Found 117 hits with Last Name = 'marzo' and Initial = 'md' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50297444
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC1 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC4 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC11 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC5 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC10 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC7 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC2 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC9 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50278220
(CHEMBL471042 | N-hydroxy-3-(4-((4-nitrobenzyloxyim...)Show SMILES ONC(=O)\C=C\c1ccc(\C=N\OCc2ccc(cc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H15N3O5/c21-17(19-22)10-7-13-1-3-14(4-2-13)11-18-25-12-15-5-8-16(9-6-15)20(23)24/h1-11,22H,12H2,(H,19,21)/b10-7+,18-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC1 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50278221
(CHEMBL471043 | methyl 4-((4-(3-(hydroxyamino)-3-ox...)Show SMILES COC(=O)c1ccc(CO\N=C\c2ccc(\C=C\C(=O)NO)cc2)cc1 Show InChI InChI=1S/C19H18N2O5/c1-25-19(23)17-9-6-16(7-10-17)13-26-20-12-15-4-2-14(3-5-15)8-11-18(22)21-24/h2-12,24H,13H2,1H3,(H,21,22)/b11-8+,20-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50278220
(CHEMBL471042 | N-hydroxy-3-(4-((4-nitrobenzyloxyim...)Show SMILES ONC(=O)\C=C\c1ccc(\C=N\OCc2ccc(cc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H15N3O5/c21-17(19-22)10-7-13-1-3-14(4-2-13)11-18-25-12-15-5-8-16(9-6-15)20(23)24/h1-11,22H,12H2,(H,19,21)/b10-7+,18-11+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50278344
(CHEMBL470843 | N-hydroxy-3-(4-(5-(morpholinomethyl...)Show InChI InChI=1S/C17H19N3O4/c21-17(18-22)6-3-13-1-4-14(5-2-13)16-11-15(24-19-16)12-20-7-9-23-10-8-20/h1-6,11,22H,7-10,12H2,(H,18,21)/b6-3+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC1 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC5 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC9 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50278220
(CHEMBL471042 | N-hydroxy-3-(4-((4-nitrobenzyloxyim...)Show SMILES ONC(=O)\C=C\c1ccc(\C=N\OCc2ccc(cc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C17H15N3O5/c21-17(19-22)10-7-13-1-3-14(4-2-13)11-18-25-12-15-5-8-16(9-6-15)20(23)24/h1-11,22H,12H2,(H,19,21)/b10-7+,18-11+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50278344
(CHEMBL470843 | N-hydroxy-3-(4-(5-(morpholinomethyl...)Show InChI InChI=1S/C17H19N3O4/c21-17(18-22)6-3-13-1-4-14(5-2-13)16-11-15(24-19-16)12-20-7-9-23-10-8-20/h1-6,11,22H,7-10,12H2,(H,18,21)/b6-3+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 175 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC4 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC4 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC7 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50278222
(CHEMBL472631 | N-hydroxy-3-(4-((2-morpholinoethoxy...)Show InChI InChI=1S/C16H21N3O4/c20-16(18-21)6-5-14-1-3-15(4-2-14)13-17-23-12-9-19-7-10-22-11-8-19/h1-6,13,21H,7-12H2,(H,18,20)/b6-5+,17-13+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 235 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC10 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50297444
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Polyamine deacetylase HDAC10
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC10 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50297448
(CHEMBL564916 | N-(2-aminophenyl)-7,7-di(1H-indol-3...)Show SMILES Nc1ccccc1NC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C29H30N4O/c30-25-13-6-9-16-28(25)33-29(34)17-3-1-2-10-20(23-18-31-26-14-7-4-11-21(23)26)24-19-32-27-15-8-5-12-22(24)27/h4-9,11-16,18-20,31-32H,1-3,10,17,30H2,(H,33,34) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50278222
