Compile Data Set for Download or QSAR

Found 171 hits with Last Name = 'riedinger' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111568 (US8618158, NCL-00016149) Show SMILES OC(=O)CCC(=O)OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 |w:12.11| Show InChI InChI=1S/C30H26Cl2N2O8/c31-21-8-6-20(7-9-21)30(42-18-29(14-15-29)17-41-26(37)13-12-25(35)36)27-23(2-1-3-24(27)32)28(38)33(30)16-19-4-10-22(11-5-19)34(39)40/h1-11H,12-18H2,(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111547 (US8618158, NCL-00013774 | US8618158, NCL-00013775 ...) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H22Cl2N2O5/c27-19-8-6-18(7-9-19)26(35-16-25(15-31)12-13-25)23-21(2-1-3-22(23)28)24(32)29(26)14-17-4-10-20(11-5-17)30(33)34/h1-11,31H,12-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50229787 ((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...) Show SMILES COc1ccc(C2=N[C@H]([C@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1 |t:6| Show InChI InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)/t27-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111569 (US8618158, NCL-00016659) Show SMILES OC(=O)CCC(=O)OCC1(COC2(N(Cc3ccc(cc3)C#N)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 |w:12.11| Show InChI InChI=1S/C31H26Cl2N2O6/c32-23-10-8-22(9-11-23)31(41-19-30(14-15-30)18-40-27(38)13-12-26(36)37)28-24(2-1-3-25(28)33)29(39)35(31)17-21-6-4-20(16-34)5-7-21/h1-11H,12-15,17-19H2,(H,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111570 (US8618158, NCL-00016653) Show SMILES OC(=O)CCC(=O)OCC1(COC2(N(Cc3ccc(Br)cc3)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 |w:12.11| Show InChI InChI=1S/C30H26BrCl2NO6/c31-21-8-4-19(5-9-21)16-34-28(38)23-2-1-3-24(33)27(23)30(34,20-6-10-22(32)11-7-20)40-18-29(14-15-29)17-39-26(37)13-12-25(35)36/h1-11H,12-18H2,(H,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111547 (US8618158, NCL-00013774 | US8618158, NCL-00013775 ...) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H22Cl2N2O5/c27-19-8-6-18(7-9-19)26(35-16-25(15-31)12-13-25)23-21(2-1-3-22(23)28)24(32)29(26)14-17-4-10-20(11-5-17)30(33)34/h1-11,31H,12-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111532 (US8618158, NU8399) Show SMILES CC(C)(C)c1ccc2c(c1)C(=O)N(Cc1ccc(cc1)[N+]([O-])=O)C2(OCC1(CO)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C30H31ClN2O5/c1-28(2,3)22-8-13-26-25(16-22)27(35)32(17-20-4-11-24(12-5-20)33(36)37)30(26,21-6-9-23(31)10-7-21)38-19-29(18-34)14-15-29/h4-13,16,34H,14-15,17-19H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111540 (US8618158, NCL-00010493) Show SMILES OCC1(COC2(N(Cc3ccc(Br)cc3)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H22BrCl2NO3/c27-19-8-4-17(5-9-19)14-30-24(32)21-2-1-3-22(29)23(21)26(30,18-6-10-20(28)11-7-18)33-16-25(15-31)12-13-25/h1-11,31H,12-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339398 ((+)-R-3-(4-Chlorophenyl)-3-(1-hydroxymethylcyclopr...) Show SMILES OCC1(CO[C@]2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |r| Show InChI InChI=1S/C26H23ClN2O5/c27-20-9-7-19(8-10-20)26(34-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)28(26)15-18-5-11-21(12-6-18)29(32)33/h1-12,30H,13-17H2/t26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111539 (US8618158, NCL-00010492) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)C#N)C(=O)c3cccc(Cl)c23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C27H22Cl2N2O3/c28-21-10-8-20(9-11-21)27(34-17-26(16-32)12-13-26)24-22(2-1-3-23(24)29)25(33)31(27)15-19-6-4-18(14-30)5-7-19/h1-11,32H,12-13,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339369 ((+/-)-3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cycl...) