Found 57 hits with Last Name = 'pearce' and Initial = 'cj' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50042034
((5Z)-7-Oxozeaenol | 5Z-7-Oxozeaenol | CHEBI:67559 ...)Show SMILES COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O |r,c:19,t:10| Show InChI InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,15,18,21-23H,5,8H2,1-2H3/b6-4+,7-3-/t11-,15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) expressed in sf9 cells assessed as 32P level incorporation into myelin basic protein incubated for 5 mins at 30 d... |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50042034
((5Z)-7-Oxozeaenol | 5Z-7-Oxozeaenol | CHEBI:67559 ...)Show SMILES COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O |r,c:19,t:10| Show InChI InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,15,18,21-23H,5,8H2,1-2H3/b6-4+,7-3-/t11-,15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50129131
(CHEBI:83275 | Hypothemycin | US10434085, Compound ...)Show SMILES [H][C@@]12C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:9| Show InChI InChI=1S/C19H22O8/c1-9-4-3-5-12(20)17(23)14(22)8-15-18(27-15)11-6-10(25-2)7-13(21)16(11)19(24)26-9/h3,5-7,9,14-15,17-18,21-23H,4,8H2,1-2H3/b5-3-/t9-,14-,15+,17+,18+/m0/s1 | PDB
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antibodypedia
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| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Patents
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129131
(CHEBI:83275 | Hypothemycin | US10434085, Compound ...)Show SMILES [H][C@@]12C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:9| Show InChI InChI=1S/C19H22O8/c1-9-4-3-5-12(20)17(23)14(22)8-15-18(27-15)11-6-10(25-2)7-13(21)16(11)19(24)26-9/h3,5-7,9,14-15,17-18,21-23H,4,8H2,1-2H3/b5-3-/t9-,14-,15+,17+,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Patents
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50196926
(CHEMBL438139 | Rocaglamide | US10085988, Compound ...)Show SMILES COc1ccc(cc1)[C@@]12Oc3cc(OC)cc(OC)c3[C@]1(O)[C@H](O)[C@@H]([C@H]2c1ccccc1)C(=O)N(C)C |r| Show InChI InChI=1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,33H,1-5H3/t23-,24-,26-,28+,29+/m1/s1 | PDB
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CHEMBL
MCE
PC cid
PC sid
PDB
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Patents
Similars
| Article
PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISA |
J Nat Prod 74: 1126-31 (2011)
Article DOI: 10.1021/np200062x
BindingDB Entry DOI: 10.7270/Q25M6621 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129130
(CHEMBL3629241)Show SMILES COC1=CC(O)C2=C(\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O)C1(F)F |r,c:17,t:2,6,8| Show InChI InChI=1S/C19H22F2O7/c1-10-5-3-7-12(22)17(25)13(23)8-4-6-11-16(18(26)28-10)14(24)9-15(27-2)19(11,20)21/h3-4,6-7,9-10,13-14,17,23-25H,5,8H2,1-2H3/b6-4+,7-3-/t10-,13-,14?,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
A5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436
(Homo sapiens (Human)) | BDBM50593519
(CHEMBL5204252)Show SMILES [H][C@]1(NC(=O)[C@@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](Cc2ccc(O)cc2)\N=C/[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CO)NC1=O)C(C)C)[C@@H](C)CC |r,c:28| | PDB
UniProtKB/SwissProt
antibodypedia
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antibodypedia
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antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00036
BindingDB Entry DOI: 10.7270/Q2J10752 |
More data for this
Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50336457
((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(=O)CCC[C@H](C)OC2=O)c1 |r| Show InChI InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,22H,3-8H2,1-2H3/t11-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISA |
J Nat Prod 74: 1126-31 (2011)
Article DOI: 10.1021/np200062x
BindingDB Entry DOI: 10.7270/Q25M6621 |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129129
(CHEMBL3629242 | US10434085, Compound 7)Show SMILES COc1cc(O)c2c(\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O)c1Br |r,c:17,t:8| Show InChI InChI=1S/C19H21BrO7/c1-10-5-3-7-12(21)18(24)13(22)8-4-6-11-16(19(25)27-10)14(23)9-15(26-2)17(11)20/h3-4,6-7,9-10,13,18,22-24H,5,8H2,1-2H3/b6-4+,7-3-/t10-,13-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129128
