Compile Data Set for Download or QSAR

Found 142 hits with Last Name = 'linton' and Initial = 'o'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203582 ((8S,11R,13S,14S,17S)-11-(4-(diphenylphosphoryl)phe...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)P(=O)(c1ccccc1)c1ccccc1 |c:18,t:11| Show InChI InChI=1S/C39H39O3P/c1-3-23-39(41)24-22-36-34-20-16-28-25-29(40)17-21-33(28)37(34)35(26-38(36,39)2)27-14-18-32(19-15-27)43(42,30-10-6-4-7-11-30)31-12-8-5-9-13-31/h4-15,18-19,25,34-36,41H,16-17,20-22,24,26H2,1-2H3/t34-,35+,36-,38-,39-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203580 (CHEMBL250751 | diethyl 4-((8S,11R,13S,14S,17S)-17-...) Show SMILES CCOP(=O)(OCC)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:31,38| Show InChI InChI=1S/C31H39O5P/c1-5-17-31(33)18-16-28-26-14-10-22-19-23(32)11-15-25(22)29(26)27(20-30(28,31)4)21-8-12-24(13-9-21)37(34,35-6-2)36-7-3/h8-9,12-13,19,26-28,33H,6-7,10-11,14-16,18,20H2,1-4H3/t26-,27+,28-,30-,31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203579 (CHEMBL250750 | diethyl 4-((8S,11R,13S,14S,17R)-17-...) Show SMILES CCOP(=O)(OCC)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)CC=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:31,38| Show InChI InChI=1S/C31H41O5P/c1-5-17-31(33)18-16-28-26-14-10-22-19-23(32)11-15-25(22)29(26)27(20-30(28,31)4)21-8-12-24(13-9-21)37(34,35-6-2)36-7-3/h5,8-9,12-13,19,26-28,33H,1,6-7,10-11,14-18,20H2,2-4H3/t26-,27+,28-,30-,31-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203577 ((8S,11R,13S,14S,17R)-17-allyl-11-(4-(diphenylphosp...) Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@]2(O)CC=C)c1ccc(cc1)P(=O)(c1ccccc1)c1ccccc1 |c:4,10| Show InChI InChI=1S/C39H41O3P/c1-3-23-39(41)24-22-36-34-20-16-28-25-29(40)17-21-33(28)37(34)35(26-38(36,39)2)27-14-18-32(19-15-27)43(42,30-10-6-4-7-11-30)31-12-8-5-9-13-31/h3-15,18-19,25,34-36,41H,1,16-17,20-24,26H2,2H3/t34-,35+,36-,38-,39-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203584 ((8S,11R,13S,14S,17S)-11-(4-(diphenylphosphoryl)phe...) Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@@]2(O)c1ccccc1)c1ccc(cc1)P(=O)(c1ccccc1)c1ccccc1 |c:4,10| Show InChI InChI=1S/C42H41O3P/c1-41-28-38(29-17-21-35(22-18-29)46(45,33-13-7-3-8-14-33)34-15-9-4-10-16-34)40-36-24-20-32(43)27-30(36)19-23-37(40)39(41)25-26-42(41,44)31-11-5-2-6-12-31/h2-18,21-22,27,37-39,44H,19-20,23-26,28H2,1H3/t37-,38+,39-,41-,42+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203586 (CHEMBL400047 | diethyl {4-[(2R,10'S,11'S,15'S,17'R...) Show SMILES CCOP(=O)(OCC)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C32H41O5P/c1-5-36-38(34,37-6-2)25-11-7-22(8-12-25)28-20-31(4)29(15-17-32(31)21(3)16-18-35-32)27-13-9-23-19-24(33)10-14-26(23)30(27)28/h7-8,11-12,19,27-29H,3,5-6,9-10,13-18,20H2,1-2,4H3/t27-,28+,29-,31-,32+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	56.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203578 (CHEMBL413806 | ethyl methyl({4-[(2R,10'S,11'S,15'S...) Show SMILES CCOP(C)(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:31,38| Show InChI InChI=1S/C31H39O4P/c1-5-35-36(4,33)24-10-6-21(7-11-24)27-19-30(3)28(14-16-31(30)20(2)15-17-34-31)26-12-8-22-18-23(32)9-13-25(22)29(26)27/h6-7,10-11,18,26-28H,2,5,8-9,12-17,19H2,1,3-4H3/t26-,27+,28-,30-,31+,36?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	59.