Compile Data Set for Download or QSAR

Found 73 hits with Last Name = 'carnell' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50278288 (2-(2-(4-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4...) Show SMILES OCCOCCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C20H23N5O2/c26-6-8-27-7-5-21-19-11-17-18(12-22-19)23-13-24-20(17)25-16-9-14-3-1-2-4-15(14)10-16/h1-4,11-13,16,26H,5-10H2,(H,21,22)(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278286 (CHEMBL511266 | N4-(2,3-dihydro-1H-inden-2-yl)-N6-(...) Show SMILES COCCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C19H21N5O/c1-25-7-6-20-18-10-16-17(11-21-18)22-12-23-19(16)24-15-8-13-4-2-3-5-14(13)9-15/h2-5,10-12,15H,6-9H2,1H3,(H,20,21)(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278407 (CHEMBL470396 | N-cycloheptyl-6-(2-morpholinoethoxy...) Show SMILES C(CN1CCOCC1)Oc1cc2c(NC3CCCCCC3)ncnc2cn1 Show InChI InChI=1S/C20H29N5O2/c1-2-4-6-16(5-3-1)24-20-17-13-19(21-14-18(17)22-15-23-20)27-12-9-25-7-10-26-11-8-25/h13-16H,1-12H2,(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278361 (CHEMBL471435 | N4-cyclohexyl-N6-(2-morpholinoethyl...) Show SMILES C(CN1CCOCC1)Nc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C19H28N6O/c1-2-4-15(5-3-1)24-19-16-12-18(21-13-17(16)22-14-23-19)20-6-7-25-8-10-26-11-9-25/h12-15H,1-11H2,(H,20,21)(H,22,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278289 (CHEMBL469383 | N4-cyclohexyl-N6-(2-methoxyethyl)py...) Show SMILES COCCNc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C16H23N5O/c1-22-8-7-17-15-9-13-14(10-18-15)19-11-20-16(13)21-12-5-3-2-4-6-12/h9-12H,2-8H2,1H3,(H,17,18)(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278112 (CHEMBL472490 | N4-(2,3-dihydro-1H-inden-2-yl)-N6-m...) Show SMILES CNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C17H17N5/c1-18-16-8-14-15(9-19-16)20-10-21-17(14)22-13-6-11-4-2-3-5-12(11)7-13/h2-5,8-10,13H,6-7H2,1H3,(H,18,19)(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278358 (1-(2-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-...) Show SMILES O=C1CCCN1CCOc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C19H25N5O2/c25-18-7-4-8-24(18)9-10-26-17-11-15-16(12-20-17)21-13-22-19(15)23-14-5-2-1-3-6-14/h11-14H,1-10H2,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278232 (2-(4-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4-d]...) Show SMILES OCCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C18H19N5O/c24-6-5-19-17-9-15-16(10-20-17)21-11-22-18(15)23-14-7-12-3-1-2-4-13(12)8-14/h1-4,9-11,14,24H,5-8H2,(H,19,20)(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278114 (CHEMBL513012 | N-cyclohexylquinazolin-4-amine) Show SMILES C1CCC(CC1)Nc1ncnc2ccccc12 Show InChI InChI=1S/C14H17N3/c1-2-6-11(7-3-1)17-14-12-8-4-5-9-13(12)15-10-16-14/h4-5,8-11H,1-3,6-7H2,(H,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278231 (CHEMBL513018 | N4,N6-bis(2,3-dihydro-1H-inden-2-yl...) Show SMILES