Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50145347 (1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridi...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145347 (1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50451852 (CHEMBL1159649) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145355 (1-{2-[4-(6,7-Dichloro-1H-indol-3-yl)-3,6-dihydro-2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145343 (1-{2-[4-(6-Fluoro-benzofuran-3-yl)-3,6-dihydro-2H-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50366907 (CHEMBL1169435) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145356 (1-{2-[4-(6,7-Difluoro-1H-indol-3-yl)-3,6-dihydro-2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145342 (1-{2-[4-(6-Chloro-1H-indol-3-yl)-3,6-dihydro-2H-py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145354 (1-{2-[4-(6-Fluoro-1H-indazol-3-yl)-3,6-dihydro-2H-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145350 (1-{2-[4-(6-Fluoro-1-methyl-1H-indazol-3-yl)-3,6-di...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145349 (1-{2-[4-(7-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145338 (1-{2-[(S)-4-(6-Fluoro-1H-indol-3-yl)-2-methyl-pipe...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50210638 (1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpipe...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50210642 ((S)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methylp...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]GR125743 from human 5HT1D expressed in LM(tk-) cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145344 (1-{2-[4-(6-Fluoro-1-methyl-1H-indol-3-yl)-3,6-dihy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.980 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145346 (1-{2-[4-(6-Trifluoromethyl-1H-indol-3-yl)-3,6-dihy...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.990 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145336 (1-{2-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-3,6-dihyd...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50210635 ((S)-1-(2-(4-(6-cyanonaphthalen-1-yl)piperazin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]GR125743 from human 5HT1D expressed in LM(tk-) cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50145352 (1-{2-[3-(6-Fluoro-1H-indol-3-yl)-pyrrolidin-1-yl]-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50210640 ((1R)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50210637 ((1S)-1-(2-((S)-4-(6-fluoronaphthalen-1-yl)-2-methy...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145341 (1-{2-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50451852 (CHEMBL1159649) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50210640 ((1R)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]GR125743 from human 5HT1D expressed in LM(tk-) cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50451853 (CHEMBL2112307) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145337 (1-{2-[4-(6-Fluoro-1H-indol-3-yl)-piperidin-1-yl]-e...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50210641 ((S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145352 (1-{2-[3-(6-Fluoro-1H-indol-3-yl)-pyrrolidin-1-yl]-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145357 (1-{2-[4-(7-Cyano-1H-indol-3-yl)-3,6-dihydro-2H-pyr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50145341 (1-{2-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against dopamine receptor D2 in rat caudate membranes using [3H]- raclopride as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50145354 (1-{2-[4-(6-Fluoro-1H-indazol-3-yl)-3,6-dihydro-2H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145351 (1-{2-[4-(6-Fluoro-naphthalen-2-yl)-3,6-dihydro-2H-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50210642 ((S)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methylp...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50145343 (1-{2-[4-(6-Fluoro-benzofuran-3-yl)-3,6-dihydro-2H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50366907 (CHEMBL1169435) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50145339 (1-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-3,6-dihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50210633 ((S)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methyl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145333 (1-[2-(4-Naphthalen-1-yl-3,6-dihydro-2H-pyridin-1-y...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50145332 (1-{2-[4-(5-Methoxy-1H-indol-3-yl)-3,6-dihydro-2H-p...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranes | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50145349 (1-{2-[4-(7-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against dopamine receptor D2 in rat caudate membranes using [3H]- raclopride as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50145336 (1-{2-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-3,6-dihyd...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against dopamine receptor D2 in rat caudate membranes using [3H]- raclopride as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50145347 (1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against dopamine receptor D2 in rat caudate membranes using [3H]- raclopride as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50210638 (1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]raclopride from dopamine D2 receptor in rat caudate membranes | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50145333 (1-[2-(4-Naphthalen-1-yl-3,6-dihydro-2H-pyridin-1-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 1D receptor in L-M(tk-) cells using [3H]GR-125743 as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50210635 ((S)-1-(2-(4-(6-cyanonaphthalen-1-yl)piperazin-1-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human 5HT transpoter expressed in HEK293 cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50145334 (1-{2-[4-(6-Fluoro-1H-indol-3-yl)-piperazin-1-yl]-e...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against alpha-1 adrenergic receptor in rat cortex membranes using [3H]prazosin as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50074749 ((1R,4R,5S,6R)-4-Amino-2-oxa-bicyclo[3.1.0]hexane-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Ability to displace [3H]-LY-341,495 from recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells. | J Med Chem 42: 1027-40 (1999) Article DOI: 10.1021/jm980616n BindingDB Entry DOI: 10.7270/Q2WM1CKF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 3 (Homo sapiens (Human)) | BDBM50074749 ((1R,4R,5S,6R)-4-Amino-2-oxa-bicyclo[3.1.0]hexane-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Ability to displace [3H]-LY-341,495 from recombinant human Metabotropic glutamate receptor 3 expressed in RGT cells. | J Med Chem 42: 1027-40 (1999) Article DOI: 10.1021/jm980616n BindingDB Entry DOI: 10.7270/Q2WM1CKF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50145356 (1-{2-[4-(6,7-Difluoro-1H-indol-3-yl)-3,6-dihydro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Co. Ltd Curated by ChEMBL | Assay Description Binding affinity determined against dopamine receptor D2 in rat caudate membranes using [3H]- raclopride as radioligand | Bioorg Med Chem Lett 14: 2469-72 (2004) Article DOI: 10.1016/j.bmcl.2004.03.003 BindingDB Entry DOI: 10.7270/Q2057GG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50210633 ((S)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly SA Curated by ChEMBL | Assay Description Displacement of [3H]GR125743 from human 5HT1D expressed in LM(tk-) cells | Bioorg Med Chem Lett 17: 3344-8 (2007) Article DOI: 10.1016/j.bmcl.2007.03.101 BindingDB Entry DOI: 10.7270/Q20V8CG3 | |||||||||||
More data for this Ligand-Target Pair |
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