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H23ClN2O5/c27-20-9-7-19(8-10-20)26(34-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)28(26)15-18-5-11-21(12-6-18)29(32)33/h1-12,30H,13-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111546 (US8618158, NU8405) Show SMILES Cc1cccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(OCC3(CO)CC3)(c12)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClN2O5/c1-18-3-2-4-23-24(18)27(20-7-9-21(28)10-8-20,35-17-26(16-31)13-14-26)29(25(23)32)15-19-5-11-22(12-6-19)30(33)34/h2-12,31H,13-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111542 (US8618158, NCL-00010495) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccc(F)cc23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H22ClFN2O5/c27-19-5-3-18(4-6-19)26(35-16-25(15-31)11-12-25)23-13-20(28)7-10-22(23)24(32)29(26)14-17-1-8-21(9-2-17)30(33)34/h1-10,13,31H,11-12,14-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	295	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111513 (US8618158, NU8354) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |w:5.4| Show InChI InChI=1S/C26H23ClN2O5/c27-20-9-7-19(8-10-20)26(34-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)28(26)15-18-5-11-21(12-6-18)29(32)33/h1-12,30H,13-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111518 (US8618158, NU8361) Show SMILES O[C@H]1CC[C@H](OC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1 |r,w:6.5,c:37| Show InChI InChI=1S/C27H23ClN2O5/c28-20-9-7-19(8-10-20)27(35-23-15-13-22(31)14-16-23)25-4-2-1-3-24(25)26(32)29(27)17-18-5-11-21(12-6-18)30(33)34/h1-13,15,22-23,31H,14,16-17H2/t22-,23-,27?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	306	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339371 ((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxycyclohe...) Show SMILES O[C@H]1CC[C@H](OC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1 |r,c:37| Show InChI InChI=1S/C27H23ClN2O5/c28-20-9-7-19(8-10-20)27(35-23-15-13-22(31)14-16-23)25-4-2-1-3-24(25)26(32)29(27)17-18-5-11-21(12-6-18)30(33)34/h1-13,15,22-23,31H,14,16-17H2/t22-,23-,27?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339355 ((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybutoxy)-2-(4-...) Show SMILES OCCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H23ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-2,5-14,29H,3-4,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111524 (US8618158, NU8391) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Br)cc2)CC1 |w:5.4| Show InChI InChI=1S/C26H23BrN2O5/c27-20-9-7-19(8-10-20)26(34-17-25(16-30)13-14-25)23-4-2-1-3-22(23)24(31)28(26)15-18-5-11-21(12-6-18)29(32)33/h1-12,30H,13-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111511 (US8618158, NU8352) Show SMILES O[C@H]1CCC[C@H](CCC1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r,w:10.10| Show InChI InChI=1S/C29H29ClN2O5/c30-22-15-13-21(14-16-22)29(37-25-7-3-5-24(33)6-4-8-25)27-10-2-1-9-26(27)28(34)31(29)19-20-11-17-23(18-12-20)32(35)36/h1-2,9-18,24-25,33H,3-8,19H2/t24-,25+,29?