Found 65 hits with Last Name = 'smart' and Initial = 'd' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218750
(CHEMBL299498)Show InChI InChI=1S/C19H16N4O/c1-23-11-9-13-12-14(6-7-18(13)23)21-19(24)22-17-8-10-20-16-5-3-2-4-15(16)17/h2-12H,1H3,(H2,20,21,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218751
(CHEMBL300835)Show InChI InChI=1S/C20H18N4O/c1-13-11-14-12-15(7-8-19(14)24(13)2)22-20(25)23-18-9-10-21-17-6-4-3-5-16(17)18/h3-12H,1-2H3,(H2,21,22,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM50219319
(CHEMBL438925)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CSSC[C@@H]2NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC2=O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(N)=O Show InChI InChI=1S/C152H243N47O44S4/c1-20-76(14)118(146(239)188-96(51-74(10)11)138(231)197-119(80(18)201)147(240)180-92(121(156)214)47-70(2)3)195-115(209)62-166-123(216)78(16)171-124(217)79(17)172-131(224)99(55-84-59-162-69-169-84)186-136(229)100(56-111(155)205)174-114(208)61-165-122(215)77(15)170-113(207)60-167-125(218)98(54-83-58-161-68-168-83)185-134(227)95(50-73(8)9)183-132(225)93(48-71(4)5)182-129(222)90(38-41-116(210)211)179-135(228)97(53-82-32-34-85(203)35-33-82)184-133(226)94(49-72(6)7)181-127(220)88(29-24-44-164-152(159)160)177-140(233)104-64-244-245-65-105-141(234)176-87(28-23-43-163-151(157)158)126(219)178-89(36-39-110(154)204)128(221)175-86(27-21-22-42-153)130(223)196-120(81(19)202)148(241)194-107(142(235)190-103(63-200)139(232)192-104)67-247-246-66-106(143(236)193-105)191-137(230)101(57-117(212)213)187-144(237)108-30-26-46-199(108)150(243)102(52-75(12)13)189-145(238)109-31-25-45-198(109)149(242)91-37-40-112(206)173-91/h32-35,58-59,68-81,86-109,118-120,200-203H,20-31,36-57,60-67,153H2,1-19H3,(H2,154,204)(H2,155,205)(H2,156,214)(H,161,168)(H,162,169)(H,165,215)(H,166,216)(H,167,218)(H,170,207)(H,171,217)(H,172,224)(H,173,206)(H,174,208)(H,175,221)(H,176,234)(H,177,233)(H,178,219)(H,179,228)(H,180,240)(H,181,220)(H,182,222)(H,183,225)(H,184,226)(H,185,227)(H,186,229)(H,187,237)(H,188,239)(H,189,238)(H,190,235)(H,191,230)(H,192,232)(H,193,236)(H,194,241)(H,195,209)(H,196,223)(H,197,231)(H,210,211)(H,212,213)(H4,157,158,163)(H4,159,160,164)/t76-,77-,78-,79-,80+,81+,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,118-,119-,120-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometry |
Bioorg Med Chem Lett 11: 737-40 (2001)
BindingDB Entry DOI: 10.7270/Q2988955 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218748
(CHEMBL301209)Show InChI InChI=1S/C19H18N4O/c1-23-11-9-13-12-14(6-7-18(13)23)21-19(24)22-17-8-10-20-16-5-3-2-4-15(16)17/h2-8,10,12H,9,11H2,1H3,(H2,20,21,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218752
(CHEMBL56557)Show InChI InChI=1S/C17H14ClN3O2/c1-23-16-7-6-11(10-13(16)18)20-17(22)21-15-8-9-19-14-5-3-2-4-12(14)15/h2-10H,1H3,(H2,19,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218750
(CHEMBL299498)Show InChI InChI=1S/C19H16N4O/c1-23-11-9-13-12-14(6-7-18(13)23)21-19(24)22-17-8-10-20-16-5-3-2-4-15(16)17/h2-12H,1H3,(H2,20,21,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218749
(CHEMBL54062)Show InChI InChI=1S/C17H15N3OS/c1-22-13-8-6-12(7-9-13)19-17(21)20-16-10-11-18-15-5-3-2-4-14(15)16/h2-11H,1H3,(H2,18,19,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218745
(CHEMBL57135)Show InChI InChI=1S/C20H22N4O/c1-3-24(4-2)16-11-9-15(10-12-16)22-20(25)23-19-13-14-21-18-8-6-5-7-17(18)19/h5-14H,3-4H2,1-2H3,(H2,21,22,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218749
(CHEMBL54062)Show InChI InChI=1S/C17H15N3OS/c1-22-13-8-6-12(7-9-13)19-17(21)20-16-10-11-18-15-5-3-2-4-14(15)16/h2-11H,1H3,(H2,18,19,20,21) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218748
