Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to human ERG | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301803 (2-((2-chloro-5-fluorophenoxy)methyl)-3-ethyl-6-(pi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 103 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301771 (6-(3-chlorophenethyl)-3-methyl-2-(piperazin-1-yl)p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301772 ((R)-6-(2-methylpiperazin-1-yl)-2-(2-(2-(trifluorom...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 47 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301773 (6-methyl-3-(3-phenoxypropyl)-2-(piperazin-1-yl)pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301774 (3-(3-(2-fluorophenoxy)propyl)-6-methyl-2-(piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 77 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301775 (3-(3-(3-fluorophenoxy)propyl)-6-methyl-2-(piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301776 (3-(3-(4-fluorophenoxy)propyl)-6-methyl-2-(piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301777 (3-(3-(2-chlorophenoxy)propyl)-6-methyl-2-(piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 56 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301778 (3-(3-(3-chlorophenoxy)propyl)-6-methyl-2-(piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 262 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301779 (3-(3-(4-chlorophenoxy)propyl)-6-methyl-2-(piperazi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 899 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301780 (6-methyl-2-((R)-2-methylpiperazin-1-yl)-3-(3-pheno...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 163 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301781 (3-methyl-2-phenethyl-6-(piperazin-1-yl)pyrimidin-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 275 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301782 (2-(3-chlorophenethyl)-3-methyl-6-(piperazin-1-yl)p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 96 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301783 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-phenethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 262 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301784 ((R)-2-(3-chlorophenethyl)-3-methyl-6-(2-methylpipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301785 ((R)-2-(2-chlorophenethyl)-3-methyl-6-(2-methylpipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301786 ((R)-3-methyl-2-(2-methylphenethyl)-6-(2-methylpipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301787 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-(2-(trif...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 64 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301788 (6-methyl-3-(3-phenylpropyl)-2-(piperazin-1-yl)pyri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301789 (3-(3-(benzyloxy)propyl)-6-methyl-2-(piperazin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301790 (2-(2-chlorophenethyl)-3-ethyl-6-(piperazin-1-yl)py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301791 (3-methyl-6-(piperazin-1-yl)-2-((2-(trifluoromethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301792 (2-((2-chlorophenoxy)methyl)-3-methyl-6-(piperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 73 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301793 (3-methyl-6-(piperazin-1-yl)-2-(o-tolyloxymethyl)py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 228 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301794 (3-methyl-6-(piperazin-1-yl)-2-((3-(trifluoromethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 487 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301795 (2-((3-chlorophenoxy)methyl)-3-methyl-6-(piperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 493 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301796 (3-((1-methyl-6-oxo-4-(piperazin-1-yl)-1,6-dihydrop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 319 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301797 (3-methyl-6-(piperazin-1-yl)-2-((4-(trifluoromethyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301798 (2-((4-chlorophenoxy)methyl)-3-methyl-6-(piperazin-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301799 (2-((5-fluoro-2-methylphenoxy)methyl)-3-methyl-6-(p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 46 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301800 (2-((5-chloro-2-methylphenoxy)methyl)-3-methyl-6-(p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301801 (2-((2-chloro-5-fluorophenoxy)methyl)-3-methyl-6-(p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 361 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50301802 (3-((1-ethyl-6-oxo-4-(piperazin-1-yl)-1,6-dihydropy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 112 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.50E+3 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2A receptor transfected in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50301770 ((R)-3-methyl-6-(2-methylpiperazin-1-yl)-2-((2-(tri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Agonist activity at human recombinant 5HT2B receptor transfected in CHO K1 cells assessed as calcium mobilisation by FLIPR assay | Bioorg Med Chem Lett 19: 5346-50 (2009) Article DOI: 10.1016/j.bmcl.2009.07.133 BindingDB Entry DOI: 10.7270/Q2B56JT3 | |||||||||||
More data for this Ligand-Target Pair |