Compile Data Set for Download or QSAR

Found 443 hits with Last Name = 'tam' and Initial = 'sw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (GUINEA PIG)	BDBM50037135 ((4aR,7aR,12bS)-3-Cyclopropylmethyl-9-hydroxy-2,3,4...) Show SMILES Oc1cccc2c1O[C@H]1C(=O)CC[C@H]3CN(CC4CC4)CC[C@]213 Show InChI InChI=1S/C19H23NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,18,21H,4-11H2/t13-,18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of guinea pig brain membranes using 0.5 nM of [3H]naloxone as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50019647 (CHEMBL19982 | Naltrexone semicarbazone) Show SMILES NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45 |w:4.3,TLB:24:23:8:28.12.11,17:28:8:23.21.22,9:8:28.12.11:23.21.22| Show InChI InChI=1S/C21H26N4O4/c22-19(27)24-23-13-5-6-21(28)15-9-12-3-4-14(26)17-16(12)20(21,18(13)29-17)7-8-25(15)10-11-1-2-11/h3-4,11,15,18,26,28H,1-2,5-10H2,(H3,22,24,27)/t15?,18-,20?,21+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of guinea pig brain membranes using 0.5 nM of [3H]naloxone as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50037134 ((+)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,...) Show SMILES Oc1cccc2c1O[C@H]1CCC[C@H]3CN(CC4CC4)CC[C@]213 Show InChI InChI=1S/C19H25NO2/c21-16-5-2-4-15-18(16)22-17-6-1-3-14-12-20(11-13-7-8-13)10-9-19(14,15)17/h2,4-5,13-14,17,21H,1,3,6-12H2/t14-,17-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50367339 (CHEMBL1202433) Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45)C(O)=O |r,w:20.20,TLB:33:44:24:37.38.39,25:24:37.38.39:27.28.44,40:39:24:27.28.44| Show InChI InChI=1S/C36H45N5O7/c1-20(2)16-26(33(44)45)37-32(43)25(17-21-6-4-3-5-7-21)38-34(46)40-39-24-12-13-36(47)28-18-23-10-11-27(42)30-29(23)35(36,31(24)48-30)14-15-41(28)19-22-8-9-22/h3-7,10-11,20,22,25-26,28,31,42,47H,8-9,12-19H2,1-2H3,(H,37,43)(H,44,45)(H2,38,40,46)/t25?,26?,28?,31-,35?,36+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of guinea pig brain membranes using 0.5 nM of [3H]naloxone as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281455 (3-(2-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...) Show SMILES Fc1ccccc1C1=COC2(CCN(CCc3ccccc3)CC2)CC1=O |t:8| Show InChI InChI=1S/C23H24FNO2/c24-21-9-5-4-8-19(21)20-17-27-23(16-22(20)26)11-14-25(15-12-23)13-10-18-6-2-1-3-7-18/h1-9,17H,10-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 221-224 (1993) Article DOI: 10.1016/S0960-894X(01)80880-5 BindingDB Entry DOI: 10.7270/Q2571BX6
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283327 (1-Cyclopropylmethyl-4-[2-(3-phenyl-prop-2-ynyloxy)...) Show SMILES C(CC1CCN(CC2CC2)CC1)OCC#Cc1ccccc1 Show InChI InChI=1S/C20H27NO/c1-2-5-18(6-3-1)7-4-15-22-16-12-19-10-13-21(14-11-19)17-20-8-9-20/h1-3,5-6,19-20H,8-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards sigma receptor using [3H]-(+)-SKF-10,047 as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281406 (8-Benzyl-2-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4...) Show SMILES O=C1C=C(OC11CCN(Cc2ccccc2)CC1)c1ccccc1 |c:2| Show InChI InChI=1S/C21H21NO2/c23-20-15-19(18-9-5-2-6-10-18)24-21(20)11-13-22(14-12-21)16-17-7-3-1-4-8-17/h1-10,15H,11-14,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281423 (8-Phenethyl-2-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-e...) Show SMILES O=C1C=C(OC11CCN(CCc2ccccc2)CC1)c1ccccc1 |c:2| Show InChI InChI=1S/C22H23NO2/c24-21-17-20(19-9-5-2-6-10-19)25-22(21)12-15-23(16-13-22)14-11-18-7-3-1-4-8-18/h1-10,17H,11-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281418 (8-Cyclohexylmethyl-3-phenyl-1-oxa-8-aza-spiro[4.5]...) Show SMILES O=C1C(=COC11CCN(CC2CCCCC2)CC1)c1ccccc1 |c:2| Show InChI InChI=1S/C21H27NO2/c23-20-19(18-9-5-2-6-10-18)16-24-21(20)11-13-22(14-12-21)15-17-7-3-1-4-8-17/h2,5-6,9-10,16-17H,1,3-4,7-8,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000788 ((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...) Show SMILES Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O |r| Show InChI InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50021498 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:49:48:32:53.36.35,THB:9:8:16:4.5.6| Show InChI InChI=1S/C44H54N4O8/c49-29-7-5-25-19-31-43(53)13-11-27(39-41(43,35(25)37(29)55-39)15-17-47(31)21-23-1-2-23)45-33(51)9-10-34(52)46-28-12-14-44(54)32-20-26-6-8-30(50)38-36(26)42(44,40(28)56-38)16-18-48(32)22-24-3-4-24/h5-8,23-24,27-28,31-32,39-40,49-50,53-54H,1-4,9-22H2,(H,45,51)(H,46,52)/t27-,28-,31?,32?,39+,40+,41?,42?,43-,44-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50037134 ((+)-trans-3-Cyclopropylmethyl-2,3,4,4aalpha,5,6,7,...) Show SMILES Oc1cccc2c1O[C@H]1CCC[C@H]3CN(CC4CC4)CC[C@]213 Show InChI InChI=1S/C19H25NO2/c21-16-5-2-4-15-18(16)22-17-6-1-3-14-12-20(11-13-7-8-13)10-9-19(14,15)17/h2,4-5,13-14,17,21H,1,3,6-12H2/t14-,17-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against kappa opioid receptor was measured by using labeled ligand [3H]-ethylketocyclazocine (1 nM) with 500 nM DADLE and 20...				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50037131 ((4aR,7S,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6...) Show SMILES O[C@H]1CC[C@H]2CN(CC3CC3)CC[C@]22[C@H]1Oc1c2cccc1O Show InChI InChI=1S/C19H25NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,16,18,21-22H,4-11H2/t13-,16-,18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50021500 (1N-[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,1...) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(C)=O)ccc3O |r,THB:10:9:4.5.6:17| Show InChI InChI=1S/C22H28N2O4/c1-12(25)23-15-6-7-22(27)17-10-14-4-5-16(26)19-18(14)21(22,20(15)28-19)8-9-24(17)11-13-2-3-13/h4-5,13,15,17,20,26-27H,2-3,6-11H2,1H3,(H,23,25)/t15-,17-,20+,21+,22-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50021495 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:65:64:48:69.52.51,THB:9:8:16:4.5.6| Show InChI