(CHEMBL301209)Show InChI InChI=1S/C19H18N4O/c1-23-11-9-13-12-14(6-7-18(13)23)21-19(24)22-17-8-10-20-16-5-3-2-4-15(16)17/h2-8,10,12H,9,11H2,1H3,(H2,20,21,22,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218745
(CHEMBL57135)Show InChI InChI=1S/C20H22N4O/c1-3-24(4-2)16-11-9-15(10-12-16)22-20(25)23-19-13-14-21-18-8-6-5-7-17(18)19/h5-14H,3-4H2,1-2H3,(H2,21,22,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218752
(CHEMBL56557)Show InChI InChI=1S/C17H14ClN3O2/c1-23-16-7-6-11(10-13(16)18)20-17(22)21-15-8-9-19-14-5-3-2-4-12(14)15/h2-10H,1H3,(H2,19,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218751
(CHEMBL300835)Show InChI InChI=1S/C20H18N4O/c1-13-11-14-12-15(7-8-19(14)24(13)2)22-20(25)23-18-9-10-21-17-6-4-3-5-16(17)18/h3-12H,1-2H3,(H2,21,22,23,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218747
(CHEMBL417753)Show InChI InChI=1S/C18H18N4O/c1-22(2)14-9-7-13(8-10-14)20-18(23)21-17-11-12-19-16-6-4-3-5-15(16)17/h3-12H,1-2H3,(H2,19,20,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218747
(CHEMBL417753)Show InChI InChI=1S/C18H18N4O/c1-22(2)14-9-7-13(8-10-14)20-18(23)21-17-11-12-19-16-6-4-3-5-15(16)17/h3-12H,1-2H3,(H2,19,20,21,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM50445184
(CHEMBL412459)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(N)=O Show InChI InChI=1S/C91H148N28O24/c1-17-48(12)73(89(142)117-63(31-47(10)11)88(141)119-74(52(16)120)90(143)110-59(75(94)128)27-43(2)3)118-71(125)40-101-77(130)50(14)106-78(131)51(15)107-82(135)66(34-55-37-98-42-104-55)116-87(140)67(35-68(93)122)108-70(124)39-100-76(129)49(13)105-69(123)38-102-80(133)65(33-54-36-97-41-103-54)115-85(138)62(30-46(8)9)113-84(137)61(29-45(6)7)112-81(134)58(24-25-72(126)127)109-86(139)64(32-53-20-22-56(121)23-21-53)114-83(136)60(28-44(4)5)111-79(132)57(92)19-18-26-99-91(95)96/h20-23,36-37,41-52,57-67,73-74,120-121H,17-19,24-35,38-40,92H2,1-16H3,(H2,93,122)(H2,94,128)(H,97,103)(H,98,104)(H,100,129)(H,101,130)(H,102,133)(H,105,123)(H,106,131)(H,107,135)(H,108,124)(H,109,139)(H,110,143)(H,111,132)(H,112,134)(H,113,137)(H,114,136)(H,115,138)(H,116,140)(H,117,142)(H,118,125)(H,119,141)(H,126,127)(H4,95,96,99)/t48-,49-,50-,51-,52+,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,73-,74-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 269 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometry |
Bioorg Med Chem Lett 11: 737-40 (2001)
BindingDB Entry DOI: 10.7270/Q2988955 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50218746
(CHEMBL59266)Show InChI InChI=1S/C18H14N4O2/c1-11-20-16-7-6-12(10-17(16)24-11)21-18(23)22-15-8-9-19-14-5-3-2-4-13(14)15/h2-10H,1H3,(H2,19,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50218746
(CHEMBL59266)Show InChI InChI=1S/C18H14N4O2/c1-11-20-16-7-6-12(10-17(16)24-11)21-18(23)22-15-8-9-19-14-5-3-2-4-13(14)15/h2-10H,1H3,(H2,19,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50384416
(CHEMBL2111553 | CHEMBL291536 | SB-334867)Show InChI InChI=1S/C17H13N5O2/c1-10-20-12-5-4-11(9-15(12)24-10)21-17(23)22-14-6-8-18-13-3-2-7-19-16(13)14/h2-9H,1H3,(H2,18,21,22,23) | PDB
Reactome pathway
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PDB
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Similars
| PubMed
| 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2B receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50384416
(CHEMBL2111553 | CHEMBL291536 | SB-334867)Show InChI InChI=1S/C17H13N5O2/c1-10-20-12-5-4-11(9-15(12)24-10)21-17(23)22-14-6-8-18-13-3-2-7-19-16(13)14/h2-9H,1H3,(H2,18,21,22,23) | PDB