C1C(Cc2ccccc12)Nc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C25H23N5/c1-2-6-17-10-20(9-16(17)5-1)29-24-13-22-23(14-26-24)27-15-28-25(22)30-21-11-18-7-3-4-8-19(18)12-21/h1-8,13-15,20-21H,9-12H2,(H,26,29)(H,27,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278357 (3-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-ylo...) Show SMILES OCCCOc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C16H22N4O2/c21-7-4-8-22-15-9-13-14(10-17-15)18-11-19-16(13)20-12-5-2-1-3-6-12/h9-12,21H,1-8H2,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278153 (CHEMBL471242 | N-(2,3-dihydro-1H-inden-2-yl)quinaz...) Show SMILES C1C(Cc2ccccc12)Nc1ncnc2ccccc12 Show InChI InChI=1S/C17H15N3/c1-2-6-13-10-14(9-12(13)5-1)20-17-15-7-3-4-8-16(15)18-11-19-17/h1-8,11,14H,9-10H2,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278362 (CHEMBL512523 | N-cyclohexyl-6-(2-morpholinoethoxy)...) Show SMILES C(CN1CCOCC1)Oc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C19H27N5O2/c1-2-4-15(5-3-1)23-19-16-12-18(20-13-17(16)21-14-22-19)26-11-8-24-6-9-25-10-7-24/h12-15H,1-11H2,(H,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278111 (CHEMBL472489 | N4-(2,3-dihydro-1H-inden-2-yl)-N4,N...) Show SMILES CNc1cc2c(ncnc2cn1)N(C)C1Cc2ccccc2C1 Show InChI InChI=1S/C18H19N5/c1-19-17-9-15-16(10-20-17)21-11-22-18(15)23(2)14-7-12-5-3-4-6-13(12)8-14/h3-6,9-11,14H,7-8H2,1-2H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278291 (CHEMBL471666 | N-cyclohexyl-6-(2-methoxyethoxy)pyr...) Show SMILES COCCOc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C16H22N4O2/c1-21-7-8-22-15-9-13-14(10-17-15)18-11-19-16(13)20-12-5-3-2-4-6-12/h9-12H,2-8H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278287 (CHEMBL469381 | N4-(2,3-dihydro-1H-inden-2-yl)-N6-(...) Show SMILES CN(C)CCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C20H24N6/c1-26(2)8-7-21-19-11-17-18(12-22-19)23-13-24-20(17)25-16-9-14-5-3-4-6-15(14)10-16/h3-6,11-13,16H,7-10H2,1-2H3,(H,21,22)(H,23,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278113 (CHEMBL513761 | N-(2,3-dihydro-1H-inden-2-yl)-6-met...) Show SMILES COc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C17H16N4O/c1-22-16-8-14-15(9-18-16)19-10-20-17(14)21-13-6-11-4-2-3-5-12(11)7-13/h2-5,8-10,13H,6-7H2,1H3,(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278229 (2-(6-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4-d]...) Show SMILES OCCNc1ncnc2cnc(NC3Cc4ccccc4C3)cc12 Show InChI InChI=1S/C18H19N5O/c24-6-5-19-18-15-9-17(20-10-16(15)21-11-22-18)23-14-7-12-3-1-2-4-13(12)8-14/h1-4,9-11,14,24H,5-8H2,(H,20,23)(H,19,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278228 (CHEMBL447113 | N6-(2,3-dihydro-1H-inden-2-yl)-N4-m...) Show SMILES CNc1ncnc2cnc(NC3Cc4ccccc4C3)cc12 Show InChI InChI=1S/C17H17N5/c1-18-17-14-8-16(19-9-15(14)20-10-21-17)22-13-6-11-4-2-3-5-12(11)7-13/h2-5,8-10,13H,6-7H2,1H3,(H,19,22)(H,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278290 (2-(4-(cyclohexylamino)pyrido[3,4-d]pyrimidin-6-ylo...) Show SMILES