Found 210 hits Enz. Inhib. hit(s) with Target = 'Solute carrier family 22 member 6' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50350468
(CEFAMANDOLE)Show SMILES Cn1nnnc1SCC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](O)c1ccccc1)C2=O)C(O)=O |r,t:9| Show InChI InChI=1S/C18H18N6O5S2/c1-23-18(20-21-22-23)31-8-10-7-30-16-11(15(27)24(16)12(10)17(28)29)19-14(26)13(25)9-5-3-2-4-6-9/h2-6,11,13,16,25H,7-8H2,1H3,(H,19,26)(H,28,29)/t11-,13-,16-/m1/s1 | PDB
Reactome pathway KEGG
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| DrugBank PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50206441
(2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-6H-xanthen-9...)Show SMILES OC(=O)c1ccccc1-c1c2cc(Br)c(O)c(Br)c2oc2c(Br)c(=O)c(Br)cc12 |(32.53,-16.69,;33.02,-15.23,;32,-14.07,;34.53,-14.92,;34.52,-13.38,;35.85,-12.6,;37.19,-13.36,;37.2,-14.9,;35.87,-15.67,;35.87,-17.21,;37.21,-17.96,;38.54,-17.19,;39.88,-17.94,;41.21,-17.16,;39.89,-19.5,;41.23,-20.26,;38.56,-20.28,;38.57,-21.82,;37.22,-19.51,;35.88,-20.29,;34.55,-19.52,;33.22,-20.3,;33.22,-21.84,;31.88,-19.53,;30.55,-20.3,;31.88,-17.98,;30.56,-17.2,;33.22,-17.24,;34.55,-17.98,)| Show InChI InChI=1S/C20H8Br4O5/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25/h1-6,25H,(H,27,28) | PDB
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| 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50370587
(CEFAZOLIN)Show SMILES Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn2cnnn2)C3=O)C(O)=O)s1 |r,t:7| Show InChI InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1 | PDB
Reactome pathway KEGG
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| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50390999
(CEFOPERAZONE)Show SMILES CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O |c:26| Show InChI InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1 | PDB
Reactome pathway KEGG
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| 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM82898
((6R,7R)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)...)Show SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1cccs1)C2=O)C(O)=O |t:5| Show InChI InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1 | PDB
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| 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50049707
((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...)Show SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSc3nc(=O)c(=O)[nH]n3C)=C(N2C1=O)C(O)=O)c1csc(N)n1 |r,c:23| Show InChI InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1 | PDB
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| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50485601
(CHEMBL2075007)Show InChI InChI=1S/C13H17NO3S/c1-10(15)14-12(13(16)17-2)9-18-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,15)/t12-/m1/s1 | PDB
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| PC cid PC sid UniChem
| Article PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester School of Medicine and Dentistry
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 60: 1091-9 (2001)
Article DOI: 10.1124/mol.60.5.1091 BindingDB Entry DOI: 10.7270/Q2CN76RK |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50270022
(O2C(CH2)4CO2 dianion | adipate | adipate dianion |...)Show InChI InChI=1S/C6H10O4/c7-5(8)3-1-2-4-6(9)10/h1-4H2,(H,7,8)(H,9,10)/p-2 | PDB
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| Article PubMed
| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50350473
(Aliporina | CEFALORIDINE)Show SMILES [O-]C(=O)C1=C(C[n+]2ccccc2)CS[C@@H]2[C@@H](NC(=O)Cc3cccs3)C(=O)N12 |r,c:3| Show InChI InChI=1S/C19H17N3O4S2/c23-14(9-13-5-4-8-27-13)20-15-17(24)22-16(19(25)26)12(11-28-18(15)22)10-21-6-2-1-3-7-21/h1-8,15,18H,9-11H2,(H-,20,23,25,26)/t15-,18+/m0/s1 | PDB
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| 740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50485602
(CHEMBL2075010)Show InChI InChI=1S/C7H13NO3S/c1-3-12-4-6(7(10)11)8-5(2)9/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m1/s1 | PDB
Reactome pathway KEGG
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| KEGG PC cid PC sid UniChem
| Article PubMed
| 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester School of Medicine and Dentistry
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 60: 1091-9 (2001)
Article DOI: 10.1124/mol.60.5.1091 BindingDB Entry DOI: 10.7270/Q2CN76RK |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50012957