InChI=1S/C52H66N8O12/c61-33-7-5-29-19-35-51(69)13-11-31(47-49(51,43(29)45(33)71-47)15-17-59(35)25-27-1-2-27)57-41(67)23-55-39(65)21-53-37(63)9-10-38(64)54-22-40(66)56-24-42(68)58-32-12-14-52(70)36-20-30-6-8-34(62)46-44(30)50(52,48(32)72-46)16-18-60(36)26-28-3-4-28/h5-8,27-28,31-32,35-36,47-48,61-62,69-70H,1-4,9-26H2,(H,53,63)(H,54,64)(H,55,65)(H,56,66)(H,57,67)(H,58,68)/t31-,32-,35?,36?,47+,48+,49?,50?,51-,52-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000784 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(7-pyrrolidin-1...) Show SMILES CN([C@H]1CCC2(C[C@@H]1N1CCCC1)OCCO2)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H28Cl2N2O3/c1-24(20(26)13-15-4-5-16(22)17(23)12-15)18-6-7-21(27-10-11-28-21)14-19(18)25-8-2-3-9-25/h4-5,12,18-19H,2-3,6-11,13-14H2,1H3/t18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa from guinea pig brain membranes using [3H]ethylketocyclazocine as radioligand				J Med Chem 35: 2243-7 (1992) BindingDB Entry DOI: 10.7270/Q20K296N
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50021493 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:73:72:56:77.60.59,THB:9:8:16:4.5.6| Show InChI InChI=1S/C56H72N10O14/c67-35-7-5-31-19-37-55(77)13-11-33(51-53(55,47(31)49(35)79-51)15-17-65(37)27-29-1-2-29)63-45(75)25-61-43(73)23-59-41(71)21-57-39(69)9-10-40(70)58-22-42(72)60-24-44(74)62-26-46(76)64-34-12-14-56(78)38-20-32-6-8-36(68)50-48(32)54(56,52(34)80-50)16-18-66(38)28-30-3-4-30/h5-8,29-30,33-34,37-38,51-52,67-68,77-78H,1-4,9-28H2,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,75)(H,64,76)/t33-,34-,37?,38?,51+,52+,53?,54?,55-,56-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50037135 ((4aR,7aR,12bS)-3-Cyclopropylmethyl-9-hydroxy-2,3,4...) Show SMILES Oc1cccc2c1O[C@H]1C(=O)CC[C@H]3CN(CC4CC4)CC[C@]213 Show InChI InChI=1S/C19H23NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,18,21H,4-11H2/t13-,18-,19-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against kappa opioid receptor was measured by using labeled ligand [3H]-ethylketocyclazocine (1 nM) with 500 nM DADLE and 20...				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50021498 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:49:48:32:53.36.35,THB:9:8:16:4.5.6| Show InChI InChI=1S/C44H54N4O8/c49-29-7-5-25-19-31-43(53)13-11-27(39-41(43,35(25)37(29)55-39)15-17-47(31)21-23-1-2-23)45-33(51)9-10-34(52)46-28-12-14-44(54)32-20-26-6-8-30(50)38-36(26)42(44,40(28)56-38)16-18-48(32)22-24-3-4-24/h5-8,23-24,27-28,31-32,39-40,49-50,53-54H,1-4,9-22H2,(H,45,51)(H,46,52)/t27-,28-,31?,32?,39+,40+,41?,42?,43-,44-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283336 (4-{2-[3-(4-Fluoro-phenyl)-prop-2-ynyloxy]-ethyl}-1...) Show SMILES Fc1ccc(cc1)C#CCOCCC1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H28FNO/c25-24-10-8-22(9-11-24)7-4-19-27-20-15-23-13-17-26(18-14-23)16-12-21-5-2-1-3-6-21/h1-3,5-6,8-11,23H,12-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards sigma receptor using [3H]-(+)-SKF-10,047 as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074349 ((2-Bromo-4-isopropyl-phenyl)-ethyl-[4-(1-ethyl-pro...) Show SMILES