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339365 ((+/-)-trans-3-(4-Chlorophenyl)-3-(5-hydroxycyclooc...) Show SMILES O[C@H]1CCC[C@@H](CCC1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C29H29ClN2O5/c30-22-15-13-21(14-16-22)29(37-25-7-3-5-24(33)6-4-8-25)27-10-2-1-9-26(27)28(34)31(29)19-20-11-17-23(18-12-20)32(35)36/h1-2,9-18,24-25,33H,3-8,19H2/t24-,25-,29?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111517 (US8618158, NU8360) Show SMILES OC1CC[C@@H](CC1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r,w:8.8,1.0,wU:4.7,(-4.44,7.19,;-4.04,5.7,;-5.13,4.61,;-4.73,3.12,;-3.25,2.72,;-2.16,3.81,;-2.56,5.3,;-2.85,1.24,;-2.08,-.1,;-1.17,-1.34,;.37,-1.34,;1.46,-2.43,;1.06,-3.92,;2.15,-5.01,;3.63,-4.61,;4.03,-3.12,;2.94,-2.03,;4.72,-5.7,;4.32,-7.19,;6.21,-5.3,;-2.08,-2.59,;-1.31,-3.92,;-3.54,-2.11,;-4.88,-2.88,;-6.21,-2.11,;-6.21,-.57,;-4.88,.2,;-3.54,-.57,;-.99,.99,;.5,.59,;1.59,1.68,;1.19,3.17,;2.28,4.26,;-.3,3.57,;-1.39,2.48,)| Show InChI InChI=1S/C27H25ClN2O5/c28-20-9-7-19(8-10-20)27(35-23-15-13-22(31)14-16-23)25-4-2-1-3-24(25)26(32)29(27)17-18-5-11-21(12-6-18)30(33)34/h1-12,22-23,31H,13-17H2/t22?,23-,27?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	388	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339370 ((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxycyclohe...) Show SMILES O[C@H]1CC[C@@H](CC1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r,wU:4.7,wD:1.0,(-9.71,-36.66,;-8.4,-37.46,;-8.44,-39,;-7.12,-39.8,;-5.79,-39.06,;-5.74,-37.53,;-7.05,-36.73,;-4.48,-39.85,;-4.08,-41.35,;-3.16,-42.6,;-1.62,-42.6,;-.85,-43.93,;-1.62,-45.27,;-.86,-46.6,;.69,-46.6,;1.46,-45.26,;.68,-43.93,;1.47,-47.94,;.7,-49.28,;3.01,-47.94,;-4.08,-43.86,;-3.6,-45.32,;-5.55,-43.38,;-6.88,-44.15,;-8.22,-43.38,;-8.22,-41.83,;-6.89,-41.06,;-5.55,-41.82,;-2.76,-40.55,;-1.41,-41.31,;-.09,-40.52,;-.11,-38.97,;1.21,-38.18,;-1.47,-38.23,;-2.79,-39.02,)| Show InChI InChI=1S/C27H25ClN2O5/c28-20-9-7-19(8-10-20)27(35-23-15-13-22(31)14-16-23)25-4-2-1-3-24(25)26(32)29(27)17-18-5-11-21(12-6-18)30(33)34/h1-12,22-23,31H,13-17H2/t22-,23-,27?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111512 (US8618158, NU8353) Show SMILES CC(C)(CO)COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:7.6| Show InChI InChI=1S/C26H25ClN2O5/c1-25(2,16-30)17-34-26(19-9-11-20(27)12-10-19)23-6-4-3-5-22(23)24(31)28(26)15-18-7-13-21(14-8-18)29(32)33/h3-14,30H,15-17H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	395	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339353 ((+/-)-(Z)-3-(4-Chlorophenyl)-3-(4-hydroxybut-2-eny...) Show SMILES OC\C=C/COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H21ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-14,29H,15-17H2/b4-3-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339437 ((+/-)-3-(4-chlorophenyl)-3-((cis)-3-hydroxycyclope...) Show SMILES O[C@@H]1CC[C@@H](C1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H23ClN2O5/c27-19-9-7-18(8-10-19)26(34-22-14-13-21(30)15-22)24-4-2-1-3-23(24)25(31)28(26)16-17-5-11-20(12-6-17)29(32)33/h1-12,21-22,30H,13-16H2/t21-,22+,26?