Compile Data Set for Download or QSAR

Found 15 hits with Last Name = 'sarmiento' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179001 (CHEMBL204761 | N2,N4-bis(3,4-difluorophenyl)-6-(4-...) Show SMILES CC(C)CN1CCN(CC1)c1nc(Nc2ccc(F)c(F)c2)nc(Nc2ccc(F)c(F)c2)n1 Show InChI InChI=1S/C23H25F4N7/c1-14(2)13-33-7-9-34(10-8-33)23-31-21(28-15-3-5-17(24)19(26)11-15)30-22(32-23)29-16-4-6-18(25)20(27)12-16/h3-6,11-12,14H,7-10,13H2,1-2H3,(H2,28,29,30,31,32)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179004 (CHEMBL203999 | N2,N4-bis(3,4-difluorophenyl)-6-(4-...) Show SMILES Fc1ccc(Nc2nc(Nc3ccc(F)c(F)c3)nc(n2)N2CCN(CCOc3ccccc3)CC2)cc1F Show InChI InChI=1S/C27H25F4N7O/c28-21-8-6-18(16-23(21)30)32-25-34-26(33-19-7-9-22(29)24(31)17-19)36-27(35-25)38-12-10-37(11-13-38)14-15-39-20-4-2-1-3-5-20/h1-9,16-17H,10-15H2,(H2,32,33,34,35,36)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179000 (CHEMBL205726 | N2-(4-chlorophenyl)-N4-(2-morpholin...) Show SMILES [O-][N+](=O)c1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc3ccc(Cl)cc3)n2)cc1 Show InChI InChI=1S/C21H23ClN8O3/c22-15-1-3-16(4-2-15)24-20-26-19(23-9-10-29-11-13-33-14-12-29)27-21(28-20)25-17-5-7-18(8-6-17)30(31)32/h1-8H,9-14H2,(H3,23,24,25,26,27,28)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179007 (6-(4-benzylpiperazin-1-yl)-N2,N4-bis(3,4-difluorop...) Show SMILES Fc1ccc(Nc2nc(Nc3ccc(F)c(F)c3)nc(n2)N2CCN(Cc3ccccc3)CC2)cc1F Show InChI InChI=1S/C26H23F4N7/c27-20-8-6-18(14-22(20)29)31-24-33-25(32-19-7-9-21(28)23(30)15-19)35-26(34-24)37-12-10-36(11-13-37)16-17-4-2-1-3-5-17/h1-9,14-15H,10-13,16H2,(H2,31,32,33,34,35)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178998 (1-(4-(4,6-bis(4-bromophenylamino)-1,3,5-triazin-2-...) Show SMILES CC(=O)c1ccc(Nc2nc(Nc3ccc(Br)cc3)nc(Nc3ccc(Br)cc3)n2)cc1 Show InChI InChI=1S/C23H18Br2N6O/c1-14(32)15-2-8-18(9-3-15)26-21-29-22(27-19-10-4-16(24)5-11-19)31-23(30-21)28-20-12-6-17(25)7-13-20/h2-13H,1H3,(H3,26,27,28,29,30,31)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178999 (2-(4-(4,6-bis(3,4-difluorophenylamino)-1,3,5-triaz...) Show SMILES OCCN1CCN(CC1)c1nc(Nc2ccc(F)c(F)c2)nc(Nc2ccc(F)c(F)c2)n1 Show InChI InChI=1S/C21H21F4N7O/c22-15-3-1-13(11-17(15)24)26-19-28-20(27-14-2-4-16(23)18(25)12-14)30-21(29-19)32-7-5-31(6-8-32)9-10-33/h1-4,11-12,33H,5-10H2,(H2,26,27,28,29,30)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178996 (CHEMBL203116 | N2,N4-bis(3,4-difluorophenyl)-N6-(2...) Show SMILES Fc1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc3ccc(F)c(F)c3)n2)cc1F Show InChI InChI=1S/C21H21F4N7O/c22-15-3-1-13(11-17(15)24)27-20-29-19(26-5-6-32-7-9-33-10-8-32)30-21(31-20)28-14-2-4-16(23)18(25)12-14/h1-4,11-12H,5-10H2,(H3,26,27,28,29,30,31)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179002 (CHEMBL202736 | N2,N4-bis(4-chlorophenyl)-N6-(2-mor...) Show SMILES Clc1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc3ccc(Cl)cc3)n2)cc1 Show InChI