Compile Data Set for Download or QSAR

Found 474 hits with Last Name = 'clizbe' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM12751 (1-(3-carbamimidoylphenyl)-3-methyl-N-[4-(2-sulfamo...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1cccc(c1)C(N)=N Show InChI InChI=1S/C24H22N6O3S/c1-15-13-21(30(29-15)19-6-4-5-17(14-19)23(25)26)24(31)28-18-11-9-16(10-12-18)20-7-2-3-8-22(20)34(27,32)33/h2-14H,1H3,(H3,25,26)(H,28,31)(H2,27,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound against Coagulation factor Xa (serine protease) was determined				Bioorg Med Chem Lett 12: 1511-5 (2002) BindingDB Entry DOI: 10.7270/Q2P84B6X
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50193861 (5-chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N,N-dimet...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O2/c1-29(2)20(25)13-3-5-14(6-4-13)21(30)27-18-9-7-15(23)11-17(18)22(31)28-19-10-8-16(24)12-26-19/h3-12,25H,1-2H3,(H,27,30)(H,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50249120 (CHEMBL472967 | N-(4-chloro-2-(5-chloropyridin-2-yl...) Show SMILES CN(C)C(=N)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(F)c1 Show InChI InChI=1S/C22H18Cl2FN5O2/c1-30(2)20(26)12-3-6-15(17(25)9-12)21(31)28-18-7-4-13(23)10-16(18)22(32)29-19-8-5-14(24)11-27-19/h3-11,26H,1-2H3,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM19023 (1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...) Show SMILES COc1ccc(cc1)-n1nc(C(N)=O)c2CCN(C(=O)c12)c1ccc(cc1)N1CCCCC1=O Show InChI InChI=1S/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor X (Homo sapiens (Human))	BDBM50249423 (CHEMBL515919 | N-(2-(5-chloropyridin-2-ylcarbamoyl...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2F)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H21ClFN5O3/c1-30(2)21(26)13-4-7-16(18(25)10-13)22(31)28-19-8-6-15(33-3)11-17(19)23(32)29-20-9-5-14(24)12-27-20/h4-12,26H,1-3H3,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50249298 (BEVYXXA | CHEMBL512351 | N-(5-chloropyridin-2-yl)-...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H22ClN5O3/c1-29(2)21(25)14-4-6-15(7-5-14)22(30)27-19-10-9-17(32-3)12-18(19)23(31)28-20-11-8-16(24)13-26-20/h4-13,25H,1-3H3,(H,27,30)(H,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50113598 ((Z)-3-(3-Carbamimidoyl-4-fluoro-phenyl)-2-fluoro-b...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1Cl)-c1ccccc1S(N)(=O)=O)c1ccc(F)c(c1)C(N)=N Show InChI InChI=1S/C23H19ClF2N4O3S/c1-12(13-6-8-18(25)16(10-13)22(27)28)21(26)23(31)30-19-9-7-14(11-17(19)24)15-4-2-3-5-20(15)34(29,32)33/h2-11H,1H3,(H3,27,28)(H,30,31)(H2,29,32,33)/b21-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity of the compound against factor Xa,activity expressed as Ki nM				Bioorg Med Chem Lett 12: 1511-5 (2002) BindingDB Entry DOI: 10.7270/Q2P84B6X