CCC(CC)c1cc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H30BrN3/c1-7-16(8-2)19-12-15(6)23-21(24-19)25(9-3)20-11-10-17(14(4)5)13-18(20)22/h10-14,16H,7-9H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281417 (8-Cyclohexylmethyl-3-(4-fluoro-phenyl)-1-oxa-8-aza...) Show SMILES Fc1ccc(cc1)C1=COC2(CCN(CC3CCCCC3)CC2)C1=O |t:8| Show InChI InChI=1S/C21H26FNO2/c22-18-8-6-17(7-9-18)19-15-25-21(20(19)24)10-12-23(13-11-21)14-16-4-2-1-3-5-16/h6-9,15-16H,1-5,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50367336 (CHEMBL1202429 | CHEMBL3144356) Show SMILES Cl.[H][C@@]12[#8]-c3c4c(-[#6][C@@]5([H])[#7](-[#6]-[#6]-6-[#6]-[#6]-6)-[#6]-[#6][C@@]14[C@@]5([#8])[#6]-[#6]\[#6]2=[#7]\[#7]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#6]-[#6])-[#6](=O)-[#8]-[#6])ccc3-[#8] |r,THB:11:10:18:7.6.5| Show InChI InChI=1S/C55H82N14O10/c1-6-31(4)43(50(75)78-5)66-47(72)37(15-11-24-61-52(58)59)62-46(71)36(14-10-23-60-51(56)57)63-48(73)38(26-30(2)3)64-49(74)39(27-32-12-8-7-9-13-32)65-53(76)68-67-35-20-21-55(77)41-28-34-18-19-40(70)44-42(34)54(55,45(35)79-44)22-25-69(41)29-33-16-17-33/h7-9,12-13,18-19,30-31,33,36-39,41,43,45,70,77H,6,10-11,14-17,20-29H2,1-5H3,(H,62,71)(H,63,73)(H,64,74)(H,66,72)(H4,56,57,60)(H4,58,59,61)(H2,65,68,76)/t31?,36?,37?,38?,39?,41?,43?,45-,54?,55+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of guinea pig brain membranes using 1 nM of (-)-[3H]ethylketazocine as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50037135 ((4aR,7aR,12bS)-3-Cyclopropylmethyl-9-hydroxy-2,3,4...) Show SMILES Oc1cccc2c1O[C@H]1C(=O)CC[C@H]3CN(CC4CC4)CC[C@]213 Show InChI InChI=1S/C19H23NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,18,21H,4-11H2/t13-,18-,19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against delta Opioid receptor was measured by using labeled ligand [3H]-DADLE (1 nM) with 4 nM sufentanil				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50367336 (CHEMBL1202429 | CHEMBL3144356) Show SMILES Cl.[H][C@@]12[#8]-c3c4c(-[#6][C@@]5([H])[#7](-[#6]-[#6]-6-[#6]-[#6]-6)-[#6]-[#6][C@@]14[C@@]5([#8])[#6]-[#6]\[#6]2=[#7]\[#7]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#6]-[#6])-[#6](=O)-[#8]-[#6])ccc3-[#8] |r,THB:11:10:18:7.6.5| Show InChI InChI=1S/C55H82N14O10/c1-6-31(4)43(50(75)78-5)66-47(72)37(15-11-24-61-52(58)59)62-46(71)36(14-10-23-60-51(56)57)63-48(73)38(26-30(2)3)64-49(74)39(27-32-12-8-7-9-13-32)65-53(76)68-67-35-20-21-55(77)41-28-34-18-19-40(70)44-42(34)54(55,45(35)79-44)22-25-69(41)29-33-16-17-33/h7-9,12-13,18-19,30-31,33,36-39,41,43,45,70,77H,6,10-11,14-17,20-29H2,1-5H3,(H,62,71)(H,63,73)(H,64,74)(H,66,72)(H4,56,57,60)(H4,58,59,61)(H2,65,68,76)/t31?,36?,37?,38?,39?,41?,43?,45-,54?,55+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor mu 1 of guinea pig brain membranes using 0.5 nM of [3H]naloxone as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50021499 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:57:56:40:61.44.43,THB:9:8:16:4.5.6| Show InChI