InChI=1S/C21H23Cl2N7O/c22-15-1-5-17(6-2-15)25-20-27-19(24-9-10-30-11-13-31-14-12-30)28-21(29-20)26-18-7-3-16(23)4-8-18/h1-8H,9-14H2,(H3,24,25,26,27,28,29)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179005 (CHEMBL204914 | N2,N4-bis(4-fluorophenyl)-6-(4-meth...) Show SMILES CN1CCN(CC1)c1nc(Nc2ccc(F)cc2)nc(Nc2ccc(F)cc2)n1 Show InChI InChI=1S/C20H21F2N7/c1-28-10-12-29(13-11-28)20-26-18(23-16-6-2-14(21)3-7-16)25-19(27-20)24-17-8-4-15(22)5-9-17/h2-9H,10-13H2,1H3,(H2,23,24,25,26,27)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178994 (2-(4-(4,6-bis(4-fluorophenylamino)-1,3,5-triazin-2...) Show SMILES OCCN1CCN(CC1)c1nc(Nc2ccc(F)cc2)nc(Nc2ccc(F)cc2)n1 Show InChI InChI=1S/C21H23F2N7O/c22-15-1-5-17(6-2-15)24-19-26-20(25-18-7-3-16(23)4-8-18)28-21(27-19)30-11-9-29(10-12-30)13-14-31/h1-8,31H,9-14H2,(H2,24,25,26,27,28)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178995 (CHEMBL381819 | N2,N4,N6-tris(3-chlorophenyl)-1,3,5...) Show SMILES Clc1cccc(Nc2nc(Nc3cccc(Cl)c3)nc(Nc3cccc(Cl)c3)n2)c1 Show InChI InChI=1S/C21H15Cl3N6/c22-13-4-1-7-16(10-13)25-19-28-20(26-17-8-2-5-14(23)11-17)30-21(29-19)27-18-9-3-6-15(24)12-18/h1-12H,(H3,25,26,27,28,29,30)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179006 (CHEMBL202792 | N2-(4-chlorophenyl)-N4-(2-morpholin...) Show SMILES Clc1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc3ccccc3)n2)cc1 Show InChI InChI=1S/C21H24ClN7O/c22-16-6-8-18(9-7-16)25-21-27-19(23-10-11-29-12-14-30-15-13-29)26-20(28-21)24-17-4-2-1-3-5-17/h1-9H,10-15H2,(H3,23,24,25,26,27,28)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178997 (CHEMBL380861 | N2,N4-bis(4-fluorophenyl)-N6-(2-mor...) Show SMILES Fc1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc3ccc(F)cc3)n2)cc1 Show InChI InChI=1S/C21H23F2N7O/c22-15-1-5-17(6-2-15)25-20-27-19(24-9-10-30-11-13-31-14-12-30)28-21(29-20)26-18-7-3-16(23)4-8-18/h1-8H,9-14H2,(H3,24,25,26,27,28,29)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50178993 (CHEMBL204595 | N-(2-morpholinoethyl)-N',N''-diphen...) Show SMILES C(CN1CCOCC1)Nc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1 Show InChI InChI=1S/C21H25N7O/c1-3-7-17(8-4-1)23-20-25-19(22-11-12-28-13-15-29-16-14-28)26-21(27-20)24-18-9-5-2-6-10-18/h1-10H,11-16H2,(H3,22,23,24,25,26,27)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair
Replicative DNA helicase (Pseudomonas aeruginosa)	BDBM50179003 (CHEMBL203487 | N2,N4-bis(4-methoxyphenyl)-N6-(2-mo...) Show SMILES COc1ccc(Nc2nc(NCCN3CCOCC3)nc(Nc3ccc(OC)cc3)n2)cc1 Show InChI InChI=1S/C23H29N7O3/c1-31-19-7-3-17(4-8-19)25-22-27-21(24-11-12-30-13-15-33-16-14-30)28-23(29-22)26-18-5-9-20(32-2)10-6-18/h3-10H,11-16H2,1-2H3,(H3,24,25,26,27,28,29)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Targanta Therapeutics Inc. Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa DnaB helicase				Bioorg Med Chem Lett 16: 1286-90 (2006) Article DOI: 10.1016/j.bmcl.2005.11.076 BindingDB Entry DOI: 10.7270/Q2PG1R95
					More data for this Ligand-Target Pair