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140394 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)N2CCOCC2=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C25H21ClN4O3/c1-16-12-23(30(28-16)22-7-3-17-13-19(26)4-2-18(17)14-22)25(32)27-20-5-8-21(9-6-20)29-10-11-33-15-24(29)31/h2-9,12-14H,10-11,15H2,1H3,(H,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM7840 (RIVAROXABAN | US8822458, 44 | US8822458, 97) Show SMILES Clc1ccc(s1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O |r| Show InChI InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Coagulation factor X (Homo sapiens (Human))	BDBM50140371 (2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)N2CCOCC2=O)n(n1)-c1cc2ccccc2cc1F Show InChI InChI=1S/C25H20F2N4O3/c1-15-10-23(31(29-15)22-12-17-5-3-2-4-16(17)11-20(22)27)25(33)28-21-7-6-18(13-19(21)26)30-8-9-34-14-24(30)32/h2-7,10-13H,8-9,14H2,1H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140388 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)N2CCOCC2=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C25H20ClFN4O3/c1-15-10-23(31(29-15)20-5-3-16-11-18(26)4-2-17(16)12-20)25(33)28-22-7-6-19(13-21(22)27)30-8-9-34-14-24(30)32/h2-7,10-13H,8-9,14H2,1H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50123431 (7-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-2...) Show SMILES CC(=N)N1CCC(CC1)Oc1ccc2N(Cc3ccc4ccc(cc4c3)C(N)=N)C(=O)COc2c1 Show InChI InChI=1S/C27H29N5O3/c1-17(28)31-10-8-22(9-11-31)35-23-6-7-24-25(14-23)34-16-26(33)32(24)15-18-2-3-19-4-5-20(27(29)30)13-21(19)12-18/h2-7,12-14,22,28H,8-11,15-16H2,1H3,(H3,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound towards factor Xa				Bioorg Med Chem Lett 13: 561-6 (2003) BindingDB Entry DOI: 10.7270/Q2DB816X
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140370 (2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)N2CCOCC2=O)n(n1)-c1cc2ccccc2cc1S(C)(=O)=O Show InChI InChI=1S/C26H23FN4O5S/c1-16-11-23(26(33)28-21-8-7-19(14-20(21)27)30-9-10-36-15-25(30)32)31(29-16)22-12-17-5-3-4-6-18(17)13-24(22)37(2,34)35/h3-8,11-14H,9-10,15H2,1-2H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115933 ((E)-3-(1-Amino-isoquinolin-7-yl)-2-fluoro-but-2-en...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1Cl)-c1ccccc1S(N)(=O)=O)c1ccc2ccnc(N)c2c1 Show InChI InChI=1S/C25H20ClFN4O3S/c1-14(16-7-6-15-10-11-30-24(28)19(15)12-16)23(27)25(32)31-21-9-8-17(13-20(21)26)18-4-2-3-5-22(18)35(29,33)34/h2-13H,1H3,(H2,28,30)(H,31,32)(H2,29,33,34)/b23-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Concentration required for inhibition of Coagulation factor X				Bioorg Med Chem Lett 12: 2043-6 (2002) BindingDB Entry DOI: 10.7270/Q2PZ584G
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140363 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES CN(C)Cc1nccn1-c1ccc(NC(=O)c2cc(C)nn2-c2ccc3cc(Cl)ccc3c2)c(F)c1 Show InChI InChI=1S/C27H24ClFN6O/c1-17-12-25(35(32-17)22-7-5-18-13-20(28)6-4-19(18)14-22)27(36)31-24-9-8-21(15-23(24)29)34-11-10-30-26(34)16-33(2)3/h4-15H,16H2,1-3H3,(H,31,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140384 (2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)-c2ccccc2S(N)(=O)=O)n(n1)-c1cc2ccccc2cc1S(C)(=O)=O Show InChI InChI=1S/C28H23FN4O5S2/c1-17-13-25(33(32-17)24-15-18-7-3-4-8-19(18)16-27(24)39(2,35)36)28(34)31-23-12-11-20(14-22(23)29)21-9-5-6-10-26(21)40(30,37)38/h3-16H,1-2H3,(H,31,34)(H2,30,37,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140387 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)N2CCCCC2=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C26H23ClN4O2/c1-17-14-24(31(29-17)23-10-6-18-15-20(27)7-5-19(18)16-23)26(33)28-21-8-11-22(12-9-21)30-13-3-2-4-25(30)32/h5-12,14-16H,2-4,13H2,1H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115936 ((E)-3-(1-Amino-isoquinolin-7-yl)-2-fluoro-but-2-en...