Reactome pathway
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UniChem
Similars
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| <5.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity against 5-hydroxytryptamine 2C receptor |
Bioorg Med Chem Lett 11: 1907-10 (2001)
BindingDB Entry DOI: 10.7270/Q2G16318 |
More data for this
Ligand-Target Pair | |
Orexin/Hypocretin receptor type 1
(Homo sapiens (Human)) | BDBM50219318
(CHEMBL262404)Show SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(N)=O Show InChI InChI=1S/C70H116N22O20/c1-15-36(10)56(69(111)90-47(21-35(8)9)68(110)92-57(40(14)93)70(112)85-44(58(73)100)18-32(2)3)91-54(97)29-77-60(102)38(12)82-61(103)39(13)83-64(106)49(23-42-26-75-31-80-42)89-67(109)50(24-51(72)94)84-53(96)28-76-59(101)37(11)81-52(95)27-78-63(105)48(22-41-25-74-30-79-41)88-66(108)46(20-34(6)7)87-65(107)45(19-33(4)5)86-62(104)43(71)16-17-55(98)99/h25-26,30-40,43-50,56-57,93H,15-24,27-29,71H2,1-14H3,(H2,72,94)(H2,73,100)(H,74,79)(H,75,80)(H,76,101)(H,77,102)(H,78,105)(H,81,95)(H,82,103)(H,83,106)(H,84,96)(H,85,112)(H,86,104)(H,87,107)(H,88,108)(H,89,109)(H,90,111)(H,91,97)(H,92,110)(H,98,99)/t36-,37-,38-,39-,40+,43-,44-,45-,46-,47-,48-,49-,50-,56-,57-/m0/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
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| 6.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals
Curated by ChEMBL
| Assay Description
Binding affinity to Orexin receptor type 1 was determined using laser scanning cytometry |
Bioorg Med Chem Lett 11: 737-40 (2001)
BindingDB Entry DOI: 10.7270/Q2988955 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20469
(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-phenylur...)Show InChI InChI=1S/C18H23N3O/c1-3-21(17-11-7-8-15(2)14-17)13-12-19-18(22)20-16-9-5-4-6-10-16/h4-11,14H,3,12-13H2,1-2H3,(H2,19,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20470
(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-(2-methy...)Show InChI InChI=1S/C19H25N3O/c1-4-22(17-10-7-8-15(2)14-17)13-12-20-19(23)21-18-11-6-5-9-16(18)3/h5-11,14H,4,12-13H2,1-3H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20471
(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-(2-fluor...)Show InChI InChI=1S/C18H22FN3O/c1-3-22(15-8-6-7-14(2)13-15)12-11-20-18(23)21-17-10-5-4-9-16(17)19/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 158 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20472
(1-(2-chlorophenyl)-3-{2-[ethyl(3-methylphenyl)amin...)Show InChI InChI=1S/C18H22ClN3O/c1-3-22(15-8-6-7-14(2)13-15)12-11-20-18(23)21-17-10-5-4-9-16(17)19/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20468
(3-(2-bromophenyl)-1-{2-[ethyl(3-methylphenyl)amino...)Show InChI InChI=1S/C18H22BrN3O/c1-3-22(15-8-6-7-14(2)13-15)12-11-20-18(23)21-17-10-5-4-9-16(17)19/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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| Purchase
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20473
(1-(3-bromophenyl)-3-{2-[ethyl(3-methylphenyl)amino...)Show InChI InChI=1S/C18H22BrN3O/c1-3-22(17-9-4-6-14(2)12-17)11-10-20-18(23)21-16-8-5-7-15(19)13-16/h4-9,12-13H,3,10-11H2,1-2H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20474
(1-(4-bromophenyl)-3-{2-[ethyl(3-methylphenyl)amino...)Show InChI InChI=1S/C18H22BrN3O/c1-3-22(17-6-4-5-14(2)13-17)12-11-20-18(23)21-16-9-7-15(19)8-10-16/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20475
(3-{2-[ethyl(3-methylphenyl)amino]ethyl}-1-naphthal...)Show InChI InChI=1S/C22H25N3O/c1-3-25(19-11-6-8-17(2)16-19)15-14-23-22(26)24-21-13-7-10-18-9-4-5-12-20(18)21/h4-13,16H,3,14-15H2,1-2H3,(H2,23,24,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20476
