Found 316 hits with Last Name = 'majjigapu' and Initial = 'sr' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM34233
(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)Show InChI InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IDO1 using L-tryptophan as substrate preincubated for 5 mins followed by substrate addition measured after 10 mins by... |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM81348
(β-Lapachone (A3) | Beta lapachone | R115 (Rea...)Show InChI InChI=1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H,7-8H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE KEGG PC cid PC sid UniChem
Patents
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of human recombinant IDO1 expressed in Escherichia coli by Michaelis-Menton nonlinear regression plot analysis in presence ... |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50183456
(CHEMBL425403 | N-methyl-N'-9-phenanthrylimidodicar...)Show SMILES CN=C(N)NC(N)=Nc1cc2ccccc2c2ccccc12 |w:7.7,1.0| Show InChI InChI=1S/C17H17N5/c1-20-16(18)22-17(19)21-15-10-11-6-2-3-7-12(11)13-8-4-5-9-14(13)15/h2-10H,1H3,(H5,18,19,20,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IDO1 expressed in yeast IS20-2B using tryptophan as substrate by methylene blue/ascorbate assay |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50279937
(CHEMBL1985550)Show InChI InChI=1S/C9H7N3O2/c10-5-3-6(11)9(14)8-4(5)1-2-7(13)12-8/h1-3,10H,11H2,(H,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Similars
| Article PubMed
| 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human recombinant IDO1 using L-tryptophan as substrate after 15 mins by Dixon plot analysis |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM36371
(5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidaz...)Show InChI InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
| Article PubMed
| 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Competitive inhibition of 6His-tagged human recombinant IDO expressed in Escherichia coli BL21DE3pLys |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50024210
(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)Show InChI InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Noncompetitive inhibition of human recombinant IDO1 expressed in Escherichia coli BL21 by Lineweaver-Burk double-reciprocal plot analysis |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM168435
(US9675571, 129)Show SMILES CC(C)CN(C1CCCCC1)c1ccc(cc1NC(=O)Nc1cc(C)no1)[C@H]1C[C@H]1C(O)=O |r| Show InChI InChI=1S/C25H34N4O4/c1-15(2)14-29(18-7-5-4-6-8-18)22-10-9-17(19-13-20(19)24(30)31)12-21(22)26-25(32)27-23-11-16(3)28-33-23/h9-12,15,18-20H,4-8,13-14H2,1-3H3,(H,30,31)(H2,26,27,32)/t19-,20-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assay |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM317549
(3-(3-(3-(2,4- difluorophenyl)ureido)-4- (diisobuty...)Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(F)cc1F)C(CC(O)=O)C(F)(F)F Show InChI InChI=1S/C25H30F5N3O3/c1-14(2)12-33(13-15(3)4)22-8-5-16(18(11-23(34)35)25(28,29)30)9-21(22)32-24(36)31-20-7-6-17(26)10-19(20)27/h5-10,14-15,18H,11-13H2,1-4H3,(H,34,35)(H2,31,32,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assay |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM340834
(US9765018, Example 287)Show SMILES CCCC(CCC)Oc1c(Br)cc(cc1NC(=O)Nc1ccccc1F)-c1ccccc1-c1nnn[nH]1 Show InChI InChI=1S/C27H28BrFN6O2/c1-3-9-18(10-4-2)37-25-21(28)15-17(19-11-5-6-12-20(19)26-32-34-35-33-26)16-24(25)31-27(36)30-23-14-8-7-13-22(23)29/h5-8,11-16,18H,3-4,9-10H2,1-2H3,(H2,30,31,36)(H,32,33,34,35) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assay |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50500137
(CHEMBL3747340)Show SMILES Cc1ccc(CC(=O)Nc2cc(ccc2N2CC3CC2CN3Cc2ccccc2)-c2ccccc2-c2nnn[nH]2)cc1 |THB:22:21:15.16:18,14:15:21.20:18| Show InChI InChI=1S/C34H33N7O/c1-23-11-13-24(14-12-23)17-33(42)35-31-18-26(29-9-5-6-10-30(29)34-36-38-39-37-34)15-16-32(31)41-22-27-19-28(41)21-40(27)20-25-7-3-2-4-8-25/h2-16,18,27-28H,17,19-22H2,1H3,(H,35,42)(H,36,37,38,39) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 in HEK293 cells after 20 hrs by plate reader assay |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50126143