InChI=1S/C48H60N6O10/c55-31-7-5-27-19-33-47(61)13-11-29(43-45(47,39(27)41(31)63-43)15-17-53(33)23-25-1-2-25)51-37(59)21-49-35(57)9-10-36(58)50-22-38(60)52-30-12-14-48(62)34-20-28-6-8-32(56)42-40(28)46(48,44(30)64-42)16-18-54(34)24-26-3-4-26/h5-8,25-26,29-30,33-34,43-44,55-56,61-62H,1-4,9-24H2,(H,49,57)(H,50,58)(H,51,59)(H,52,60)/t29-,30-,33?,34?,43+,44+,45?,46?,47-,48-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50021495 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:65:64:48:69.52.51,THB:9:8:16:4.5.6| Show InChI InChI=1S/C52H66N8O12/c61-33-7-5-29-19-35-51(69)13-11-31(47-49(51,43(29)45(33)71-47)15-17-59(35)25-27-1-2-27)57-41(67)23-55-39(65)21-53-37(63)9-10-38(64)54-22-40(66)56-24-42(68)58-32-12-14-52(70)36-20-30-6-8-34(62)46-44(30)50(52,48(32)72-46)16-18-60(36)26-28-3-4-28/h5-8,27-28,31-32,35-36,47-48,61-62,69-70H,1-4,9-26H2,(H,53,63)(H,54,64)(H,55,65)(H,56,66)(H,57,67)(H,58,68)/t31-,32-,35?,36?,47+,48+,49?,50?,51-,52-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50021499 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:57:56:40:61.44.43,THB:9:8:16:4.5.6| Show InChI InChI=1S/C48H60N6O10/c55-31-7-5-27-19-33-47(61)13-11-29(43-45(47,39(27)41(31)63-43)15-17-53(33)23-25-1-2-25)51-37(59)21-49-35(57)9-10-36(58)50-22-38(60)52-30-12-14-48(62)34-20-28-6-8-32(56)42-40(28)46(48,44(30)64-42)16-18-54(34)24-26-3-4-26/h5-8,25-26,29-30,33-34,43-44,55-56,61-62H,1-4,9-24H2,(H,49,57)(H,50,58)(H,51,59)(H,52,60)/t29-,30-,33?,34?,43+,44+,45?,46?,47-,48-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50021493 (1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...) Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:73:72:56:77.60.59,THB:9:8:16:4.5.6| Show InChI InChI=1S/C56H72N10O14/c67-35-7-5-31-19-37-55(77)13-11-33(51-53(55,47(31)49(35)79-51)15-17-65(37)27-29-1-2-29)63-45(75)25-61-43(73)23-59-41(71)21-57-39(69)9-10-40(70)58-22-42(72)60-24-44(74)62-26-46(76)64-34-12-14-56(78)38-20-32-6-8-36(68)50-48(32)54(56,52(34)80-50)16-18-66(38)28-30-3-4-30/h5-8,29-30,33-34,37-38,51-52,67-68,77-78H,1-4,9-28H2,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,75)(H,64,76)/t33-,34-,37?,38?,51+,52+,53?,54?,55-,56-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane				J Med Chem 29: 1855-61 (1986) BindingDB Entry DOI: 10.7270/Q21Z43DQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50019647 (CHEMBL19982 | Naltrexone semicarbazone) Show SMILES NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45 |w:4.3,TLB:24:23:8:28.12.11,17:28:8:23.21.22,9:8:28.12.11:23.21.22| Show InChI InChI=1S/C21H26N4O4/c22-19(27)24-23-13-5-6-21(28)15-9-12-3-4-14(26)17-16(12)20(21,18(13)29-17)7-8-25(15)10-11-1-2-11/h3-4,11,15,18,26,28H,1-2,5-10H2,(H3,22,24,27)/t15?,18-,20?,21+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of guinea pig brain membranes using 1 nM of (-)-[3H]ethylketazocine as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50367339 (CHEMBL1202433) Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45)C(O)=O |r,w:20.20,TLB:33:44:24:37.38.39,25:24:37.38.39:27.28.44,40:39:24:27.28.44| Show InChI InChI=1S/C36H45N5O7/c1-20(2)16-26(33(44)45)37-32(43)25(17-21-6-4-3-5-7-21)38-34(46)40-39-24-12-13-36(47)28-18-23-10-11-27(42)30-29(23)35(36,31(24)48-30)14-15-41(28)19-22-8-9-22/h3-7,10-11,20,22,25-26,28,31,42,47H,8-9,12-19H2,1-2H3,(H,37,43)(H,44,45)(H2,38,40,46)/t25?,26?,28?,31-,35?,36+/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor kappa 1 of guinea pig brain membranes using 1 nM of (-)-[3H]ethylketazocine as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074354 (CHEMBL168131 | N,N-Diallyl-N'-(2-bromo-4-dimethyla...