(CHEMBL472631 | N-hydroxy-3-(4-((2-morpholinoethoxy...)Show InChI InChI=1S/C16H21N3O4/c20-16(18-21)6-5-14-1-3-15(4-2-14)13-17-23-12-9-19-7-10-22-11-8-19/h1-6,13,21H,7-12H2,(H,18,20)/b6-5+,17-13+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 303 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC6 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC5 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC9 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50297444
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50297447
(3-(4-(di(1H-indol-3-yl)methyl)phenyl)-N-hydroxyacr...)Show SMILES ONC(=O)\C=C\c1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C26H21N3O2/c30-25(29-31)14-11-17-9-12-18(13-10-17)26(21-15-27-23-7-3-1-5-19(21)23)22-16-28-24-8-4-2-6-20(22)24/h1-16,26-28,31H,(H,29,30)/b14-11+ | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC11 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC7 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 11
(Homo sapiens (Human)) | BDBM50297444
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27) | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC11 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 3
(Homo sapiens (Human)) | BDBM50297447
(3-(4-(di(1H-indol-3-yl)methyl)phenyl)-N-hydroxyacr...)Show SMILES ONC(=O)\C=C\c1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C26H21N3O2/c30-25(29-31)14-11-17-9-12-18(13-10-17)26(21-15-27-23-7-3-1-5-19(21)23)22-16-28-24-8-4-2-6-20(22)24/h1-16,26-28,31H,(H,29,30)/b14-11+ | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC3 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50297445
(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)Show SMILES COc1cccc2c(c[nH]c12)C(CCCCCC(=O)NO)c1c[nH]c2c(OC)cccc12 Show InChI InChI=1S/C25H29N3O4/c1-31-21-11-6-9-17-19(14-26-24(17)21)16(8-4-3-5-13-23(29)28-30)20-15-27-25-18(20)10-7-12-22(25)32-2/h6-7,9-12,14-16,26-27,30H,3-5,8,13H2,1-2H3,(H,28,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC2 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 7
(Homo sapiens (Human)) | BDBM50297444
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC7 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC2 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50297444
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC5 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50297446
(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccc(cc12)[N+]([O-])=O)c1c[nH]c2ccc(cc12)[N+]([O-])=O Show InChI InChI=1S/C23H23N5O6/c29-23(26-30)5-3-1-2-4-16(19-12-24-21-8-6-14(27(31)32)10-17(19)21)20-13-25-22-9-7-15(28(33)34)11-18(20)22/h6-13,16,24-25,30H,1-5H2,(H,26,29) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50278221
(CHEMBL471043 | methyl 4-((4-(3-(hydroxyamino)-3-ox...)Show SMILES COC(=O)c1ccc(CO\N=C\c2ccc(\C=C\C(=O)NO)cc2)cc1 Show InChI InChI=1S/C19H18N2O5/c1-25-19(23)17-9-6-16(7-10-17)13-26-20-12-15-4-2-14(3-5-15)8-11-18(22)21-24/h2-12,24H,13H2,1H3,(H,21,22)/b11-8+,20-12+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 603 | n/a | n/a | n/a | n/a | n/a | n/a |
R&D Sigma-Tau SpA
Curated by ChEMBL
| Assay Description Inhibition of human HDAC8 |
Bioorg Med Chem Lett 19: 2346-9 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.029 BindingDB Entry DOI: 10.7270/Q2154GX2 |
More data for this Ligand-Target Pair | |
Histone deacetylase 9
(Homo sapiens (Human)) | BDBM50297444
(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)Show SMILES ONC(=O)CCCCCC(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C23H25N3O2/c27-23(26-28)13-3-1-2-8-16(19-14-24-21-11-6-4-9-17(19)21)20-15-25-22-12-7-5-10-18(20)22/h4-7,9-12,14-16,24-25,28H,1-3,8,13H2,(H,26,27) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma-Tau Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human HDAC9 by fluroimetry |
Bioorg Med Chem Lett 19: 2840-3 (2009)
Checked by Author Article DOI: 10.1016/j.bmcl.2009.03.101 BindingDB Entry DOI: 10.7270/Q2PN95PT |
More data for this Ligand-Target Pair | |