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339368 ((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxy-2,2-dimethyl...) Show SMILES CC(C)(CO)COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H25ClN2O5/c1-25(2,16-30)17-34-26(19-9-11-20(27)12-10-19)23-6-4-3-5-22(23)24(31)28(26)15-18-7-13-21(14-8-18)29(32)33/h3-14,30H,15-17H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111509 (US8618158, NU8350) Show SMILES OC\C=C/COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5| Show InChI InChI=1S/C25H21ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-14,29H,15-17H2/b4-3-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	402	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111510 (US8618158, NU8351) Show SMILES OCC=CCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5,2.1| Show InChI InChI=1S/C25H21ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-14,29H,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339354 ((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxypropoxy)-2-(4...) Show SMILES OCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H21ClN2O5/c25-19-10-8-18(9-11-19)24(32-15-3-14-28)22-5-2-1-4-21(22)23(29)26(24)16-17-6-12-20(13-7-17)27(30)31/h1-2,4-13,28H,3,14-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111545 (US8618158, NU8401) Show SMILES Cc1ccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(OCC3(CO)CC3)(c2c1)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H25ClN2O5/c1-18-2-11-23-24(14-18)27(20-5-7-21(28)8-6-20,35-17-26(16-31)12-13-26)29(25(23)32)15-19-3-9-22(10-4-19)30(33)34/h2-11,14,31H,12-13,15-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	492	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111554 (US8618158, NU8398) Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2cccc(Cl)c12)c1ccc(Cl)cc1 |w:1.0| Show InChI InChI=1S/C21H14Cl2N2O4/c22-15-8-6-14(7-9-15)21(27)19-17(2-1-3-18(19)23)20(26)24(21)12-13-4-10-16(11-5-13)25(28)29/h1-11,27H,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111531 (US8618158, NU8398) Show SMILES OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2cccc(Cl)c12)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H14Cl2N2O4/c22-15-8-6-14(7-9-15)21(27)19-17(2-1-3-18(19)23)20(26)24(21)12-13-4-10-16(11-5-13)25(28)29/h1-11,27H,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111516 (US8618158, NU8359) Show SMILES OC[C@H]1CCCC[C@H]1COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r,w:10.10| Show InChI InChI=1S/C29H29ClN2O5/c30-24-13-11-23(12-14-24)29(37-19-22-6-2-1-5-21(22)18-33)27-8-4-3-7-26(27)28(34)31(29)17-20-9-15-25(16-10-20)32(35)36/h3-4,7-16,21-22,33H,1-2,5-6,17-19H2/t21-,22+,29?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	569	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339361 ((+/-)-3-(4-Bromophenyl)-3-(4-hydroxybutoxy)-2-(4-n...) Show SMILES OCCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Br)cc1 Show InChI InChI=1S/C25H23BrN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-2,5-14,29H,3-4,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339367 ((+/-)-cis-3-(4-Chlorophenyl)-3-(2-hydroxymethylcyc...) Show SMILES OC[C@H]1CCCC[C@H]1COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C29H29ClN2O5/c30-24-13-11-23(12-14-24)29(37-19-22-6-2-1-5-21(22)18-33)27-8-4-3-7-26(27)28(34)31(29)17-20-9-15-25(16-10-20)32(35)36/h3-4,7-16,21-22,33H,1-2,5-6,17-19H2/t21-,22+,29?