(1-(2,3-dichlorophenyl)-3-{2-[ethyl(3-methylphenyl)...)Show InChI InChI=1S/C18H21Cl2N3O/c1-3-23(14-7-4-6-13(2)12-14)11-10-21-18(24)22-16-9-5-8-15(19)17(16)20/h4-9,12H,3,10-11H2,1-2H3,(H2,21,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20477
(1-(2,5-dichlorophenyl)-3-{2-[ethyl(3-methylphenyl)...)Show InChI InChI=1S/C18H21Cl2N3O/c1-3-23(15-6-4-5-13(2)11-15)10-9-21-18(24)22-17-12-14(19)7-8-16(17)20/h4-8,11-12H,3,9-10H2,1-2H3,(H2,21,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20478
(1-(2-bromophenyl)-3-{2-[(3-methylphenyl)amino]ethy...)Show InChI InChI=1S/C16H18BrN3O/c1-12-5-4-6-13(11-12)18-9-10-19-16(21)20-15-8-3-2-7-14(15)17/h2-8,11,18H,9-10H2,1H3,(H2,19,20,21) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >158 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20479
(1-(2-bromophenyl)-3-{2-[methyl(3-methylphenyl)amin...)Show InChI InChI=1S/C17H20BrN3O/c1-13-6-5-7-14(12-13)21(2)11-10-19-17(22)20-16-9-4-3-8-15(16)18/h3-9,12H,10-11H2,1-2H3,(H2,19,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20480
(1-{2-[benzyl(3-methylphenyl)amino]ethyl}-3-(2-brom...)Show InChI InChI=1S/C23H24BrN3O/c1-18-8-7-11-20(16-18)27(17-19-9-3-2-4-10-19)15-14-25-23(28)26-22-13-6-5-12-21(22)24/h2-13,16H,14-15,17H2,1H3,(H2,25,26,28) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >200 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20481
(N-(2-{[(2-bromophenyl)carbamoyl]amino}ethyl)-N-(3-...)Show InChI InChI=1S/C18H20BrN3O2/c1-13-6-5-7-15(12-13)22(14(2)23)11-10-20-18(24)21-17-9-4-3-8-16(17)19/h3-9,12H,10-11H2,1-2H3,(H2,20,21,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >251 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20482
(1-(2-bromophenyl)-3-{2-[ethyl(phenyl)amino]ethyl}u...)Show InChI InChI=1S/C17H20BrN3O/c1-2-21(14-8-4-3-5-9-14)13-12-19-17(22)20-16-11-7-6-10-15(16)18/h3-11H,2,12-13H2,1H3,(H2,19,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 63 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20483
(1-(2-bromophenyl)-3-{2-[ethyl(2-methylphenyl)amino...)Show InChI InChI=1S/C18H22BrN3O/c1-3-22(17-11-7-4-8-14(17)2)13-12-20-18(23)21-16-10-6-5-9-15(16)19/h4-11H,3,12-13H2,1-2H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20484
(1-(2-bromophenyl)-3-{2-[ethyl(4-methylphenyl)amino...)Show InChI InChI=1S/C18H22BrN3O/c1-3-22(15-10-8-14(2)9-11-15)13-12-20-18(23)21-17-7-5-4-6-16(17)19/h4-11H,3,12-13H2,1-2H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 8 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20485
(1-(2-bromophenyl)-3-{2-[ethyl(3-fluorophenyl)amino...)Show InChI InChI=1S/C17H19BrFN3O/c1-2-22(14-7-5-6-13(19)12-14)11-10-20-17(23)21-16-9-4-3-8-15(16)18/h3-9,12H,2,10-11H2,1H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 25 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20486
(1-(2-bromophenyl)-3-{2-[(3,4-difluorophenyl)(ethyl...)Show InChI InChI=1S/C17H18BrF2N3O/c1-2-23(12-7-8-14(19)15(20)11-12)10-9-21-17(24)22-16-6-4-3-5-13(16)18/h3-8,11H,2,9-10H2,1H3,(H2,21,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 16 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20487
(1-(2-bromophenyl)-3-{2-[ethyl(3-fluoro-4-methylphe...)Show InChI InChI=1S/C18H21BrFN3O/c1-3-23(14-9-8-13(2)16(20)12-14)11-10-21-18(24)22-17-7-5-4-6-15(17)19/h4-9,12H,3,10-11H2,1-2H3,(H2,21,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 6 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20488
((2E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-...)Show InChI InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20284
