BindingDB PrimarySearch

Found 1770 hits with Last Name = 'teng' and Initial = 'm'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286349 (US11220518, Ex. No. K7 \| US11780853, Example K7 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.165	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286349 (US11220518, Ex. No. K7 \| US11780853, Example K7 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.165	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286349 (US11220518, Ex. No. K7 \| US11780853, Example K7 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.165	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222915 (4'-[5-(4-pyrrolidin-1-ylmethyl-phenylamino)-1H-pyr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286350 (US11220518, Ex. No. K8 \| US11780853, Example K8 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286350 (US11220518, Ex. No. K8 \| US11780853, Example K8 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286350 (US11220518, Ex. No. K8 \| US11780853, Example K8 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.181	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222916 (4'-{5-[4-(dimethylamino-methyl)-phenylamino]-2H-py...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222920 (4'-{5-[6-(sec-butylamino-methyl)-pyridin-3-ylamino...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222917 (4'-[5-(6-piperidin-1-ylmethyl-pyridin-3-ylamino)-1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222913 (4'-{5-[4-(isopropylamino-methyl)-phenylamino]-2H-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286348 (US11220518, Ex. No. K6 \| US11780853, Example K6 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.376	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286348 (US11220518, Ex. No. K6 \| US11780853, Example K6 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.376	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286348 (US11220518, Ex. No. K6 \| US11780853, Example K6 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.376	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222914 (4'-[5-(4-cyclopropylaminomethyl-phenylamino)-2H-py...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222921 (3-(1H-benzo[d]imidazol-2-yl)-N-(2,4-dihydroxypheny...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286347 (US11220518, Ex. No. K5 \| US11780853, Example K5 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.683	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286347 (US11220518, Ex. No. K5 \| US11780853, Example K5 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.683	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286347 (US11220518, Ex. No. K5 \| US11780853, Example K5 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.683	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Threonine--tRNA ligase (Yersinia pestis)	BDBM50426188 (CHEMBL2311920) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trius Therapeutics, Inc. Curated by ChEMBL					Assay Description Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometry				J Med Chem 56: 1748-60 (2013) Article DOI: 10.1021/jm301756m BindingDB Entry DOI: 10.7270/Q2GQ7036
Trius Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222919 (4'-(5-{6-[(cyclopropylmethyl-amino)-methyl]-pyridi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286345 (US11220518, Ex. No. K3 \| US11780853, Example K3 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286345 (US11220518, Ex. No. K3 \| US11780853, Example K3 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286345 (US11220518, Ex. No. K3 \| US11780853, Example K3 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.912	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286246 (5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286246 (5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.01	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286246 (5-{[(8S)-6,8-dimethyl-6,9-diazaspiro[4.5]dec-9-yl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		1.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM533472 (US11220518, Ex. No. K1 \| US11780853, Example K1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286343 (N-(2-ethoxy-5-fluoropyrimidin-4-yl)-6,6-dimethyl-5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.12	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM533472 (US11220518, Ex. No. K1 \| US11780853, Example K1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		1.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286320 (US9518060, Example J6) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.17	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM533459 (US11220518, Ex. No. J6 \| US11780853, Example J6) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		1.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM533459 (US11220518, Ex. No. J6 \| US11780853, Example J6) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Threonine--tRNA ligase 1, cytoplasmic (Homo sapiens (Human))	BDBM50426188 (CHEMBL2311920) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trius Therapeutics, Inc. Curated by ChEMBL					Assay Description Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometry				J Med Chem 56: 1748-60 (2013) Article DOI: 10.1021/jm301756m BindingDB Entry DOI: 10.7270/Q2GQ7036
