Compile Data Set for Download or QSAR

Found 72 hits with Last Name = 'abbas' and Initial = 'g'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437932 (CHEMBL2408704) Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1 |w:15.17| Show InChI InChI=1S/C21H19FN4O5S2/c1-3-30-20-17(19(27)16-10-13(22)4-9-18(16)31-20)11-23-14-5-7-15(8-6-14)33(28,29)26-21-25-24-12(2)32-21/h4-11,20,23H,3H2,1-2H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437935 (CHEMBL2408701) Show SMILES Brc1ccc2occ(C3Nc4ccccc4S(=O)(=O)N3)c(=O)c2c1 Show InChI InChI=1S/C16H11BrN2O4S/c17-9-5-6-13-10(7-9)15(20)11(8-23-13)16-18-12-3-1-2-4-14(12)24(21,22)19-16/h1-8,16,18-19H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437937 (CHEMBL2408699) Show SMILES O=c1c(coc2ccccc12)C1Nc2ccccc2S(=O)(=O)N1 Show InChI InChI=1S/C16H12N2O4S/c19-15-10-5-1-3-7-13(10)22-9-11(15)16-17-12-6-2-4-8-14(12)23(20,21)18-16/h1-9,16-18H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437931 (CHEMBL2408705) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1 |w:14.16| Show InChI InChI=1S/C21H20N4O5S2/c1-3-29-20-17(19(26)16-6-4-5-7-18(16)30-20)12-22-14-8-10-15(11-9-14)32(27,28)25-21-24-23-13(2)31-21/h4-12,20,22H,3H2,1-2H3,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437935 (CHEMBL2408701) Show SMILES Brc1ccc2occ(C3Nc4ccccc4S(=O)(=O)N3)c(=O)c2c1 Show InChI InChI=1S/C16H11BrN2O4S/c17-9-5-6-13-10(7-9)15(20)11(8-23-13)16-18-12-3-1-2-4-14(12)24(21,22)19-16/h1-8,16,18-19H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437934 (CHEMBL2408702) Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-12(9-22-14-5-3-4-6-15(14)28(21,24)25)16(23)11-7-10(19)8-13(20)17(11)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM237231 (hCA inhibitor, 1) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18N2O5S/c1-2-24-18-15(17(21)14-5-3-4-6-16(14)25-18)11-20-12-7-9-13(10-8-12)26(19,22)23/h3-11,18,20H,2H2,1H3,(H2,19,22,23)/b15-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	228	-37.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437931 (CHEMBL2408705) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1 |w:14.16| Show InChI InChI=1S/C21H20N4O5S2/c1-3-29-20-17(19(26)16-6-4-5-7-18(16)30-20)12-22-14-8-10-15(11-9-14)32(27,28)25-21-24-23-13(2)31-21/h4-12,20,22H,3H2,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM237234 (hCA inhibitor, 5) Show SMILES CCOC1Oc2c(CC)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C20H22N2O5S/c1-3-13-6-5-7-16-18(23)17(20(26-4-2)27-19(13)16)12-22-14-8-10-15(11-9-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)/b17-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	286	-37.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437933 (CHEMBL2408703) Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C20H22N2O5S/c1-3-13-9-10-17-14(11-13)19(23)15(20(27-17)26-4-2)12-22-16-7-5-6-8-18(16)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437945 (CHEMBL1814393) Show SMILES CCOC1Oc2ccc(Br)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O |w:15.17| Show InChI InChI=1S/C18H17BrN2O5S/c1-2-25-18-15(17(22)14-9-11(19)3-8-16(14)26-18)10-21-12-4-6-13(7-5-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437929 (CHEMBL2408560) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1 |w:14.16| Show InChI InChI=1S/C23H21N3O5S/c1-2-30-23-19(22(27)18-7-3-4-8-20(18)31-23)15-25-16-10-12-17(13-11-16)32(28,29)26-21-9-5-6-14-24-21/h3-15,23,25H,2H2,1H3,(H,24,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM60962 (hCA inhibitor, 2) Show SMILES CCOC1Oc2c(F)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17FN2O5S/c1-2-25-18-14(16(22)13-4-3-5-15(19)17(13)26-18)10-21-11-6-8-12(9-7-11)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)/b14-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	437	-36.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10860 (4-(aminomethyl)benzene-1-sulfonamide | CHEMBL419 |...) Show SMILES NCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C7H10N2O2S/c8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,5,8H2,(H2,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	612	-35.5	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair				3D Structure (docked)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10857 (4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...) Show SMILES Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	628	-35.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair				3D Structure (docked)