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111523 (US8618158, NU8390) Show SMILES OCCCCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Br)cc1 |w:6.5| Show InChI InChI=1S/C25H23BrN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-2,5-14,29H,3-4,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339363 ((+/-)-trans-3-(4-Chlorophenyl)-3-(4-hydroxymethylc...) Show SMILES OC[C@H]1CC[C@H](COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |r,wU:5.5,wD:2.1,(-7.05,-6.08,;-8.14,-7.17,;-7.74,-8.66,;-8.83,-9.76,;-8.42,-11.24,;-6.94,-11.63,;-6.54,-13.11,;-5.05,-13.51,;-4.65,-15,;-3.74,-16.26,;-2.2,-16.26,;-1.43,-17.59,;-2.2,-18.92,;-1.43,-20.25,;.11,-20.25,;.88,-18.91,;.11,-17.58,;.89,-21.59,;.12,-22.93,;2.43,-21.59,;-4.65,-17.51,;-4.17,-18.98,;-6.12,-17.03,;-7.45,-17.8,;-8.79,-17.03,;-8.78,-15.49,;-7.46,-14.72,;-6.12,-15.48,;-3.33,-14.21,;-1.98,-14.96,;-.66,-14.17,;-.69,-12.63,;.63,-11.84,;-2.04,-11.88,;-3.36,-12.68,;-5.85,-10.54,;-6.25,-9.06,)| Show InChI InChI=1S/C29H29ClN2O5/c30-24-13-11-23(12-14-24)29(37-19-22-7-5-21(18-33)6-8-22)27-4-2-1-3-26(27)28(34)31(29)17-20-9-15-25(16-10-20)32(35)36/h1-4,9-16,21-22,33H,5-8,17-19H2/t21-,22-,29?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111515 (US8618158, NU8358) Show SMILES OC[C@H]1CC[C@H](COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)CC1 |r,w:8.7,wU:5.5,wD:2.1,(-5.52,8.06,;-4.18,7.29,;-4.18,5.75,;-5.52,4.98,;-5.52,3.44,;-4.18,2.67,;-4.18,1.13,;-2.85,.36,;-2.08,-.97,;-1.17,-2.22,;.37,-2.22,;1.46,-3.31,;1.06,-4.79,;2.15,-5.88,;3.63,-5.49,;4.03,-4,;2.94,-2.91,;4.72,-6.57,;4.32,-8.06,;6.21,-6.18,;-2.08,-3.46,;-1.31,-4.8,;-3.54,-2.99,;-4.88,-3.76,;-6.21,-2.99,;-6.21,-1.45,;-4.88,-.68,;-3.54,-1.45,;-.99,.12,;.5,-.28,;1.59,.81,;1.19,2.29,;2.28,3.38,;-.3,2.69,;-1.39,1.6,;-2.85,3.44,;-2.85,4.98,)| Show InChI InChI=1S/C29H29ClN2O5/c30-24-13-11-23(12-14-24)29(37-19-22-7-5-21(18-33)6-8-22)27-4-2-1-3-26(27)28(34)31(29)17-20-9-15-25(16-10-20)32(35)36/h1-4,9-16,21-22,33H,5-8,17-19H2/t21-,22-,29?	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	582	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111514 (US8618158, NU8357) Show SMILES OCC#CCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5| Show InChI InChI=1S/C25H19ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-2,5-14,29H,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	656	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339366 ((+/-)-3-(4-Chlorophenyl)-3-(4-hydroxybut-2-ynyloxy...) Show SMILES OCC#CCOC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H19ClN2O5/c26-20-11-9-19(10-12-20)25(33-16-4-3-15-29)23-6-2-1-5-22(23)24(30)27(25)17-18-7-13-21(14-8-18)28(31)32/h1-2,5-14,29H,15-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111573 (US8618158, NCL-00016895) Show SMILES OCC(=C)COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 |w:6.5| Show InChI InChI=1S/C25H21ClN2O5/c1-17(15-29)16-33-25(19-8-10-20(26)11-9-19)23-5-3-2-4-22(23)24(30)27(25)14-18-6-12-21(13-7-18)28(31)32/h2-13,29H,1,14-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339436 ((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxycyclopentoxy)...) Show SMILES OC1CCC(C1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H23ClN2O5/c27-19-9-7-18(8-10-19)26(34-22-14-13-21(30)15-22)24-4-2-1-3-23(24)25(31)28(26)16-17-5-11-20(12-6-17)29(32)33/h1-12,21-22,30H,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339364 ((+/-)-3-(4-Chlorophenyl)-3-(3-hydroxymethylbenzylo...) Show SMILES