BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 21 hits of ic50 for UniProtKB: Q4QYD9   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197959
PNG
(CHEMBL3943485)
Show SMILES CC(C)[C@]1(O)CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\C1 |r,t:8,13,18|
Show InChI InChI=1S/C20H34O/c1-16(2)20(21)14-12-18(4)10-6-8-17(3)9-7-11-19(5)13-15-20/h8,11-12,16,21H,6-7,9-10,13-15H2,1-5H3/b17-8+,18-12+,19-11+/t20-/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 150n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50318484
PNG
(2-((1R,6R)-6-Isopropenyl-3-methyl-cyclohex-2-enyl)...)
Show SMILES CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1 |r,t:11|
Show InChI InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h11-13,17-18,22-23H,2,5-10H2,1,3-4H3/t17-,18+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a 750n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced Ca2+ response preincubated for 5 mins followed by...

Citation and Details

Article DOI: 10.1021/acs.jnatprod.0c00668
BindingDB Entry DOI: 10.7270/Q2ZW1QJH
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197965
PNG
(Incensole)
Show SMILES CC(C)[C@@]12CC[C@@](C)(O1)[C@@H](O)CC\C(C)=C\CC\C(C)=C\C2 |r,t:15,20|
Show InChI InChI=1S/C20H34O2/c1-15(2)20-12-11-17(4)8-6-7-16(3)9-10-18(21)19(5,22-20)13-14-20/h7,11,15,18,21H,6,8-10,12-14H2,1-5H3/b16-7+,17-11+/t18-,19+,20+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem

Patents
Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197958
PNG
(CHEMBL3979367)
Show SMILES CC(C)[C@@]12CC[C@@](C)(O1)[C@H](CC\C(C)=C\CC\C(C)=C\C2)OC(C)=O |r,t:14,19|
Show InChI InChI=1S/C22H36O3/c1-16(2)22-13-12-18(4)9-7-8-17(3)10-11-20(24-19(5)23)21(6,25-22)14-15-22/h8,12,16,20H,7,9-11,13-15H2,1-6H3/b17-8+,18-12+/t20-,21+,22+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197963
PNG
(CHEMBL3983336)
Show SMILES CC(C)[C@@]12CC[C@@](C)(O1)C(=O)CC\C(C)=C\CC\C(C)=C\C2 |r,t:15,20|
Show InChI InChI=1S/C20H32O2/c1-15(2)20-12-11-17(4)8-6-7-16(3)9-10-18(21)19(5,22-20)13-14-20/h7,11,15H,6,8-10,12-14H2,1-5H3/b16-7+,17-11+/t19-,20-/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 5.80E+3n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50548384
PNG
(CHEMBL4762439)
Show SMILES CCCCCc1cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c(O)c1Cc1c(CCCCC)cc(O)c([C@@H]2C=C(C)CC[C@H]2C(C)=C)c1O |r,t:11,38|
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.18E+4n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced Ca2+ response preincubated for 5 mins followed by...

Citation and Details

Article DOI: 10.1021/acs.jnatprod.0c00668
BindingDB Entry DOI: 10.7270/Q2ZW1QJH
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197964
PNG
(CHEMBL3922508)
Show SMILES CC(C)[C@@]12CC[C@@](C)(O1)[C@H](O)CC\C(C)=C\CC\C(C)=C\C2 |r,t:15,20|
Show InChI InChI=1S/C20H34O2/c1-15(2)20-12-11-17(4)8-6-7-16(3)9-10-18(21)19(5,22-20)13-14-20/h7,11,15,18,21H,6,8-10,12-14H2,1-5H3/b16-7+,17-11+/t18-,19-,20-/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.23E+4n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197969
PNG
(CHEMBL3975348)
Show SMILES [H][C@@]12C[C@@]3(CC[C@@](C)(O3)[C@H](CC\C(C)=C\CC[C@]1(C)O2)OC(C)=O)C(C)C |r,t:14|
Show InChI InChI=1S/C22H36O4/c1-15(2)22-13-12-21(6,26-22)18(24-17(4)23)10-9-16(3)8-7-11-20(5)19(14-22)25-20/h8,15,18-19H,7,9-14H2,1-6H3/b16-8+/t18-,19+,20-,21+,22-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.32E+4n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM85747
PNG
(CAS_442-52-4 | CLEMIZOLE HYDROCHLORIDE | NSC_2782 ...)
Show SMILES Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc23)cc1
Show InChI InChI=1S/C19H20ClN3/c20-16-9-7-15(8-10-16)13-23-18-6-2-1-5-17(18)21-19(23)14-22-11-3-4-12-22/h1-2,5-10H,3-4,11-14H2
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
PDB
UniChem