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437936 (CHEMBL2408700) Show SMILES Fc1ccc2occ(C3Nc4ccccc4S(=O)(=O)N3)c(=O)c2c1 Show InChI InChI=1S/C16H11FN2O4S/c17-9-5-6-13-10(7-9)15(20)11(8-23-13)16-18-12-3-1-2-4-14(12)24(21,22)19-16/h1-8,16,18-19H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437939 (CHEMBL1814399) Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-14(9-22-11-4-3-5-12(8-11)28(21,24)25)16(23)13-6-10(19)7-15(20)17(13)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM237231 (hCA inhibitor, 1) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18N2O5S/c1-2-24-18-15(17(21)14-5-3-4-6-16(14)25-18)11-20-12-7-9-13(10-8-12)26(19,22)23/h3-11,18,20H,2H2,1H3,(H2,19,22,23)/b15-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	943	-34.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM10860 (4-(aminomethyl)benzene-1-sulfonamide | CHEMBL419 |...) Show SMILES NCc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C7H10N2O2S/c8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,5,8H2,(H2,9,10,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.01E+3	-34.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C6H7NO2S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	1.10E+3	-34.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM237232 (hCA inhibitor, 3) Show SMILES CCOC1Oc2c(Br)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17BrN2O5S/c1-2-25-18-14(16(22)13-4-3-5-15(19)17(13)26-18)10-21-11-6-8-12(9-7-11)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)/b14-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.13E+3	-33.9	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM10857 (4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...) Show SMILES Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.21E+3	-33.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM237234 (hCA inhibitor, 5) Show SMILES CCOC1Oc2c(CC)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C20H22N2O5S/c1-3-13-6-5-7-16-18(23)17(20(26-4-2)27-19(13)16)12-22-14-8-10-15(11-9-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)/b17-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.25E+3	-33.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437946 (CHEMBL1814392) Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O |w:15.17| Show InChI InChI=1S/C18H17FN2O5S/c1-2-25-18-15(17(22)14-9-11(19)3-8-16(14)26-18)10-21-12-4-6-13(7-5-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM60962 (hCA inhibitor, 2) Show SMILES CCOC1Oc2c(F)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17FN2O5S/c1-2-25-18-14(16(22)13-4-3-5-15(19)17(13)26-18)10-21-11-6-8-12(9-7-11)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)/b14-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.53E+3	-33.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM237233 (hCA inhibitor, 4) Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-14(9-22-11-3-5-12(6-4-11)28(21,24)25)16(23)13-7-10(19)8-15(20)17(13)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)/b14-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.86E+3	-32.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437938 (CHEMBL1814400) Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C20H22N2O5S/c1-3-13-8-9-18-16(10-13)19(23)17(20(27-18)26-4-2)12-22-14-6-5-7-15(11-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM237232 (hCA inhibitor, 3) Show SMILES CCOC1Oc2c(Br)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17BrN2O5S/c1-2-25-18-14(16(22)13-4-3-5-15(19)17(13)26-18)10-21-11-6-8-12(9-7-11)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)/b14-10+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.24E+3	-32.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437943 (CHEMBL1814395) Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C20H22N2O5S/c1-3-13-5-10-18-16(11-13)19(23)17(20(27-18)26-4-2)12-22-14-6-8-15(9-7-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM12414 (CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...) Show SMILES NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C6H7NO2S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H2,7,8,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.11E+3	-30.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM237233 (hCA inhibitor, 4) Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-14(9-22-11-3-5-12(6-4-11)28(21,24)25)16(23)13-7-10(19)8-15(20)17(13)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)/b14-9+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.28E+3	-30.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437944 (CHEMBL1814394) Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-14(9-22-11-3-5-12(6-4-11)28(21,24)25)16(23)13-7-10(19)8-15(20)17(13)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437947 (CHEMBL1814391) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(N)(=O)=O |w:14.16| Show InChI InChI=1S/C18H18N2O5S/c1-2-24-18-15(17(21)14-5-3-4-6-16(14)25-18)11-20-12-7-9-13(10-8-12)26(19,22)23/h3-11,18,20H,2H2,1H3,(H2,19,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437928 (CHEMBL2408697) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccc(OC)nn1 |w:14.16| Show InChI InChI=1S/C23H22N4O6S/c1-3-32-23-18(22(28)17-6-4-5-7-19(17)33-23)14-24-15-8-10-16(11-9-15)34(29,30)27-20-12-13-21(31-2)26-25-20/h4-14,23-24H,3H2,1-2H3,(H,25,27)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437927 (CHEMBL2408698) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1cc(OC)nc(OC)n1 |w:14.16| Show InChI InChI=1S/C24H24N4O7S/c1-4-34-23-18(22(29)17-7-5-6-8-19(17)35-23)14-25-15-9-11-16(12-10-15)36(30,31)28-20-13-21(32-2)27-24(26-20)33-3/h5-14,23,25H,4H2,1-3H3,(H,26,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10859 (4-methylbenzene-1-sulfonamide | CHEMBL574 | aromat...) Show SMILES Cc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	8.14E+3	-29.0	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair				3D Structure (docked)