(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)Show SMILES COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1 Show InChI InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29) | PDB
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| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Eur J Pharmacol 398: 193-7 (2000)
BindingDB Entry DOI: 10.7270/Q24Q7W83 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50485603
(CHEBI:7426 | CHEMBL2074738)Show SMILES CC(=O)N[C@@H](CSc1ccc(cc1[N+]([O-])=O)[N+]([O-])=O)C(O)=O |r| Show InChI InChI=1S/C11H11N3O7S/c1-6(15)12-8(11(16)17)5-22-10-3-2-7(13(18)19)4-9(10)14(20)21/h2-4,8H,5H2,1H3,(H,12,15)(H,16,17)/t8-/m0/s1 | PDB
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| KEGG PC cid PC sid UniChem
| Article PubMed
| 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester School of Medicine and Dentistry
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 60: 1091-9 (2001)
Article DOI: 10.1124/mol.60.5.1091 BindingDB Entry DOI: 10.7270/Q2CN76RK |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50339185
((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)Show InChI InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 | PDB
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| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 55: 847-54 (1999)
BindingDB Entry DOI: 10.7270/Q28053WW |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50420231
(CHEMBL2074600)Show SMILES OS(=O)(=O)Oc1ccc(cc1)C1(OC(=O)c2c1c(Br)ccc2Br)c1ccc(OS(O)(=O)=O)cc1 Show InChI InChI=1S/C20H12Br2O10S2/c21-15-9-10-16(22)18-17(15)19(23)30-20(18,11-1-5-13(6-2-11)31-33(24,25)26)12-3-7-14(8-4-12)32-34(27,28)29/h1-10H,(H,24,25,26)(H,27,28,29) | PDB
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| CHEMBL KEGG PC cid PC sid UniChem
| PubMed
| 2.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tokyo
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Oat1-expressing LLC-PK1 cells |
J Pharmacol Exp Ther 300: 746-53 (2002)
BindingDB Entry DOI: 10.7270/Q2FQ9XW4 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50143424
(2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid | ...)Show SMILES OC(=O)c1ccccc1-c1c2ccc(O)cc2oc2cc(=O)ccc12 |(-6.39,-28.75,;-5.64,-30.09,;-6.42,-31.42,;-4.1,-30.1,;-4.09,-28.56,;-2.74,-27.79,;-1.41,-28.57,;-1.42,-30.11,;-2.76,-30.87,;-2.77,-32.41,;-1.43,-33.19,;-.1,-32.42,;1.23,-33.2,;1.22,-34.74,;2.54,-35.52,;-.12,-35.5,;-1.44,-34.73,;-2.78,-35.49,;-4.11,-34.72,;-5.43,-35.48,;-6.76,-34.72,;-8.09,-35.49,;-6.76,-33.18,;-5.43,-32.4,;-4.1,-33.18,)| Show InChI InChI=1S/C20H12O5/c21-11-5-7-15-17(9-11)25-18-10-12(22)6-8-16(18)19(15)13-3-1-2-4-14(13)20(23)24/h1-10,21H,(H,23,24) | PDB
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| 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50335523
((6R,7R)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-y...)Show SMILES CO\N=C(\C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C(O)=O)c1csc(N)n1 |r,c:16| Show InChI InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9+/t10-,14-/m1/s1 | PDB
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| 3.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM35847
((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 | PDB
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| 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50009859
((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)Show InChI InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) | PDB
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| 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 55: 847-54 (1999)
BindingDB Entry DOI: 10.7270/Q28053WW |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
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| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of MTX uptake in Xenopus laevis oocytes |
Eur J Pharmacol 409: 31-6 (2001)
BindingDB Entry DOI: 10.7270/Q20Z74JR |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | PDB
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| DrugBank PDB Article PubMed
| 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing CHO cells |
Anal Biochem 283: 49-55 (2000)
Article DOI: 10.1006/abio.2000.4633 BindingDB Entry DOI: 10.7270/Q2DR2ZC6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | PDB
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| DrugBank PDB Article PubMed
| 4.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cells |