(CHEMBL3629243 | US10434085, Compound 10)Show SMILES [H][C@]12C\C=C\c3cc(OC)cc(O)c3C(=O)O[C@@H](C)C\C=C/C(=O)[C@@]1([H])OC(C)(C)O2 |r,c:21,t:3| Show InChI InChI=1S/C22H26O7/c1-13-7-5-9-16(23)20-18(28-22(2,3)29-20)10-6-8-14-11-15(26-4)12-17(24)19(14)21(25)27-13/h5-6,8-9,11-13,18,20,24H,7,10H2,1-4H3/b8-6+,9-5-/t13-,18-,20?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594358
(CHEMBL5204235)Show SMILES [H][C@@]12C[C@H](OC(=O)\C=C/C(O)=O)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:16| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594353
(CHEMBL5174288)Show SMILES [H][C@@]12C[C@H](OC(C)=O)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:12| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594354
(CHEMBL5186931)Show SMILES [H][C@@]12C[C@H](O)[C@H](OC(C)=O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:12| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594367
(CHEMBL5207996)Show SMILES [H][C@@]12C[C@H](OC(=O)OCC)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:14| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594360
(CHEMBL5173905)Show SMILES [H][C@@]12C[C@H](OC(=O)OC)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:13| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594364
(CHEMBL5185893)Show SMILES [H][C@@]12C[C@H](OC(=O)OCC=C)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:15| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594356
(CHEMBL5179846)Show SMILES [H][C@@]12C[C@H](OC(=O)CCC(O)=O)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:16| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50347543
(CHEMBL1801948)Show SMILES C[C@H]1CCCC(=O)C(=O)C(=O)CCCc2cc(O)cc(O)c2C(=O)O1 Show InChI InChI=1S/C18H20O7/c1-10-4-2-6-13(20)17(23)14(21)7-3-5-11-8-12(19)9-15(22)16(11)18(24)25-10/h8-10,19,22H,2-7H2,1H3/t10-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISA |
J Nat Prod 74: 1126-31 (2011)
Article DOI: 10.1021/np200062x
BindingDB Entry DOI: 10.7270/Q25M6621 |
More data for this
Ligand-Target Pair | |
Histone-lysine N-methyltransferase 2A
(Homo sapiens (Human)) | BDBM50530867
(CHEMBL4472654)Show SMILES [H][C@]12Nc3ccccc3[C@]1([C@H](O)[C@]13SS[C@](C)(N(C)C1=O)C(=O)N23)[C@]12[C@H](O)[C@]34SS[C@](C)(N(C)C3=O)C(=O)N4[C@@]1([H])Nc1ccccc21 |r| Show InChI InChI=1S/C30H28N6O6S4/c1-25-21(39)35-19-27(13-9-5-7-11-15(13)31-19,17(37)29(35,45-43-25)23(41)33(25)3)28-14-10-6-8-12-16(14)32-20(28)36-22(40)26(2)34(4)24(42)30(36,18(28)38)46-44-26/h5-12,17-20,31-32,37-38H,1-4H3/t17-,18-,19+,20+,25-,26-,27+,28+,29-,30-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MLL1 using [3H]S-adenosyl-methionine as substrate |
J Nat Prod 82: 3104-3110 (2019)
Article DOI: 10.1021/acs.jnatprod.9b00711
BindingDB Entry DOI: 10.7270/Q2C53QB2 |
More data for this
Ligand-Target Pair | |
Histone-lysine N-methyltransferase 2A
(Homo sapiens (Human)) | BDBM50530867
(CHEMBL4472654)Show SMILES [H][C@]12Nc3ccccc3[C@]1([C@H](O)[C@]13SS[C@](C)(N(C)C1=O)C(=O)N23)[C@]12[C@H](O)[C@]34SS[C@](C)(N(C)C3=O)C(=O)N4[C@@]1([H])Nc1ccccc21 |r| Show InChI InChI=1S/C30H28N6O6S4/c1-25-21(39)35-19-27(13-9-5-7-11-15(13)31-19,17(37)29(35,45-43-25)23(41)33(25)3)28-14-10-6-8-12-16(14)32-20(28)36-22(40)26(2)34(4)24(42)30(36,18(28)38)46-44-26/h5-12,17-20,31-32,37-38H,1-4H3/t17-,18-,19+,20+,25-,26-,27+,28+,29-,30-/m0/s1 | PDB
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| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MLL1 using [3H]S-adenosyl-methionine as substrate |
J Nat Prod 82: 3104-3110 (2019)
Article DOI: 10.1021/acs.jnatprod.9b00711
BindingDB Entry DOI: 10.7270/Q2C53QB2 |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594365
(CHEMBL5186989)Show SMILES [H][C@@]12C[C@H](O)[C@H](OC(=O)OCC=C)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:15| | PDB
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| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594361
(CHEMBL5174742)Show SMILES [H][C@@]12C[C@H](O)[C@H](OC(=O)OC)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:13| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129127
(CHEMBL3629244)Show SMILES [H][C@@]12C[C@H](O)[C@H](O)C(=O)\C=C\C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,t:9| Show InChI InChI=1S/C19H22O8/c1-9-4-3-5-12(20)17(23)14(22)8-15-18(27-15)11-6-10(25-2)7-13(21)16(11)19(24)26-9/h3,5-7,9,14-15,17-18,21-23H,4,8H2,1-2H3/b5-3+/t9-,14-,15+,17+,18+/m0/s1 | PDB