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(cc1Br)N(C)C Show InChI InChI=1S/C20H27BrN6/c1-7-12-26(13-8-2)19-22-15(4)23-20(24-19)27(9-3)18-11-10-16(25(5)6)14-17(18)21/h7-8,10-11,14H,1-2,9,12-13H2,3-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281438 (8-(4-Fluoro-benzyl)-3-phenyl-1-oxa-8-aza-spiro[4.5...) Show SMILES Fc1ccc(CN2CCC3(CC2)OC=C(C3=O)c2ccccc2)cc1 |c:14| Show InChI InChI=1S/C21H20FNO2/c22-18-8-6-16(7-9-18)14-23-12-10-21(11-13-23)20(24)19(15-25-21)17-4-2-1-3-5-17/h1-9,15H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50367339 (CHEMBL1202433) Show SMILES CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45)C(O)=O |r,w:20.20,TLB:33:44:24:37.38.39,25:24:37.38.39:27.28.44,40:39:24:27.28.44| Show InChI InChI=1S/C36H45N5O7/c1-20(2)16-26(33(44)45)37-32(43)25(17-21-6-4-3-5-7-21)38-34(46)40-39-24-12-13-36(47)28-18-23-10-11-27(42)30-29(23)35(36,31(24)48-30)14-15-41(28)19-22-8-9-22/h3-7,10-11,20,22,25-26,28,31,42,47H,8-9,12-19H2,1-2H3,(H,37,43)(H,44,45)(H2,38,40,46)/t25?,26?,28?,31-,35?,36+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 of guinea pig brain membranes using 1 nM of [3H]DADLE as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM224024 (BDBM50241435 | Dynorphin A (1-13) | YGGFLRRXRPKLK) Show SMILES [#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#8])=O Show InChI InChI=1S/C75H126N24O15/c1-7-45(6)61(70(111)94-53(25-17-35-87-75(83)84)71(112)99-36-18-26-58(99)69(110)93-50(21-11-13-31-76)64(105)96-56(38-44(4)5)67(108)95-54(72(113)114)22-12-14-32-77)98-65(106)52(24-16-34-86-74(81)82)91-63(104)51(23-15-33-85-73(79)80)92-66(107)55(37-43(2)3)97-68(109)57(40-46-19-9-8-10-20-46)90-60(102)42-88-59(101)41-89-62(103)49(78)39-47-27-29-48(100)30-28-47/h8-10,19-20,27-30,43-45,49-58,61,100H,7,11-18,21-26,31-42,76-78H2,1-6H3,(H,88,101)(H,89,103)(H,90,102)(H,91,104)(H,92,107)(H,93,110)(H,94,111)(H,95,108)(H,96,105)(H,97,109)(H,98,106)(H,113,114)(H4,79,80,85)(H4,81,82,86)(H4,83,84,87)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,61-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Case Western Reserve University Curated by ChEMBL					Assay Description The compound was tested for binding activity towards opioid receptor kappa in guinea pig brain membranes.				J Med Chem 34: 2816-21 (1991) BindingDB Entry DOI: 10.7270/Q2J965CZ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50019647 (CHEMBL19982 | Naltrexone semicarbazone) Show SMILES NC(=O)NN=C1CC[C@@]2(O)C3Cc4ccc(O)c5O[C@@H]1C2(CCN3CC1CC1)c45 |w:4.3,TLB:24:23:8:28.12.11,17:28:8:23.21.22,9:8:28.12.11:23.21.22| Show InChI InChI=1S/C21H26N4O4/c22-19(27)24-23-13-5-6-21(28)15-9-12-3-4-14(26)17-16(12)20(21,18(13)29-17)7-8-25(15)10-11-1-2-11/h3-4,11,15,18,26,28H,1-2,5-10H2,(H3,22,24,27)/t15?,18-,20?,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against Opioid receptor delta 1 of guinea pig brain membranes using 1 nM of [3H]DADLE as radioligand				J Med Chem 29: 1222-5 (1987) BindingDB Entry DOI: 10.7270/Q2M04606