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1Br)-c1ccccc1S(N)(=O)=O)c1ccc2ccnc(N)c2c1 Show InChI InChI=1S/C25H20BrFN4O3S/c1-14(16-7-6-15-10-11-30-24(28)19(15)12-16)23(27)25(32)31-21-9-8-17(13-20(21)26)18-4-2-3-5-22(18)35(29,33)34/h2-13H,1H3,(H2,28,30)(H,31,32)(H2,29,33,34)/b23-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound towards Coagulation factor X				Bioorg Med Chem Lett 12: 2043-6 (2002) BindingDB Entry DOI: 10.7270/Q2PZ584G
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50249295 (CHEMBL471725 | N-(5-chloropyridin-2-yl)-2-(4-(N,N-...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H20ClN5O2/c1-28(2)20(24)14-7-9-15(10-8-14)21(29)26-18-6-4-3-5-17(18)22(30)27-19-12-11-16(23)13-25-19/h3-13,24H,1-2H3,(H,26,29)(H,25,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140377 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(C)(=O)=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C28H22ClN3O3S/c1-18-15-26(32(31-18)24-14-10-20-16-22(29)11-7-21(20)17-24)28(33)30-23-12-8-19(9-13-23)25-5-3-4-6-27(25)36(2,34)35/h3-17H,1-2H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140386 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES CN(C)Cc1ccccc1-c1ccc(NC(=O)c2cc(C)nn2-c2ccc3cc(Cl)ccc3c2)c(F)c1 Show InChI InChI=1S/C30H26ClFN4O/c1-19-14-29(36(34-19)25-12-9-20-15-24(31)11-8-21(20)16-25)30(37)33-28-13-10-22(17-27(28)32)26-7-5-4-6-23(26)18-35(2)3/h4-17H,18H2,1-3H3,(H,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50115935 ((E)-3-(1-Amino-isoquinolin-7-yl)-2-fluoro-but-2-en...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)c1ccc2ccnc(N)c2c1 Show InChI InChI=1S/C25H20F2N4O3S/c1-14(16-7-6-15-10-11-30-24(28)19(15)12-16)23(27)25(32)31-21-9-8-17(13-20(21)26)18-4-2-3-5-22(18)35(29,33)34/h2-13H,1H3,(H2,28,30)(H,31,32)(H2,29,33,34)/b23-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity of the compound towards Coagulation factor X				Bioorg Med Chem Lett 12: 2043-6 (2002) BindingDB Entry DOI: 10.7270/Q2PZ584G
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140367 (2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)-c2ccccc2S(C)(=O)=O)n(n1)-c1cc2ccccc2cc1S(C)(=O)=O Show InChI InChI=1S/C29H24FN3O5S2/c1-18-14-26(33(32-18)25-16-19-8-4-5-9-20(19)17-28(25)40(3,37)38)29(34)31-24-13-12-21(15-23(24)30)22-10-6-7-11-27(22)39(2,35)36/h4-17H,1-3H3,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140375 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES CN(C)Cc1ccccc1-c1ccc(NC(=O)c2cc(C)nn2-c2ccc3cc(Cl)ccc3c2)cc1 Show InChI InChI=1S/C30H27ClN4O/c1-20-16-29(35(33-20)27-15-11-22-17-25(31)12-8-23(22)18-27)30(36)32-26-13-9-21(10-14-26)28-7-5-4-6-24(28)19-34(2)3/h4-18H,19H2,1-3H3,(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140382 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)C(=O)N2CCCC2)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C26H23ClN4O2/c1-17-14-24(31(29-17)23-11-7-19-15-21(27)8-4-20(19)16-23)25(32)28-22-9-5-18(6-10-22)26(33)30-12-2-3-13-30/h4-11,14-16H,2-3,12-13H2,1H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140356 