Compile Data Set for Download or QSAR

Found 89 hits with Last Name = 'beltramo' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334011 (4-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C21H20F3N3O/c22-21(23,24)18-6-2-4-16(12-18)19-13-25-20(26-19)17-5-1-3-15(11-17)14-27-7-9-28-10-8-27/h1-6,11-13H,7-10,14H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human cloned CB2 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334011 (4-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C21H20F3N3O/c22-21(23,24)18-6-2-4-16(12-18)19-13-25-20(26-19)17-5-1-3-15(11-17)14-27-7-9-28-10-8-27/h1-6,11-13H,7-10,14H2,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Displacement of [3H]-CP55940 from human cloned CB1 receptor expressed in CHO cells				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082051 (CHEMBL3422514) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(O)=O |r| Show InChI InChI=1S/C88H128N18O19/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-32-76(113)98-66(87(124)125)41-42-75(112)93-43-24-23-30-64(100-83(120)70(97-55(4)108)48-58-35-39-61(110)40-36-58)81(118)104-71(49-59-51-95-63-29-22-21-28-62(59)63)84(121)105-72(50-74(89)111)85(122)106-73(53-107)86(123)103-69(47-56-26-18-17-19-27-56)79(116)96-52-77(114)99-68(45-54(2)3)82(119)101-65(31-25-44-94-88(91)92)80(117)102-67(78(90)115)46-57-33-37-60(109)38-34-57/h17-19,21-22,26-29,33-40,51,54,64-73,95,107,109-110H,5-16,20,23-25,30-32,41-50,52-53H2,1-4H3,(H2,89,111)(H2,90,115)(H,93,112)(H,96,116)(H,97,108)(H,98,113)(H,99,114)(H,100,120)(H,101,119)(H,102,117)(H,103,123)(H,104,118)(H,105,121)(H,106,122)(H,124,125)(H4,91,92,94)/t64-,65-,66-,67-,68-,69-,70-,71-,72-,73-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082064 (CHEMBL3422515) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(O)=O |r| Show InChI InChI=1S/C81H124N18O20/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-28-69(107)91-58(80(118)119)37-38-68(106)87-39-22-21-26-56(93-77(115)63(45-66(82)104)98-76(114)62(90-50(4)101)44-53-31-35-55(103)36-32-53)74(112)97-64(46-67(83)105)78(116)99-65(48-100)79(117)96-61(43-51-24-18-17-19-25-51)72(110)89-47-70(108)92-60(41-49(2)3)75(113)94-57(27-23-40-88-81(85)86)73(111)95-59(71(84)109)42-52-29-33-54(102)34-30-52/h17-19,24-25,29-36,49,56-65,100,102-103H,5-16,20-23,26-28,37-48H2,1-4H3,(H2,82,104)(H2,83,105)(H2,84,109)(H,87,106)(H,89,110)(H,90,101)(H,91,107)(H,92,108)(H,93,115)(H,94,113)(H,95,111)(H,96,117)(H,97,112)(H,98,114)(H,99,116)(H,118,119)(H4,85,86,88)/t56-,57-,58-,59-,60-,61-,62-,63-,64-,65-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082065 (CHEMBL3422516) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1cn(nn1)[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(O)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082066 (CHEMBL3422517) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1cn(nn1)[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(O)=O |r| Show InChI InChI=1S/C82H124N20O19/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-28-71(110)92-60(81(120)121)37-38-70(109)88-39-22-21-26-58(93-77(116)64(45-68(83)107)98-76(115)63(91-51(4)104)44-54-31-35-57(106)36-32-54)75(114)97-65(46-69(84)108)78(117)99-66(49-103)79(118)96-62(43-52-24-18-17-19-25-52)73(112)90-47-55-48-102(101-100-55)67(41-50(2)3)80(119)94-59(27-23-40-89-82(86)87)74(113)95-61(72(85)111)42-53-29-33-56(105)34-30-53/h17-19,24-25,29-36,48,50,58-67,103,105-106H,5-16,20-23,26-28,37-47,49H2,1-4H3,(H2,83,107)(H2,84,108)(H2,85,111)(H,88,109)(H,90,112)(H,91,104)(H,92,110)(H,93,116)(H,94,119)(H,95,113)(H,96,118)(H,97,114)(H,98,115)(H,99,117)(H,120,121)(H4,86,87,89)/t58-,59-,60-,61-,62-,63-,64-,65-,66-,67-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	216	