(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)Show InChI InChI=1S/C19H21ClN2O2S/c20-16-5-3-13(4-6-16)7-8-21-19(25)22-9-1-2-14-10-17(23)18(24)11-15(14)12-22/h3-6,10-11,23-24H,1-2,7-9,12H2,(H,21,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
PubMed
| n/a | n/a | n/a | n/a | 32 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20489
(1-(2-bromophenyl)-3-{2-[ethyl(methyl)(3-methylphen...)Show InChI InChI=1S/C19H24BrN3O/c1-4-23(3,16-9-7-8-15(2)14-16)13-12-21-19(24)22-18-11-6-5-10-17(18)20/h5-11,14H,4,12-13H2,1-3H3,(H-,21,22,24)/p+1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 100 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 14: 3631-4 (2004)
Article DOI: 10.1016/j.bmcl.2004.05.028
BindingDB Entry DOI: 10.7270/Q24T6GM8 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20490
(1-(2-bromophenyl)-3-[2-(2,3-dihydro-1H-indol-1-yl)...)Show InChI InChI=1S/C17H18BrN3O/c18-14-6-2-3-7-15(14)20-17(22)19-10-12-21-11-9-13-5-1-4-8-16(13)21/h1-8H,9-12H2,(H2,19,20,22) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 158 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 16: 3287-91 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.030
BindingDB Entry DOI: 10.7270/Q2125QX9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20491
(1-(2-bromophenyl)-3-[2-(4-methyl-2,3-dihydro-1H-in...)Show InChI InChI=1S/C18H20BrN3O/c1-13-5-4-8-17-14(13)9-11-22(17)12-10-20-18(23)21-16-7-3-2-6-15(16)19/h2-8H,9-12H2,1H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 16: 3287-91 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.030
BindingDB Entry DOI: 10.7270/Q2125QX9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20492
(1-(2-bromophenyl)-3-[2-(5-methyl-2,3-dihydro-1H-in...)Show InChI InChI=1S/C18H20BrN3O/c1-13-6-7-17-14(12-13)8-10-22(17)11-9-20-18(23)21-16-5-3-2-4-15(16)19/h2-7,12H,8-11H2,1H3,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 16: 3287-91 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.030
BindingDB Entry DOI: 10.7270/Q2125QX9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20493
(1-(2-bromophenyl)-3-[2-(4-fluoro-2,3-dihydro-1H-in...)Show InChI InChI=1S/C17H17BrFN3O/c18-13-4-1-2-6-15(13)21-17(23)20-9-11-22-10-8-12-14(19)5-3-7-16(12)22/h1-7H,8-11H2,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 16: 3287-91 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.030
BindingDB Entry DOI: 10.7270/Q2125QX9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20494
(1-(2-bromophenyl)-3-[2-(5-fluoro-2,3-dihydro-1H-in...)Show InChI InChI=1S/C17H17BrFN3O/c18-14-3-1-2-4-15(14)21-17(23)20-8-10-22-9-7-12-11-13(19)5-6-16(12)22/h1-6,11H,7-10H2,(H2,20,21,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 79 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 16: 3287-91 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.030
BindingDB Entry DOI: 10.7270/Q2125QX9 |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM20495
(3-(2-bromophenyl)-1-[2-(6-methyl-1,2,3,4-tetrahydr...)Show InChI InChI=1S/C19H22BrN3O/c1-14-8-9-18-15(13-14)5-4-11-23(18)12-10-21-19(24)22-17-7-3-2-6-16(17)20/h2-3,6-9,13H,4-5,10-12H2,1H3,(H2,21,22,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 40 | n/a | n/a | 7.2 | 25 |
GSK
| Assay Description
One day before the assay was performed, human TRPV1 expressed in 1321N1 astrocytoma cells were plated onto 96-well assay plates and grown until 2.5 h... |
Bioorg Med Chem Lett 16: 3287-91 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.030
BindingDB Entry DOI: 10.7270/Q2125QX9 |
More data for this
Ligand-Target Pair | |
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