Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM35536 (symmetric dicoumarol analogue, 12) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Manchester | Assay Description Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa... | J Med Chem 52: 7142-56 (2009) Article DOI: 10.1021/jm9011609 BindingDB Entry DOI: 10.7270/Q2222S40 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM14774 (3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem N.V. Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE4B1 activity assessed as residual cAMP concentration by HTRF assay | Bioorg Med Chem Lett 24: 4594-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.016 BindingDB Entry DOI: 10.7270/Q21C1ZFH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM35534 (symmetric dicoumarol analogue, 10) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Manchester | Assay Description Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa... | J Med Chem 52: 7142-56 (2009) Article DOI: 10.1021/jm9011609 BindingDB Entry DOI: 10.7270/Q2222S40 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
NAD(P)H dehydrogenase [quinone] 1 (Homo sapiens (Human)) | BDBM35537 (symmetric dicoumarol analogue, 13) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.420 | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Manchester | Assay Description Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa... | J Med Chem 52: 7142-56 (2009) Article DOI: 10.1021/jm9011609 BindingDB Entry DOI: 10.7270/Q2222S40 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human)) | BDBM50125935 ((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Eindhoven University of Technology Curated by ChEMBL | Assay Description Inhibition of human CYP11B1 expressed in chinese hamster V79 cells | J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM14774 (3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem N.V. Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE4D2 activity assessed as residual cAMP concentration by HTRF assay | Bioorg Med Chem Lett 24: 4594-7 (2014) Article DOI: 10.1016/j.bmcl.2014.07.016 BindingDB Entry DOI: 10.7270/Q21C1ZFH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087138 (CHEMBL3426730) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087130 (CHEMBL3426625) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087127 (CHEMBL3426637) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087126 (CHEMBL3426639) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087125 (CHEMBL3426640) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087275 (CHEMBL3426644) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087270 (CHEMBL3426645) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087122 (CHEMBL3426647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087121 (CHEMBL3426723) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087170 (CHEMBL3426724) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087169 (CHEMBL3426725) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087167 (CHEMBL3426727) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087166 (CHEMBL3426728) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087165 (CHEMBL3426729) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087131 (CHEMBL3426624) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087137 (CHEMBL3426731) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087136 (CHEMBL3426732) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087122 (CHEMBL3426647) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087121 (CHEMBL3426723) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087170 (CHEMBL3426724) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087134 (CHEMBL3426620) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50087130 (CHEMBL3426625) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK1 expressed in insect cells using long S6 kinase peptide as substrate by radiometric assay in presence ... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50087131 (CHEMBL3426624) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK1 expressed in insect cells using long S6 kinase peptide as substrate by radiometric assay in presence ... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50087132 (CHEMBL3426623) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK1 expressed in insect cells using long S6 kinase peptide as substrate by radiometric assay in presence ... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 1 (Homo sapiens (Human)) | BDBM50087133 (CHEMBL3426622) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK1 expressed in insect cells using long S6 kinase peptide as substrate by radiometric assay in presence ... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087166 (CHEMBL3426728) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087169 (CHEMBL3426725) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087132 (CHEMBL3426623) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087133 (CHEMBL3426622) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50442811 (CHEMBL2440742) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem N.V. Curated by ChEMBL | Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay | Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087124 (CHEMBL3426641) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087168 (CHEMBL3426726) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087167 (CHEMBL3426727) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087168 (CHEMBL3426726) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087123 (CHEMBL3426642) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087126 (CHEMBL3426639) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50442814 (CHEMBL2440745) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem N.V. Curated by ChEMBL | Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay | Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50442812 (CHEMBL2440735) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem N.V. Curated by ChEMBL | Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay | Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50442809 (CHEMBL2440733) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem N.V. Curated by ChEMBL | Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay | Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087443 (CHEMBL3426627) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087129 (CHEMBL3426633) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM50125935 ((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Eindhoven University of Technology Curated by ChEMBL | Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells | J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human)) | BDBM50307231 (1-(4-Cyanobenzyl)-5-phenyl-1H-imidazole | CHEMBL59...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Eindhoven University of Technology Curated by ChEMBL | Assay Description Inhibition of human CYP11B2 expressed in chinese hamster V79 cells | J Med Chem 53: 1712-25 (2010) Article DOI: 10.1021/jm901356d BindingDB Entry DOI: 10.7270/Q2XS5VGF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 (Homo sapiens (Human)) | BDBM50087441 (CHEMBL3426629) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Agoralaan Abis Curated by ChEMBL | Assay Description Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr... | J Med Chem 58: 4309-24 (2015) Article DOI: 10.1021/acs.jmedchem.5b00308 BindingDB Entry DOI: 10.7270/Q2H41T4R | |||||||||||
More data for this Ligand-Target Pair |
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