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437940 (CHEMBL1814398) Show SMILES CCOC1Oc2ccc(Br)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O |w:15.17| Show InChI InChI=1S/C18H17BrN2O5S/c1-2-25-18-15(17(22)14-8-11(19)6-7-16(14)26-18)10-21-12-4-3-5-13(9-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437930 (CHEMBL2408706) Show SMILES CCOC1Oc2ccc(Br)cc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1 |w:15.17| Show InChI InChI=1S/C23H20BrN3O5S/c1-2-31-23-19(22(28)18-13-15(24)6-11-20(18)32-23)14-26-16-7-9-17(10-8-16)33(29,30)27-21-5-3-4-12-25-21/h3-14,23,26H,2H2,1H3,(H,25,27)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM237231 (hCA inhibitor, 1) Show SMILES CCOC1Oc2ccccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18N2O5S/c1-2-24-18-15(17(21)14-5-3-4-6-16(14)25-18)11-20-12-7-9-13(10-8-12)26(19,22)23/h3-11,18,20H,2H2,1H3,(H2,19,22,23)/b15-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.37E+4	-27.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437938 (CHEMBL1814400) Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C20H22N2O5S/c1-3-13-8-9-18-16(10-13)19(23)17(20(27-18)26-4-2)12-22-14-6-5-7-15(11-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Intestinal-type alkaline phosphatase (Bos taurus (Cattle))	BDBM50437941 (CHEMBL1814397) Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O |w:15.17| Show InChI InChI=1S/C18H17FN2O5S/c1-2-25-18-15(17(22)14-8-11(19)6-7-16(14)26-18)10-21-12-4-3-5-13(9-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins by spe...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437941 (CHEMBL1814397) Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O |w:15.17| Show InChI InChI=1S/C18H17FN2O5S/c1-2-25-18-15(17(22)14-8-11(19)6-7-16(14)26-18)10-21-12-4-3-5-13(9-12)27(20,23)24/h3-10,18,21H,2H2,1H3,(H2,20,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437932 (CHEMBL2408704) Show SMILES CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1nnc(C)s1 |w:15.17| Show InChI InChI=1S/C21H19FN4O5S2/c1-3-30-20-17(19(27)16-10-13(22)4-9-18(16)31-20)11-23-14-5-7-15(8-6-14)33(28,29)26-21-25-24-12(2)32-21/h4-11,20,23H,3H2,1-2H3,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 6 (Homo sapiens (Human))	BDBM10859 (4-methylbenzene-1-sulfonamide | CHEMBL574 | aromat...) Show SMILES Cc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.12E+4	-26.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437929 (CHEMBL2408560) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1ccccn1 |w:14.16| Show InChI InChI=1S/C23H21N3O5S/c1-2-30-23-19(22(27)18-7-3-4-8-20(18)31-23)15-25-16-10-12-17(13-11-16)32(28,29)26-21-9-5-6-14-24-21/h3-15,23,25H,2H2,1H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437927 (CHEMBL2408698) Show SMILES CCOC1Oc2ccccc2C(=O)C1=CNc1ccc(cc1)S(=O)(=O)Nc1cc(OC)nc(OC)n1 |w:14.16| Show InChI InChI=1S/C24H24N4O7S/c1-4-34-23-18(22(29)17-7-5-6-8-19(17)35-23)14-25-15-9-11-16(12-10-15)36(30,31)28-20-13-21(32-2)27-24(26-20)33-3/h5-14,23,25H,4H2,1-3H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM237234 (hCA inhibitor, 5) Show SMILES CCOC1Oc2c(CC)cccc2C(=O)\C1=C/Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C20H22N2O5S/c1-3-13-6-5-7-16-18(23)17(20(26-4-2)27-19(13)16)12-22-14-8-10-15(11-9-14)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)/b17-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.43E+4	-26.3	n/a	n/a	n/a	n/a	n/a	7.4	25
Ondokuz Mayis University					Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...				J Enzyme Inhib Med Chem 27: 744-7 (2012) Article DOI: 10.3109/14756366.2011.614607 BindingDB Entry DOI: 10.7270/Q2H70DQ2
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437939 (CHEMBL1814399) Show SMILES CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1cccc(c1)S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C18H16Br2N2O5S/c1-2-26-18-14(9-22-11-4-3-5-12(8-11)28(21,24)25)16(23)13-6-10(19)7-15(20)17(13)27-18/h3-9,18,22H,2H2,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437937 (CHEMBL2408699) Show SMILES O=c1c(coc2ccccc12)C1Nc2ccccc2S(=O)(=O)N1 Show InChI InChI=1S/C16H12N2O4S/c19-15-10-5-1-3-7-13(10)22-9-11(15)16-17-12-6-2-4-8-14(12)23(20,21)18-16/h1-9,16-18H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM50437933 (CHEMBL2408703) Show SMILES CCOC1Oc2ccc(CC)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O |w:16.18| Show InChI InChI=1S/C20H22N2O5S/c1-3-13-9-10-17-14(11-13)19(23)15(20(27-17)26-4-2)12-22-16-7-5-6-8-18(16)28(21,24)25/h5-12,20,22H,3-4H2,1-2H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Forman Christian College (A Chartered University) Curated by ChEMBL					Assay Description Inhibition of bovine kidney intestinal alkaline phosphatase using p-NPP as substrate treated 10 mins before substrate addition measured after 30 mins...				Eur J Med Chem 66: 438-49 (2013) Article DOI: 10.1016/j.ejmech.2013.06.015 BindingDB Entry DOI: 10.7270/Q20K29ZH
					More data for this Ligand-Target Pair

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