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082067 (CHEMBL3422413) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082068 (CHEMBL3422414) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C62H89N17O17/c1-33(2)25-44(57(92)74-42(14-10-24-69-62(66)67)55(90)75-43(53(65)88)26-37-15-19-39(83)20-16-37)72-52(87)31-70-54(89)45(27-36-11-6-5-7-12-36)76-61(96)49(32-80)79-60(95)48(30-51(64)86)77-56(91)41(13-8-9-23-68-34(3)81)73-59(94)47(29-50(63)85)78-58(93)46(71-35(4)82)28-38-17-21-40(84)22-18-38/h5-7,11-12,15-22,33,41-49,80,83-84H,8-10,13-14,23-32H2,1-4H3,(H2,63,85)(H2,64,86)(H2,65,88)(H,68,81)(H,70,89)(H,71,82)(H,72,87)(H,73,94)(H,74,92)(H,75,90)(H,76,96)(H,77,91)(H,78,93)(H,79,95)(H4,66,67,69)/t41-,42-,43-,44-,45-,46-,47-,48-,49-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082069 (CHEMBL3422510) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082070 (CHEMBL3422511) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCNC(C)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.20	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082071 (CHEMBL3422512) Show SMILES CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	182	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082072 (CHEMBL3422513) Show SMILES CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI InChI=1S/C76H117N17O17/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-28-65(100)82-37-22-21-26-54(87-73(108)60(43-63(77)98)92-72(107)59(85-48(4)95)42-51-31-35-53(97)36-32-51)70(105)91-61(44-64(78)99)74(109)93-62(46-94)75(110)90-58(41-49-24-18-17-19-25-49)68(103)84-45-66(101)86-57(39-47(2)3)71(106)88-55(27-23-38-83-76(80)81)69(104)89-56(67(79)102)40-50-29-33-52(96)34-30-50/h17-19,24-25,29-36,47,54-62,94,96-97H,5-16,20-23,26-28,37-46H2,1-4H3,(H2,77,98)(H2,78,99)(H2,79,102)(H,82,100)(H,84,103)(H,85,95)(H,86,101)(H,87,108)(H,88,106)(H,89,104)(H,90,110)(H,91,105)(H,92,107)(H,93,109)(H4,80,81,83)/t54-,55-,56-,57-,58-,59-,60-,61-,62-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>500	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
Neuropeptide FF receptor 1 (Homo sapiens (Human))	BDBM50082073 (CHEMBL3422407) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human NPFF1R expressed in CHO cells assessed as effect on forskolin-induced cAMP accumulation after 15 mins by luminescence based...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
Neuropeptide FF receptor 1 (Homo sapiens (Human))	BDBM50082074 (CHEMBL3422408) Show SMILES CC(C)C[C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)n1cc(CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(C)=O)nn1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human NPFF1R expressed in CHO cells assessed as effect on forskolin-induced cAMP accumulation after 15 mins by luminescence based...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
Neuropeptide FF receptor 1 (Homo sapiens (Human))	BDBM50082065 (CHEMBL3422516) Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCc1cn(nn1)[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(O)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	222	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human NPFF1R expressed in CHO cells assessed as effect on forskolin-induced cAMP accumulation after 15 mins by luminescence based...