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)-c2ccccc2S(C)(=O)=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C28H21ClFN3O3S/c1-17-13-26(33(32-17)22-11-8-18-14-21(29)10-7-19(18)15-22)28(34)31-25-12-9-20(16-24(25)30)23-5-3-4-6-27(23)37(2,35)36/h3-16H,1-2H3,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50144092 (CHEMBL294121 | [4-(5-Chloro-1H-indole-2-sulfonyl)-...) Show SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1 |c:4| Show InChI InChI=1S/C23H24ClN5O3S/c1-27-9-8-25-22(27)16-2-4-17(5-3-16)23(30)28-10-12-29(13-11-28)33(31,32)21-15-18-14-19(24)6-7-20(18)26-21/h2-7,14-15,26H,8-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity of the compound against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140366 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cn2)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C26H20ClN5O3S/c1-16-12-23(32(31-16)21-10-7-17-13-20(27)9-6-18(17)14-21)26(33)30-25-11-8-19(15-29-25)22-4-2-3-5-24(22)36(28,34)35/h2-15H,1H3,(H2,28,34,35)(H,29,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140360 (2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...) Show SMILES CN(C)Cc1ccccc1-c1ccc(NC(=O)c2cc(C)nn2-c2cc3ccccc3cc2S(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C31H29FN4O3S/c1-20-15-29(36(34-20)28-17-21-9-5-6-10-22(21)18-30(28)40(4,38)39)31(37)33-27-14-13-23(16-26(27)32)25-12-8-7-11-24(25)19-35(2)3/h5-18H,19H2,1-4H3,(H,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140380 (2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)-c2ccccc2CN)n(n1)-c1cc2ccccc2cc1F Show InChI InChI=1S/C28H22F2N4O/c1-17-12-27(34(33-17)26-15-19-7-3-2-6-18(19)13-24(26)30)28(35)32-25-11-10-20(14-23(25)29)22-9-5-4-8-21(22)16-31/h2-15H,16,31H2,1H3,(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140381 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ncc(cn2)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C25H19ClN6O3S/c1-15-10-22(32(31-15)20-9-7-16-11-19(26)8-6-17(16)12-20)24(33)30-25-28-13-18(14-29-25)21-4-2-3-5-23(21)36(27,34)35/h2-14H,1H3,(H2,27,34,35)(H,28,29,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140397 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES CN(C)Cc1nccn1-c1ccc(NC(=O)c2cc(C)nn2-c2ccc3cc(Cl)ccc3c2)cc1 Show InChI InChI=1S/C27H25ClN6O/c1-18-14-25(34(31-18)24-9-5-19-15-21(28)6-4-20(19)16-24)27(35)30-22-7-10-23(11-8-22)33-13-12-29-26(33)17-32(2)3/h4-16H,17H2,1-3H3,(H,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140352 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)-n2ccnc2C)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C25H20ClN5O/c1-16-13-24(31(29-16)23-8-4-18-14-20(26)5-3-19(18)15-23)25(32)28-21-6-9-22(10-7-21)30-12-11-27-17(30)2/h3-15H,1-2H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140401 (2-(3-Methanesulfonyl-naphthalen-2-yl)-5-methyl-2H-...) Show SMILES CN(C)Cc1nccn1-c1ccc(NC(=O)c2cc(C)nn2-c2cc3ccccc3cc2S(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C28H27FN6O3S/c1-18-13-25(35(32-18)24-14-19-7-5-6-8-20(19)15-26(24)39(4,37)38)28(36)31-23-10-9-21(16-22(23)29)34-12-11-30-27(34)17-33(2)3/h5-16H,17H2,1-4H3,(H,31,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity against Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50140369 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C27H20ClFN4O3S/c1-16-12-25(33(32-16)21-10-7-17-13-20(28)9-6-18(17)14-21)27(34)31-24-11-8-19(15-23(24)29)22-4-2-3-5-26(22)37(30,35)36/h2-15H,1H3,(H,31,34)(H2,30,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193861 (5-chloro-N-(5-chloro-pyridin-2-yl)-2-[4-(N,N-dimet...