OCCOc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C15H20N4O2/c20-6-7-21-14-8-12-13(9-16-14)17-10-18-15(12)19-11-4-2-1-3-5-11/h8-11,20H,1-7H2,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278853 (CHEMBL496897 | N4-(2,3-dihydro-1H-inden-2-yl)-N6,N...) Show SMILES CN(C)c1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C18H19N5/c1-23(2)17-9-15-16(10-19-17)20-11-21-18(15)22-14-7-12-5-3-4-6-13(12)8-14/h3-6,9-11,14H,7-8H2,1-2H3,(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	185	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278850 (CHEMBL497918 | N4-cyclohexyl-N6,N6-dimethylpyrido[...) Show SMILES CN(C)c1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C15H21N5/c1-20(2)14-8-12-13(9-16-14)17-10-18-15(12)19-11-6-4-3-5-7-11/h8-11H,3-7H2,1-2H3,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	199	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278360 (CHEMBL471434 | N6-(3-aminopropyl)-N4-cyclohexylpyr...) Show SMILES NCCCNc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C16H24N6/c17-7-4-8-18-15-9-13-14(10-19-15)20-11-21-16(13)22-12-5-2-1-3-6-12/h9-12H,1-8,17H2,(H,18,19)(H,20,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278110 (CHEMBL511838 | N4-(2,3-dihydro-1H-inden-2-yl)-N4,N...) Show SMILES CN(C)c1cc2c(ncnc2cn1)N(C)C1Cc2ccccc2C1 Show InChI InChI=1S/C19H21N5/c1-23(2)18-10-16-17(11-20-18)21-12-22-19(16)24(3)15-8-13-6-4-5-7-14(13)9-15/h4-7,10-12,15H,8-9H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278116 (4-(cyclohexyloxy)quinazoline | CHEMBL471866) Show SMILES C1CCC(CC1)Oc1ncnc2ccccc12 Show InChI InChI=1S/C14H16N2O/c1-2-6-11(7-3-1)17-14-12-8-4-5-9-13(12)15-10-16-14/h4-5,8-11H,1-3,6-7H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	694	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278852 (CHEMBL525546 | N6,N6-dimethyl-N4-(pentan-2-yl)pyri...) Show SMILES CCCC(C)Nc1ncnc2cnc(cc12)N(C)C Show InChI InChI=1S/C14H21N5/c1-5-6-10(2)18-14-11-7-13(19(3)4)15-8-12(11)16-9-17-14/h7-10H,5-6H2,1-4H3,(H,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	858	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278851 ((S)-N6,N6-dimethyl-N4-(1-phenylethyl)pyrido[3,4-d]...) Show SMILES C[C@H](Nc1ncnc2cnc(cc12)N(C)C)c1ccccc1 |r| Show InChI InChI=1S/C17H19N5/c1-12(13-7-5-4-6-8-13)21-17-14-9-16(22(2)3)18-10-15(14)19-11-20-17/h4-12H,1-3H3,(H,19,20,21)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278227 (CHEMBL470205 | N-(2,3-dihydro-1H-inden-2-yl)isoqui...) Show SMILES C1C(Cc2ccccc12)Nc1nccc2ccccc12 Show InChI InChI=1S/C18H16N2/c1-2-7-15-12-16(11-14(15)6-1)20-18-17-8-4-3-5-13(17)9-10-19-18/h1-10,16H,11-12H2,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278359 (CHEMBL509066 | N6-(2-aminoethyl)-N4-cyclohexylpyri...) Show SMILES NCCNc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C15H22N6/c16-6-7-17-14-8-12-13(9-18-14)19-10-20-15(12)21-11-4-2-1-3-5-11/h8-11H,1-7,16H2,(H,17,18)(H,19,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278230 (2,2'-(pyrido[3,4-d]pyrimidine-4,6-diylbis(azanediy...) Show SMILES OCCNc1cc2c(NCCO)ncnc2cn1 Show InChI InChI=1S/C11H15N5O2/c17-3-1-12-10-5-8-9(6-14-10)15-7-16-11(8)13-2-4-18/h5-7,17-18H,1-4H2,(H,12,14)(H,13,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50278115 (CHEMBL449616 | N-cyclohexylquinolin-4-amine) Show SMILES C1CCC(CC1)Nc1ccnc2ccccc12 Show InChI InChI=1S/C15H18N2/c1-2-6-12(7-3-1)17-15-10-11-16-14-9-5-4-8-13(14)15/h4-5,8-12H,1-3,6-7H2,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50278288 (2-(2-(4-(2,3-dihydro-1H-inden-2-ylamino)pyrido[3,4...) Show SMILES OCCOCCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 Show InChI InChI=1S/C20H23N5O2/c26-6-8-27-7-5-21-19-11-17-18(12-22-19)23-13-24-20(17)25-16-9-14-3-1-2-4-15(14)10-16/h1-4,11-13,16,26H,5-10H2,(H,21,22)(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at mGluR1				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305900 ((+)-2-((1S,5S,6R)-6-(aminomethyl)bicyclo[3.2.0]hep...) Show SMILES NC[C@@]1(CC(O)=O)C[C@@H]2CCC[C@H]12 |r| Show InChI InChI=1S/C10H17NO2/c11-6-10(5-9(12)13)4-7-2-1-3-8(7)10/h7-8H,1-6,11H2,(H,12,13)/t7-,8-,10-/m0/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305887 (3,4-trans-2-(1-(aminomethyl)-3,4-dimethylcyclopent...) Show SMILES C[C@H]1CC(CN)(CC(O)=O)C[C@@H]1C |r| Show InChI InChI=1S/C10H19NO2/c1-7-3-10(6-11,4-8(7)2)5-9(12)13/h7-8H,3-6,11H2,1-2H3,(H,12,13)/t7-,8-/m0/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305894 ((+/-)-2-((6S)-6-(aminomethyl)bicyclo[3.2.0]heptan-...) Show SMILES NC[C@]1(CC(O)=O)CC2CCCC12 |r| Show InChI InChI=1S/C10H17NO2/c11-6-10(5-9(12)13)4-7-2-1-3-8(7)10/h7-8H,1-6,11H2,(H,12,13)/t7?,8?,10-/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304703 (2-((3R)-1-(aminomethyl)-3-propylcyclopentyl)acetic...) Show SMILES CCC[C@@H]1CCC(CN)(CC(O)=O)C1 |r| Show InChI InChI=1S/C11H21NO2/c1-2-3-9-4-5-11(6-9,8-12)7-10(13)14/h9H,2-8,12H2,1H3,(H,13,14)/t9-,11?/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304707 (2-((1R,3R)-1-(aminomethyl)-3-methylcyclopentyl)ace...) Show SMILES C[C@@H]1CC[C@](CN)(CC(O)=O)C1 |r| Show InChI InChI=1S/C9H17NO2/c1-7-2-3-9(4-7,6-10)5-8(11)12/h7H,2-6,10H2,1H3,(H,11,12)/t7-,9-/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305885 (CHEMBL595172 | cis-2-((1R,5S)-3-(aminomethyl)bicyc...) Show SMILES NC[C@@]1(CC(O)=O)C[C@@H]2CC[C@@H]2C1 |r| Show InChI InChI=1S/C10H17NO2/c11-6-10(5-9(12)13)3-7-1-2-8(7)4-10/h7-8H,1-6,11H2,(H,12,13)/t7-,8+,10-	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305899 ((-)-2-((1R,5R,6S)-6-(aminomethyl)bicyclo[3.2.0]hep...) Show SMILES NC[C@]1(CC(O)=O)C[C@H]2CCC[C@@H]12 |r| Show InChI InChI=1S/C10H17NO2/c11-6-10(5-9(12)13)4-7-2-1-3-8(7)10/h7-8H,1-6,11H2,(H,12,13)/t7-,8-,10-/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304702 (2-((3R)-1-(aminomethyl)-3-ethylcyclopentyl)acetic ...) Show SMILES CC[C@@H]1CCC(CN)(CC(O)=O)C1 |r| Show InChI InChI=1S/C10H19NO2/c1-2-8-3-4-10(5-8,7-11)6-9(12)13/h8H,2-7,11H2,1H3,(H,12,13)/t8-,10?