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| n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594377
(CHEMBL5183713)Show SMILES [H][C@@]12C[C@]3([H])OC(C)(C)O[C@]3([H])C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:15| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594378
(CHEMBL5174017)Show SMILES COc1cc(O)c2c(Cc3ccc(o3)C(=O)\C=C/C[C@H](C)OC2=O)c1 |r,c:17| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594376
(CHEMBL5207341)Show SMILES [H][C@@]12C[C@H](OS(=O)(=O)c3ccc(C)cc3)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:20| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594375
(CHEMBL5181612)Show SMILES [H][C@@]12C[C@H](OS(C)(=O)=O)[C@H](OS(C)(=O)=O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:17| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594374
(CHEMBL5203686)Show SMILES [H][C@@]12C[C@H](OC(=O)OCc3ccccc3)[C@H](OC(=O)OCc3ccccc3)C(=O)\C=C/C[C@H](C)OC(=O)c3c(OC(=O)OCc4ccccc4)cc(OC)cc3[C@@]1([H])O2 |r,c:31| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594373
(CHEMBL5198327)Show SMILES [H][C@@]12C[C@H](OC(=O)OCc3ccccc3)[C@H](OC(=O)OCc3ccccc3)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:31| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594372
(CHEMBL5188253)Show SMILES [H][C@@]12C[C@H](O)[C@H](OC(=O)OCc3ccccc3)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:20| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594371
(CHEMBL5190572)Show SMILES [H][C@@]12C[C@H](OC(=O)OCc3ccccc3)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:20| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594370
(CHEMBL5208768)Show SMILES [H][C@@]12C[C@H](OC(=O)OCC)[C@H](OC(=O)OCC)C(=O)\C=C/C[C@H](C)OC(=O)c3c(OC(=O)OCC)cc(OC)cc3[C@@]1([H])O2 |r,c:19| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594369
(CHEMBL5173639)Show SMILES [H][C@@]12C[C@H](OC(=O)OCC)[C@H](OC(=O)OCC)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:19| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594366
(CHEMBL5188775)Show SMILES [H][C@@]12C[C@H](OC(=O)OCC=C)[C@H](OC(=O)OCC=C)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:21| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594363
(CHEMBL5196408)Show SMILES [H][C@@]12C[C@H](OC(=O)OC)[C@H](OC(=O)OC)C(=O)\C=C/C[C@H](C)OC(=O)c3c(OC(=O)OC)cc(OC)cc3[C@@]1([H])O2 |r,c:17| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594362
(CHEMBL5187912)Show SMILES [H][C@@]12C[C@H](OC(=O)OC)[C@H](OC(=O)OC)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:17| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594357
(CHEMBL5203951)Show SMILES [H][C@@]12C[C@H](OC(=O)CCC(O)=O)[C@H](OC(=O)CCC(O)=O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:23| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594355
(CHEMBL5196981)Show SMILES [H][C@@]12C[C@H](OC(C)=O)[C@H](OC(C)=O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:15| | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594359
(CHEMBL5185951)Show SMILES [H][C@@]12C[C@H](OC(=O)\C=C/C(O)=O)[C@H](OC(=O)\C=C/C(O)=O)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:23| | PDB
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| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129126
((5E)-7-Oxozeaenol | CHEBI:67558 | CHEMBL1801950 | ...)Show SMILES COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)\C=C\C[C@H](C)OC2=O |r,t:10,19| Show InChI InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,15,18,21-23H,5,8H2,1-2H3/b6-4+,7-3+/t11-,15-,18+/m0/s1 | PDB
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Reactome pathway
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| PDB
Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Nuclear receptor subfamily 2 group C member 2/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
(Homo sapiens (Human)) | BDBM50594368
(CHEMBL5186228)Show SMILES [H][C@@]12C[C@H](O)[C@H](OC(=O)OCC)C(=O)\C=C/C[C@H](C)OC(=O)c3c(O)cc(OC)cc3[C@@]1([H])O2 |r,c:14| | PDB
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| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jnatprod.2c00434
BindingDB Entry DOI: 10.7270/Q21N854C |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129125