Life Sci 69: 2123-35 (2001)
Article DOI: 10.1016/s0024-3205(01)01296-6 BindingDB Entry DOI: 10.7270/Q2XD14JB |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50009859
((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)Show InChI InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15) | PDB
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| Article PubMed
| 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50485608
(CHEBI:28837 | Caprylic acid | EDENOR C 8-98-100 | ...)Show InChI InChI=1S/C8H16O2/c1-2-3-4-5-6-7-8(9)10/h2-7H2,1H3,(H,9,10) | PDB
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| Article PubMed
| 5.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cells |
Life Sci 69: 2123-35 (2001)
Article DOI: 10.1016/s0024-3205(01)01296-6 BindingDB Entry DOI: 10.7270/Q2XD14JB |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM25903
(3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid |...)Show InChI InChI=1S/C17H20N2O5S/c1-2-3-9-19-14-10-12(17(20)21)11-15(25(18,22)23)16(14)24-13-7-5-4-6-8-13/h4-8,10-11,19H,2-3,9H2,1H3,(H,20,21)(H2,18,22,23) | PDB
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| 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
J Pharmacol Exp Ther 295: 261-5 (2000)
BindingDB Entry DOI: 10.7270/Q2W66N2S |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50240008
(Aminohippuric Acid | CHEBI:104011 | PAHA | Para-Am...)Show InChI InChI=1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13) | PDB
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| PDB Article PubMed
| 6.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cells |
Life Sci 69: 2123-35 (2001)
Article DOI: 10.1016/s0024-3205(01)01296-6 BindingDB Entry DOI: 10.7270/Q2XD14JB |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50270006
(2-(4-aminobenzamido)acetate | AMINOHIPPURATE)Show InChI InChI=1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13)/p-1 | PDB
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| Article PubMed
| 6.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human Oat1 expressed in Drosophila S2 cells |
Bioorg Med Chem 19: 3320-40 (2011)
Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50350467
(BL-S578 | CEFADROXIL | Cefadrops)Show SMILES CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)c1ccc(O)cc1)C2=O)C(O)=O |r,t:1| Show InChI InChI=1S/C16H17N3O5S/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24)/t10-,11-,15-/m1/s1 | PDB
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| DrugBank PubMed
| 6.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 438: 137-42 (2002)
BindingDB Entry DOI: 10.7270/Q2N87C2C |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | PDB
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| PDB Article PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50269998
((S)-2-((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochr...)Show SMILES C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C([O-])=O)c(O)c2C(=O)O1 |r| Show InChI InChI=1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/p-1/t10-,15+/m1/s1 | PDB
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| Article PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50270021
(glutarate | glutarate(2-) | pentanedioate)Show InChI InChI=1S/C5H8O4/c6-4(7)2-1-3-5(8)9/h1-3H2,(H,6,7)(H,8,9)/p-2 | PDB
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| Article PubMed
| 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50538736
(CHEMBL4640580)Show InChI InChI=1S/C14H10Br2N2O3/c15-9-5-8(6-10(16)13(9)19)14(20)18-3-4-21-12-1-2-17-7-11(12)18/h1-2,5-7,19H,3-4H2 | PDB
Reactome pathway KEGG
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| Article PubMed
| 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
West China Hospital of Sichuan University
Curated by ChEMBL
| Assay Description Inhibition of human OAT1 |
Eur J Med Chem 166: 186-196 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.043 BindingDB Entry DOI: 10.7270/Q20C50BS |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50003019
(8-(Hexahydro-2,5-methano-pentalen-3a-yl)-1,3-dipro...)Show SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C12CC3CC1CC(C2)C3 |THB:22:21:18:24.23.25,22:23:18:21.20| Show InChI InChI=1S/C20H28N4O2/c1-3-5-23-16-15(17(25)24(6-4-2)19(23)26)21-18(22-16)20-10-12-7-13(11-20)9-14(20)8-12/h12-14H,3-11H2,1-2H3,(H,21,22) | PDB
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| 7.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 419: 113-20 (2001)