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50037130 ((4aS,7R,7aR,12bS)-3-Cyclopropylmethyl-2,3,4,4a,5,6...) Show SMILES O[C@@H]1CC[C@@H]2CN(CC3CC3)CC[C@]22[C@H]1Oc1c2cccc1O Show InChI InChI=1S/C19H25NO3/c21-15-3-1-2-14-17(15)23-18-16(22)7-6-13-11-20(10-12-4-5-12)9-8-19(13,14)18/h1-3,12-13,16,18,21-22H,4-11H2/t13-,16-,18+,19+/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)				J Med Chem 37: 3121-7 (1994) BindingDB Entry DOI: 10.7270/Q2PK0F6R
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281428 (8-(4-Fluoro-benzyl)-3-(4-fluoro-phenyl)-1-oxa-8-az...) Show SMILES Fc1ccc(CN2CCC3(CC2)OC=C(C3=O)c2ccc(F)cc2)cc1 |c:14| Show InChI InChI=1S/C21H19F2NO2/c22-17-5-1-15(2-6-17)13-24-11-9-21(10-12-24)20(25)19(14-26-21)16-3-7-18(23)8-4-16/h1-8,14H,9-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074332 (CHEMBL167463 | N,N-Diallyl-N'-(2-bromo-4-trifluoro...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(OC(F)(F)F)cc1Br Show InChI InChI=1S/C19H21BrF3N5O/c1-5-10-27(11-6-2)17-24-13(4)25-18(26-17)28(7-3)16-9-8-14(12-15(16)20)29-19(21,22)23/h5-6,8-9,12H,1-2,7,10-11H2,3-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281411 (8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...) Show SMILES Fc1ccc(cc1)C1COC2(CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C21H22FNO2/c22-18-8-6-17(7-9-18)19-15-25-21(20(19)24)10-12-23(13-11-21)14-16-4-2-1-3-5-16/h1-9,19H,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 221-224 (1993) Article DOI: 10.1016/S0960-894X(01)80880-5 BindingDB Entry DOI: 10.7270/Q2571BX6
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281459 (9-Benzyl-3-phenyl-1-oxa-9-aza-spiro[5.5]undec-2-en...) Show SMILES O=C1CC2(CCN(Cc3ccccc3)CC2)OC=C1c1ccccc1 |c:19| Show InChI InChI=1S/C22H23NO2/c24-21-15-22(25-17-20(21)19-9-5-2-6-10-19)11-13-23(14-12-22)16-18-7-3-1-4-8-18/h1-10,17H,11-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor using [3H]-(+)-SKF- 10,047				Bioorg Med Chem Lett 3: 221-224 (1993) Article DOI: 10.1016/S0960-894X(01)80880-5 BindingDB Entry DOI: 10.7270/Q2571BX6
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283320 (1-Phenethyl-4-(3-phenyl-prop-2-ynyloxy)-piperidine...) Show SMILES C(Cc1ccccc1)N1CCC(CC1)OCC#Cc1ccccc1 Show InChI InChI=1S/C22H25NO/c1-3-8-20(9-4-1)12-7-19-24-22-14-17-23(18-15-22)16-13-21-10-5-2-6-11-21/h1-6,8-11,22H,13-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards sigma receptor using [3H]-(+)-SKF-10,047 as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50283329 (1-Benzyl-4-(3-phenyl-prop-2-ynyloxymethyl)-piperid...) Show SMILES C(OCC1CCN(Cc2ccccc2)CC1)C#Cc1ccccc1 Show InChI InChI=1S/C22H25NO/c1-3-8-20(9-4-1)12-7-17-24-19-22-13-15-23(16-14-22)18-21-10-5-2-6-11-21/h1-6,8-11,22H,13-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity towards sigma receptor using [3H]-(+)-SKF-10,047 as radioligand				Bioorg Med Chem Lett 4: 2347-2352 (1994) Article DOI: 10.1016/0960-894X(94)85038-0 BindingDB Entry DOI: 10.7270/Q2S75G8F