Patents

Similars
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Inhibition of YFP-tagged rat TRPV3 expressed in HEK293 cells assessed as reduction in calcium level by fluo-4 dye based fluorescence assay

J Med Chem 62: 7589-7602 (2019)


Article DOI: 10.1021/acs.jmedchem.8b01954
BindingDB Entry DOI: 10.7270/Q2XS5ZR8
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197970
PNG
(CHEMBL3913521)
Show SMILES [H][C@]12CC\C(C)=C\C[C@@]3(CC[C@@](C)(O3)[C@H](CC[C@@]1(C)O2)OC(C)=O)C(C)C |r,t:5|
Show InChI InChI=1S/C22H36O4/c1-15(2)22-12-9-16(3)7-8-19-20(5,25-19)11-10-18(24-17(4)23)21(6,26-22)13-14-22/h9,15,18-19H,7-8,10-14H2,1-6H3/b16-9+/t18-,19-,20+,21+,22+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.11E+4n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197971
PNG
(CHEMBL3890789)
Show SMILES CC(C)[C@@]12CC[C@@](C)(O1)[C@H](CC\C(C)=C\CC\C(C)=C\C2)OC(=O)Cc1ccccc1 |r,t:14,19|
Show InChI InChI=1S/C28H40O3/c1-21(2)28-17-16-23(4)11-9-10-22(3)14-15-25(27(5,31-28)18-19-28)30-26(29)20-24-12-7-6-8-13-24/h6-8,10,12-13,16,21,25H,9,11,14-15,17-20H2,1-5H3/b22-10+,23-16+/t25-,27+,28+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.17E+4n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197961
PNG
(CHEMBL3899770)
Show SMILES CCCCCCCCC(=O)O[C@H]1CC\C(C)=C\CC\C(C)=C\C[C@@]2(CC[C@@]1(C)O2)C(C)C |r,t:15,20|
Show InChI InChI=1S/C29H50O3/c1-7-8-9-10-11-12-16-27(30)31-26-18-17-24(4)14-13-15-25(5)19-20-29(23(2)3)22-21-28(26,6)32-29/h14,19,23,26H,7-13,15-18,20-22H2,1-6H3/b24-14+,25-19+/t26-,28+,29+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.41E+4n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50535881
PNG
(CHEMBL4535906)
Show SMILES [H][C@@]12Cc3c(OC)c(C)c(OC)c(OC)c3[C@H](N1C(=O)\C(NC2=O)=C\c1cc(OC)c(OC)c(C)c1OC)c1ccccc1 |r|
Show InChI InChI=1S/C33H36N2O8/c1-17-27(39-4)20(15-24(38-3)29(17)41-6)14-22-33(37)35-23(32(36)34-22)16-21-25(26(35)19-12-10-9-11-13-19)31(43-8)30(42-7)18(2)28(21)40-5/h9-15,23,26H,16H2,1-8H3,(H,34,36)/b22-14-/t23-,26+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.43E+4n/an/an/an/an/an/a



National Research Council

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced intracellular calcium accumulation pr...

J Med Chem 59: 5661-83 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01448
BindingDB Entry DOI: 10.7270/Q2222Z8V
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197962
PNG
(CHEMBL3894504)
Show SMILES [H][C@@]12CC\C(C)=C\[C@]3([H])OCC(C)=C3CC\C(C)=C\CC[C@]1(C)O2 |r,c:12,t:5,18|
Show InChI InChI=1S/C20H30O2/c1-14-6-5-11-20(4)19(22-20)10-8-15(2)12-18-17(9-7-14)16(3)13-21-18/h6,12,18-19H,5,7-11,13H2,1-4H3/b14-6+,15-12+/t18-,19+,20-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5.75E+4n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50535869
PNG
(CHEMBL4576619)
Show SMILES COc1cc2CCN([C@@H](c3ccc(F)cc3)c2cc1OC)C(=O)N1CCc2cc(OC)c(OC)cc2[C@@H]1c1ccc(F)cc1 |r|
Show InChI InChI=1S/C35H34F2N2O5/c1-41-29-17-23-13-15-38(33(27(23)19-31(29)43-3)21-5-9-25(36)10-6-21)35(40)39-16-14-24-18-30(42-2)32(44-4)20-28(24)34(39)22-7-11-26(37)12-8-22/h5-12,17-20,33-34H,13-16H2,1-4H3/t33-,34-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.29E+4n/an/an/an/an/an/a



National Research Council

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced intracellular calcium accumulation pr...