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203583 (CHEMBL250949 | ethoxy({4-[(2R,10'S,11'S,15'S,17'R)...) Show SMILES CCOP(O)(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:31,38| Show InChI InChI=1S/C30H37O5P/c1-4-35-36(32,33)23-9-5-20(6-10-23)26-18-29(3)27(13-15-30(29)19(2)14-16-34-30)25-11-7-21-17-22(31)8-12-24(21)28(25)26/h5-6,9-10,17,25-27H,2,4,7-8,11-16,18H2,1,3H3,(H,32,33)/t25-,26+,27-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203581 (CHEMBL401477 | methyl({4-[(2R,10'S,11'S,15'S,17'R)...) Show SMILES C[C@]12C[C@@H](C3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]21OCCC1=C)c1ccc(cc1)P(C)(O)=O |c:4,10| Show InChI InChI=1S/C29H35O4P/c1-18-13-15-33-29(18)14-12-26-24-10-6-20-16-21(30)7-11-23(20)27(24)25(17-28(26,29)2)19-4-8-22(9-5-19)34(3,31)32/h4-5,8-9,16,24-26H,1,6-7,10-15,17H2,2-3H3,(H,31,32)/t24-,25+,26-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	0.0540	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50206106 ((8S,11R,13S,14R)-11-(4-dimethylamino-phenyl)-17-(4...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(F)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |r,t:33,40| Show InChI InChI=1S/C33H34FNO3/c1-32-19-28(22-6-10-25(11-7-22)35(2)3)30-27-13-12-26(36)18-23(27)20-38-31(30)29(32)15-17-33(32,37)16-14-21-4-8-24(34)9-5-21/h4-11,18,28-29,31,37H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50295639 ((1R,3S,3aR,3bS,10R)-10-(4-Dimethylamino-phenyl)-1-...) Show SMILES CN(C)c1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@@]2(O)C(C)=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:27,34| Show InChI InChI=1S/C29H37NO3/c1-18(2)29(32)15-14-25-24-12-8-20-16-22(31)11-13-23(20)26(24)27(33-17-28(25,29)3)19-6-9-21(10-7-19)30(4)5/h6-7,9-10,16,24-25,27,32H,1,8,11-15,17H2,2-5H3/t24-,25-,27+,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222089 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5-et...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(cc2)C(C)=O)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C31H35NO3/c1-5-28-32-31(19(3)35-28)15-14-27-25-12-10-22-16-23(34)11-13-24(22)29(25)26(17-30(27,31)4)21-8-6-20(7-9-21)18(2)33/h6-9,16,25-27H,3,5,10-15,17H2,1-2,4H3/t25-,26+,27-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222091 ((3S,10'S,11'S,15'S,17'R)-17'-(4-acetylphenyl)-5,15...) Show SMILES CC(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C30H33NO3/c1-17(32)20-5-7-21(8-6-20)26-16-29(4)27(13-14-30(29)18(2)34-19(3)31-30)25-11-9-22-15-23(33)10-12-24(22)28(25)26/h5-8,15,25-27H,2,9-14,16H2,1,3-4H3/t25-,26+,27-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206114 ((8S,11R,13S,14R,17S)-17-(4-chloro-phenylethynyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(Cl)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34ClNO3/c1-32-19-28(22-6-10-25(11-7-22)35(2)3)30-27-13-12-26(36)18-23(27)20-38-31(30)29(32)15-17-33(32,37)16-14-21-4-8-24(34)9-5-21/h4-11,18,28-29,31,37H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222086 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C30H36N2O2/c1-18-30(31-19(2)34-18)15-14-27-25-12-8-21-16-23(33)11-13-24(21)28(25)26(17-29(27,30)3)20-6-9-22(10-7-20)32(4)5/h6-7,9-10,16,25-27H,1,8,11-15,17H2,2-5H3/t25-,26+,27-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206108 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(cc2)C(F)(F)F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C34H34F3NO3/c1-32-19-28(22-6-10-25(11-7-22)38(2)3)30-27-13-12-26(39)18-23(27)20-41-31(30)29(32)15-17-33(32,40)16-14-21-4-8-24(9-5-21)34(35,36)37/h4-11,18,28-29,31,40H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206097 ((8S,11R,13S,14R,17S)-17-(3,5-difluoro-phenylethyny...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cc(F)cc(F)c2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C33H33F2NO3/c1-32-18-28(21-4-6-25(7-5-21)36(2)3)30-27-9-8-26(37)16-22(27)19-39-31(30)29(32)11-13-33(32,38)12-10-20-14-23(34)17-24(35)15-20/h4-7,14-17,28-29,31,38H,8-9,11,13,18-19H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206109 ((8S,11R,13S,14R,17S)-17-(4-bromo-phenylethynyl)-11...