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082075 (CHEMBL3422406) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082074 (CHEMBL3422408) Show SMILES CC(C)C[C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)n1cc(CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(C)=O)nn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0700	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082076 (CHEMBL3422409) Show SMILES CC(C)C[C@H](NC(=O)Cn1cc(nn1)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082077 (CHEMBL3422410) Show SMILES CC(C)C[C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)n1cc(Cn2cc(nn2)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(C)=O)nn1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082078 (CHEMBL3422411) Show SMILES CC(C)C[C@H](NC(=O)NNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.00600	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082079 (CHEMBL3422412) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCNC(C)=O)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.900	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
KiSS-1 receptor (Homo sapiens (Human))	BDBM50082073 (CHEMBL3422407) Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0700	n/a	n/a	n/a	n/a
UMR7247; Universit£ Fran£ois Rabelais Tours; IFCE) Curated by ChEMBL					Assay Description Agonist activity at human wild-type KISS1R expressed in HEK293 cells assessed as induction of intracellular Ca2+ mobilization after 30 mins by Fluo4 ...				J Med Chem 58: 3459-70 (2015) Article DOI: 10.1021/jm5019675 BindingDB Entry DOI: 10.7270/Q2JD4ZHJ
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334012 (4-(3-(1-isopropyl-4-(3-(trifluoromethyl)phenyl)-1H...) Show SMILES CC(C)n1cc(nc1-c1cccc(CN2CCOCC2)c1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H26F3N3O/c1-17(2)30-16-22(19-6-4-8-21(14-19)24(25,26)27)28-23(30)20-7-3-5-18(13-20)15-29-9-11-31-12-10-29/h3-8,13-14,16-17H,9-12,15H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334013 (4-(3-(1-(cyclopropylmethyl)-4-(3-(trifluoromethyl)...) Show SMILES FC(F)(F)c1cccc(c1)-c1cn(CC2CC2)c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C25H26F3N3O/c26-25(27,28)22-6-2-4-20(14-22)23-17-31(16-18-7-8-18)24(29-23)21-5-1-3-19(13-21)15-30-9-11-32-12-10-30/h1-6,13-14,17-18H,7-12,15-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334014 (4-(3-(1-benzyl-4-(3-(trifluoromethyl)phenyl)-1H-im...) Show SMILES FC(F)(F)c1cccc(c1)-c1cn(Cc2ccccc2)c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C28H26F3N3O/c29-28(30,31)25-11-5-9-23(17-25)26-20-34(19-21-6-2-1-3-7-21)27(32-26)24-10-4-8-22(16-24)18-33-12-14-35-15-13-33/h1-11,16-17,20H,12-15,18-19H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334015 (1-(2-(3-(morpholinomethyl)phenyl)-4-(3-(trifluorom...) Show SMILES CC(=O)n1cc(nc1-c1cccc(CN2CCOCC2)c1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C23H22F3N3O2/c1-16(30)29-15-21(18-5-3-7-20(13-18)23(24,25)26)27-22(29)19-6-2-4-17(12-19)14-28-8-10-31-11-9-28/h2-7,12-13,15H,8-11,14H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334011 (4-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C21H20F3N3O/c22-21(23,24)18-6-2-4-16(12-18)19-13-25-20(26-19)17-5-1-3-15(11-17)14-27-7-9-28-10-8-27/h1-6,11-13H,7-10,14H2,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334016 (4-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(CN2CCSCC2)c1 Show InChI InChI=1S/C21H20F3N3S/c22-21(23,24)18-6-2-4-16(12-18)19-13-25-20(26-19)17-5-1-3-15(11-17)14-27-7-9-28-10-8-27/h1-6,11-13H,7-10,14H2,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334017 (2-methyl-4-(3-(4-(3-(trifluoromethyl)phenyl)-1H-im...) Show SMILES CC1CN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)CCO1 Show InChI InChI=1S/C22H22F3N3O/c1-15-13-28(8-9-29-15)14-16-4-2-6-18(10-16)21-26-12-20(27-21)17-5-3-7-19(11-17)22(23,24)25/h2-7,10-12,15H,8-9,13-14H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334018 (1-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazol-2-...