(Epacadostat | INCB-024360)Show SMILES NS(=O)(=O)NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of IFN-gamma-stimulated IDO1 activity in human HeLa cells using L-tryptophan as substrate after 48 hrs by microplate reader analysis |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391358
(CHEMBL2147989)Show InChI InChI=1S/C8H6ClN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50575464
(CHEMBL4847829) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01968 BindingDB Entry DOI: 10.7270/Q2G164NR |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391359
(CHEMBL2147998)Show InChI InChI=1S/C8H7N3O/c12-8-4-2-1-3-6(8)7-5-9-11-10-7/h1-5,12H,(H,9,10,11) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50530532
(CHEMBL4443463)Show InChI InChI=1S/C8H7ClN4/c9-6-1-3-7(4-2-6)11-8-5-10-13-12-8/h1-5H,(H2,10,11,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of IDO1 (unknown origin) by cell based assay |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM17467
(1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...)Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50530532
(CHEMBL4443463)Show InChI InChI=1S/C8H7ClN4/c9-6-1-3-7(4-2-6)11-8-5-10-13-12-8/h1-5H,(H2,10,11,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of IDO1 (unknown origin) by cell based assay |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391365
(CHEMBL2147990)Show InChI InChI=1S/C9H6N4/c10-5-7-2-1-3-8(4-7)9-6-11-13-12-9/h1-4,6H,(H,11,12,13) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391372
(CHEMBL2147992)Show InChI InChI=1S/C10H11N3/c1-2-8-4-3-5-9(6-8)10-7-11-13-12-10/h3-7H,2H2,1H3,(H,11,12,13) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01968 BindingDB Entry DOI: 10.7270/Q2G164NR |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50355861
(CHEMBL1909733)Show InChI InChI=1S/C8H6BrN3/c9-7-4-2-1-3-6(7)8-5-10-12-11-8/h1-5H,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50575458
(CHEMBL4871312) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01968 BindingDB Entry DOI: 10.7270/Q2G164NR |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50575458
(CHEMBL4871312) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01968 BindingDB Entry DOI: 10.7270/Q2G164NR |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391360
(CHEMBL2147995)Show InChI InChI=1S/C7H5BrN4/c8-7-3-5(1-2-9-7)6-4-10-12-11-6/h1-4H,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysis |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of full-length human IDO1 expressed in Escherichia coli Rosetta (DE3) using L-Trp substrate by HPLC analysis |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50235921
(CHEMBL584991)Show InChI InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50235921
(CHEMBL584991)Show InChI InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of recombinant human IDO1 expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in kynurenine production using L-tryptop... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01968 BindingDB Entry DOI: 10.7270/Q2G164NR |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50300305
(4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2...)Show InChI InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391374
(CHEMBL2146496)Show InChI InChI=1S/C7H5ClN4/c8-7-3-5(1-2-9-7)6-4-10-12-11-6/h1-4H,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391366
(CHEMBL2147991)Show InChI InChI=1S/C9H6F3N3/c10-9(11,12)7-3-1-2-6(4-7)8-5-13-15-14-8/h1-5H,(H,13,14,15) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 7.4 after 60 mins by HPLC an... |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50126143
(Epacadostat | INCB-024360)Show SMILES NS(=O)(=O)NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O Show InChI InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His-tagged human recombinant IDO1 expressed in Escherichia coli using D-tryptophan as substrate by methylene blue/ascorbate ... |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrs |