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(Br)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34BrNO3/c1-32-19-28(22-6-10-25(11-7-22)35(2)3)30-27-13-12-26(36)18-23(27)20-38-31(30)29(32)15-17-33(32,37)16-14-21-4-8-24(34)9-5-21/h4-11,18,28-29,31,37H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222092 ((3S,10'S,11'S,15'S,17'R)-17'-[4-(dimethylamino)phe...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(cc2)N(C)C)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C31H38N2O2/c1-6-28-32-31(19(2)35-28)16-15-27-25-13-9-21-17-23(34)12-14-24(21)29(25)26(18-30(27,31)3)20-7-10-22(11-8-20)33(4)5/h7-8,10-11,17,25-27H,2,6,9,12-16,18H2,1,3-5H3/t25-,26+,27-,30-,31+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50295646 ((1'S,2R,2'S,6'R,9'R)-9'-[4-(dimethylamino)phenyl]-...) Show SMILES CN(C)c1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:29,36| Show InChI InChI=1S/C30H37NO3/c1-19-14-16-34-30(19)15-13-26-25-11-7-21-17-23(32)10-12-24(21)27(25)28(33-18-29(26,30)2)20-5-8-22(9-6-20)31(3)4/h5-6,8-9,17,25-26,28H,1,7,10-16,18H2,2-4H3/t25-,26-,28+,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222088 ((3S,10'S,11'S,15'S,17'R)-5-ethyl-17'-(3-fluoro-4-m...) Show SMILES CCC1=N[C@]2(CC[C@H]3[C@@H]4CCC5=CC(=O)CCC5=C4[C@H](C[C@]23C)c2ccc(OC)c(F)c2)C(=C)O1 |c:18,t:2,11| Show InChI InChI=1S/C30H34FNO3/c1-5-27-32-30(17(2)35-27)13-12-24-22-9-6-18-14-20(33)8-10-21(18)28(22)23(16-29(24,30)3)19-7-11-26(34-4)25(31)15-19/h7,11,14-15,22-24H,2,5-6,8-10,12-13,16H2,1,3-4H3/t22-,23+,24-,29-,30+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206101 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccc(F)c2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34FNO3/c1-32-19-28(22-7-9-25(10-8-22)35(2)3)30-27-12-11-26(36)18-23(27)20-38-31(30)29(32)14-16-33(32,37)15-13-21-5-4-6-24(34)17-21/h4-10,17-18,28-29,31,37H,11-12,14,16,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206098 ((8S,11R,13S,14R,17S)-17-(2-chloro-phenylethynyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2Cl)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34ClNO3/c1-32-19-27(21-8-10-24(11-9-21)35(2)3)30-26-13-12-25(36)18-23(26)20-38-31(30)28(32)15-17-33(32,37)16-14-22-6-4-5-7-29(22)34/h4-11,18,27-28,31,37H,12-13,15,17,19-20H2,1-3H3/t27-,28+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206100 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34FNO3/c1-32-19-27(21-8-10-24(11-9-21)35(2)3)30-26-13-12-25(36)18-23(26)20-38-31(30)28(32)15-17-33(32,37)16-14-22-6-4-5-7-29(22)34/h4-11,18,27-28,31,37H,12-13,15,17,19-20H2,1-3H3/t27-,28+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50200660 ((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |r,t:32,39| Show InChI InChI=1S/C33H35NO3/c1-32-20-28(23-9-11-25(12-10-23)34(2)3)30-27-14-13-26(35)19-24(27)21-37-31(30)29(32)16-18-33(32,36)17-15-22-7-5-4-6-8-22/h4-12,19,28-29,31,36H,13-14,16,18,20-21H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 17: 907-10 (2007) Article DOI: 10.1016/j.bmcl.2006.11.062 BindingDB Entry DOI: 10.7270/Q2571CVQ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50200660 ((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |r,t:32,39| Show InChI InChI=1S/C33H35NO3/c1-32-20-28(23-9-11-25(12-10-23)34(2)3)30-27-14-13-26(35)19-24(27)21-37-31(30)29(32)16-18-33(32,36)17-15-22-7-5-4-6-8-22/h4-12,19,28-29,31,36H,13-14,16,18,20-21H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 17: 907-10 (2007) Article DOI: 10.1016/j.bmcl.2006.11.062 BindingDB Entry DOI: 10.7270/Q2571CVQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced transcription after 16 hrs by glucocor...				