Trius Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50222918 (4'-(5-phenylamino-2H-pyrazol-3-yl)-biphenyl-2,4-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human CHK1 expressed in baculovirus/insect cell system				J Med Chem 50: 5253-6 (2007) Article DOI: 10.1021/jm0704604 BindingDB Entry DOI: 10.7270/Q2K0754D
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286270 (US11220518, Ex. No. E2 \| US11780853, Example E2 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286270 (US11220518, Ex. No. E2 \| US11780853, Example E2 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		1.64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286270 (US11220518, Ex. No. E2 \| US11780853, Example E2 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.64	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM153901 (US8999981, A146) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.70	-50.9	n/a	n/a	n/a	n/a	n/a	7.4	30
Pfizer Inc.; Pfizer Products Inc. US Patent					Assay Description Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US8999981 (2015) BindingDB Entry DOI: 10.7270/Q2RR1X0K
Pfizer Inc.; Pfizer Products Inc. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM286377 (US11220518, Ex. No. L4 \| US11780853, Example L4 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		1.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286377 (US11220518, Ex. No. L4 \| US11780853, Example L4 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.71	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM286377 (US11220518, Ex. No. L4 \| US11780853, Example L4 \| ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein-tyrosine kinase 2-beta (Homo sapiens (Human))	BDBM286310 (N-(5-fluoro-2-propylpyrimidin-4-yl)-6,6-dimethyl-5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.73	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PFIZER INC. US Patent					Assay Description Protein Kinase C beta 2 (PKCβII) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US9518060 (2016) BindingDB Entry DOI: 10.7270/Q2ZK5JPN
PFIZER INC. US Patent					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM533452 (US11220518, Ex. No. I1 \| US11780853, Example I1) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description A typical assay was carried out on a 96-well, clear microtiter plate in a Molecular Devices spectrophotometer for 20 minutes at 30� C. in 0.1 mL of a...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T3T
TBA					More data for this Ligand-Target Pair
Protein kinase C beta type Isoform 2 (Homo sapiens (Human))	BDBM533452 (US11220518, Ex. No. I1 \| US11780853, Example I1) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		1.73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Threonine--tRNA ligase (Yersinia pestis)	BDBM50426183 (CHEMBL2311925) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trius Therapeutics, Inc. Curated by ChEMBL					Assay Description Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometry				J Med Chem 56: 1748-60 (2013) Article DOI: 10.1021/jm301756m BindingDB Entry DOI: 10.7270/Q2GQ7036
Trius Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Threonine--tRNA ligase (Yersinia pestis)	BDBM50426182 (CHEMBL2311926) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trius Therapeutics, Inc. Curated by ChEMBL					Assay Description Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometry				J Med Chem 56: 1748-60 (2013) Article DOI: 10.1021/jm301756m BindingDB Entry DOI: 10.7270/Q2GQ7036
Trius Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Threonine--tRNA ligase 1, cytoplasmic (Homo sapiens (Human))	BDBM50426182 (CHEMBL2311926) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trius Therapeutics, Inc. Curated by ChEMBL					Assay Description Binding affinity to human cytoplasmic ThrRS by coupled spectrophotometry				J Med Chem 56: 1748-60 (2013) Article DOI: 10.1021/jm301756m BindingDB Entry DOI: 10.7270/Q2GQ7036
Trius Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Protein kinase C beta type (Homo sapiens (Human))	BDBM153898 (US8999981, A143) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	1.90	-50.6	n/a	n/a	n/a	n/a	n/a	7.4	30
Pfizer Inc.; Pfizer Products Inc. US Patent					Assay Description Protein Kinase C beta 2 (PKC beta II) catalyzes the production of ADP from ATP that accompanies the phosphoryl transfer to the PKC Pseudosubstrate pe...				US Patent US8999981 (2015) BindingDB Entry DOI: 10.7270/Q2RR1X0K
Pfizer Inc.; Pfizer Products Inc. US Patent					More data for this Ligand-Target Pair
Threonine--tRNA ligase (Yersinia pestis)	BDBM50426184 (CHEMBL2311924) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trius Therapeutics, Inc. Curated by ChEMBL					Assay Description Binding affinity to Yersinia pestis ThrRS by coupled spectrophotometry				J Med Chem 56: 1748-60 (2013) Article DOI: 10.1021/jm301756m BindingDB Entry DOI: 10.7270/Q2GQ7036
Trius Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

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