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C22H19Cl2N5O2/c1-29(2)20(25)13-3-5-14(6-4-13)21(30)27-18-9-7-15(23)11-17(18)22(31)28-19-10-8-16(24)12-26-19/h3-12,25H,1-2H3,(H,27,30)(H,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193849 (CHEMBL219106 | N-(2-(5-chloropyridin-2-ylcarbamoyl...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2N2CCCCC2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C28H31ClN6O3/c1-34(2)26(30)18-7-10-21(24(15-18)35-13-5-4-6-14-35)27(36)32-23-11-9-20(38-3)16-22(23)28(37)33-25-12-8-19(29)17-31-25/h7-12,15-17,30H,4-6,13-14H2,1-3H3,(H,32,36)(H,31,33,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50249120 (CHEMBL472967 | N-(4-chloro-2-(5-chloropyridin-2-yl...) Show SMILES CN(C)C(=N)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(F)c1 Show InChI InChI=1S/C22H18Cl2FN5O2/c1-30(2)20(26)12-3-6-15(17(25)9-12)21(31)28-18-7-4-13(23)10-16(18)22(32)29-19-8-5-14(24)11-27-19/h3-11,26H,1-2H3,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50249298 (BEVYXXA | CHEMBL512351 | N-(5-chloropyridin-2-yl)-...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H22ClN5O3/c1-29(2)21(25)14-4-6-15(7-5-14)22(30)27-19-10-9-17(32-3)12-18(19)23(31)28-20-11-8-16(24)13-26-20/h4-13,25H,1-3H3,(H,27,30)(H,26,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50249423 (CHEMBL515919 | N-(2-(5-chloropyridin-2-ylcarbamoyl...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2F)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C23H21ClFN5O3/c1-30(2)21(26)13-4-7-16(18(25)10-13)22(31)28-19-8-6-15(33-3)11-17(19)23(32)29-20-9-5-14(24)12-27-20/h4-12,26H,1-3H3,(H,28,31)(H,27,29,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193850 (2-(3-(5-chloropyridin-2-ylcarbamoyl)-4-(4-(N,N-dim...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1ccc(OCC(O)=O)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C24H22ClN5O5/c1-30(2)22(26)14-3-5-15(6-4-14)23(33)28-19-9-8-17(35-13-21(31)32)11-18(19)24(34)29-20-10-7-16(25)12-27-20/h3-12,26H,13H2,1-2H3,(H,28,33)(H,31,32)(H,27,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193842 (1-(2-(2-(5-chloropyridin-2-ylcarbamoyl)-4-methoxyp...) Show SMILES COc1ccc(NC(=O)c2ccc(cc2N2CCC(CC2)C(O)=O)C(=N)N(C)C)c(c1)C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C29H31ClN6O5/c1-35(2)26(31)18-4-7-21(24(14-18)36-12-10-17(11-13-36)29(39)40)27(37)33-23-8-6-20(41-3)15-22(23)28(38)34-25-9-5-19(30)16-32-25/h4-9,14-17,31H,10-13H2,1-3H3,(H,33,37)(H,39,40)(H,32,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50113591 ((E)-3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoi...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N Show InChI InChI=1S/C23H20F2N4O3S/c1-13(14-5-4-6-16(11-14)22(26)27)21(25)23(30)29-19-10-9-15(12-18(19)24)17-7-2-3-8-20(17)33(28,31)32/h2-12H,1H3,(H3,26,27)(H,29,30)(H2,28,31,32)/b21-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against factor Xa				Bioorg Med Chem Lett 12: 1511-5 (2002) BindingDB Entry DOI: 10.7270/Q2P84B6X