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced GRE-linked luciferase reporter gene ac...				Bioorg Med Chem Lett 17: 907-10 (2007) Article DOI: 10.1016/j.bmcl.2006.11.062 BindingDB Entry DOI: 10.7270/Q2571CVQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50203578 (CHEMBL413806 | ethyl methyl({4-[(2R,10'S,11'S,15'S...) Show SMILES CCOP(C)(=O)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:31,38| Show InChI InChI=1S/C31H39O4P/c1-5-35-36(4,33)24-10-6-21(7-11-24)27-19-30(3)28(14-16-31(30)20(2)15-17-34-31)26-12-8-22-18-23(32)9-13-25(22)29(26)27/h6-7,10-11,18,26-28H,2,5,8-9,12-17,19H2,1,3-4H3/t26-,27+,28-,30-,31+,36?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47 cells assessed as blockade of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206115 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccsc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:31,38| Show InChI InChI=1S/C31H33NO3S/c1-30-17-26(21-4-6-23(7-5-21)32(2)3)28-25-9-8-24(33)16-22(25)18-35-29(28)27(30)11-14-31(30,34)13-10-20-12-15-36-19-20/h4-7,12,15-16,19,26-27,29,34H,8-9,11,14,17-18H2,1-3H3/t26-,27+,29+,30+,31+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206107 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(C)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C34H37NO3/c1-22-5-7-23(8-6-22)15-17-34(37)18-16-30-32-31(28-14-13-27(36)19-25(28)21-38-32)29(20-33(30,34)2)24-9-11-26(12-10-24)35(3)4/h5-12,19,29-30,32,37H,13-14,16,18,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development L.L.C. Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47 cells assessed as blockade of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 17: 1471-4 (2007) Article DOI: 10.1016/j.bmcl.2006.10.003 BindingDB Entry DOI: 10.7270/Q2PN96GJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Progesterone receptor (Homo sapiens (Human))	BDBM50206102 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccc(c2)C(F)(F)F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C34H34F3NO3/c1-32-19-28(22-7-9-25(10-8-22)38(2)3)30-27-12-11-26(39)18-23(27)20-41-31(30)29(32)14-16-33(32,40)15-13-21-5-4-6-24(17-21)34(35,36)37/h4-10,17-18,28-29,31,40H,11-12,14,16,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206111 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccc(C)c2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C34H37NO3/c1-22-6-5-7-23(18-22)14-16-34(37)17-15-30-32-31(28-13-12-27(36)19-25(28)21-38-32)29(20-33(30,34)2)24-8-10-26(11-9-24)35(3)4/h5-11,18-19,29-30,32,37H,12-13,15,17,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206104 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2C(F)(F)F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C34H34F3NO3/c1-32-19-27(21-8-10-24(11-9-21)38(2)3)30-26-13-12-25(39)18-23(26)20-41-31(30)29(32)15-17-33(32,40)16-14-22-6-4-5-7-28(22)34(35,36)37/h4-11,18,27,29,31,40H,12-13,15,17,19-20H2,1-3H3/t27-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206117 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES COc1ccc(cc1)C#C[C@]1(O)CC[C@H]2[C@@H]3OCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C |c:26,t:19| Show InChI InChI=1S/C34H37NO4/c1-33-20-29(23-7-9-25(10-8-23)35(2)3)31-28-14-11-26(36)19-24(28)21-39-32(31)30(33)16-18-34(33,37)17-15-22-5-12-27(38-4)13-6-22/h5-10,12-13,19,29-30,32,37H,11,14,16,18,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50295637 ((1R,3S,3aR,3bS,10R)-1-Hydroxy-1-isopropenyl-12a-me...) Show SMILES