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(CN2CCCCC2)c1 Show InChI InChI=1S/C22H22F3N3/c23-22(24,25)19-9-5-7-17(13-19)20-14-26-21(27-20)18-8-4-6-16(12-18)15-28-10-2-1-3-11-28/h4-9,12-14H,1-3,10-11,15H2,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334019 (4-methyl-1-(3-(4-(3-(trifluoromethyl)phenyl)-1H-im...) Show SMILES CC1CCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C23H24F3N3/c1-16-8-10-29(11-9-16)15-17-4-2-6-19(12-17)22-27-14-21(28-22)18-5-3-7-20(13-18)23(24,25)26/h2-7,12-14,16H,8-11,15H2,1H3,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334020 (4-fluoro-1-(3-(4-(3-(trifluoromethyl)phenyl)-1H-im...) Show SMILES FC1CCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C22H21F4N3/c23-19-7-9-29(10-8-19)14-15-3-1-5-17(11-15)21-27-13-20(28-21)16-4-2-6-18(12-16)22(24,25)26/h1-6,11-13,19H,7-10,14H2,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.29E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334021 (4,4-difluoro-1-(3-(4-(3-(trifluoromethyl)phenyl)-1...) Show SMILES FC(F)(F)c1cccc(c1)-c1c[nH]c(n1)-c1cccc(CN2CCC(F)(F)CC2)c1 Show InChI InChI=1S/C22H20F5N3/c23-21(24)7-9-30(10-8-21)14-15-3-1-5-17(11-15)20-28-13-19(29-20)16-4-2-6-18(12-16)22(25,26)27/h1-6,11-13H,7-10,14H2,(H,28,29)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334022 ((S)-1-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazo...) Show SMILES O[C@H]1CCCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)C1 |r| Show InChI InChI=1S/C22H22F3N3O/c23-22(24,25)18-7-2-5-16(11-18)20-12-26-21(27-20)17-6-1-4-15(10-17)13-28-9-3-8-19(29)14-28/h1-2,4-7,10-12,19,29H,3,8-9,13-14H2,(H,26,27)/t19-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334023 ((1-(3-(4-(3-(trifluoromethyl)phenyl)-1H-imidazol-2...) Show SMILES OCC1CCCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)C1 Show InChI InChI=1S/C23H24F3N3O/c24-23(25,26)20-8-2-6-18(11-20)21-12-27-22(28-21)19-7-1-4-16(10-19)13-29-9-3-5-17(14-29)15-30/h1-2,4,6-8,10-12,17,30H,3,5,9,13-15H2,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334024 (4-(3-(4-(3-bromophenyl)-1H-imidazol-2-yl)benzyl)mo...) Show SMILES Brc1cccc(c1)-c1c[nH]c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C20H20BrN3O/c21-18-6-2-4-16(12-18)19-13-22-20(23-19)17-5-1-3-15(11-17)14-24-7-9-25-10-8-24/h1-6,11-13H,7-10,14H2,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	665	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334025 (4-(3-(4-(3-chlorophenyl)-1H-imidazol-2-yl)benzyl)-...) Show SMILES CC1CN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(Cl)c2)CCO1 Show InChI InChI=1S/C21H22ClN3O/c1-15-13-25(8-9-26-15)14-16-4-2-6-18(10-16)21-23-12-20(24-21)17-5-3-7-19(22)11-17/h2-7,10-12,15H,8-9,13-14H2,1H3,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334026 (1-(3-(4-(3-chlorophenyl)-1H-imidazol-2-yl)benzyl)-...) Show SMILES FC1CCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(Cl)c2)CC1 Show InChI InChI=1S/C21H21ClFN3/c22-18-6-2-4-16(12-18)20-13-24-21(25-20)17-5-1-3-15(11-17)14-26-9-7-19(23)8-10-26/h1-6,11-13,19H,7-10,14H2,(H,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334027 (1-(3-(4-(2,3-dichlorophenyl)-1H-imidazol-2-yl)benz...) Show SMILES CC1CCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(Cl)c2Cl)CC1 Show InChI InChI=1S/C22H23Cl2N3/c1-15-8-10-27(11-9-15)14-16-4-2-5-17(12-16)22-25-13-20(26-22)18-6-3-7-19(23)21(18)24/h2-7,12-13,15H,8-11,14H2,1H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334028 (1-(3-(4-(2,3-dichlorophenyl)-1H-imidazol-2-yl)benz...) Show SMILES FC1CCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2cccc(Cl)c2Cl)CC1 Show InChI InChI=1S/C21H20Cl2FN3/c22-18-6-2-5-17(20(18)23)19-12-25-21(26-19)15-4-1-3-14(11-15)13-27-9-7-16(24)8-10-27/h1-6,11-12,16H,7-10,13H2,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334029 (1-(3-(4-(2,4-dichlorophenyl)-1H-imidazol-2-yl)benz...) Show SMILES