Compile Data Set for Download or QSAR

Found 246 hits with Last Name = 'knöpfel' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004899 ((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@H]1C[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004899 ((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@H]1C[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50004899 ((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@H]1C[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) Show SMILES N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O Show InChI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004899 ((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@H]1C[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50004863 ((+/-)-trans-ACPD | (1S,3S)-1-Amino-cyclopentane-1,...) Show SMILES N[C@]1(CC[C@@H](C1)C(O)=O)C(O)=O Show InChI InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50004899 ((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@H]1C[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNS Research Curated by PDSP Ki Database									J Neurochem 67: 58-63 (1996) Article DOI: 10.1046/j.1471-4159.1996.67010058.x BindingDB Entry DOI: 10.7270/Q2P55M1B
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209374 (US9266883, 240) Show SMILES CC(C)Sc1cc(NC(=O)N2CCCc3cc(CN(C)C(C)=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C23H26N6O3S/c1-14(2)33-20-9-21(25-11-18(20)10-24)27-23(32)29-7-5-6-16-8-17(12-28(4)15(3)31)19(13-30)26-22(16)29/h8-9,11,13-14H,5-7,12H2,1-4H3,(H,25,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209350 (US9266883, 149) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCSCC4=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C24H27N7O4S/c1-35-7-4-26-19-10-21(27-12-18(19)11-25)29-24(34)31-5-2-3-16-9-17(20(14-32)28-23(16)31)13-30-6-8-36-15-22(30)33/h9-10,12,14H,2-8,13,15H2,1H3,(H2,26,27,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.100	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209388 (US9266883, 263) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(N4CCOC4=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C22H23N7O5/c1-33-7-4-24-16-10-19(25-12-15(16)11-23)27-21(31)29-5-2-3-14-9-18(17(13-30)26-20(14)29)28-6-8-34-22(28)32/h9-10,12-13H,2-8H2,1H3,(H2,24,25,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209258 (US9266883, 16) Show SMILES CC(C)S(=O)(=O)c1ccccc1Nc1nc(NC(=O)N2CCCc3ccc(C=O)nc23)ncc1Cl Show InChI InChI=1S/C23H23ClN6O4S/c1-14(2)35(33,34)19-8-4-3-7-18(19)27-20-17(24)12-25-22(28-20)29-23(32)30-11-5-6-15-9-10-16(13-31)26-21(15)30/h3-4,7-10,12-14H,5-6,11H2,1-2H3,(H2,25,27,28,29,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209340 (US9266883, 115) Show SMILES COC[C@@H](C)Oc1cc(NC(=O)N2CCCc3cc(CN4[C@@H](C)COC4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C25H28N6O6/c1-15-13-36-25(34)31(15)11-18-7-17-5-4-6-30(23(17)28-20(18)12-32)24(33)29-22-8-21(19(9-26)10-27-22)37-16(2)14-35-3/h7-8,10,12,15-16H,4-6,11,13-14H2,1-3H3,(H,27,29,33)/t15-,16+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209277 (US9266883, 35) Show SMILES O=Cc1ccc2CCCN(C(=O)Nc3cc(OCC4CCO4)c(cn3)C#N)c2n1 Show InChI InChI=1S/C20H19N5O4/c21-9-14-10-22-18(8-17(14)29-12-16-5-7-28-16)24-20(27)25-6-1-2-13-3-4-15(11-26)23-19(13)25/h3-4,8,10-11,16H,1-2,5-7,12H2,(H,22,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209349 (US9266883, 148) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN(C)C(=O)COC)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C24H29N7O5/c1-30(22(33)15-36-3)13-17-9-16-5-4-7-31(23(16)28-20(17)14-32)24(34)29-21-10-19(26-6-8-35-2)18(11-25)12-27-21/h9-10,12,14H,4-8,13,15H2,1-3H3,(H2,26,27,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209342 (US9266883, 120) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4[C@@H](C)COCC4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C25H29N7O5/c1-16-14-37-15-23(34)32(16)12-18-8-17-4-3-6-31(24(17)29-21(18)13-33)25(35)30-22-9-20(27-5-7-36-2)19(10-26)11-28-22/h8-9,11,13,16H,3-7,12,14-15H2,1-2H3,(H2,27,28,30,35)/t16-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209345 (US9266883, 141) Show SMILES CC(C)Oc1cc(NC(=O)N2CCCc3cc(CN(C)C(=O)CO)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C23H26N6O5/c1-14(2)34-19-8-20(25-10-17(19)9-24)27-23(33)29-6-4-5-15-7-16(11-28(3)21(32)13-31)18(12-30)26-22(15)29/h7-8,10,12,14,31H,4-6,11,13H2,1-3H3,(H,25,27,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209334 (US9266883, 98) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCOCC4=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C24H27N7O5/c1-35-7-4-26-19-10-21(27-12-18(19)11-25)29-24(34)31-5-2-3-16-9-17(20(14-32)28-23(16)31)13-30-6-8-36-15-22(30)33/h9-10,12,14H,2-8,13,15H2,1H3,(H2,26,27,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209354 (US9266883, 188) Show SMILES CN(Cc1cc2CCCN(C(=O)Nc3cc(NCCOC(F)(F)F)c(cn3)C#N)c2nc1C=O)C(C)=O Show InChI InChI=1S/C23H24F3N7O4/c1-14(35)32(2)12-16-8-15-4-3-6-33(21(15)30-19(16)13-34)22(36)31-20-9-18(17(10-27)11-29-20)28-5-7-37-23(24,25)26/h8-9,11,13H,3-7,12H2,1-2H3,(H2,28,29,31,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209348 (US9266883, 145) Show SMILES CC(C)Oc1cc(NC(=O)N2CCCc3cc(CN(C)C(=O)CN(C)C)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C25H31N7O4/c1-16(2)36-21-10-22(27-12-19(21)11-26)29-25(35)32-8-6-7-17-9-18(20(15-33)28-24(17)32)13-31(5)23(34)14-30(3)4/h9-10,12,15-16H,6-8,13-14H2,1-5H3,(H,27,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209368 (US9266883, 228) Show SMILES COCCNc1cc(NC(=O)N2[C@@H](C)CCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C26H32N8O4/c1-17-4-5-18-10-19(14-33-8-7-32(2)15-24(33)36)22(16-35)30-25(18)34(17)26(37)31-23-11-21(28-6-9-38-3)20(12-27)13-29-23/h10-11,13,16-17H,4-9,14-15H2,1-3H3,(H2,28,29,31,37)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209341 (US9266883, 118) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4[C@H](C)COCC4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C25H29N7O5/c1-16-14-37-15-23(34)32(16)12-18-8-17-4-3-6-31(24(17)29-21(18)13-33)25(35)30-22-9-20(27-5-7-36-2)19(10-26)11-28-22/h8-9,11,13,16H,3-7,12,14-15H2,1-2H3,(H2,27,28,30,35)/t16-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209361 (US9266883, 205) Show SMILES COC[C@@H](C)Oc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C26H31N7O5/c1-17(16-37-3)38-22-10-23(28-12-20(22)11-27)30-26(36)33-6-4-5-18-9-19(21(15-34)29-25(18)33)13-32-8-7-31(2)14-24(32)35/h9-10,12,15,17H,4-8,13-14,16H2,1-3H3,(H,28,30,36)/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209367 (US9266883, 227) Show SMILES CC(C)Oc1cc(NC(=O)N2[C@@H](C)CCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C26H31N7O4/c1-16(2)37-22-10-23(28-12-20(22)11-27)30-26(36)33-17(3)5-6-18-9-19(21(15-34)29-25(18)33)13-32-8-7-31(4)14-24(32)35/h9-10,12,15-17H,5-8,13-14H2,1-4H3,(H,28,30,36)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209333 (US9266883, 95) Show SMILES CC(C)Nc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C25H30N8O3/c1-16(2)28-20-10-22(27-12-19(20)11-26)30-25(36)33-6-4-5-17-9-18(21(15-34)29-24(17)33)13-32-8-7-31(3)14-23(32)35/h9-10,12,15-16H,4-8,13-14H2,1-3H3,(H2,27,28,30,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209275 (US9266883, 33) Show SMILES CC(C)Oc1cc(NC(=O)N2CCCc3ccc(C=O)nc23)ncc1C#N Show InChI InChI=1S/C19H19N5O3/c1-12(2)27-16-8-17(21-10-14(16)9-20)23-19(26)24-7-3-4-13-5-6-15(11-25)22-18(13)24/h5-6,8,10-12H,3-4,7H2,1-2H3,(H,21,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209332 (US9266883, 92) Show SMILES CC(C)Oc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C25H29N7O4/c1-16(2)36-21-10-22(27-12-19(21)11-26)29-25(35)32-6-4-5-17-9-18(20(15-33)28-24(17)32)13-31-8-7-30(3)14-23(31)34/h9-10,12,15-16H,4-8,13-14H2,1-3H3,(H,27,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209282 (US9266883, 40) Show SMILES O=Cc1ccc2CCCN(C(=O)Nc3cc(OC4CCOC4)c(cn3)C#N)c2n1 Show InChI InChI=1S/C20H19N5O4/c21-9-14-10-22-18(8-17(14)29-16-5-7-28-12-16)24-20(27)25-6-1-2-13-3-4-15(11-26)23-19(13)25/h3-4,8,10-11,16H,1-2,5-7,12H2,(H,22,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209307 (US9266883, 65) Show SMILES OC[C@H]1[C@@H]2CC[C@@H](C2)[C@H]1Nc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C25H28N6O4/c26-9-18-10-27-22(8-20(18)28-23-15-4-3-14(6-15)19(23)12-33)30-25(35)31-5-1-2-16-7-17(11-32)21(13-34)29-24(16)31/h7-8,10,13-15,19,23,32-33H,1-6,11-12H2,(H2,27,28,30,35)/t14-,15+,19+,23-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209302 (US9266883, 60) Show SMILES OCc1cc2CCCN(C(=O)Nc3cc(OCC(O)CCCl)c(cn3)C#N)c2nc1C=O Show InChI InChI=1S/C21H22ClN5O5/c22-4-3-16(30)12-32-18-7-19(24-9-15(18)8-23)26-21(31)27-5-1-2-13-6-14(10-28)17(11-29)25-20(13)27/h6-7,9,11,16,28,30H,1-5,10,12H2,(H,24,26,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209337 (US9266883, 105) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CC[C@@H](O)C4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C24H27N7O5/c1-36-8-5-26-18-10-21(27-12-17(18)11-25)29-24(35)31-6-2-3-15-9-16(19(14-32)28-22(15)31)13-30-7-4-20(33)23(30)34/h9-10,12,14,20,33H,2-8,13H2,1H3,(H2,26,27,29,35)/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209335 (US9266883, 100) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CC[C@H](O)C4=O)c(C=O)nc23)ncc1C#N |r| Show InChI InChI=1S/C24H27N7O5/c1-36-8-5-26-18-10-21(27-12-17(18)11-25)29-24(35)31-6-2-3-15-9-16(19(14-32)28-22(15)31)13-30-7-4-20(33)23(30)34/h9-10,12,14,20,33H,2-8,13H2,1H3,(H2,26,27,29,35)/t20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209389 (US9266883, 264) Show SMILES CC(C)Oc1cc(NC(=O)N2CCCc3cc(C4CCOC4)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C23H25N5O4/c1-14(2)32-20-9-21(25-11-17(20)10-24)27-23(30)28-6-3-4-15-8-18(16-5-7-31-13-16)19(12-29)26-22(15)28/h8-9,11-12,14,16H,3-7,13H2,1-2H3,(H,25,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209276 (US9266883, 34) Show SMILES O=Cc1ccc2CCCN(C(=O)Nc3cc(OCC4CCCO4)c(cn3)C#N)c2n1 Show InChI InChI=1S/C21H21N5O4/c22-10-15-11-23-19(9-18(15)30-13-17-4-2-8-29-17)25-21(28)26-7-1-3-14-5-6-16(12-27)24-20(14)26/h5-6,9,11-12,17H,1-4,7-8,13H2,(H,23,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209382 (US9266883, 254) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)-n2ccnc2)ncc1C#N Show InChI