5-6,11-13,18,31H,7-10,14H2,1-4H3,(H,26,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415807 (CHEMBL1090973) Show SMILES CCCn1nc(C)c2c(Cl)c(cnc12)C(=O)NCc1ccc(cc1)-c1c(C)noc1C Show InChI InChI=1S/C23H24ClN5O2/c1-5-10-29-22-20(13(2)27-29)21(24)18(12-25-22)23(30)26-11-16-6-8-17(9-7-16)19-14(3)28-31-15(19)4/h6-9,12H,5,10-11H2,1-4H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415806 (CHEMBL1094035) Show SMILES CC(C)n1nc(C)c2c(Cl)c(cnc12)C(=O)NCc1ccc(cc1)-c1c(C)noc1C Show InChI InChI=1S/C23H24ClN5O2/c1-12(2)29-22-20(13(3)27-29)21(24)18(11-25-22)23(30)26-10-16-6-8-17(9-7-16)19-14(4)28-31-15(19)5/h6-9,11-12H,10H2,1-5H3,(H,26,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415808 (CHEMBL1091054) Show SMILES Cc1noc(C)c1-c1ccc(CNC(=O)c2cnc3n(Cc4ccccn4)nc(C)c3c2Cl)cc1 Show InChI InChI=1S/C26H23ClN6O2/c1-15-23-24(27)21(13-29-25(23)33(31-15)14-20-6-4-5-11-28-20)26(34)30-12-18-7-9-19(10-8-18)22-16(2)32-35-17(22)3/h4-11,13H,12,14H2,1-3H3,(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415900 (CHEMBL1095783) Show SMILES Cc1nn(c(C)c1NC(=O)NCc1ccc(F)cc1Cl)-c1ccccc1 Show InChI InChI=1S/C19H18ClFN4O/c1-12-18(13(2)25(24-12)16-6-4-3-5-7-16)23-19(26)22-11-14-8-9-15(21)10-17(14)20/h3-10H,11H2,1-2H3,(H2,22,23,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415795 (CHEMBL1089745) Show SMILES CCn1ncc2c(Cl)c(cnc12)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C16H14Cl2N4O/c1-2-22-15-12(9-21-22)14(18)13(8-19-15)16(23)20-7-10-3-5-11(17)6-4-10/h3-6,8-9H,2,7H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50415796 (CHEMBL1089350) Show SMILES CCc1nn(C)c2ncc(C(=O)NCC3Cc4ccccc4C3)c(Cl)c12 Show InChI InChI=1S/C20H21ClN4O/c1-3-16-17-18(21)15(11-22-19(17)25(2)24-16)20(26)23-10-12-8-13-6-4-5-7-14(13)9-12/h4-7,11-12H,3,8-10H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of cortisol-induced renilla luciferase transactiv...				Bioorg Med Chem Lett 20: 2340-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.133 BindingDB Entry DOI: 10.7270/Q2SF2XDJ
					More data for this Ligand-Target Pair
Bromodomain adjacent to zinc finger domain protein 2A (Homo sapiens (Human))	BDBM50526963 (CHEMBL4456922) Show SMILES Cc1cc(cn(C)c1=O)-c1nc2ccccc2n1CC1CCOCC1 Show InChI InChI=1S/C20H23N3O2/c1-14-11-16(13-22(2)20(14)24)19-21-17-5-3-4-6-18(17)23(19)12-15-7-9-25-10-8-15/h3-6,11,13,15H,7-10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Inhibition of BAZ2A (unknown origin) by TR-FRET assay				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50526960 (CHEMBL4475163) Show SMILES COCC(C)n1c(nc2ccccc12)-c1cc(C)c(=O)n(C)c1 Show InChI InChI=1S/C18H21N3O2/c1-12-9-14(10-20(3)18(12)22)17-19-15-7-5-6-8-16(15)21(17)13(2)11-23-4/h5-10,13H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GSK Curated by ChEMBL					Assay Description Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal His6-tagged BRD4 BD1 (1 to 477 residues)/BD2 Y390A mutant incubated...				J Med Chem 63: 714-746 (2020) Article DOI: 10.1021/acs.jmedchem.9b01670 BindingDB Entry DOI: 10.7270/Q2TF01RT
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50414954 (CHEMBL575966) Show SMILES CN(C(=O)c1c(C)onc1-c1ccccc1Cl)c1ccc(Cl)cc1 Show InChI InChI=1S/C18H14Cl2N2O2/c1-11-16(17(21-24-11)14-5-3-4-6-15(14)20)18(23)22(2)13-9-7-12(19)8-10-13/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CYP2C19				J Med Chem 52: 7962-5 (2009) Article DOI: 10.1021/jm901434t BindingDB Entry DOI: 10.7270/Q2Z89DPD
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50414955 (CHEMBL576138) Show SMILES CN(C(=O)c1c(C)onc1-c1ccccc1Cl)c1ccc(C)c(Cl)c1 Show InChI InChI=1S/C19H16Cl2N2O2/c1-11-8-9-13(10-16(11)21)23(3)19(24)17-12(2)25-22-18(17)14-6-4-5-7-15(14)20/h4-10H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of CYP2C19				J Med Chem 52: 7962-5 (2009) Article DOI: 10.1021/jm901434t BindingDB Entry DOI: 10.7270/Q2Z89DPD
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415887 (CHEMBL1095731) Show SMILES Cc1nn(Cc2ccccc2)c(C)c1CC(=O)NCc1ccc(F)cc1Cl Show InChI InChI=1S/C21H21ClFN3O/c1-14-19(15(2)26(25-14)13-16-6-4-3-5-7-16)11-21(27)24-12-17-8-9-18(23)10-20(17)22/h3-10H,11-13H2,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM50415885 (CHEMBL1096660) Show SMILES CN(C)CCn1nc(C)c(CC(=O)NCc2ccc(F)cc2Cl)c1C Show InChI InChI=1S/C18H24ClFN4O/c1-12-16(13(2)24(22-12)8-7-23(3)4)10-18(25)21-11-14-5-6-15(20)9-17(14)19/h5-6,9H,7-8,10-11H2,1-4H3,(H,21,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human P2X7 receptor assessed as inhibition of ethidium bromide accumulation				Bioorg Med Chem Lett 20: 3161-4 (2010) Article DOI: 10.1016/j.bmcl.2010.03.096 BindingDB Entry DOI: 10.7270/Q2W66N1B
					More data for this Ligand-Target Pair

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