FC1CCN(Cc2cccc(c2)-c2nc(c[nH]2)-c2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C21H20Cl2FN3/c22-16-4-5-18(19(23)11-16)20-12-25-21(26-20)15-3-1-2-14(10-15)13-27-8-6-17(24)7-9-27/h1-5,10-12,17H,6-9,13H2,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334030 (4,4-difluoro-1-(3-(4-(2-fluoro-4-methoxyphenyl)-1H...) Show SMILES COc1ccc(-c2c[nH]c(n2)-c2cccc(CN3CCC(F)(F)CC3)c2)c(F)c1 Show InChI InChI=1S/C22H22F3N3O/c1-29-17-5-6-18(19(23)12-17)20-13-26-21(27-20)16-4-2-3-15(11-16)14-28-9-7-22(24,25)8-10-28/h2-6,11-13H,7-10,14H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334031 (4-(3-(4-(2-fluoro-5-methoxyphenyl)-1H-imidazol-2-y...) Show SMILES COc1ccc(F)c(c1)-c1c[nH]c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C21H22FN3O2/c1-26-17-5-6-19(22)18(12-17)20-13-23-21(24-20)16-4-2-3-15(11-16)14-25-7-9-27-10-8-25/h2-6,11-13H,7-10,14H2,1H3,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334032 (4,4-difluoro-1-(3-(4-(2-fluoro-5-methoxyphenyl)-1H...) Show SMILES COc1ccc(F)c(c1)-c1c[nH]c(n1)-c1cccc(CN2CCC(F)(F)CC2)c1 Show InChI InChI=1S/C22H22F3N3O/c1-29-17-5-6-19(23)18(12-17)20-13-26-21(27-20)16-4-2-3-15(11-16)14-28-9-7-22(24,25)8-10-28/h2-6,11-13H,7-10,14H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334033 (4-fluoro-1-(3-(4-(2-fluoro-5-methoxyphenyl)-1H-imi...) Show SMILES COc1ccc(F)c(c1)-c1c[nH]c(n1)-c1cccc(CN2CCC(F)CC2)c1 Show InChI InChI=1S/C22H23F2N3O/c1-28-18-5-6-20(24)19(12-18)21-13-25-22(26-21)16-4-2-3-15(11-16)14-27-9-7-17(23)8-10-27/h2-6,11-13,17H,7-10,14H2,1H3,(H,25,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334034 (4-fluoro-1-(2-(4-(3-(trifluoromethyl)phenyl)-1H-im...) Show SMILES FC1CCN(Cc2ccccc2-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C22H21F4N3/c23-18-8-10-29(11-9-18)14-16-4-1-2-7-19(16)21-27-13-20(28-21)15-5-3-6-17(12-15)22(24,25)26/h1-7,12-13,18H,8-11,14H2,(H,27,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50334035 (2-methyl-4-(2-(4-(3-(trifluoromethyl)phenyl)-1H-im...) Show SMILES CC1CN(Cc2ccccc2-c2nc(c[nH]2)-c2cccc(c2)C(F)(F)F)CCO1 Show InChI InChI=1S/C22H22F3N3O/c1-15-13-28(9-10-29-15)14-17-5-2-3-8-19(17)21-26-12-20(27-21)16-6-4-7-18(11-16)22(23,24)25/h2-8,11-12,15H,9-10,13-14H2,1H3,(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334012 (4-(3-(1-isopropyl-4-(3-(trifluoromethyl)phenyl)-1H...) Show SMILES CC(C)n1cc(nc1-c1cccc(CN2CCOCC2)c1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H26F3N3O/c1-17(2)30-16-22(19-6-4-8-21(14-19)24(25,26)27)28-23(30)20-7-3-5-18(13-20)15-29-9-11-31-12-10-29/h3-8,13-14,16-17H,9-12,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	218	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334013 (4-(3-(1-(cyclopropylmethyl)-4-(3-(trifluoromethyl)...) Show SMILES FC(F)(F)c1cccc(c1)-c1cn(CC2CC2)c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C25H26F3N3O/c26-25(27,28)22-6-2-4-20(14-22)23-17-31(16-18-7-8-18)24(29-23)21-5-1-3-19(13-21)15-30-9-11-32-12-10-30/h1-6,13-14,17-18H,7-12,15-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	412	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50334014 (4-(3-(1-benzyl-4-(3-(trifluoromethyl)phenyl)-1H-im...) Show SMILES FC(F)(F)c1cccc(c1)-c1cn(Cc2ccccc2)c(n1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C28H26F3N3O/c29-28(30,31)25-11-5-9-23(17-25)26-20-34(19-21-6-2-1-3-7-21)27(32-26)24-10-4-8-22(16-24)18-33-12-14-35-15-13-33/h1-11,16-17,20H,12-15,18-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratory Curated by ChEMBL					Assay Description Agonist activity at human cloned CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation				Bioorg Med Chem Lett 21: 182-5 (2010) Article DOI: 10.1016/j.bmcl.2010.11.044 BindingDB Entry DOI: 10.7270/Q20P108G
					More data for this Ligand-Target Pair

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