J Med Chem 59: 5661-83 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01448
BindingDB Entry DOI: 10.7270/Q2222Z8V
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197967
PNG
(CHEMBL3948101)
Show SMILES CC(C)[C@@]12CC[C@@](C)(O1)[C@H](CC\C(C)=C\CC\C(C)=C\C2)OC(=O)\C=C\c1ccccc1 |r,t:14,19|
Show InChI InChI=1S/C29H40O3/c1-22(2)29-19-18-24(4)11-9-10-23(3)14-16-26(28(5,32-29)20-21-29)31-27(30)17-15-25-12-7-6-8-13-25/h6-8,10,12-13,15,17-18,22,26H,9,11,14,16,19-21H2,1-5H3/b17-15+,23-10+,24-18+/t26-,28+,29+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 9.44E+4n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50535866
PNG
(CHEMBL4588287)
Show SMILES COc1cc2CCN([C@@H](c3ccc(Cl)cc3)c2cc1OC)C(=O)N1CCc2cc(OC)c(OC)cc2[C@@H]1c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C35H34Cl2N2O5/c1-41-29-17-23-13-15-38(33(27(23)19-31(29)43-3)21-5-9-25(36)10-6-21)35(40)39-16-14-24-18-30(42-2)32(44-4)20-28(24)34(39)22-7-11-26(37)12-8-22/h5-12,17-20,33-34H,13-16H2,1-4H3/t33-,34-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National Research Council

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced intracellular calcium accumulation pr...

J Med Chem 59: 5661-83 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01448
BindingDB Entry DOI: 10.7270/Q2222Z8V
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197960
PNG
(CHEMBL3931428)
Show SMILES [H][C@@]12CC\C(C)=C\[C@]3([H])OC(=O)C(C)=C3CC\C(C)=C\CC[C@]1(C)O2 |r,c:13,t:5,19|
Show InChI InChI=1S/C20H28O3/c1-13-6-5-11-20(4)18(23-20)10-8-14(2)12-17-16(9-7-13)15(3)19(21)22-17/h6,12,17-18H,5,7-11H2,1-4H3/b13-6+,14-12+/t17-,18+,20-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197966
PNG
(CHEMBL3959869)
Show SMILES CC(C)[C@@]12CC[C@@](C)(O1)[C@H](CC\C(C)=C\CC\C(C)=C\C2)OC(=O)c1ccccc1 |r,t:14,19|
Show InChI InChI=1S/C27H38O3/c1-20(2)27-17-16-22(4)11-9-10-21(3)14-15-24(26(5,30-27)18-19-27)29-25(28)23-12-7-6-8-13-23/h6-8,10,12-13,16,20,24H,9,11,14-15,17-19H2,1-5H3/b21-10+,22-16+/t24-,26+,27+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50197968
PNG
(CHEMBL3904515)
Show SMILES [H][C@@]12C[C@@]3(CC[C@@](C)(O3)[C@@H](O)CC\C(C)=C\CC[C@]1(C)O2)C(C)C |r,t:15|
Show InChI InChI=1S/C20H34O3/c1-14(2)20-12-11-18(4,23-20)16(21)9-8-15(3)7-6-10-19(5)17(13-20)22-19/h7,14,16-17,21H,6,8-13H2,1-5H3/b15-7+/t16-,17+,18+,19-,20-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Universit£ del Piemonte Orientale

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV3 overexpressed in HEK293 cells assessed as inhibition of thymol-induced increase in intracellular Ca2+ levels preincu...

J Nat Prod 79: 1762-8 (2016)


Article DOI: 10.1021/acs.jnatprod.6b00141
BindingDB Entry DOI: 10.7270/Q2PC34BW
More data for this
Ligand-Target Pair
Heat sensitive channel TRPV3


(Rattus norvegicus)		BDBM50535865
PNG
(CHEMBL4543647)
Show SMILES COc1cc2CCN([C@@H](c3ccccc3)c2cc1OC)C(=O)N1CCc2cc(OC)c(OC)cc2[C@@H]1c1ccccc1 |r|
Show InChI InChI=1S/C35H36N2O5/c1-39-29-19-25-15-17-36(33(23-11-7-5-8-12-23)27(25)21-31(29)41-3)35(38)37-18-16-26-20-30(40-2)32(42-4)22-28(26)34(37)24-13-9-6-10-14-24/h5-14,19-22,33-34H,15-18H2,1-4H3/t33-,34-/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



National Research Council

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant rat TRPV3 expressed in HEK293 cells assessed as inhibition of thymol-induced intracellular calcium accumulation pr...

J Med Chem 59: 5661-83 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01448
BindingDB Entry DOI: 10.7270/Q2222Z8V
More data for this
Ligand-Target Pair