BindingDB Entry DOI: 10.7270/Q2S183SP |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50485600
(CHEMBL2074714)Show SMILES CCCCC\C=C/C\C=C/C=C/C=C/[C@@H](SC[C@H](NC(C)=O)C(O)=O)[C@@H](O)CCCC(O)=O |r| Show InChI InChI=1S/C25H39NO6S/c1-3-4-5-6-7-8-9-10-11-12-13-14-17-23(22(28)16-15-18-24(29)30)33-19-21(25(31)32)26-20(2)27/h7-8,10-14,17,21-23,28H,3-6,9,15-16,18-19H2,1-2H3,(H,26,27)(H,29,30)(H,31,32)/b8-7-,11-10-,13-12+,17-14+/t21-,22-,23+/m0/s1 | PDB
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KEGG PC cid PC sid UniChem
| Article PubMed
| 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rochester School of Medicine and Dentistry
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 60: 1091-9 (2001)
Article DOI: 10.1124/mol.60.5.1091 BindingDB Entry DOI: 10.7270/Q2CN76RK |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50344967
(2-[(4-Isopropyl-cyclohexanecarbonyl)-amino]-3-phen...)Show SMILES CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](Cc1ccccc1)C(O)=O |r,wU:6.9,wD:12.12,3.2,(9.97,-8.16,;11.31,-7.39,;12.64,-8.16,;11.31,-5.85,;12.64,-5.08,;12.64,-3.53,;11.3,-2.78,;9.97,-3.55,;9.97,-5.08,;11.3,-1.24,;12.63,-.46,;9.96,-.47,;9.96,1.07,;8.62,1.83,;7.29,1.06,;5.95,1.82,;4.63,1.05,;4.62,-.49,;5.96,-1.27,;7.29,-.49,;11.29,1.84,;12.62,1.08,;11.28,3.38,)| Show InChI InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1 | PDB
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| 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Eur J Pharmacol 398: 193-7 (2000)
BindingDB Entry DOI: 10.7270/Q24Q7W83 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50344967
(2-[(4-Isopropyl-cyclohexanecarbonyl)-amino]-3-phen...)Show SMILES CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](Cc1ccccc1)C(O)=O |r,wU:6.9,wD:12.12,3.2,(9.97,-8.16,;11.31,-7.39,;12.64,-8.16,;11.31,-5.85,;12.64,-5.08,;12.64,-3.53,;11.3,-2.78,;9.97,-3.55,;9.97,-5.08,;11.3,-1.24,;12.63,-.46,;9.96,-.47,;9.96,1.07,;8.62,1.83,;7.29,1.06,;5.95,1.82,;4.63,1.05,;4.62,-.49,;5.96,-1.27,;7.29,-.49,;11.29,1.84,;12.62,1.08,;11.28,3.38,)| Show InChI InChI=1S/C19H27NO3/c1-13(2)15-8-10-16(11-9-15)18(21)20-17(19(22)23)12-14-6-4-3-5-7-14/h3-7,13,15-17H,8-12H2,1-2H3,(H,20,21)(H,22,23)/t15-,16-,17-/m1/s1 | PDB
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| Article PubMed
| 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of rat Oat1 expressed in Xenopus oocytes |
Bioorg Med Chem 19: 3320-40 (2011)
Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50270006
(2-(4-aminobenzamido)acetate | AMINOHIPPURATE)Show InChI InChI=1S/C9H10N2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(12)13/h1-4H,5,10H2,(H,11,14)(H,12,13)/p-1 | PDB
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| Article PubMed
| 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM25902
(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)Show InChI InChI=1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19) | PDB
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Patents
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| 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
J Pharmacol Exp Ther 295: 261-5 (2000)
BindingDB Entry DOI: 10.7270/Q2W66N2S |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
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| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 55: 847-54 (1999)
BindingDB Entry DOI: 10.7270/Q28053WW |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50328021
((2-Hydroxy-benzoylamino)-acetic acid | 2-(2-hydrox...)Show InChI InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13) | PDB
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| Article PubMed
| 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of rat Oat1 expressed in Xenopus oocytes |
Bioorg Med Chem 19: 3320-40 (2011)
Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50328021
((2-Hydroxy-benzoylamino)-acetic acid | 2-(2-hydrox...)Show InChI InChI=1S/C9H9NO4/c11-7-4-2-1-3-6(7)9(14)10-5-8(12)13/h1-4,11H,5H2,(H,10,14)(H,12,13) | PDB
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| 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Mol Pharmacol 55: 847-54 (1999)
BindingDB Entry DOI: 10.7270/Q28053WW |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | PDB
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| DrugBank PDB PubMed
| 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 419: 113-20 (2001)
BindingDB Entry DOI: 10.7270/Q2S183SP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50344963