J Med Chem 62: 8784-8795 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00942 BindingDB Entry DOI: 10.7270/Q22V2KK8 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute for Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 transfected in HEK293T cells assessed as kynurenine formation using L-Trp as substrate after 7 hrs |
Bioorg Med Chem Lett 26: 4330-3 (2016)
Article DOI: 10.1016/j.bmcl.2016.07.031 BindingDB Entry DOI: 10.7270/Q2J38X2Q |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute for Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of human IDO1 transfected in HEK293T cells assessed as kynurenine formation using L-Trp as substrate after 7 hrs |
Bioorg Med Chem Lett 26: 4330-3 (2016)
Article DOI: 10.1016/j.bmcl.2016.07.031 BindingDB Entry DOI: 10.7270/Q2J38X2Q |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50300305
(4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2...)Show InChI InChI=1S/C9H7ClFN5O2/c10-5-3-4(1-2-6(5)11)13-9(14-17)7-8(12)16-18-15-7/h1-3,17H,(H2,12,16)(H,13,14) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50391363
(CHEMBL2148074)Show InChI InChI=1S/C8H6ClN3O/c9-5-1-2-8(13)6(3-5)7-4-10-12-11-7/h1-4,13H,(H,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human IDO1 expressed in HEK293T cells assessed as reduction in kynurenine production using L-tryptophan as substrate incubated for 7 hr... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c01968 BindingDB Entry DOI: 10.7270/Q2G164NR |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391375
(CHEMBL2147993)Show InChI InChI=1S/C8H6N4O2/c13-12(14)7-3-1-2-6(4-7)8-5-9-11-10-8/h1-5H,(H,9,10,11) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391369
(CHEMBL2148075)Show InChI InChI=1S/C9H8ClN3/c1-6-2-3-7(10)4-8(6)9-5-11-13-12-9/h2-5H,1H3,(H,11,12,13) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391361
(CHEMBL2147996)Show InChI InChI=1S/C7H5FN4/c8-7-3-5(1-2-9-7)6-4-10-12-11-6/h1-4H,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM17462
(1,2,3-triazole analogue, 18 | 5-(3-methylphenyl)-1...)Show InChI InChI=1S/C9H9N3/c1-7-3-2-4-8(5-7)9-6-10-12-11-9/h2-6H,1H3,(H,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM50391373
(CHEMBL2148076)Show InChI InChI=1S/C8H5Cl2N3/c9-5-1-2-7(10)6(3-5)8-4-11-13-12-8/h1-4H,(H,11,12,13) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Mus musculus) | BDBM17448
(1,2,3-triazole analogue, 4 | 5-phenyl-1H-1,2,3-tri...)Show InChI InChI=1S/C8H7N3/c1-2-4-7(5-3-1)8-6-9-11-10-8/h1-6H,(H,9,10,11) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Ludwig Center for Cancer Research of the University of Lausanne
Curated by ChEMBL
| Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis |
J Med Chem 55: 5270-90 (2012)
Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50500142
(CHEMBL3747530)Show InChI InChI=1S/C14H9Cl2FN2O/c15-8-1-4-14(20)10(5-8)13(7-18)19-9-2-3-12(17)11(16)6-9/h1-6,13,19-20H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <200 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of N-terminal hexa-Histidine tagged human IDO1 expressed in Escherichia coli using L-tryptophan as substrate after 30 mins by HPLC analysi... |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM387561
(N3-(3- Chloro-4- fluorophenyl)- 7-(2- morpholino- ...)Show SMILES Nc1oc2c(nccc2c1Nc1ccc(F)c(Cl)c1)-c1ccnc(c1)N1CCOCC1 Show InChI InChI=1S/C22H19ClFN5O2/c23-16-12-14(1-2-17(16)24)28-20-15-4-6-27-19(21(15)31-22(20)25)13-3-5-26-18(11-13)29-7-9-30-10-8-29/h1-6,11-12,28H,7-10,25H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | <200 | n/a | n/a | n/a | n/a | n/a | n/a |
SIB Swiss Institute of Bioinformatics
Curated by ChEMBL
| Assay Description Inhibition of N-terminal His-tagged human recombinant IDO1 expressed in Escherichia coli using tryptophan as substrate by UV-visible absorption spect... |
J Med Chem 58: 9421-37 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X |
More data for this Ligand-Target Pair | |