/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304693 (2-(1-(aminomethyl)-3-ethylcyclopentyl)acetic acid ...) Show SMILES CCC1CCC(CN)(CC(O)=O)C1 Show InChI InChI=1S/C10H19NO2/c1-2-8-3-4-10(5-8,7-11)6-9(12)13/h8H,2-7,11H2,1H3,(H,12,13)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304694 (2-(1-(aminomethyl)-3-propylcyclopentyl)acetic acid...) Show SMILES CCCC1CCC(CN)(CC(O)=O)C1 Show InChI InChI=1S/C11H21NO2/c1-2-3-9-4-5-11(6-9,8-12)7-10(13)14/h9H,2-8,12H2,1H3,(H,13,14)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304708 (2-((1S,3R)-1-(aminomethyl)-3-methylcyclopentyl)ace...) Show SMILES C[C@@H]1CC[C@@](CN)(CC(O)=O)C1 |r| Show InChI InChI=1S/C9H17NO2/c1-7-2-3-9(4-7,6-10)5-8(11)12/h7H,2-6,10H2,1H3,(H,11,12)/t7-,9+/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50164279 ((S)-3-(aminomethyl)-5-methylhexanoic acid | (S)-3-...) Show SMILES CC(C)C[C@H](CN)CC(O)=O |r| Show InChI InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304692 (2-(1-(aminomethyl)-3-methylcyclopentyl)acetic acid...) Show SMILES CC1CCC(CN)(CC(O)=O)C1 Show InChI InChI=1S/C9H17NO2/c1-7-2-3-9(4-7,6-10)5-8(11)12/h7H,2-6,10H2,1H3,(H,11,12)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50304701 (2-((3R)-1-(aminomethyl)-3-methylcyclopentyl)acetic...) Show SMILES C[C@@H]1CCC(CN)(CC(O)=O)C1 |r| Show InChI InChI=1S/C9H17NO2/c1-7-2-3-9(4-7,6-10)5-8(11)12/h7H,2-6,10H2,1H3,(H,11,12)/t7-,9?/m1/s1	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305886 (2-((3R,4S)-1-(aminomethyl)-3,4-dimethylcyclopentyl...) Show SMILES C[C@H]1C[C@](CN)(CC(O)=O)C[C@H]1C |r| Show InChI InChI=1S/C10H19NO2/c1-7-3-10(6-11,4-8(7)2)5-9(12)13/h7-8H,3-6,11H2,1-2H3,(H,12,13)/t7-,8+,10+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50080153 ((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...) Show SMILES NCC1(CC(O)=O)CCCCC1 Show InChI InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 362-5 (2010) Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50278849 (CHEMBL497917 | N4-(3-chloro-4-fluorophenyl)pyrido[...) Show SMILES Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cn1 Show InChI InChI=1S/C13H9ClFN5/c14-9-3-7(1-2-10(9)15)20-13-8-4-12(16)17-5-11(8)18-6-19-13/h1-6H,(H2,16,17)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at mGluR1				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
					More data for this Ligand-Target Pair
Voltage-dependent calcium channel alpha-2 delta subunit (Sus scrofa)	BDBM50305884 (CHEMBL609569 | cis-2-((1R,5S)-3-(aminomethyl)bicyc...) Show SMILES NC[C@]1(CC(O)=O)C[C@@H]2CC[C@@H]2C1 |r| Show InChI InChI=1S/C10H17NO2/c11-6-10(5-9(12)13)3-7-1-2-8(7)4-10/h7-8H,1-6,11H2,(H,12,13)/t7-,8+,10+	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	332	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins				Bioorg Med Chem Lett 20: 461-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.118 BindingDB Entry DOI: 10.7270/Q25H7GCQ
					More data for this Ligand-Target Pair

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