(CHEMBL3629245 | US10434085, Compound 6)Show SMILES COc1cc2\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC(=O)c2c(O)c1Br |r,c:14,t:5| Show InChI InChI=1S/C19H21BrO7/c1-10-5-3-7-12(21)17(23)13(22)8-4-6-11-9-14(26-2)16(20)18(24)15(11)19(25)27-10/h3-4,6-7,9-10,13,17,22-24H,5,8H2,1-2H3/b6-4+,7-3-/t10-,13-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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UniChem
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PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50347546
(CHEMBL1801951 | US10434085, Compound LL-Z164-1)Show SMILES COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)C(=O)CCC[C@H](C)OC2=O |r,t:10| Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h4,6,9-11,15,18,21-23H,3,5,7-8H2,1-2H3/b6-4+/t11-,15-,18+/m0/s1 | PDB
MMDB
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UniChem
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| Article
PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM14361
((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)Show InChI InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) | PDB
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| PDB
Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B2 |
J Nat Prod 76: 382-7 (2013)
Article DOI: 10.1021/np300749w
BindingDB Entry DOI: 10.7270/Q2TX3GQQ |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129124
(CHEMBL3629246 | US10434085, Compound 8)Show SMILES COc1c(Br)c(O)c2c(\C=C\C[C@H](O)[C@H](O)C(=O)\C=C/C[C@H](C)OC2=O)c1Br |r,c:18,t:9| Show InChI InChI=1S/C19H20Br2O7/c1-9-5-3-7-11(22)16(24)12(23)8-4-6-10-13(19(26)28-9)17(25)15(21)18(27-2)14(10)20/h3-4,6-7,9,12,16,23-25H,5,8H2,1-2H3/b6-4+,7-3-/t9-,12-,16+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50347544
(US10434085, Compound zeaenol | ZEAENOL)Show SMILES COc1cc(O)c2c(c1)\C=C\C[C@H](O)[C@H](O)[C@@H](O)\C=C\C[C@H](C)OC2=O |r,t:10,19| Show InChI InChI=1S/C19H24O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h3-4,6-7,9-11,14-15,18,20-23H,5,8H2,1-2H3/b6-4+,7-3+/t11-,14-,15-,18+/m0/s1 | PDB
MMDB
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PC sid
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PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50336457
((3S,5Z,8S,9R,11E)-8,9,16-trihydroxy-14-methoxy-3-m...)Show SMILES COc1cc(O)c2c(CCCC(=O)C(=O)C(=O)CCC[C@H](C)OC2=O)c1 |r| Show InChI InChI=1S/C19H22O7/c1-11-5-3-7-14(20)18(23)15(21)8-4-6-12-9-13(25-2)10-16(22)17(12)19(24)26-11/h9-11,22H,3-8H2,1-2H3/t11-/m0/s1 | PDB
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PubMed
| n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISA |
J Nat Prod 74: 1126-31 (2011)
Article DOI: 10.1021/np200062x
BindingDB Entry DOI: 10.7270/Q25M6621 |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
(Homo sapiens (Human)) | BDBM50428912
(Betulinan C | CHEMBL2331809)Show SMILES COC1=C(C(=O)C=C(C1=O)c1ccccc1)c1ccccc1 |c:6,t:2| Show InChI InChI=1S/C19H14O3/c1-22-19-17(14-10-6-3-7-11-14)16(20)12-15(18(19)21)13-8-4-2-5-9-13/h2-12H,1H3 | PDB
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PubMed
| n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of human PDE4B2 |
J Nat Prod 76: 382-7 (2013)
Article DOI: 10.1021/np300749w
BindingDB Entry DOI: 10.7270/Q2TX3GQQ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129085
(CHEMBL3334712)Show SMILES COc1cc(O)cc2CC(=O)\C=C\CCCCC[C@H](C)OC(=O)c12 |r,t:11| Show InChI InChI=1S/C19H24O5/c1-13-8-6-4-3-5-7-9-15(20)10-14-11-16(21)12-17(23-2)18(14)19(22)24-13/h7,9,11-13,21H,3-6,8,10H2,1-2H3/b9-7+/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
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B.MOAD
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 7
(Homo sapiens (Human)) | BDBM50129083
(CHEMBL3628303)Show SMILES [H][C@]12C\C=C\C3=CC(OC)=CC(O)C3C(=O)O[C@@H](C)CC(CC(=O)[C@H]1O)O2 |r,c:9,t:3,5| Show InChI InChI=1S/C19H24O7/c1-10-6-13-9-15(21)18(22)16(26-13)5-3-4-11-7-12(24-2)8-14(20)17(11)19(23)25-10/h3-4,7-8,10,13-14,16-18,20,22H,5-6,9H2,1-2H3/b4-3+/t10-,13?,14?,16-,17?,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina at Greensboro
Curated by ChEMBL
| Assay Description
Inhibition of TAK1 (unknown origin) |
Bioorg Med Chem 23: 6993-9 (2015)
Article DOI: 10.1016/j.bmc.2015.09.037
BindingDB Entry DOI: 10.7270/Q25D8TNS |
More data for this
Ligand-Target Pair | |
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