CSc1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@@]2(O)C(C)=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:26,33| Show InChI InChI=1S/C28H34O3S/c1-17(2)28(30)14-13-24-23-11-7-19-15-20(29)8-12-22(19)25(23)26(31-16-27(24,28)3)18-5-9-21(32-4)10-6-18/h5-6,9-10,15,23-24,26,30H,1,7-8,11-14,16H2,2-4H3/t23-,24-,26+,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206113 (4-[(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(cc2)C#N)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C34H34N2O3/c1-33-19-29(24-8-10-26(11-9-24)36(2)3)31-28-13-12-27(37)18-25(28)21-39-32(31)30(33)15-17-34(33,38)16-14-22-4-6-23(20-35)7-5-22/h4-11,18,29-30,32,38H,12-13,15,17,19,21H2,1-3H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50222087 ((3S,10'S,11'S,15'S,17'R)-17'-(3-fluoro-4-methoxyph...) Show SMILES COc1ccc(cc1F)[C@H]1C[C@@]2(C)[C@@H](CC[C@]22N=C(C)OC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |t:19,29,36| Show InChI InChI=1S/C29H32FNO3/c1-16-29(31-17(2)34-16)12-11-24-22-8-5-18-13-20(32)7-9-21(18)27(22)23(15-28(24,29)3)19-6-10-26(33-4)25(30)14-19/h6,10,13-14,22-24H,1,5,7-9,11-12,15H2,2-4H3/t22-,23+,24-,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor expressed in human T47D cells assessed as inhibition of promegestone-induced alkaline phosphatase activi...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50206099 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2C)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C34H37NO3/c1-22-7-5-6-8-23(22)15-17-34(37)18-16-30-32-31(28-14-13-27(36)19-25(28)21-38-32)29(20-33(30,34)2)24-9-11-26(12-10-24)35(3)4/h5-12,19,29-30,32,37H,13-14,16,18,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
RTI International Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor expressed in A549 cells assessed as inhibition of corticoid-induced gene transcription by luciferase r...				Bioorg Med Chem Lett 17: 5754-7 (2007) Article DOI: 10.1016/j.bmcl.2007.08.064 BindingDB Entry DOI: 10.7270/Q2Z03905
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50295638 ((1S,3S,3aR,3bS,10R)-1-Hydroxy-12a-methyl-10-(4-met...) Show SMILES CSc1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@@]2(O)C(F)(F)C(F)(F)F)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:30,37| Show InChI InChI=1S/C27H29F5O3S/c1-24-14-35-23(15-3-7-18(36-2)8-4-15)22-19-10-6-17(33)13-16(19)5-9-20(22)21(24)11-12-25(24,34)26(28,29)27(30,31)32/h3-4,7-8,13,20-21,23,34H,5-6,9-12,14H2,1-2H3/t20-,21-,23+,24-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced transcription after 16 hrs by glucocor...				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50295645 ((1'S,2R,2'S,6'R,9'R)-9'-(4-methoxyphenyl)-6'-methy...) Show SMILES COc1ccc(cc1)[C@H]1OC[C@@]2(C)[C@@H](CC[C@]22OCCC2=C)[C@@H]2CCC3=CC(=O)CCC3=C12 |r,t:28,35| Show InChI InChI=1S/C29H34O4/c1-18-13-15-33-29(18)14-12-25-24-10-6-20-16-21(30)7-11-23(20)26(24)27(32-17-28(25,29)2)19-4-8-22(31-3)9-5-19/h4-5,8-9,16,24-25,27H,1,6-7,10-15,17H2,2-3H3/t24-,25-,27+,28-,29+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity				Bioorg Med Chem Lett 19: 3977-80 (2009) Article DOI: 10.1016/j.bmcl.2009.01.095 BindingDB Entry DOI: 10.7270/Q29Z95VR
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50200655 ((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3OCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C |r,c:18,t:11| Show InChI InChI=1S/C28H33NO3/c1-5-13-28(31)14-12-24-26-25(22-11-10-21(30)15-19(22)17-32-26)23(16-27(24,28)2)18-6-8-20(9-7-18)29(3)4/h6-9,15,23-24,26,31H,10-12,14,16-17H2,1-4H3/t23-,24+,26+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair

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