(1-Methylpyrenyl mercapturic acid | CHEMBL1778337)Show SMILES CC(=O)NC(CSCC1=CC=C2C=Cc3cccc4CC=C1C2c34)C(O)=O |c:12,t:8,10,20| Show InChI InChI=1S/C22H21NO3S/c1-13(24)23-19(22(25)26)12-27-11-17-8-7-16-6-5-14-3-2-4-15-9-10-18(17)21(16)20(14)15/h2-8,10,19,21H,9,11-12H2,1H3,(H,23,24)(H,25,26) | PDB
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| CHEMBL KEGG PC cid PC sid UniChem
| Article PubMed
| 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human Oat1 expressed in HEK293 cells |
Bioorg Med Chem 19: 3320-40 (2011)
Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Rattus norvegicus) | BDBM50206509
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16) | PDB
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| 1.58E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Hospital
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
Eur J Pharmacol 409: 31-6 (2001)
BindingDB Entry DOI: 10.7270/Q20Z74JR |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Solute carrier family 22 member 6
(Mus musculus) | BDBM50240408
(1-hexanecarboxylate | CH3-[CH2]5-COO(-) | enanthat...)Show InChI InChI=1S/C7H14O2/c1-2-3-4-5-6-7(8)9/h2-6H2,1H3,(H,8,9)/p-1 | PDB
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KEGG PC cid PC sid PDB UniChem
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| Article PubMed
| 1.67E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr |
J Biol Chem 282: 23841-53 (2007)
Article DOI: 10.1074/jbc.M703467200 BindingDB Entry DOI: 10.7270/Q2W95B35 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM85245
(CAS_36322-90-4 | NSC_4856 | Piroxicam)Show SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O |t:12| Show InChI InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20) | PDB
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| 1.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cells |
Life Sci 69: 2123-35 (2001)
Article DOI: 10.1016/s0024-3205(01)01296-6 BindingDB Entry DOI: 10.7270/Q2XD14JB |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50420189
(CHEMBL1624767)Show InChI InChI=1S/C3H8O3S3/c4-9(5,6)2-3(8)1-7/h3,7-8H,1-2H2,(H,4,5,6) | PDB
Reactome pathway KEGG
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CHEMBL KEGG PC cid PC sid UniChem
| PubMed
| 2.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Arizona
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes |
J Pharmacol Exp Ther 299: 741-7 (2001)
BindingDB Entry DOI: 10.7270/Q2R78GGZ |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50420185
(CHEMBL1233636)Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12) | PDB
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| 2.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake (PAH: 5 uM, indoxyl sulfate:500 uM) in S2 human-OAT1 expressing cells |
Eur J Pharmacol 466: 13-20 (2003)
BindingDB Entry DOI: 10.7270/Q23R0V48 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50420185
(CHEMBL1233636)Show InChI InChI=1S/C8H7NO4S/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8/h1-5,9H,(H,10,11,12) | PDB
Reactome pathway KEGG
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| 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: uptake&inhibition of PAH in OAT1-S2 cells |
Eur J Pharmacol 466: 13-20 (2003)
BindingDB Entry DOI: 10.7270/Q23R0V48 |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50344964
(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)Show InChI InChI=1S/C10H11NO3/c12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13) | PDB
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| 2.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyorin University School of Medicine
Curated by ChEMBL
| Assay Description TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cells |
Eur J Pharmacol 419: 113-20 (2001)
BindingDB Entry DOI: 10.7270/Q2S183SP |
More data for this Ligand-Target Pair | |
Solute carrier family 22 member 6
(Homo sapiens (Human)) | BDBM50344964
(Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-be...)Show InChI InChI=1S/C10H11NO3/c12-9(13)6-7-11-10(14)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13) | PDB
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| Article PubMed
| 2.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description Inhibition of human Oat1 expressed in Drosophila S2 cells |
Bioorg Med Chem 19: 3320-40 (2011)
Article DOI: 10.1016/j.bmc.2011.04.045 BindingDB Entry DOI: 10.7270/Q2TB17WF |
More data for this Ligand-Target Pair | |