InChI=1S/C22H22N8O3/c1-33-8-5-25-17-10-20(26-12-16(17)11-23)28-22(32)30-6-2-3-15-9-19(29-7-4-24-14-29)18(13-31)27-21(15)30/h4,7,9-10,12-14H,2-3,5-6,8H2,1H3,(H2,25,26,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209370 (US9266883, 234) Show SMILES CC(C)Oc1cc(NC(=O)N2CCc3ccc(C=O)nc23)ncc1C#N Show InChI InChI=1S/C18H17N5O3/c1-11(2)26-15-7-16(20-9-13(15)8-19)22-18(25)23-6-5-12-3-4-14(10-24)21-17(12)23/h3-4,7,9-11H,5-6H2,1-2H3,(H,20,22,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209392 (US9266883, 267) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(C4CCN(CC(F)F)CC4)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C26H31F2N7O3/c1-38-10-6-30-21-12-24(31-14-19(21)13-29)33-26(37)35-7-2-3-18-11-20(22(16-36)32-25(18)35)17-4-8-34(9-5-17)15-23(27)28/h11-12,14,16-17,23H,2-10,15H2,1H3,(H2,30,31,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209351 (US9266883, 150) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCS(=O)(=O)CC4=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C24H27N7O6S/c1-37-7-4-26-19-10-21(27-12-18(19)11-25)29-24(34)31-5-2-3-16-9-17(20(14-32)28-23(16)31)13-30-6-8-38(35,36)15-22(30)33/h9-10,12,14H,2-8,13,15H2,1H3,(H2,26,27,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209268 (US9266883, 26) Show SMILES CC1(O)CCN(CC1)c1cc(NC(=O)N2CCCc3ccc(C=O)nc23)ncc1C#N Show InChI InChI=1S/C22H24N6O3/c1-22(31)6-9-27(10-7-22)18-11-19(24-13-16(18)12-23)26-21(30)28-8-2-3-15-4-5-17(14-29)25-20(15)28/h4-5,11,13-14,31H,2-3,6-10H2,1H3,(H,24,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209278 (US9266883, 36) Show SMILES O=Cc1ccc2CCCN(C(=O)Nc3cc(OCC4CCCCO4)c(cn3)C#N)c2n1 Show InChI InChI=1S/C22H23N5O4/c23-11-16-12-24-20(10-19(16)31-14-18-5-1-2-9-30-18)26-22(29)27-8-3-4-15-6-7-17(13-28)25-21(15)27/h6-7,10,12-13,18H,1-5,8-9,14H2,(H,24,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209357 (US9266883, 197 | US9266883, 199) Show SMILES CN1CCN(Cc2cc3CCCN(C(=O)Nc4cc(NCCO)c(cn4)C#N)c3nc2C=O)C(=O)C1 Show InChI InChI=1S/C24H28N8O4/c1-30-6-7-31(22(35)14-30)13-17-9-16-3-2-5-32(23(16)28-20(17)15-34)24(36)29-21-10-19(26-4-8-33)18(11-25)12-27-21/h9-10,12,15,33H,2-8,13-14H2,1H3,(H2,26,27,29,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209265 (US9266883, 23) Show SMILES COCCOc1cc(NC(=O)N2CCCc3ccc(C=O)nc23)ncc1C#N Show InChI InChI=1S/C19H19N5O4/c1-27-7-8-28-16-9-17(21-11-14(16)10-20)23-19(26)24-6-2-3-13-4-5-15(12-25)22-18(13)24/h4-5,9,11-12H,2-3,6-8H2,1H3,(H,21,23,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209339 (US9266883, 110) Show SMILES COCCNc1cc(NC(=O)N2CCCc3cc(CN4CCNCC4=O)c(C=O)nc23)ncc1C#N Show InChI InChI=1S/C24H28N8O4/c1-36-8-5-27-19-10-21(28-12-18(19)11-25)30-24(35)32-6-2-3-16-9-17(20(15-33)29-23(16)32)14-31-7-4-26-13-22(31)34/h9-10,12,15,26H,2-8,13-14H2,1H3,(H2,27,28,30,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 [388-802] (Homo sapiens (Human))	BDBM209298 (US9266883, 56) Show SMILES OCc1cc2CCCN(C(=O)Nc3cc(NC4CCOC4)c(cn3)C#N)c2nc1C=O Show InChI InChI=1S/C21H22N6O4/c22-8-15-9-23-19(7-17(15)24-16-3-5-31-12-16)26-21(30)27-4-1-2-13-6-14(10-28)18(11-29)25-20(13)27/h6-7,9,11,16,28H,1-5,10,12H2,(H2,23,24,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	7.5	30
Novartis AG US Patent					Assay Description Liquid handling and incubation steps were done on an Innovadyne Nanodrop Express equipped with a robotic arm (Thermo CatX, Caliper Twister II) and an...				US Patent US9266883 (2016) BindingDB Entry DOI: 10.7270/Q2CC0ZGP
					More data for this Ligand-Target Pair

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