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50113591 ((E)-3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoi...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N Show InChI InChI=1S/C23H20F2N4O3S/c1-13(14-5-4-6-16(11-14)22(26)27)21(25)23(30)29-19-10-9-15(12-18(19)24)17-7-2-3-8-20(17)33(28,31)32/h2-12H,1H3,(H3,26,27)(H,29,30)(H2,28,31,32)/b21-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration to coagulation factor X				Bioorg Med Chem Lett 13: 297-300 (2002) BindingDB Entry DOI: 10.7270/Q2XD112T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50249166 (2-(azetidin-1-yl)-N-(4-chloro-2-(5-chloropyridin-2...) Show SMILES CN(C)C(=N)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(c1)N1CCC1 Show InChI InChI=1S/C25H24Cl2N6O2/c1-32(2)23(28)15-4-7-18(21(12-15)33-10-3-11-33)24(34)30-20-8-5-16(26)13-19(20)25(35)31-22-9-6-17(27)14-29-22/h4-9,12-14,28H,3,10-11H2,1-2H3,(H,30,34)(H,29,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50113590 ((E)-3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoi...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1Br)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N Show InChI InChI=1S/C23H20BrFN4O3S/c1-13(14-5-4-6-16(11-14)22(26)27)21(25)23(30)29-19-10-9-15(12-18(19)24)17-7-2-3-8-20(17)33(28,31)32/h2-12H,1H3,(H3,26,27)(H,29,30)(H2,28,31,32)/b21-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration to coagulation factor X				Bioorg Med Chem Lett 13: 297-300 (2002) BindingDB Entry DOI: 10.7270/Q2XD112T
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50113586 ((E)-3-(3-Carbamimidoyl-phenyl)-2-fluoro-but-2-enoi...) Show SMILES C\C(=C(/F)C(=O)Nc1ccc(cc1Cl)-c1ccccc1S(N)(=O)=O)c1cccc(c1)C(N)=N Show InChI InChI=1S/C23H20ClFN4O3S/c1-13(14-5-4-6-16(11-14)22(26)27)21(25)23(30)29-19-10-9-15(12-18(19)24)17-7-2-3-8-20(17)33(28,31)32/h2-12H,1H3,(H3,26,27)(H,29,30)(H2,28,31,32)/b21-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against factor Xa				Bioorg Med Chem Lett 12: 1511-5 (2002) BindingDB Entry DOI: 10.7270/Q2P84B6X
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50249119 (5-chloro-N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimeth...) Show SMILES CCN(C)c1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1ccc(cc1)C(=N)N(C)C Show InChI InChI=1S/C25H26Cl2N6O2/c1-5-33(4)20-13-18(27)12-19(25(35)30-21-11-10-17(26)14-29-21)22(20)31-24(34)16-8-6-15(7-9-16)23(28)32(2)3/h6-14,28H,5H2,1-4H3,(H,31,34)(H,29,30,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50249118 (5-chloro-N-(5-chloropyridin-2-yl)-3-(dimethylamino...) Show SMILES CN(C)C(=N)c1ccc(cc1)C(=O)Nc1c(cc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)N(C)C Show InChI InChI=1S/C24H24Cl2N6O2/c1-31(2)19-12-17(26)11-18(24(34)29-20-10-9-16(25)13-28-20)21(19)30-23(33)15-7-5-14(6-8-15)22(27)32(3)4/h5-13,27H,1-4H3,(H,30,33)(H,28,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50249117 (5-chloro-N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimeth...) Show SMILES CC(C)Oc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1ccc(cc1)C(=N)N(C)C Show InChI InChI=1S/C25H25Cl2N5O3/c1-14(2)35-20-12-18(27)11-19(25(34)30-21-10-9-17(26)13-29-21)22(20)31-24(33)16-7-5-15(6-8-16)23(28)32(3)4/h5-14,28H,1-4H3,(H,31,33)(H,29,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair

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