Compile Data Set for Download or QSAR

Found 114 hits with Last Name = 'chambers' and Initial = 'jj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098525 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098526 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098532 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/p+1/t7-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098530 (1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098525 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098536 (1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098530 (1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098526 (2-(8-Bromo-benzo[1,2-b;4,5-b']difuran-4-yl)-1-meth...) Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(Br)c2ccoc12 Show InChI InChI=1S/C13H12BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h2-5,7H,6,15H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098536 (1-Methyl-2-(8-trifluoromethyl-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@H]([NH3+])Cc1c2ccoc2c(c2ccoc12)C(F)(F)F Show InChI InChI=1S/C14H12F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h2-5,7H,6,18H2,1H3/p+1/t7-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098527 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2c(c2CCOc12)C(F)(F)F Show InChI InChI=1S/C14H16F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h7H,2-6,18H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098533 (2-Benzo[1,2-b;4,5-b']difuran-4-yl-1-methyl-ethyl-a...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2cc2ccoc12 Show InChI InChI=1S/C13H13NO2/c1-8(14)6-11-10-3-5-15-12(10)7-9-2-4-16-13(9)11/h2-5,7-8H,6,14H2,1H3/p+1/t8-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50115831 (1-Methyl-2-(4-methyl-benzo[1,2-b;5,4-b']difuran-8-...) Show SMILES CC(N)Cc1c2occc2c(C)c2ccoc12 Show InChI InChI=1S/C14H15NO2/c1-8(15)7-12-13-10(3-5-16-13)9(2)11-4-6-17-14(11)12/h3-6,8H,7,15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2C receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50131665 (C-(8-Bromo-6-methoxy-4,5-dihydro-3H-naphtho[1,8-bc...) Show SMILES COc1cc(Br)c2occ3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H14BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,6-7H,2-3,5,15H2,1H3/t7-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Tested in vitro for its ability to bind to 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098534 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/p+1/t7-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098532 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/p+1/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098533 (2-Benzo[1,2-b;4,5-b']difuran-4-yl-1-methyl-ethyl-a...) Show SMILES C[C@@H]([NH3+])Cc1c2ccoc2cc2ccoc12 Show InChI InChI=1S/C13H13NO2/c1-8(14)6-11-10-3-5-15-12(10)7-9-2-4-16-13(9)11/h2-5,7-8H,6,14H2,1H3/p+1/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098535 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) Show SMILES C[C@H]([NH3+])Cc1c2CCOc2c(c2CCOc12)C(F)(F)F Show InChI InChI=1S/C14H16F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h7H,2-6,18H2,1H3/p+1/t7-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50115831 (1-Methyl-2-(4-methyl-benzo[1,2-b;5,4-b']difuran-8-...) Show SMILES CC(N)Cc1c2occc2c(C)c2ccoc12 Show InChI InChI=1S/C14H15NO2/c1-8(15)7-12-13-10(3-5-16-13)9(2)11-4-6-17-14(11)12/h3-6,8H,7,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2A receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098527 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2c(c2CCOc12)C(F)(F)F Show InChI InChI=1S/C14H16F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h7H,2-6,18H2,1H3/p+1/t7-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098535 (1-Methyl-2-(8-trifluoromethyl-2,3,6,7-tetrahydro-b...) Show SMILES C[C@H]([NH3+])Cc1c2CCOc2c(c2CCOc12)C(F)(F)F Show InChI InChI=1S/C14H16F3NO2/c1-7(18)6-10-8-2-4-20-13(8)11(14(15,16)17)9-3-5-19-12(9)10/h7H,2-6,18H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50038370 (2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...) Show SMILES COc1cc(c(OC)cc1CC(C)N)C(F)(F)F Show InChI InChI=1S/C12H16F3NO2/c1-7(16)4-8-5-11(18-3)9(12(13,14)15)6-10(8)17-2/h5-7H,4,16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50131665 (C-(8-Bromo-6-methoxy-4,5-dihydro-3H-naphtho[1,8-bc...) Show SMILES COc1cc(Br)c2occ3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H14BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,6-7H,2-3,5,15H2,1H3/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50098534 (2-(8-Bromo-2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']d...) Show SMILES C[C@H]([NH3+])Cc1c2CCOc2c(Br)c2CCOc12 Show InChI InChI=1S/C13H16BrNO2/c1-7(15)6-10-8-2-4-17-13(8)11(14)9-3-5-16-12(9)10/h7H,2-6,15H2,1H3/p+1/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50005257 ((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...) Show SMILES COc1cc(CC(C)N)c(OC)cc1Br Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50131668 (C-(8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-naphth...) Show SMILES COc1cc(Br)c2OC[C@H]3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H16BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,7-8H,2-3,5-6,15H2,1H3/t7-,8+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2A receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50038370 (2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...) Show SMILES COc1cc(c(OC)cc1CC(C)N)C(F)(F)F Show InChI InChI=1S/C12H16F3NO2/c1-7(16)4-8-5-11(18-3)9(12(13,14)15)6-10(8)17-2/h5-7H,4,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50064706 ((2aS,4R)-8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-...) Show SMILES COc1cc(Br)c2OC[C@H]3C[C@@H](N)Cc1c23 Show InChI InChI=1S/C12H14BrNO2/c1-15-10-4-9(13)12-11-6(5-16-12)2-7(14)3-8(10)11/h4,6-7H,2-3,5,14H2,1H3/t6-,7-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50131669 (C-(8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-naphth...) Show SMILES COc1cc(Br)c2OC[C@@H]3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H16BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,7-8H,2-3,5-6,15H2,1H3/t7-,8-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2C receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098531 (2-Benzo[1,2-b;4,5-b']difuran-4-yl-1-methyl-ethyl-a...) Show SMILES C[C@H]([NH3+])Cc1c2ccoc2cc2ccoc12 Show InChI InChI=1S/C13H13NO2/c1-8(14)6-11-10-3-5-15-12(10)7-9-2-4-16-13(9)11/h2-5,7-8H,6,14H2,1H3/p+1/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50115830 (1-Methyl-2-(4-methyl-2,3,5,6-tetrahydro-benzo[1,2-...) Show SMILES CC(N)Cc1c2OCCc2c(C)c2CCOc12 Show InChI InChI=1S/C14H19NO2/c1-8(15)7-12-13-10(3-5-16-13)9(2)11-4-6-17-14(11)12/h8H,3-7,15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2A receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50034839 (8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tri...) Show SMILES CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI InChI=1S/C15H14ClN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha1beta2gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50115830 (1-Methyl-2-(4-methyl-2,3,5,6-tetrahydro-benzo[1,2-...) Show SMILES CC(N)Cc1c2OCCc2c(C)c2CCOc12 Show InChI InChI=1S/C14H19NO2/c1-8(15)7-12-13-10(3-5-16-13)9(2)11-4-6-17-14(11)12/h8H,3-7,15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace (+/-)[125I]-DOI from 5-hydroxytryptamine 2C receptor in cloned rat cell culture				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50098537 (1-Methyl-2-(2,3,6,7-tetrahydro-benzo[1,2-b;4,5-b']...) Show SMILES C[C@@H]([NH3+])Cc1c2CCOc2cc2CCOc12 Show InChI InChI=1S/C13H17NO2/c1-8(14)6-11-10-3-5-15-12(10)7-9-2-4-16-13(9)11/h7-8H,2-6,14H2,1H3/p+1/t8-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligand				J Med Chem 44: 1003-10 (2001) BindingDB Entry DOI: 10.7270/Q27P8XND
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50131668 (C-(8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-naphth...) Show SMILES COc1cc(Br)c2OC[C@H]3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H16BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,7-8H,2-3,5-6,15H2,1H3/t7-,8+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50034839 (8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tri...) Show SMILES CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI InChI=1S/C15H14ClN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha3beta2gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50131669 (C-(8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-naphth...) Show SMILES COc1cc(Br)c2OC[C@@H]3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H16BrNO2/c1-16-10-4-9(14)13-12-8(6-17-13)3-2-7(5-15)11(10)12/h4,7-8H,2-3,5-6,15H2,1H3/t7-,8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Tested in vitro for its ability to bind to 5-hydroxytryptamine 2A receptor using [125 I]-DOI as radioligand				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50131670 (C-(6-Methoxy-4,5-dihydro-3H-naphtho[1,8-bc]furan-5...) Show SMILES COc1ccc2occ3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H15NO2/c1-15-10-4-5-11-13-9(7-16-11)3-2-8(6-14)12(10)13/h4-5,7-8H,2-3,6,14H2,1H3/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50064706 ((2aS,4R)-8-Bromo-6-methoxy-2a,3,4,5-tetrahydro-2H-...) Show SMILES COc1cc(Br)c2OC[C@H]3C[C@@H](N)Cc1c23 Show InChI InChI=1S/C12H14BrNO2/c1-15-10-4-9(13)12-11-6(5-16-12)2-7(14)3-8(10)11/h4,6-7H,2-3,5,14H2,1H3/t6-,7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50034839 (8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tri...) Show SMILES CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(Cl)ccc-21 Show InChI InChI=1S/C15H14ClN3O3/c1-3-22-15(21)13-12-7-18(2)14(20)10-6-9(16)4-5-11(10)19(12)8-17-13/h4-6,8H,3,7H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Curated by ChEMBL					Assay Description Binding affinity to human recombinant GABA alpha2beta2gamma2 receptor				Bioorg Med Chem 18: 7731-8 (2010) Article DOI: 10.1016/j.bmc.2010.05.056 BindingDB Entry DOI: 10.7270/Q21R6QRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50005265 ((+/-)2-(2,5-Dimethoxy-4-methyl-phenyl)-1-methyl-et...) Show SMILES COc1cc(CC(C)N)c(OC)cc1C Show InChI InChI=1S/C12H19NO2/c1-8-5-12(15-4)10(6-9(2)13)7-11(8)14-3/h5,7,9H,6,13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [125I]-(R)-DOI from 5-hydroxytryptamine 2A receptor in cloned rat prefrontal cortex homogenate				Bioorg Med Chem Lett 12: 1997-9 (2002) BindingDB Entry DOI: 10.7270/Q2BR8RH5
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50081701 (3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...) Show SMILES CN(C)CCc1c[nH]c2cccc(O)c12 Show InChI InChI=1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2A receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50131667 (C-(6-Methoxy-2a,3,4,5-tetrahydro-2H-naphtho[1,8-bc...) Show SMILES COc1ccc2OC[C@@H]3CC[C@@H](CN)c1c23 Show InChI InChI=1S/C13H17NO2/c1-15-10-4-5-11-13-9(7-16-11)3-2-8(6-14)12(10)13/h4-5,8-9H,2-3,6-7,14H2,1H3/t8-,9-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOI				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
					More data for this Ligand-Target Pair

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