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074404 (CHEMBL168844 | N-(2-Bromo-4-isopropyl-phenyl)-N-et...) Show SMILES CCCN(CCC)c1nc(C)nc(n1)N(CC)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H32BrN5/c1-7-12-26(13-8-2)20-23-16(6)24-21(25-20)27(9-3)19-11-10-17(15(4)5)14-18(19)22/h10-11,14-15H,7-9,12-13H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM50074391 (CHEMBL424555 | N,N-Diallyl-N'-(2-bromo-4-isopropyl...) Show SMILES CCN(c1nc(C)nc(n1)N(CC=C)CC=C)c1ccc(cc1Br)C(C)C Show InChI InChI=1S/C21H28BrN5/c1-7-12-26(13-8-2)20-23-16(6)24-21(25-20)27(9-3)19-11-10-17(15(4)5)14-18(19)22/h7-8,10-11,14-15H,1-2,9,12-13H2,3-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity for human recombinant corticotropin releasing factor receptor 1				J Med Chem 42: 805-18 (1999) Article DOI: 10.1021/jm980222w BindingDB Entry DOI: 10.7270/Q29S1Q63
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281411 (8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...) Show SMILES Fc1ccc(cc1)C1COC2(CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C21H22FNO2/c22-18-8-6-17(7-9-18)19-15-25-21(20(19)24)10-12-23(13-11-21)14-16-4-2-1-3-5-16/h1-9,19H,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281414 (8-Benzyl-3-(4-fluoro-phenyl)-1-oxa-8-aza-spiro[4.5...) Show SMILES Fc1ccc(cc1)C1=COC2(CCN(Cc3ccccc3)CC2)C1=O |t:8| Show InChI InChI=1S/C21H20FNO2/c22-18-8-6-17(7-9-18)19-15-25-21(20(19)24)10-12-23(13-11-21)14-16-4-2-1-3-5-16/h1-9,15H,10-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281433 (8-Benzyl-3-phenyl-1-oxa-8-aza-spiro[4.5]dec-2-en-4...) Show SMILES O=C1C(=COC11CCN(Cc2ccccc2)CC1)c1ccccc1 |c:2| Show InChI InChI=1S/C21H21NO2/c23-20-19(18-9-5-2-6-10-18)16-24-21(20)11-13-22(14-12-21)15-17-7-3-1-4-8-17/h1-10,16H,11-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity for sigma receptor in guinea pig brain membrane using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 215-220 (1993) Article DOI: 10.1016/S0960-894X(01)80879-9 BindingDB Entry DOI: 10.7270/Q29023QT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50281447 (3-(4-Fluoro-phenyl)-9-phenethyl-1-oxa-9-aza-spiro[...) Show SMILES Fc1ccc(cc1)C1COC2(CCN(CCc3ccccc3)CC2)CC1=O Show InChI InChI=1S/C23H26FNO2/c24-20-8-6-19(7-9-20)21-17-27-23(16-22(21)26)11-14-25(15-12-23)13-10-18-4-2-1-3-5-18/h1-9,21H,10-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor using radiolabeled ligand [3H]-(+)-SKF- 10,047 was determined				Bioorg Med Chem Lett 3: 221-224 (1993) Article DOI: 10.1016/S0960-894X(01)80880-5 BindingDB Entry DOI: 10.7270/Q2571BX6
					More data for this Ligand-Target Pair

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