OCc1cccc(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C29H23ClN2O5/c30-24-12-10-23(11-13-24)29(37-19-22-5-3-4-21(16-22)18-33)27-7-2-1-6-26(27)28(34)31(29)17-20-8-14-25(15-9-20)32(35)36/h1-16,33H,17-19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111521 (US8618158, NU8367) Show SMILES OCc1cccc(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3ccccc23)c2ccc(Cl)cc2)c1 |w:9.8| Show InChI InChI=1S/C29H23ClN2O5/c30-24-12-10-23(11-13-24)29(37-19-22-5-3-4-21(16-22)18-33)27-7-2-1-6-26(27)28(34)31(29)17-20-8-14-25(15-9-20)32(35)36/h1-16,33H,17-19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	732	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111544 (US8618158, NU8400) Show SMILES CC(C)(C)c1ccc2C(=O)N(Cc3ccc(cc3)[N+]([O-])=O)C(OCC3(CO)CC3)(c2c1)c1ccc(Cl)cc1 Show InChI InChI=1S/C30H31ClN2O5/c1-28(2,3)22-8-13-25-26(16-22)30(21-6-9-23(31)10-7-21,38-19-29(18-34)14-15-29)32(27(25)35)17-20-4-11-24(12-5-20)33(36)37/h4-13,16,34H,14-15,17-19H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	733	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111530 (US8618158, NU8397) Show SMILES CC(C)(C)c1ccc2c(c1)C(=O)N(Cc1ccc(cc1)[N+]([O-])=O)C2(O)c1ccc(Cl)cc1 Show InChI InChI=1S/C25H23ClN2O4/c1-24(2,3)18-8-13-22-21(14-18)23(29)27(15-16-4-11-20(12-5-16)28(31)32)25(22,30)17-6-9-19(26)10-7-17/h4-14,30H,15H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	837	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111538 (US8618158, NCL-00010490) Show SMILES OC1(N(Cc2ccc(Br)cc2)C(=O)c2cccc(Cl)c12)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H14BrCl2NO2/c22-15-8-4-13(5-9-15)12-25-20(26)17-2-1-3-18(24)19(17)21(25,27)14-6-10-16(23)11-7-14/h1-11,27H,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	847	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111543 (US8618158, NCL-00010496) Show SMILES OCC1(COC2(N(Cc3ccc(cc3)[N+]([O-])=O)C(=O)c3cc(F)ccc23)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H22ClFN2O5/c27-19-5-3-18(4-6-19)26(35-16-25(15-31)11-12-25)23-10-7-20(28)13-22(23)24(32)29(26)14-17-1-8-21(9-2-17)30(33)34/h1-10,13,31H,11-12,14-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	852	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM111519 (US8618158, NU8365) Show SMILES C[C@H](N1C(=O)c2ccccc2C1(OCCCCO)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r,w:11.13| Show InChI InChI=1S/C26H25Cl2NO3/c1-18(19-8-12-21(27)13-9-19)29-25(31)23-6-2-3-7-24(23)26(29,32-17-5-4-16-30)20-10-14-22(28)15-11-20/h2-3,6-15,18,30H,4-5,16-17H2,1H3/t18-,26?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	869	n/a	n/a	n/a	n/a	n/a	25
Cancer Research Technology Limited US Patent					Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...				US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM50339357 ((+/-)-(S)-3-(4-Chlorophenyl)-2-[1-(4-chlorophenyl)...) Show SMILES C[C@H](N1C(=O)c2ccccc2C1(OCCCCO)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C26H25Cl2NO3/c1-18(19-8-12-21(27)13-9-19)29-25(31)23-6-2-3-7-24(23)26(29,32-17-5-4-16-30)20-10-14-22(28)15-11-20/h2-3,6-15,18,30H,4-5,16-17H2,1H3/t18-,26?/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of Mdm2 -p53 protein interaction by ELISA				J Med Chem 54: 1233-43 (2011) Article DOI: 10.1021/jm1011929 BindingDB Entry DOI: 10.7270/Q29K4BHN
					More data for this Ligand-Target Pair

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